| Dataset | Carcinogenome Chemical Perturbation Carcinogenicity Signatures |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | tetrakis(hydroxymethyl)phosphonium sulfate 33.99 um perturbation at 24 h in MCF10A.TP53.M (Carcinogenome) |
| Similar Terms | |
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207 genes differentially expressed following the CRCGN017_MCF10A.TP53.M_24H:E02 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| TRIM13 | tripartite motif containing 13 | 5.8124 |
| ABCC5 | ATP-binding cassette, sub-family C (CFTR/MRP), member 5 | 5.7207 |
| UBQLN2 | ubiquilin 2 | 5.5352 |
| NUCB2 | nucleobindin 2 | 5.5322 |
| AGR2 | anterior gradient 2 | 5.1595 |
| CCL2 | chemokine (C-C motif) ligand 2 | 4.936 |
| USP7 | ubiquitin specific peptidase 7 (herpes virus-associated) | 4.2236 |
| TMEM186 | transmembrane protein 186 | 3.5944 |
| AKR1C3 | aldo-keto reductase family 1, member C3 | 3.38165 |
| TSPAN6 | tetraspanin 6 | 3.15455 |
| TSKU | tsukushi, small leucine rich proteoglycan | 3.154 |
| KLHDC2 | kelch domain containing 2 | 3.13265 |
| TXNL4B | thioredoxin-like 4B | 3.1 |
| ENTPD3 | ectonucleoside triphosphate diphosphohydrolase 3 | 3.06895 |
| ACAA1 | acetyl-CoA acyltransferase 1 | 3.04625 |
| GCLC | glutamate-cysteine ligase, catalytic subunit | 2.94877 |
| HBA1 | hemoglobin, alpha 1 | 2.92909 |
| ZBED5 | zinc finger, BED-type containing 5 | 2.90175 |
| ID2 | inhibitor of DNA binding 2, dominant negative helix-loop-helix protein | 2.87675 |
| CNPY3 | canopy FGF signaling regulator 3 | 2.87475 |
| WIF1 | WNT inhibitory factor 1 | 2.85235 |
| CYP4F11 | cytochrome P450, family 4, subfamily F, polypeptide 11 | 2.8061 |
| CP | ceruloplasmin (ferroxidase) | 2.73935 |
| ZNF85 | zinc finger protein 85 | 2.70115 |
| SMIM41 | small integral membrane protein 41 | 2.70015 |
| GARRE1 | granule associated Rac and RHOG effector 1 | 2.6386 |
| AKR1C1 | aldo-keto reductase family 1, member C1 | 2.63118 |
| CNRIP1 | cannabinoid receptor interacting protein 1 | 2.6197 |
| IPO13 | importin 13 | 2.59675 |
| ABCC1 | ATP-binding cassette, sub-family C (CFTR/MRP), member 1 | 2.47595 |
| EPN2 | epsin 2 | 2.46668 |
| LRRC47 | leucine rich repeat containing 47 | 2.4548 |
| EIF2AK1 | eukaryotic translation initiation factor 2-alpha kinase 1 | 2.4452 |
| DAPL1 | death associated protein-like 1 | 2.43595 |
| CAPN1 | calpain 1, (mu/I) large subunit | 2.43065 |
| SLC35C1 | solute carrier family 35 (GDP-fucose transporter), member C1 | 2.41495 |
| ALDH3A2 | aldehyde dehydrogenase 3 family, member A2 | 2.40997 |
| LRRC61 | leucine rich repeat containing 61 | 2.40715 |
| CLXN | calaxin | 2.39135 |
| ZNF195 | zinc finger protein 195 | 2.3885 |
| PACS2 | phosphofurin acidic cluster sorting protein 2 | 2.34455 |
| EPHX1 | epoxide hydrolase 1, microsomal (xenobiotic) | 2.31215 |
| POMGNT1 | protein O-linked mannose N-acetylglucosaminyltransferase 1 (beta 1,2-) | 2.3052 |
| CCR2 | chemokine (C-C motif) receptor 2 | 2.2992 |
| ADORA3 | adenosine A3 receptor | 2.28555 |
| STAP1 | signal transducing adaptor family member 1 | 2.27265 |
