CRCGN017_MCF10A.TP53.M_24H:E08 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description rotenone 33.99 um perturbation at 24 h in MCF10A.TP53.M (Carcinogenome)
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Genes

1006 genes differentially expressed following the CRCGN017_MCF10A.TP53.M_24H:E08 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
CCDC92 coiled-coil domain containing 92 7.18065
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) 7.1141
CHIC2 cysteine-rich hydrophobic domain 2 7.08723
MSRA methionine sulfoxide reductase A 6.93894
TNIP1 TNFAIP3 interacting protein 1 6.13552
TICAM1 toll-like receptor adaptor molecule 1 5.87879
WIF1 WNT inhibitory factor 1 5.62011
TP53BP2 tumor protein p53 binding protein 2 5.50078
USP6NL USP6 N-terminal like 5.2777
STK10 serine/threonine kinase 10 4.8773
ST6GALNAC2 ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2 4.79608
IL1B interleukin 1, beta 4.573
RGS2 regulator of G-protein signaling 2 4.56958
FGFR4 fibroblast growth factor receptor 4 4.40589
GLRX glutaredoxin (thioltransferase) 4.31751
STXBP1 syntaxin binding protein 1 4.31359
DUSP14 dual specificity phosphatase 14 4.19817
TIMP2 TIMP metallopeptidase inhibitor 2 4.15402
SLC75A1 solute carrier family 75 member 1 4.13887
MYH9 myosin, heavy chain 9, non-muscle 4.10476
CXCL2 chemokine (C-X-C motif) ligand 2 4.0826
AGR2 anterior gradient 2 4.03909
TMEM40 transmembrane protein 40 4.00662
DDX42 DEAD (Asp-Glu-Ala-Asp) box helicase 42 3.98744
NCK2 NCK adaptor protein 2 3.91598
CNIH4 cornichon family AMPA receptor auxiliary protein 4 3.90476
HMOX1 heme oxygenase 1 3.89082
RBP4 retinol binding protein 4, plasma 3.83869
SQOR sulfide quinone oxidoreductase 3.8089
DDA1 DET1 and DDB1 associated 1 3.71492
CARS1 cysteinyl-tRNA synthetase 1 3.6567
CAB39L calcium binding protein 39-like 3.5972
AARS1 alanyl-tRNA synthetase 1 3.59532
GARS1 glycyl-tRNA synthetase 1 3.58025
ALAS1 5'-aminolevulinate synthase 1 3.56095
TMBIM1 transmembrane BAX inhibitor motif containing 1 3.542
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 3.52696
PCK2 phosphoenolpyruvate carboxykinase 2 (mitochondrial) 3.5109
CHAC1 ChaC glutathione-specific gamma-glutamylcyclotransferase 1 3.4841
IL1A interleukin 1, alpha 3.47659
MACO1 macoilin 1 3.47542
GSTZ1 glutathione S-transferase zeta 1 3.47347
OXSR1 oxidative stress responsive 1 3.46727
COMP cartilage oligomeric matrix protein 3.46504
MINDY1 MINDY lysine 48 deubiquitinase 1 3.45951
COL17A1 collagen, type XVII, alpha 1 3.42087
TBXA2R thromboxane A2 receptor 3.41617
PMAIP1 phorbol-12-myristate-13-acetate-induced protein 1 3.38839
SARS1 seryl-tRNA synthetase 1 3.38648
EHD1 EH-domain containing 1 3.36774
OTUB2 OTU deubiquitinase, ubiquitin aldehyde binding 2 3.34256
ZNF804A zinc finger protein 804A 3.30436
SERPINB7 serpin peptidase inhibitor, clade B (ovalbumin), member 7 3.30242
QSOX1 quiescin Q6 sulfhydryl oxidase 1 3.27646
SLC2A1 solute carrier family 2 (facilitated glucose transporter), member 1 3.23782
