CRCGN017_MCF10A.TP53.M_24H:D15 Gene Set
Genes
42 genes differentially expressed following the CRCGN017_MCF10A.TP53.M_24H:D15 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
DDX42
|
DEAD (Asp-Glu-Ala-Asp) box helicase 42
|
5.4189
|
|
ADGRE5
|
adhesion G protein-coupled receptor E5
|
4.43455
|
|
RELB
|
v-rel avian reticuloendotheliosis viral oncogene homolog B
|
4.20887
|
|
TXNL4B
|
thioredoxin-like 4B
|
3.19295
|
|
MSRA
|
methionine sulfoxide reductase A
|
2.83795
|
|
TBC1D31
|
TBC1 domain family, member 31
|
2.4438
|
|
NGRN
|
neugrin, neurite outgrowth associated
|
2.42724
|
|
ZBTB5
|
zinc finger and BTB domain containing 5
|
2.4056
|
|
TFDP2
|
transcription factor Dp-2 (E2F dimerization partner 2)
|
2.23184
|
|
TGFB3
|
transforming growth factor, beta 3
|
2.20756
|
|
ZNF532
|
zinc finger protein 532
|
2.15264
|
|
PDGFRB
|
platelet-derived growth factor receptor, beta polypeptide
|
2.11834
|
|
APEX2
|
APEX nuclease (apurinic/apyrimidinic endonuclease) 2
|
2.11832
|
|
MISP
|
mitotic spindle positioning
|
2.11688
|
|
GSTM2
|
glutathione S-transferase mu 2 (muscle)
|
2.11014
|
|
NAP1L3
|
nucleosome assembly protein 1-like 3
|
2.10966
|
|
SMIM40
|
small integral membrane protein 40
|
2.10446
|
|
SPIN2B
|
spindlin family, member 2B
|
2.10012
|
|
BTK
|
Bruton agammaglobulinemia tyrosine kinase
|
2.04388
|
|
GRB7
|
growth factor receptor-bound protein 7
|
2.01299
|
|
FAT1
|
FAT atypical cadherin 1
|
2.01117
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
IARS2
|
isoleucyl-tRNA synthetase 2, mitochondrial
|
-5.35291
|
|
NPDC1
|
neural proliferation, differentiation and control, 1
|
-4.55271
|
|
SCYL3
|
SCY1-like 3 (S. cerevisiae)
|
-4.54148
|
|
LAP3
|
leucine aminopeptidase 3
|
-4.25491
|
|
UBE3C
|
ubiquitin protein ligase E3C
|
-4.05139
|
|
MSMO1
|
methylsterol monooxygenase 1
|
-3.75397
|
|
NSDHL
|
NAD(P) dependent steroid dehydrogenase-like
|
-3.47197
|
|
TIPARP
|
TCDD-inducible poly(ADP-ribose) polymerase
|
-3.23803
|
|
THAP11
|
THAP domain containing 11
|
-3.01802
|
|
MSN
|
moesin
|
-2.78486
|
|
ILK
|
integrin-linked kinase
|
-2.75815
|
|
PPP2R3C
|
protein phosphatase 2, regulatory subunit B'', gamma
|
-2.74011
|
|
TXNRD1
|
thioredoxin reductase 1
|
-2.67677
|
|
NFKBIA
|
nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha
|
-2.58243
|
|
BCAP31
|
B-cell receptor-associated protein 31
|
-2.53991
|
|
DNAJB6
|
DnaJ (Hsp40) homolog, subfamily B, member 6
|
-2.53126
|
|
CST3
|
cystatin C
|
-2.44507
|
|
CUL1
|
cullin 1
|
-2.27043
|
|
CCDC85C
|
coiled-coil domain containing 85C
|
-2.07131
|
|
PSMD6
|
proteasome (prosome, macropain) 26S subunit, non-ATPase, 6
|
-2.05083
|
|
AK4
|
adenylate kinase 4
|
-2.01481
|
