CRCGN017_MCF10A.TP53.M_24H:D05 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description s26948 3.33 um perturbation at 24 h in MCF10A.TP53.M (Carcinogenome)
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Genes

33 genes differentially expressed following the CRCGN017_MCF10A.TP53.M_24H:D05 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
E2F2 E2F transcription factor 2 4.17845
SPAG4 sperm associated antigen 4 4.05925
ADGRE5 adhesion G protein-coupled receptor E5 3.92759
KCTD5 potassium channel tetramerization domain containing 5 3.67414
RELB v-rel avian reticuloendotheliosis viral oncogene homolog B 3.54008
CXCR4 chemokine (C-X-C motif) receptor 4 3.51163
AGR2 anterior gradient 2 3.42872
MCUR1 mitochondrial calcium uniporter regulator 1 3.16646
ADRB2 adrenoceptor beta 2, surface 2.80431
BZW2 basic leucine zipper and W2 domains 2 2.77027
DHRS2 dehydrogenase/reductase (SDR family) member 2 2.34659
EIF3H eukaryotic translation initiation factor 3, subunit H 2.16696
S100A3 S100 calcium binding protein A3 2.14931
KRT33A keratin 33A, type I 2.06859
MRFAP1L1 Morf4 family associated protein 1-like 1 2.03548

decreased expression

Symbol Name Standardized Value
HMG20B high mobility group 20B -6.25786
ACOT9 acyl-CoA thioesterase 9 -3.99437
NPDC1 neural proliferation, differentiation and control, 1 -3.97669
DNAJA3 DnaJ (Hsp40) homolog, subfamily A, member 3 -3.9643
HAT1 histone acetyltransferase 1 -3.36332
PPP2R5E protein phosphatase 2, regulatory subunit B', epsilon isoform -3.31631
NSDHL NAD(P) dependent steroid dehydrogenase-like -3.18236
COG2 component of oligomeric golgi complex 2 -3.10981
MAP4K3 mitogen-activated protein kinase kinase kinase kinase 3 -2.52991
LPGAT1 lysophosphatidylglycerol acyltransferase 1 -2.42677
MGRN1 mahogunin ring finger 1, E3 ubiquitin protein ligase -2.28495
THAP11 THAP domain containing 11 -2.19845
MFSD12 major facilitator superfamily domain containing 12 -2.19599
ZC3H7A zinc finger CCCH-type containing 7A -2.14564
LRCH3 leucine-rich repeats and calponin homology (CH) domain containing 3 -2.13912
GDF15 growth differentiation factor 15 -2.05367
LOC127933115 uncharacterized LOC127933115 -2.04086
APOO apolipoprotein O -2.03712