TXNRD1 thioredoxin reductase 1 3.21781
PTPN1 protein tyrosine phosphatase, non-receptor type 1 3.199
GRB7 growth factor receptor-bound protein 7 3.19822
SLC2A6 solute carrier family 2 (facilitated glucose transporter), member 6 3.17612
KLC3 kinesin light chain 3 3.15403
TRIB3 tribbles pseudokinase 3 3.15257
RFTN1 raftlin, lipid raft linker 1 3.13522
SLC6A9 solute carrier family 6 (neurotransmitter transporter, glycine), member 9 3.134
LRP10 low density lipoprotein receptor-related protein 10 3.11845
RELB v-rel avian reticuloendotheliosis viral oncogene homolog B 3.11504
PPP2R5B protein phosphatase 2, regulatory subunit B', beta 3.10624
KCNK1 potassium channel, two pore domain subfamily K, member 1 3.10395
YARS1 tyrosyl-tRNA synthetase 1 3.08234
G0S2 G0/G1 switch 2 3.07364
LAMB3 laminin, beta 3 3.07362
ATOSB atos homolog B 3.06567
PGAP6 post-GPI attachment to proteins 6 3.05859
NPDC1 neural proliferation, differentiation and control, 1 3.04339
ERVMER34-1 endogenous retrovirus group MER34, member 1 3.03501
SOX4 SRY (sex determining region Y)-box 4 3.03412
MARCHF2 membrane associated ring-CH-type finger 2 3.0301
RAI14 retinoic acid induced 14 3.02895
CRCT1 cysteine-rich C-terminal 1 3.02638
PRSS3 protease, serine, 3 3.01696
MAP1LC3B microtubule-associated protein 1 light chain 3 beta 3.01597
EFHD1 EF-hand domain family, member D1 3.00998
POF1B premature ovarian failure, 1B 2.98964
CDPF1 cysteine-rich, DPF motif domain containing 1 2.98417
CXCL3 chemokine (C-X-C motif) ligand 3 2.98211
CEMIP2 cell migration inducing hyaluronidase 2 2.97857
MYL9 myosin, light chain 9, regulatory 2.97716
ALOXE3 arachidonate lipoxygenase 3 2.96813
IBSP integrin-binding sialoprotein 2.94984
VAT1 vesicle amine transport 1 2.94306
PRRG1 proline rich Gla (G-carboxyglutamic acid) 1 2.93808
LCE2B late cornified envelope 2B 2.93041
ITGA2 integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) 2.93034
WDR45B WD repeat domain 45B 2.92779
IL36RN interleukin 36 receptor antagonist 2.92082
KRT9 keratin 9, type I 2.91031
PYCR1 pyrroline-5-carboxylate reductase 1 2.9079
AVEN apoptosis, caspase activation inhibitor 2.90471
WASHC5 WASH complex subunit 5 2.899
ELOVL1 ELOVL fatty acid elongase 1 2.89218
INSIG2 insulin induced gene 2 2.88345
KRT34 keratin 34, type I 2.88309
LAMC2 laminin, gamma 2 2.8796
KRT23 keratin 23, type I 2.87898
NT5E 5'-nucleotidase, ecto (CD73) 2.87838
METTL22 methyltransferase like 22 2.85199
DYNC1I2 dynein, cytoplasmic 1, intermediate chain 2 2.85072
CWH43 cell wall biogenesis 43 C-terminal homolog (S. cerevisiae) 2.84238
TCIRG1 T-cell, immune regulator 1, ATPase, H+ transporting, lysosomal V0 subunit A3 2.83995
PCGF3 polycomb group ring finger 3 2.83432
ATF4 activating transcription factor 4 2.83065
PSEN2 presenilin 2 2.82959
PLOD3 procollagen-lysine, 2-oxoglutarate 5-dioxygenase 3 2.82847
CAB39 calcium binding protein 39 2.82725
OLAH oleoyl-ACP hydrolase 2.82082
CRELD2 cysteine-rich with EGF-like domains 2 2.81482
