| Dataset | Carcinogenome Chemical Perturbation Carcinogenicity Signatures |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | omeprazole 11.11 um perturbation at 24 h in MCF10A.TP53.M (Carcinogenome) |
| Similar Terms | |
| Downloads & Tools |
101 genes differentially expressed following the CRCGN017_MCF10A.TP53.M_24H:D03 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| PAF1 | Paf1, RNA polymerase II associated factor, homolog (S. cerevisiae) | 5.61865 |
| PPP1R13B | protein phosphatase 1, regulatory subunit 13B | 5.60595 |
| KLHL21 | kelch-like family member 21 | 4.96705 |
| TBPL1 | TBP-like 1 | 3.6543 |
| RBP4 | retinol binding protein 4, plasma | 3.5441 |
| ACAA1 | acetyl-CoA acyltransferase 1 | 3.30183 |
| RBKS | ribokinase | 3.0362 |
| PPM1D | protein phosphatase, Mg2+/Mn2+ dependent, 1D | 2.8547 |
| APPBP2 | amyloid beta precursor protein (cytoplasmic tail) binding protein 2 | 2.75036 |
| AP1B1 | adaptor-related protein complex 1, beta 1 subunit | 2.7139 |
| GARRE1 | granule associated Rac and RHOG effector 1 | 2.66535 |
| MGAM | maltase-glucoamylase | 2.58035 |
| RCOR3 | REST corepressor 3 | 2.5618 |
| MSRA | methionine sulfoxide reductase A | 2.47335 |
| DPM3 | dolichyl-phosphate mannosyltransferase polypeptide 3 | 2.44735 |
| MNAT1 | MNAT CDK-activating kinase assembly factor 1 | 2.41945 |
| GPATCH1 | G patch domain containing 1 | 2.4156 |
| HLF | hepatic leukemia factor | 2.41142 |
| TRAPPC11 | trafficking protein particle complex 11 | 2.4049 |
| PDE9A | phosphodiesterase 9A | 2.40205 |
| VPS45 | vacuolar protein sorting 45 homolog (S. cerevisiae) | 2.37025 |
| FBXL2 | F-box and leucine-rich repeat protein 2 | 2.346 |
| ARHGAP29 | Rho GTPase activating protein 29 | 2.32615 |
| E4F1 | E4F transcription factor 1 | 2.2773 |
| ZNF280D | zinc finger protein 280D | 2.2762 |
| ATAD2B | ATPase family, AAA domain containing 2B | 2.2735 |
| TMEM183A | transmembrane protein 183A | 2.26498 |
| EXOC1 | exocyst complex component 1 | 2.26375 |
| ACYP2 | acylphosphatase 2, muscle type | 2.2286 |
| MMUT | methylmalonyl-CoA mutase | 2.2095 |
| NOTCH1 | notch 1 | 2.20185 |
| WDR7 | WD repeat domain 7 | 2.18875 |
| CDKN2AIP | CDKN2A interacting protein | 2.1753 |
| PISD | phosphatidylserine decarboxylase | 2.1639 |
| NID2 | nidogen 2 (osteonidogen) | 2.1545 |
| CFI | complement factor I | 2.1512 |
| CRIPT | cysteine-rich PDZ-binding protein | 2.13255 |
| COG2 | component of oligomeric golgi complex 2 | 2.1234 |
| ZNF586 | zinc finger protein 586 | 2.12165 |
| CREB1 | cAMP responsive element binding protein 1 | 2.111 |
| ZNF571 | zinc finger protein 571 | 2.0945 |
| PDZRN3 | PDZ domain containing ring finger 3 | 2.09405 |
| PDK2 | pyruvate dehydrogenase kinase, isozyme 2 | 2.09188 |
| CLEC5A | C-type lectin domain family 5, member A | 2.08385 |
| ZSCAN26 | zinc finger and SCAN domain containing 26 | 2.07625 |
| HEATR6 | HEAT repeat containing 6 | 2.07442 |
| TRIM13 | tripartite motif containing 13 | 2.0739 |
| SLC75A1 | solute carrier family 75 member 1 | 2.06985 |
| DUSP11 | dual specificity phosphatase 11 (RNA/RNP complex 1-interacting) | 2.0664 |
| TAF11 | TAF11 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 28kDa | 2.06305 |
