CRCGN017_MCF10A.TP53.M_24H:D16 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description chlorpropamide 100.46 um perturbation at 24 h in MCF10A.TP53.M (Carcinogenome)
Similar Terms
Downloads & Tools

Genes

29 genes differentially expressed following the CRCGN017_MCF10A.TP53.M_24H:D16 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
RRS1 RRS1 ribosome biogenesis regulator homolog (S. cerevisiae) 6.89081
AGR2 anterior gradient 2 3.28486
SNAP25 synaptosomal-associated protein, 25kDa 3.10975
TCFL5 transcription factor-like 5 (basic helix-loop-helix) 2.93483
IDE insulin-degrading enzyme 2.75305
SIRT3 sirtuin 3 2.74675
PRKCH protein kinase C, eta 2.7252
OLFML2B olfactomedin-like 2B 2.34522
IGHMBP2 immunoglobulin mu binding protein 2 2.32762
TPD52L2 tumor protein D52-like 2 2.31216
MAST2 microtubule associated serine/threonine kinase 2 2.24924
CADM1 cell adhesion molecule 1 2.19854
ATP6V1B2 ATPase, H+ transporting, lysosomal 56/58kDa, V1 subunit B2 2.196
COPS5 COP9 signalosome subunit 5 2.1199
VGLL4 vestigial-like family member 4 2.05453

decreased expression

Symbol Name Standardized Value
DYNLT3 dynein, light chain, Tctex-type 3 -3.62246
PPP2R5E protein phosphatase 2, regulatory subunit B', epsilon isoform -3.49509
HMG20B high mobility group 20B -3.43887
GOLT1B golgi transport 1B -3.30316
WASHC4 WASH complex subunit 4 -2.88798
VAT1 vesicle amine transport 1 -2.80016
EXT1 exostosin glycosyltransferase 1 -2.75585
LPGAT1 lysophosphatidylglycerol acyltransferase 1 -2.36072
CFHR2 complement factor H-related 2 -2.33074
ARNT2 aryl-hydrocarbon receptor nuclear translocator 2 -2.28652
KRT14 keratin 14, type I -2.26246
TUBA4A tubulin, alpha 4a -2.20055
AP1M2 adaptor-related protein complex 1, mu 2 subunit -2.15323
RND3 Rho family GTPase 3 -2.06813