CRCGN017_MCF10A.TP53.M_24H:D11 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description lg100754 0.33 um perturbation at 24 h in MCF10A.TP53.M (Carcinogenome)
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Genes

15 genes differentially expressed following the CRCGN017_MCF10A.TP53.M_24H:D11 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
CDCA4 cell division cycle associated 4 5.02483
SSBP2 single-stranded DNA binding protein 2 4.24149
SPAG4 sperm associated antigen 4 4.21878
HOXA5 homeobox A5 3.85201
PLEKHJ1 pleckstrin homology domain containing, family J member 1 3.12386
CCL2 chemokine (C-C motif) ligand 2 2.6297
EPHB2 EPH receptor B2 2.39055
NRIP1 nuclear receptor interacting protein 1 2.00354
TLCD3A TLC domain containing 3A 2.00249

decreased expression

Symbol Name Standardized Value
PSMB8 proteasome (prosome, macropain) subunit, beta type, 8 -4.35032
ISOC1 isochorismatase domain containing 1 -3.04212
COG2 component of oligomeric golgi complex 2 -2.80191
PSIP1 PC4 and SFRS1 interacting protein 1 -2.77497
PSMB9 proteasome (prosome, macropain) subunit, beta type, 9 -2.41932
ERC2 ELKS/RAB6-interacting/CAST family member 2 -2.10552