CRCGN017_MCF10A.TP53.M_24H:D14 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description galangin with tcdd perturbation at 24 h in MCF10A.TP53.M (Carcinogenome)
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Genes

22 genes differentially expressed following the CRCGN017_MCF10A.TP53.M_24H:D14 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
SPAG4 sperm associated antigen 4 4.57709
E2F2 E2F transcription factor 2 4.01334
AXIN1 axin 1 3.16698
CCL2 chemokine (C-C motif) ligand 2 3.11489
MSRA methionine sulfoxide reductase A 2.83733
TPD52L2 tumor protein D52-like 2 2.54916
FOXRED2 FAD-dependent oxidoreductase domain containing 2 2.42517
SLC25A14 solute carrier family 25 (mitochondrial carrier, brain), member 14 2.42175
ABHD6 abhydrolase domain containing 6 2.41802
TESK1 testis-specific kinase 1 2.31344
KLHL21 kelch-like family member 21 2.16647
TLCD3A TLC domain containing 3A 2.14002
NCKAP1 NCK-associated protein 1 2.10803
TBXA2R thromboxane A2 receptor 2.03718
MAMLD1 mastermind-like domain containing 1 2.01829
NKX2-2 NK2 homeobox 2 2.01637

decreased expression

Symbol Name Standardized Value
C2CD5 C2 calcium-dependent domain containing 5 -4.36074
CNDP2 CNDP dipeptidase 2 (metallopeptidase M20 family) -4.25378
PMM2 phosphomannomutase 2 -2.96871
DIPK1A divergent protein kinase domain 1A -2.73985
TIPARP TCDD-inducible poly(ADP-ribose) polymerase -2.38603
BAX BCL2-associated X protein -2.11319