| GPX2 | glutathione peroxidase 2 | 2.26255 |
| EDAR | ectodysplasin A receptor | 2.25845 |
| MSMB | microseminoprotein, beta- | 2.24697 |
| METTL22 | methyltransferase like 22 | 2.24595 |
| ERI2 | ERI1 exoribonuclease family member 2 | 2.22655 |
| MRTFB | myocardin related transcription factor B | 2.22355 |
| NALF1 | NALCN channel auxiliary factor 1 | 2.21635 |
| TMEM14B | transmembrane protein 14B | 2.2043 |
| ADH7 | alcohol dehydrogenase 7 (class IV), mu or sigma polypeptide | 2.2033 |
| COL11A1 | collagen, type XI, alpha 1 | 2.18383 |
| TRIM8 | tripartite motif containing 8 | 2.1816 |
| HERC3 | HECT and RLD domain containing E3 ubiquitin protein ligase 3 | 2.1815 |
| ZKSCAN2 | zinc finger with KRAB and SCAN domains 2 | 2.1789 |
| MARCHF1 | membrane associated ring-CH-type finger 1 | 2.17485 |
| HNRNPC | heterogeneous nuclear ribonucleoprotein C (C1/C2) | 2.1713 |
| RTL10 | retrotransposon Gag like 10 | 2.16465 |
| PMM2 | phosphomannomutase 2 | 2.1539 |
| TF | transferrin | 2.14975 |
| ALDH3A1 | aldehyde dehydrogenase 3 family, member A1 | 2.1477 |
| SQSTM1 | sequestosome 1 | 2.13462 |
| HGSNAT | heparan-alpha-glucosaminide N-acetyltransferase | 2.13225 |
| PTCD1 | pentatricopeptide repeat domain 1 | 2.1285 |
| TRAPPC14 | trafficking protein particle complex subunit 14 | 2.1272 |
| TRMT61B | tRNA methyltransferase 61B | 2.12665 |
| ZNF12 | zinc finger protein 12 | 2.1115 |
| BCL2L1 | BCL2-like 1 | 2.11027 |
| LPAR6 | lysophosphatidic acid receptor 6 | 2.1065 |
| PSENEN | presenilin enhancer gamma secretase subunit | 2.1013 |
| PIGT | phosphatidylinositol glycan anchor biosynthesis, class T | 2.0974 |
| HABP2 | hyaluronan binding protein 2 | 2.08255 |
| LCK | LCK proto-oncogene, Src family tyrosine kinase | 2.08157 |
| SHC1 | SHC (Src homology 2 domain containing) transforming protein 1 | 2.08073 |
| SPSB1 | splA/ryanodine receptor domain and SOCS box containing 1 | 2.0775 |
| U2AF2 | U2 small nuclear RNA auxiliary factor 2 | 2.07665 |
| TALDO1 | transaldolase 1 | 2.07355 |
| POLR3B | polymerase (RNA) III (DNA directed) polypeptide B | 2.0724 |
| SETMAR | SET domain and mariner transposase fusion gene | 2.0652 |
| CDK5RAP1 | CDK5 regulatory subunit associated protein 1 | 2.06385 |
| TRIM39-RPP21 | TRIM39-RPP21 readthrough | 2.06195 |
| HPSE | heparanase | 2.0568 |
| ZNF668 | zinc finger protein 668 | 2.0557 |
| ASIC1 | acid sensing (proton gated) ion channel 1 | 2.0549 |
| FANCF | Fanconi anemia, complementation group F | 2.05265 |
| TBC1D30 | TBC1 domain family, member 30 | 2.05055 |
| CACNG2 | calcium channel, voltage-dependent, gamma subunit 2 | 2.0483 |
| ZDHHC13 | zinc finger, DHHC-type containing 13 | 2.0421 |
| SEPHS2 | selenophosphate synthetase 2 | 2.04175 |
| OSGIN1 | oxidative stress induced growth inhibitor 1 | 2.04005 |
| ABHD14A | abhydrolase domain containing 14A | 2.0391 |
| ERMAP | erythroblast membrane-associated protein (Scianna blood group) | 2.035 |
| RASGRP1 | RAS guanyl releasing protein 1 (calcium and DAG-regulated) | 2.0334 |
| GHR | growth hormone receptor | 2.03215 |
| LYRM1 | LYR motif containing 1 | 2.03055 |