DKK3 dickkopf WNT signaling pathway inhibitor 3 2.80385
RAP1GAP RAP1 GTPase activating protein 2.78914
LOC102724428 serine/threonine-protein kinase SIK1 2.7855
FBXO28 F-box protein 28 2.7738
POLD4 polymerase (DNA-directed), delta 4, accessory subunit 2.76713
ITFG1 integrin alpha FG-GAP repeat containing 1 2.76699
PPARG peroxisome proliferator-activated receptor gamma 2.76318
SAMD14 sterile alpha motif domain containing 14 2.75954
GDI1 GDP dissociation inhibitor 1 2.75766
GBE1 glucan (1,4-alpha-), branching enzyme 1 2.75083
TNFAIP1 tumor necrosis factor, alpha-induced protein 1 (endothelial) 2.74697
BSDC1 BSD domain containing 1 2.74248
ANXA9 annexin A9 2.73915
IL23A interleukin 23, alpha subunit p19 2.73795
ELF5 E74-like factor 5 (ets domain transcription factor) 2.73277
ISG20 interferon stimulated exonuclease gene 20kDa 2.72898
EPPK1 epiplakin 1 2.72092
P4HA1 prolyl 4-hydroxylase, alpha polypeptide I 2.71344
FYN FYN proto-oncogene, Src family tyrosine kinase 2.71335
P2RX3 purinergic receptor P2X, ligand gated ion channel, 3 2.71167
SP100 SP100 nuclear antigen 2.68432
RPS6KA6 ribosomal protein S6 kinase, 90kDa, polypeptide 6 2.67971
VPS37C vacuolar protein sorting 37 homolog C (S. cerevisiae) 2.67613
LOC102724560 cystathionine beta-synthase 2.67449
CDSN corneodesmosin 2.66853
NPC1 Niemann-Pick disease, type C1 2.66666
ASAP2 ArfGAP with SH3 domain, ankyrin repeat and PH domain 2 2.66641
SLC30A1 solute carrier family 30 (zinc transporter), member 1 2.66427
ISG15 ISG15 ubiquitin-like modifier 2.66354
SPINT1 serine peptidase inhibitor, Kunitz type 1 2.66221
CTIF CBP80/20-dependent translation initiation factor 2.6536
STAP2 signal transducing adaptor family member 2 2.65228
DNASE1L1 deoxyribonuclease I-like 1 2.6515
CEBPE CCAAT/enhancer binding protein (C/EBP), epsilon 2.64243
MTHFD2 methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase 2.64123
PLD2 phospholipase D2 2.62745
CDR2L cerebellar degeneration-related protein 2-like 2.62709
SUPV3L1 suppressor of var1, 3-like 1 (S. cerevisiae) 2.62387
RHBDF1 rhomboid 5 homolog 1 (Drosophila) 2.61916
MGRN1 mahogunin ring finger 1, E3 ubiquitin protein ligase 2.61835
PSORS1C2 psoriasis susceptibility 1 candidate 2 2.61222
FILIP1L filamin A interacting protein 1-like 2.61104
DCTN1 dynactin 1 2.61034
PIEZO1 piezo-type mechanosensitive ion channel component 1 2.60979
GATA3 GATA binding protein 3 2.60797
PLEKHS1 pleckstrin homology domain containing, family S member 1 2.59874
DHX32 DEAH (Asp-Glu-Ala-His) box polypeptide 32 2.59514
MINPP1 multiple inositol-polyphosphate phosphatase 1 2.59392
FETUB fetuin B 2.59351
MMP24OS MMP24 opposite strand 2.58832
DNAJB2 DnaJ (Hsp40) homolog, subfamily B, member 2 2.58831
ACOX1 acyl-CoA oxidase 1, palmitoyl 2.5816
RALA v-ral simian leukemia viral oncogene homolog A (ras related) 2.58124
ULBP2 UL16 binding protein 2 2.57783
DRAM1 DNA-damage regulated autophagy modulator 1 2.57761
GTPBP2 GTP binding protein 2 2.5654
