CRCGN017_MCF10A.TP53.M_24H:D24 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description 3,3'-dimethoxybenzidine.2hcl 10.7 um perturbation at 24 h in MCF10A.TP53.M (Carcinogenome)
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Genes

21 genes differentially expressed following the CRCGN017_MCF10A.TP53.M_24H:D24 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
PLSCR1 phospholipid scramblase 1 3.62317
E2F2 E2F transcription factor 2 3.51786
SATB1 SATB homeobox 1 2.97803
CERK ceramide kinase 2.85461
ACAA1 acetyl-CoA acyltransferase 1 2.62189
TIAM1 T-cell lymphoma invasion and metastasis 1 2.44875
TSPAN6 tetraspanin 6 2.43552
RSU1 Ras suppressor protein 1 2.19306
RBP4 retinol binding protein 4, plasma 2.05126
TPD52L2 tumor protein D52-like 2 2.0115

decreased expression

Symbol Name Standardized Value
TM9SF3 transmembrane 9 superfamily member 3 -4.73919
NVL nuclear VCP-like -3.65431
KRT14 keratin 14, type I -3.61696
BAG3 BCL2-associated athanogene 3 -3.36115
PCNA proliferating cell nuclear antigen -3.3203
XPNPEP1 X-prolyl aminopeptidase (aminopeptidase P) 1, soluble -2.88588
PPP2R5E protein phosphatase 2, regulatory subunit B', epsilon isoform -2.88381
KDM3A lysine (K)-specific demethylase 3A -2.86479
DEGS1 delta(4)-desaturase, sphingolipid 1 -2.78043
BASP1 brain abundant, membrane attached signal protein 1 -2.41263
SDC1 syndecan 1 -2.30213