| SNX7 | sorting nexin 7 | 2.03175 |
| NDEL1 | nudE neurodevelopment protein 1-like 1 | 2.0305 |
| HPGDS | hematopoietic prostaglandin D synthase | 2.01935 |
| CASD1 | CAS1 domain containing 1 | 2.01915 |
| KIT | v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog | 2.012 |
| Symbol | Name | Standardized Value |
|---|---|---|
| HSPA8 | heat shock 70kDa protein 8 | -5.6627 |
| KRT14 | keratin 14, type I | -5.0 |
| LAP3 | leucine aminopeptidase 3 | -4.8785 |
| TXNDC9 | thioredoxin domain containing 9 | -4.69128 |
| HAT1 | histone acetyltransferase 1 | -4.44765 |
| CD44 | CD44 molecule (Indian blood group) | -4.20727 |
| STARD7 | StAR-related lipid transfer (START) domain containing 7 | -3.4189 |
| CANT1 | calcium activated nucleotidase 1 | -3.21698 |
| G3BP1 | GTPase activating protein (SH3 domain) binding protein 1 | -3.20585 |
| FABP5 | fatty acid binding protein 5 (psoriasis-associated) | -3.0197 |
| MSN | moesin | -2.75025 |
| ANXA2 | annexin A2 | -2.62568 |
| CD70 | CD70 molecule | -2.61945 |
| HNRNPAB | heterogeneous nuclear ribonucleoprotein A/B | -2.56395 |
| PSMA6 | proteasome (prosome, macropain) subunit, alpha type, 6 | -2.53585 |
| ATOX1 | antioxidant 1 copper chaperone | -2.5163 |
| TIMP1 | TIMP metallopeptidase inhibitor 1 | -2.4905 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -2.42985 |
| RPS6KA4 | ribosomal protein S6 kinase, 90kDa, polypeptide 4 | -2.4153 |
| PABPC3 | poly(A) binding protein, cytoplasmic 3 | -2.39055 |
| ETFB | electron-transfer-flavoprotein, beta polypeptide | -2.3522 |
| CCT4 | chaperonin containing TCP1, subunit 4 (delta) | -2.29195 |
| PPP2R5E | protein phosphatase 2, regulatory subunit B', epsilon isoform | -2.27535 |
| ATIC | 5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase | -2.2441 |
| FAM222B | family with sequence similarity 222, member B | -2.23745 |
| IRAK1 | interleukin-1 receptor-associated kinase 1 | -2.23365 |
| AIMP2 | aminoacyl tRNA synthetase complex-interacting multifunctional protein 2 | -2.21445 |
| UBA52 | ubiquitin A-52 residue ribosomal protein fusion product 1 | -2.21435 |
| FHL2 | four and a half LIM domains 2 | -2.20665 |
| TMPRSS6 | transmembrane protease, serine 6 | -2.2015 |
| MMADHC | methylmalonic aciduria (cobalamin deficiency) cblD type, with homocystinuria | -2.19465 |
| RPL12 | ribosomal protein L12 | -2.1809 |
| ARPC5L | actin related protein 2/3 complex, subunit 5-like | -2.17295 |
| KARS1 | lysyl-tRNA synthetase 1 | -2.15298 |
| RPL37 | ribosomal protein L37 | -2.1513 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | -2.1313 |
| AATF | apoptosis antagonizing transcription factor | -2.1098 |
| NUDT18 | nudix (nucleoside diphosphate linked moiety X)-type motif 18 | -2.10735 |
| RLIM | ring finger protein, LIM domain interacting | -2.10115 |
| RPL6 | ribosomal protein L6 | -2.09 |
| RCN1 | reticulocalbin 1, EF-hand calcium binding domain | -2.0595 |
| GORASP2 | golgi reassembly stacking protein 2, 55kDa | -2.04763 |
| CHRNB2 | cholinergic receptor, nicotinic, beta 2 (neuronal) | -2.0333 |
| CERS6 | ceramide synthase 6 | -2.0253 |
| CD81 | CD81 molecule | -2.0191 |
| ZBED1 | zinc finger, BED-type containing 1 | -2.0142 |