CA6 carbonic anhydrase VI 2.55297
EPS8L2 EPS8-like 2 2.54415
RHBDF2 rhomboid 5 homolog 2 (Drosophila) 2.54216
ARHGAP29 Rho GTPase activating protein 29 2.54104
OPTN optineurin 2.53939
INF2 inverted formin, FH2 and WH2 domain containing 2.53005
CYB5R2 cytochrome b5 reductase 2 2.52938
GPR161 G protein-coupled receptor 161 2.52309
STX12 syntaxin 12 2.52147
CYP2C18 cytochrome P450, family 2, subfamily C, polypeptide 18 2.52117
CACNB3 calcium channel, voltage-dependent, beta 3 subunit 2.51942
ASNS asparagine synthetase (glutamine-hydrolyzing) 2.51139
PKP1 plakophilin 1 2.49654
CAP1 CAP, adenylate cyclase-associated protein 1 (yeast) 2.49121
RNF39 ring finger protein 39 2.49117
PSG7 pregnancy specific beta-1-glycoprotein 7 (gene/pseudogene) 2.49068
TPM1 tropomyosin 1 (alpha) 2.48933
ARSL arylsulfatase L 2.48927
COL9A3 collagen, type IX, alpha 3 2.48859
GRAMD2B GRAM domain containing 2B 2.48403
RASL11B RAS-like, family 11, member B 2.47378
TAL1 T-cell acute lymphocytic leukemia 1 2.47198
ANTKMT adenine nucleotide translocase lysine methyltransferase 2.46875
TMEM184B transmembrane protein 184B 2.46724
EDN1 endothelin 1 2.4666
MTSS1 metastasis suppressor 1 2.4656
F7 coagulation factor VII (serum prothrombin conversion accelerator) 2.46158
PIGU phosphatidylinositol glycan anchor biosynthesis, class U 2.45209
STX4 syntaxin 4 2.45134
GBX2 gastrulation brain homeobox 2 2.4491
ARHGAP8 Rho GTPase activating protein 8 2.44708
RTN4 reticulon 4 2.44188
WNT7A wingless-type MMTV integration site family, member 7A 2.43535
PLEK2 pleckstrin 2 2.43506
AMOTL2 angiomotin like 2 2.43409
CTSZ cathepsin Z 2.43284
TRIM8 tripartite motif containing 8 2.43045
GPR27 G protein-coupled receptor 27 2.42835
WARS1 tryptophanyl-tRNA synthetase 1 2.42694
OSBPL2 oxysterol binding protein-like 2 2.42678
SRP14 signal recognition particle 14kDa (homologous Alu RNA binding protein) 2.42641
PLA2G4A phospholipase A2, group IVA (cytosolic, calcium-dependent) 2.4244
COL9A2 collagen, type IX, alpha 2 2.42182
SERPINB8 serpin peptidase inhibitor, clade B (ovalbumin), member 8 2.4211
MBOAT2 membrane bound O-acyltransferase domain containing 2 2.41884
DYNLT1 dynein, light chain, Tctex-type 1 2.41865
H2BC12 H2B clustered histone 12 2.41788
HBEGF heparin-binding EGF-like growth factor 2.40423
ADIRF adipogenesis regulatory factor 2.39881
PGLYRP4 peptidoglycan recognition protein 4 2.39608
TERF2IP telomeric repeat binding factor 2, interacting protein 2.39498
PTPN21 protein tyrosine phosphatase, non-receptor type 21 2.39367
DCTN6 dynactin 6 2.38711
KLF3 Kruppel-like factor 3 (basic) 2.38372
ARHGEF2 Rho/Rac guanine nucleotide exchange factor (GEF) 2 2.38119
IER3 immediate early response 3 2.37723
TNIP2 TNFAIP3 interacting protein 2 2.37396
CDA cytidine deaminase 2.36966
MAPK7 mitogen-activated protein kinase 7 2.36606
CHST15 carbohydrate (N-acetylgalactosamine 4-sulfate 6-O) sulfotransferase 15 2.36181
IL15RA interleukin 15 receptor, alpha 2.36142
CNTN1 contactin 1 2.36049
