CRCGN017_MCF10A.TP53.M_24H:D12 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description lg100754 0.11 um perturbation at 24 h in MCF10A.TP53.M (Carcinogenome)
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Genes

20 genes differentially expressed following the CRCGN017_MCF10A.TP53.M_24H:D12 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
PDLIM1 PDZ and LIM domain 1 3.79312
PACSIN3 protein kinase C and casein kinase substrate in neurons 3 3.72369
CCP110 centriolar coiled coil protein 110kDa 3.42227
DUSP11 dual specificity phosphatase 11 (RNA/RNP complex 1-interacting) 3.41242
TLCD3A TLC domain containing 3A 2.96273
IQGAP1 IQ motif containing GTPase activating protein 1 2.88111
CNRIP1 cannabinoid receptor interacting protein 1 2.74875
BAG3 BCL2-associated athanogene 3 2.51978
HOXA5 homeobox A5 2.46398
CHN1 chimerin 1 2.34407
SLC5A6 solute carrier family 5 (sodium/multivitamin and iodide cotransporter), member 6 2.03615

decreased expression

Symbol Name Standardized Value
DHRS7 dehydrogenase/reductase (SDR family) member 7 -4.57566
HSPA8 heat shock 70kDa protein 8 -3.56766
REEP5 receptor accessory protein 5 -3.17312
GDF15 growth differentiation factor 15 -2.87953
TOMM70 translocase of outer mitochondrial membrane 70 -2.43334
DSE dermatan sulfate epimerase -2.3835
PPP2R5E protein phosphatase 2, regulatory subunit B', epsilon isoform -2.3106
ALDH7A1 aldehyde dehydrogenase 7 family, member A1 -2.14686
LSM5 LSM5 homolog, U6 small nuclear RNA associated (S. cerevisiae) -2.12041