| PRSS8 | protease, serine, 8 | 2.0295 |
| BCL11A | B-cell CLL/lymphoma 11A (zinc finger protein) | 2.0287 |
| TTC9 | tetratricopeptide repeat domain 9 | 2.01605 |
| CFI | complement factor I | 2.0153 |
| MRPS18A | mitochondrial ribosomal protein S18A | 2.00335 |
| STYXL1 | serine/threonine/tyrosine interacting-like 1 | 2.001 |
| Symbol | Name | Standardized Value |
|---|---|---|
| KIF14 | kinesin family member 14 | -6.13585 |
| ACOT9 | acyl-CoA thioesterase 9 | -5.30535 |
| KRT14 | keratin 14, type I | -5.1895 |
| HMG20B | high mobility group 20B | -5.0762 |
| UFM1 | ubiquitin-fold modifier 1 | -5.02485 |
| ATP11B | ATPase, class VI, type 11B | -4.8822 |
| VDAC1 | voltage-dependent anion channel 1 | -4.79505 |
| JMJD6 | jumonji domain containing 6 | -4.48772 |
| KDM3A | lysine (K)-specific demethylase 3A | -4.23235 |
| BID | BH3 interacting domain death agonist | -4.01998 |
| G3BP1 | GTPase activating protein (SH3 domain) binding protein 1 | -3.73945 |
| PRELID3B | PRELI domain containing 3B | -3.4661 |
| PDHA1 | pyruvate dehydrogenase (lipoamide) alpha 1 | -3.09385 |
| TPK1 | thiamin pyrophosphokinase 1 | -3.0702 |
| UQCR10 | ubiquinol-cytochrome c reductase, complex III subunit X | -3.0261 |
| EXOSC8 | exosome component 8 | -2.9636 |
| UPF2 | UPF2 regulator of nonsense transcripts homolog (yeast) | -2.9455 |
| SMN2 | survival of motor neuron 2, centromeric | -2.9395 |
| SDHB | succinate dehydrogenase complex, subunit B, iron sulfur (Ip) | -2.84415 |
| MSMO1 | methylsterol monooxygenase 1 | -2.80995 |
| SCML2 | sex comb on midleg-like 2 (Drosophila) | -2.8054 |
| AHCTF1 | AT hook containing transcription factor 1 | -2.76155 |
| NUDT19 | nudix (nucleoside diphosphate linked moiety X)-type motif 19 | -2.6979 |
| MSN | moesin | -2.66425 |
| SAP30BP | SAP30 binding protein | -2.6567 |
| APOO | apolipoprotein O | -2.56225 |
| USPL1 | ubiquitin specific peptidase like 1 | -2.52525 |
| SCML1 | sex comb on midleg-like 1 (Drosophila) | -2.49315 |
| PRDX4 | peroxiredoxin 4 | -2.4931 |
| DEPDC1 | DEP domain containing 1 | -2.4754 |
| PRKAR1A | protein kinase, cAMP-dependent, regulatory, type I, alpha | -2.45873 |
| KIF18A | kinesin family member 18A | -2.4497 |
| HOXB9 | homeobox B9 | -2.44935 |
| MXRA7 | matrix-remodelling associated 7 | -2.4264 |
| NAA16 | N(alpha)-acetyltransferase 16, NatA auxiliary subunit | -2.41235 |
| USP39 | ubiquitin specific peptidase 39 | -2.4058 |
| DCP2 | decapping mRNA 2 | -2.4051 |
| CLCC1 | chloride channel CLIC-like 1 | -2.3906 |
| HOMER1 | homer scaffolding protein 1 | -2.3802 |
| RBM23 | RNA binding motif protein 23 | -2.3684 |
| CKAP2 | cytoskeleton associated protein 2 | -2.3392 |
| MAT2B | methionine adenosyltransferase II, beta | -2.32465 |
| ASPM | asp (abnormal spindle) homolog, microcephaly associated (Drosophila) | -2.3198 |
| SKA1 | spindle and kinetochore associated complex subunit 1 | -2.3196 |
| POLR3D | polymerase (RNA) III (DNA directed) polypeptide D, 44kDa | -2.3166 |
| PTTG1 | pituitary tumor-transforming 1 | -2.3156 |
| AURKA | aurora kinase A | -2.29023 |
| PER1 | period circadian clock 1 | -2.28482 |
