CRCGN017_MCF10A.TP53.M_24H:D20 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description 2-aminofluorene 33.05 um perturbation at 24 h in MCF10A.TP53.M (Carcinogenome)
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Genes

20 genes differentially expressed following the CRCGN017_MCF10A.TP53.M_24H:D20 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
SPAG4 sperm associated antigen 4 6.32549
ABCC5 ATP-binding cassette, sub-family C (CFTR/MRP), member 5 4.22818
PNKP polynucleotide kinase 3'-phosphatase 4.1317
EAPP E2F-associated phosphoprotein 4.10387
SNX11 sorting nexin 11 2.51128
TUBB6 tubulin, beta 6 class V 2.3113
HMGA2 high mobility group AT-hook 2 2.2664
EVL Enah/Vasp-like 2.21201
CENPE centromere protein E, 312kDa 2.17999
PDLIM1 PDZ and LIM domain 1 2.08667
KLF10 Kruppel-like factor 10 2.00989

decreased expression

Symbol Name Standardized Value
HAT1 histone acetyltransferase 1 -3.84924
PMM2 phosphomannomutase 2 -3.37299
ADI1 acireductone dioxygenase 1 -3.34265
PARP2 poly (ADP-ribose) polymerase 2 -2.98232
PCNA proliferating cell nuclear antigen -2.71966
TKT transketolase -2.59257
CD320 CD320 molecule -2.2828
DNAJC15 DnaJ (Hsp40) homolog, subfamily C, member 15 -2.0945
ZMYM2 zinc finger, MYM-type 2 -2.03327