BNIP3L BCL2/adenovirus E1B 19kDa interacting protein 3-like 2.3603
LMTK1 lemur tail kinase 1 2.35656
SH3TC2 SH3 domain and tetratricopeptide repeats 2 2.35632
MYO6 myosin VI 2.35519
LIN7A lin-7 homolog A (C. elegans) 2.35512
SMIM40 small integral membrane protein 40 2.35389
SFT2D2 SFT2 domain containing 2 2.35318
IFNGR2 interferon gamma receptor 2 (interferon gamma transducer 1) 2.3529
MTCL1 microtubule crosslinking factor 1 2.3509
MINDY3 MINDY lysine 48 deubiquitinase 3 2.34601
POLH polymerase (DNA directed), eta 2.34502
ELMO1 engulfment and cell motility 1 2.34082
ELL3 elongation factor RNA polymerase II-like 3 2.33552
PPOX protoporphyrinogen oxidase 2.32907
DDX19B DEAD (Asp-Glu-Ala-Asp) box polypeptide 19B 2.32672
IDE insulin-degrading enzyme 2.31967
FGF3 fibroblast growth factor 3 2.31909
ARID4B AT rich interactive domain 4B (RBP1-like) 2.31671
CCN2 cellular communication network factor 2 2.31602
AIFM2 apoptosis-inducing factor, mitochondrion-associated, 2 2.31546
PSG5 pregnancy specific beta-1-glycoprotein 5 2.3147
EZR ezrin 2.31323
MAP2K1 mitogen-activated protein kinase kinase 1 2.31194
ABCA12 ATP-binding cassette, sub-family A (ABC1), member 12 2.31123
LGALS4 lectin, galactoside-binding, soluble, 4 2.31019
EIF2S3 eukaryotic translation initiation factor 2, subunit 3 gamma, 52kDa 2.30912
WIPI1 WD repeat domain, phosphoinositide interacting 1 2.30534
RPS6KA2 ribosomal protein S6 kinase, 90kDa, polypeptide 2 2.30384
APOBEC3F apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3F 2.30053
CLIC3 chloride intracellular channel 3 2.29972
ENDOU endonuclease, polyU-specific 2.29888
DOK7 docking protein 7 2.2981
UBTD1 ubiquitin domain containing 1 2.2975
USP15 ubiquitin specific peptidase 15 2.29598
P3H1 prolyl 3-hydroxylase 1 2.29572
DIPK1A divergent protein kinase domain 1A 2.29535
PLS1 plastin 1 2.29514
CYP2C19 cytochrome P450, family 2, subfamily C, polypeptide 19 2.29239
AGPAT2 1-acylglycerol-3-phosphate O-acyltransferase 2 2.2888
BMPR2 bone morphogenetic protein receptor, type II (serine/threonine kinase) 2.28601
ITSN2 intersectin 2 2.28186
RGS20 regulator of G-protein signaling 20 2.27953
KLK5 kallikrein-related peptidase 5 2.27655
CRIPTO3 cripto, EGF-CFC family member 3 2.2753
MMP9 matrix metallopeptidase 9 2.27461
H1-2 H1.2 linker histone, cluster member 2.26574
JADE3 jade family PHD finger 3 2.26169
MVP major vault protein 2.26115
WBP1L WW domain binding protein 1-like 2.25987
AZU1 azurocidin 1 2.25861
MICALL1 MICAL-like 1 2.25744
LOC107985101 uncharacterized LOC107985101 2.25154
MS4A3 membrane-spanning 4-domains, subfamily A, member 3 (hematopoietic cell-specific) 2.25141
PPARD peroxisome proliferator-activated receptor delta 2.25096
TMEM94 transmembrane protein 94 2.24903
GGTLC1 gamma-glutamyltransferase light chain 1 2.24902
SLC12A4 solute carrier family 12 (potassium/chloride transporter), member 4 2.24896
MICAL1 microtubule associated monooxygenase, calponin and LIM domain containing 1 2.24659