| BCL10 | B-cell CLL/lymphoma 10 | -2.28245 |
| ING1 | inhibitor of growth family, member 1 | -2.26543 |
| GMCL1 | germ cell-less, spermatogenesis associated 1 | -2.25485 |
| TUBGCP3 | tubulin, gamma complex associated protein 3 | -2.2535 |
| FER | fer (fps/fes related) tyrosine kinase | -2.2518 |
| GNG5 | guanine nucleotide binding protein (G protein), gamma 5 | -2.23675 |
| ATP5PD | ATP synthase peripheral stalk subunit d | -2.23235 |
| MEX3C | mex-3 RNA binding family member C | -2.21785 |
| FFAR2 | free fatty acid receptor 2 | -2.19835 |
| UCHL5 | ubiquitin carboxyl-terminal hydrolase L5 | -2.19785 |
| LOC102724594 | splicing factor U2AF 35 kDa subunit | -2.1964 |
| CAVIN3 | caveolae associated protein 3 | -2.1539 |
| CDC25B | cell division cycle 25B | -2.1498 |
| TAF1A | TATA box binding protein (TBP)-associated factor, RNA polymerase I, A, 48kDa | -2.14615 |
| SHCBP1 | SHC SH2-domain binding protein 1 | -2.14515 |
| KIF20A | kinesin family member 20A | -2.1449 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -2.1354 |
| SNAPC1 | small nuclear RNA activating complex, polypeptide 1, 43kDa | -2.13405 |
| TMEM38B | transmembrane protein 38B | -2.1323 |
| SEC61B | Sec61 beta subunit | -2.12965 |
| SPAG5 | sperm associated antigen 5 | -2.12685 |
| COLGALT1 | collagen beta(1-O)galactosyltransferase 1 | -2.1264 |
| TEX30 | testis expressed 30 | -2.11425 |
| PFDN2 | prefoldin subunit 2 | -2.11035 |
| CIAPIN1 | cytokine induced apoptosis inhibitor 1 | -2.10827 |
| DIS3 | DIS3 exosome endoribonuclease and 3'-5' exoribonuclease | -2.1074 |
| COL4A2 | collagen, type IV, alpha 2 | -2.10425 |
| HMMR | hyaluronan-mediated motility receptor (RHAMM) | -2.10308 |
| ZEB2 | zinc finger E-box binding homeobox 2 | -2.08775 |
| CDK1 | cyclin-dependent kinase 1 | -2.08677 |
| S100A7 | S100 calcium binding protein A7 | -2.07905 |
| CEP63 | centrosomal protein 63kDa | -2.0766 |
| CLINT1 | clathrin interactor 1 | -2.07107 |
| FAM216A | family with sequence similarity 216, member A | -2.06585 |
| EGR3 | early growth response 3 | -2.0631 |
| FKTN | fukutin | -2.0568 |
| HLTF | helicase-like transcription factor | -2.0483 |
| IL24 | interleukin 24 | -2.0449 |
| PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | -2.04385 |
| SLC25A24 | solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 24 | -2.03485 |
| HOXC6 | homeobox C6 | -2.02715 |
| MIS18BP1 | MIS18 binding protein 1 | -2.0251 |
| NT5DC2 | 5'-nucleotidase domain containing 2 | -2.0222 |
| BNIP2 | BCL2/adenovirus E1B 19kDa interacting protein 2 | -2.02165 |
| AK4 | adenylate kinase 4 | -2.02065 |
| MIA | melanoma inhibitory activity | -2.01865 |
| STX11 | syntaxin 11 | -2.0162 |
| EZH2 | enhancer of zeste 2 polycomb repressive complex 2 subunit | -2.0142 |
| AKAP17A | A kinase (PRKA) anchor protein 17A | -2.0084 |
| DDX10 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 10 | -2.00765 |
| CHSY1 | chondroitin sulfate synthase 1 | -2.00395 |
| NCK2 | NCK adaptor protein 2 | -2.00345 |
| HMG20A | high mobility group 20A | -2.00265 |
| COQ10B | coenzyme Q10 homolog B (S. cerevisiae) | -2.0018 |
