CRCGN017_MCF10A.TP53.M_24H:D21 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description 2-aminofluorene 11.02 um perturbation at 24 h in MCF10A.TP53.M (Carcinogenome)
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Genes

18 genes differentially expressed following the CRCGN017_MCF10A.TP53.M_24H:D21 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
SNAP25 synaptosomal-associated protein, 25kDa 3.71218
ADO 2-aminoethanethiol (cysteamine) dioxygenase 3.6912
ANO10 anoctamin 10 3.22326
UBR7 ubiquitin protein ligase E3 component n-recognin 7 (putative) 2.74482
PHKA1 phosphorylase kinase, alpha 1 (muscle) 2.47914
VGLL4 vestigial-like family member 4 2.47794
GATA2 GATA binding protein 2 2.30964
MSRA methionine sulfoxide reductase A 2.10994
CDK19 cyclin-dependent kinase 19 2.01887

decreased expression

Symbol Name Standardized Value
PHKG2 phosphorylase kinase, gamma 2 (testis) -3.34483
PCNA proliferating cell nuclear antigen -3.13266
TSPAN4 tetraspanin 4 -3.09587
SMNDC1 survival motor neuron domain containing 1 -2.92242
HSPA1A heat shock 70kDa protein 1A -2.35833
PLP2 proteolipid protein 2 (colonic epithelium-enriched) -2.24562
CDS2 CDP-diacylglycerol synthase (phosphatidate cytidylyltransferase) 2 -2.20876
FASTKD5 FAST kinase domains 5 -2.14055
CDKN1B cyclin-dependent kinase inhibitor 1B (p27, Kip1) -2.05975