MEAK7 MTOR associated protein, eak-7 homolog 2.24561
ITPRID2 ITPR interacting domain containing 2 2.24431
GRIN2C glutamate receptor, ionotropic, N-methyl D-aspartate 2C 2.2425
ARHGEF4 Rho guanine nucleotide exchange factor (GEF) 4 2.24108
WBP2 WW domain binding protein 2 2.24043
S100P S100 calcium binding protein P 2.23694
ULBP1 UL16 binding protein 1 2.23615
PSEN1 presenilin 1 2.23465
MARCHF3 membrane associated ring-CH-type finger 3 2.23383
CORO1A coronin, actin binding protein, 1A 2.23123
MEP1A meprin A, alpha (PABA peptide hydrolase) 2.23024
H2BC9 H2B clustered histone 9 2.22996
MOSPD1 motile sperm domain containing 1 2.22848
SLC1A4 solute carrier family 1 (glutamate/neutral amino acid transporter), member 4 2.22667
ACBD3 acyl-CoA binding domain containing 3 2.22097
KRT3 keratin 3, type II 2.22031
INHBA inhibin, beta A 2.21864
BIRC7 baculoviral IAP repeat containing 7 2.21693
KLK1 kallikrein 1 2.21588
KCMF1 potassium channel modulatory factor 1 2.21566
MOGAT3 monoacylglycerol O-acyltransferase 3 2.21101
RTCA RNA 3'-terminal phosphate cyclase 2.20838
PDZD8 PDZ domain containing 8 2.20254
ACTR3 ARP3 actin-related protein 3 homolog (yeast) 2.20229
CDCP1 CUB domain containing protein 1 2.20227
RTN2 reticulon 2 2.20098
RNASE2 ribonuclease, RNase A family, 2 (liver, eosinophil-derived neurotoxin) 2.20025
ITPKB inositol-trisphosphate 3-kinase B 2.19864
PHF7 PHD finger protein 7 2.19853
XPNPEP1 X-prolyl aminopeptidase (aminopeptidase P) 1, soluble 2.19848
WDR44 WD repeat domain 44 2.19824
TFAP2A transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha) 2.19747
IFRD1 interferon-related developmental regulator 1 2.19548
BCL2L2 BCL2-like 2 2.19417
PELI1 pellino E3 ubiquitin protein ligase 1 2.19406
FGF4 fibroblast growth factor 4 2.19274
KLF1 Kruppel-like factor 1 (erythroid) 2.18715
PZP pregnancy-zone protein 2.18323
HYAL4 hyaluronoglucosaminidase 4 2.18241
H2BC4 H2B clustered histone 4 2.18206
PLPPR3 phospholipid phosphatase related 3 2.18141
TPST2 tyrosylprotein sulfotransferase 2 2.17859
RAB40C RAB40C, member RAS oncogene family 2.17851
FGF20 fibroblast growth factor 20 2.17792
TGFB1I1 transforming growth factor beta 1 induced transcript 1 2.17692
MBD1 methyl-CpG binding domain protein 1 2.17178
OR2H1 olfactory receptor, family 2, subfamily H, member 1 2.17123
HMGA1 high mobility group AT-hook 1 2.16911
CNGA1 cyclic nucleotide gated channel alpha 1 2.16834
IFT54 intraflagellar transport 54 2.1677
DOC2B double C2-like domains, beta 2.16646
CSNK1G3 casein kinase 1, gamma 3 2.16536
ARID5B AT rich interactive domain 5B (MRF1-like) 2.16303
GABRD gamma-aminobutyric acid (GABA) A receptor, delta 2.16269
PMP22 peripheral myelin protein 22 2.16051
MLLT11 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11 2.15728
RAP1B RAP1B, member of RAS oncogene family 2.15575
MT1F metallothionein 1F 2.15516
PDGFB platelet-derived growth factor beta polypeptide 2.15132
PRR13 proline rich 13 2.14962
NADSYN1 NAD synthetase 1 2.14948
