CRCGN017_MCF10A.TP53.M_24H:D07 Gene Set
Genes
48 genes differentially expressed following the CRCGN017_MCF10A.TP53.M_24H:D07 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
HOXA5
|
homeobox A5
|
6.72053
|
|
TCEA2
|
transcription elongation factor A (SII), 2
|
4.3025
|
|
KCTD5
|
potassium channel tetramerization domain containing 5
|
3.78233
|
|
DYRK3
|
dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3
|
3.59783
|
|
RPL39L
|
ribosomal protein L39-like
|
3.32653
|
|
SNAP25
|
synaptosomal-associated protein, 25kDa
|
3.23282
|
|
IL1B
|
interleukin 1, beta
|
3.2025
|
|
EPN2
|
epsin 2
|
2.81596
|
|
KLHL9
|
kelch-like family member 9
|
2.78713
|
|
INPP4B
|
inositol polyphosphate-4-phosphatase, type II, 105kDa
|
2.5271
|
|
IGHMBP2
|
immunoglobulin mu binding protein 2
|
2.46995
|
|
LBR
|
lamin B receptor
|
2.423
|
|
HMOX1
|
heme oxygenase 1
|
2.36845
|
|
PKIG
|
protein kinase (cAMP-dependent, catalytic) inhibitor gamma
|
2.33767
|
|
NRIP1
|
nuclear receptor interacting protein 1
|
2.32935
|
|
POLD4
|
polymerase (DNA-directed), delta 4, accessory subunit
|
2.27488
|
|
ALDH1A3
|
aldehyde dehydrogenase 1 family, member A3
|
2.23725
|
|
HOXA10
|
homeobox A10
|
2.21559
|
|
HOXA4
|
homeobox A4
|
2.17273
|
|
FHL2
|
four and a half LIM domains 2
|
2.13934
|
|
GNA15
|
guanine nucleotide binding protein (G protein), alpha 15 (Gq class)
|
2.119
|
|
NSG2
|
neuronal vesicle trafficking associated 2
|
2.10255
|
|
NKX2-2
|
NK2 homeobox 2
|
2.09698
|
|
HOXA7
|
homeobox A7
|
2.07468
|
|
PCNA
|
proliferating cell nuclear antigen
|
2.03198
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
KRT14
|
keratin 14, type I
|
-6.44271
|
|
NSDHL
|
NAD(P) dependent steroid dehydrogenase-like
|
-3.80438
|
|
MSMO1
|
methylsterol monooxygenase 1
|
-3.65996
|
|
TUBA4A
|
tubulin, alpha 4a
|
-3.59218
|
|
PUF60
|
poly-U binding splicing factor 60KDa
|
-3.47353
|
|
S100A4
|
S100 calcium binding protein A4
|
-3.45918
|
|
HMGCS1
|
3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)
|
-3.3704
|
|
RGS2
|
regulator of G-protein signaling 2
|
-3.25768
|
|
UFM1
|
ubiquitin-fold modifier 1
|
-3.16595
|
|
ACOT9
|
acyl-CoA thioesterase 9
|
-2.63374
|
|
CTNND1
|
catenin (cadherin-associated protein), delta 1
|
-2.60123
|
|
DSG1
|
desmoglein 1
|
-2.5961
|
|
HMGCR
|
3-hydroxy-3-methylglutaryl-CoA reductase
|
-2.55299
|
|
IGF2BP2
|
insulin-like growth factor 2 mRNA binding protein 2
|
-2.41107
|
|
SYNE2
|
spectrin repeat containing, nuclear envelope 2
|
-2.38188
|
|
ATP11B
|
ATPase, class VI, type 11B
|
-2.20994
|
|
SNCA
|
synuclein, alpha (non A4 component of amyloid precursor)
|
-2.19824
|
|
FSHB
|
follicle stimulating hormone, beta polypeptide
|
-2.16218
|
|
BASP1
|
brain abundant, membrane attached signal protein 1
|
-2.14316
|
|
G3BP1
|
GTPase activating protein (SH3 domain) binding protein 1
|
-2.05593
|
|
POMC
|
proopiomelanocortin
|
-2.03327
|
|
LCE2B
|
late cornified envelope 2B
|
-2.01937
|
|
FLG
|
filaggrin
|
-2.01453
|
