CRCGN017_MCF10A.TP53.M_24H:D23 Gene Set
Genes
27 genes differentially expressed following the CRCGN017_MCF10A.TP53.M_24H:D23 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
DYRK3
|
dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3
|
4.76693
|
|
E2F2
|
E2F transcription factor 2
|
3.97136
|
|
BACE2
|
beta-site APP-cleaving enzyme 2
|
3.50764
|
|
STK10
|
serine/threonine kinase 10
|
2.73781
|
|
DENND2D
|
DENN/MADD domain containing 2D
|
2.66337
|
|
TSEN2
|
TSEN2 tRNA splicing endonuclease subunit
|
2.60985
|
|
CLNS1A
|
chloride channel, nucleotide-sensitive, 1A
|
2.57132
|
|
AAMDC
|
adipogenesis associated, Mth938 domain containing
|
2.46462
|
|
WDR37
|
WD repeat domain 37
|
2.46363
|
|
COQ8A
|
coenzyme Q8A
|
2.46122
|
|
ACAA1
|
acetyl-CoA acyltransferase 1
|
2.38974
|
|
PKN1
|
protein kinase N1
|
2.12121
|
|
STXBP1
|
syntaxin binding protein 1
|
2.01488
|
|
CXCL2
|
chemokine (C-X-C motif) ligand 2
|
2.01253
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
BASP1
|
brain abundant, membrane attached signal protein 1
|
-5.74018
|
|
MSMO1
|
methylsterol monooxygenase 1
|
-4.39133
|
|
HMGCS1
|
3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)
|
-4.22679
|
|
KRT14
|
keratin 14, type I
|
-3.77728
|
|
HMG20B
|
high mobility group 20B
|
-3.36541
|
|
GRN
|
granulin
|
-3.35164
|
|
TRAPPC3
|
trafficking protein particle complex 3
|
-2.89708
|
|
PPIC
|
peptidylprolyl isomerase C (cyclophilin C)
|
-2.85792
|
|
G3BP1
|
GTPase activating protein (SH3 domain) binding protein 1
|
-2.6168
|
|
KDM3A
|
lysine (K)-specific demethylase 3A
|
-2.60859
|
|
TYROBP
|
TYRO protein tyrosine kinase binding protein
|
-2.44337
|
|
PPP2R5E
|
protein phosphatase 2, regulatory subunit B', epsilon isoform
|
-2.16477
|
|
MRPS16
|
mitochondrial ribosomal protein S16
|
-2.06274
|
