CRCGN017_MCF10A.TP53.M_24H:D09 Gene Set
Genes
45 genes differentially expressed following the CRCGN017_MCF10A.TP53.M_24H:D09 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
TCEA2
|
transcription elongation factor A (SII), 2
|
6.24605
|
|
HOXA5
|
homeobox A5
|
5.76835
|
|
EPHB2
|
EPH receptor B2
|
3.4402
|
|
MAMLD1
|
mastermind-like domain containing 1
|
3.21122
|
|
LGMN
|
legumain
|
3.07996
|
|
IL1B
|
interleukin 1, beta
|
2.9479
|
|
ABCC5
|
ATP-binding cassette, sub-family C (CFTR/MRP), member 5
|
2.83254
|
|
NRIP1
|
nuclear receptor interacting protein 1
|
2.79066
|
|
FHL2
|
four and a half LIM domains 2
|
2.4606
|
|
CCL2
|
chemokine (C-C motif) ligand 2
|
2.45535
|
|
PDLIM1
|
PDZ and LIM domain 1
|
2.43234
|
|
DNAJB1
|
DnaJ (Hsp40) homolog, subfamily B, member 1
|
2.4045
|
|
PLSCR1
|
phospholipid scramblase 1
|
2.38634
|
|
NFKBIE
|
nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, epsilon
|
2.3431
|
|
PLAT
|
plasminogen activator, tissue
|
2.33839
|
|
RBP4
|
retinol binding protein 4, plasma
|
2.31972
|
|
HOXA4
|
homeobox A4
|
2.28647
|
|
LHX6
|
LIM homeobox 6
|
2.23993
|
|
RIPPLY2-CYB5R4
|
RIPPLY2-CYB5R4 readthrough
|
2.21701
|
|
AGR2
|
anterior gradient 2
|
2.20073
|
|
SLC5A6
|
solute carrier family 5 (sodium/multivitamin and iodide cotransporter), member 6
|
2.14052
|
|
TSPAN6
|
tetraspanin 6
|
2.11089
|
|
HERC6
|
HECT and RLD domain containing E3 ubiquitin protein ligase family member 6
|
2.06597
|
|
GTPBP8
|
GTP-binding protein 8 (putative)
|
2.04386
|
|
PRPF18
|
pre-mRNA processing factor 18
|
2.02612
|
|
ELOVL6
|
ELOVL fatty acid elongase 6
|
2.02513
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
KRT14
|
keratin 14, type I
|
-8.27785
|
|
RGS2
|
regulator of G-protein signaling 2
|
-4.18808
|
|
CHMP4B
|
charged multivesicular body protein 4B
|
-4.09416
|
|
NUP85
|
nucleoporin 85kDa
|
-3.11983
|
|
S100A4
|
S100 calcium binding protein A4
|
-3.03776
|
|
CCNB2
|
cyclin B2
|
-2.84011
|
|
NT5DC2
|
5'-nucleotidase domain containing 2
|
-2.6373
|
|
PIH1D1
|
PIH1 domain containing 1
|
-2.57155
|
|
MRPS7
|
mitochondrial ribosomal protein S7
|
-2.31874
|
|
TAC4
|
tachykinin 4 (hemokinin)
|
-2.28332
|
|
NRDC
|
nardilysin convertase
|
-2.23415
|
|
NT5C
|
5', 3'-nucleotidase, cytosolic
|
-2.17022
|
|
KCTD2
|
potassium channel tetramerization domain containing 2
|
-2.1077
|
|
SPAG7
|
sperm associated antigen 7
|
-2.06999
|
|
BCL2L2
|
BCL2-like 2
|
-2.05768
|
|
NAT9
|
N-acetyltransferase 9 (GCN5-related, putative)
|
-2.05445
|
|
XRCC1
|
X-ray repair complementing defective repair in Chinese hamster cells 1
|
-2.04866
|
|
RAB5B
|
RAB5B, member RAS oncogene family
|
-2.04663
|
|
FXR2
|
fragile X mental retardation, autosomal homolog 2
|
-2.04454
|