SMAP1 small ArfGAP 1 2.1492
NOL7 nucleolar protein 7, 27kDa 2.14863
GPC1 glypican 1 2.14832
NUP58 nucleoporin 58 2.14709
SEMA3C sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C 2.14707
RC3H2 ring finger and CCCH-type domains 2 2.14658
IL22RA1 interleukin 22 receptor, alpha 1 2.14651
RUNDC3A RUN domain containing 3A 2.14473
SMURF1 SMAD specific E3 ubiquitin protein ligase 1 2.14454
MAPK3 mitogen-activated protein kinase 3 2.14238
DBN1 drebrin 1 2.14123
RBM41 RNA binding motif protein 41 2.13972
RGCC regulator of cell cycle 2.13969
FHL2 four and a half LIM domains 2 2.13873
PPP1R26 protein phosphatase 1, regulatory subunit 26 2.13786
SERF2 small EDRK-rich factor 2 2.13633
VGLL4 vestigial-like family member 4 2.13556
F11R F11 receptor 2.13399
CYB5R1 cytochrome b5 reductase 1 2.13011
SLC5A1 solute carrier family 5 (sodium/glucose cotransporter), member 1 2.12891
CDC42EP1 CDC42 effector protein (Rho GTPase binding) 1 2.12727
GNB1 guanine nucleotide binding protein (G protein), beta polypeptide 1 2.12649
H2AC19 H2A clustered histone 19 2.12577
DEFA4 defensin, alpha 4, corticostatin 2.1245
RASGRP3 RAS guanyl releasing protein 3 (calcium and DAG-regulated) 2.12419
SYNRG synergin, gamma 2.12328
NDEL1 nudE neurodevelopment protein 1-like 1 2.12289
MACF1 microtubule-actin crosslinking factor 1 2.12216
MAFG v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog G 2.11927
CEACAM6 carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen) 2.11703
PRDM4 PR domain containing 4 2.11558
PRTN3 proteinase 3 2.11071
SPAG8 sperm associated antigen 8 2.1062
PSG2 pregnancy specific beta-1-glycoprotein 2 2.10553
NACAD NAC alpha domain containing 2.10423
TGFA transforming growth factor, alpha 2.10285
LRRC59 leucine rich repeat containing 59 2.10249
KAT2B K(lysine) acetyltransferase 2B 2.10168
CYP39A1 cytochrome P450, family 39, subfamily A, polypeptide 1 2.10071
ATF3 activating transcription factor 3 2.0971
CSNK1E casein kinase 1, epsilon 2.09649
CTSV cathepsin V 2.09413
TMEM59 transmembrane protein 59 2.09394
MYL6 myosin, light chain 6, alkali, smooth muscle and non-muscle 2.09
EPS8L1 EPS8-like 1 2.08868
PSMC5 proteasome (prosome, macropain) 26S subunit, ATPase, 5 2.08811
STX7 syntaxin 7 2.08745
MT1G metallothionein 1G 2.08687
CLDND1 claudin domain containing 1 2.08477
SPTA1 spectrin, alpha, erythrocytic 1 2.08464
CTC1 CTS telomere maintenance complex component 1 2.0845
LUZP2 leucine zipper protein 2 2.08247
YIPF6 Yip1 domain family, member 6 2.08144
TESK1 testis-specific kinase 1 2.07939
SH2B3 SH2B adaptor protein 3 2.07924
NSDHL NAD(P) dependent steroid dehydrogenase-like 2.07915
FKBP1B FK506 binding protein 1B, 12.6 kDa 2.07819
CST5 cystatin D 2.07747
LY6G6F-LY6G6D LY6G6F-LY6G6D readthrough 2.07072
HAND1 heart and neural crest derivatives expressed 1 2.06977
RIPOR1 RHO family interacting cell polarization regulator 1 2.06961
TBC1D9 TBC1 domain family, member 9 (with GRAM domain) 2.06872
BAMBI BMP and activin membrane-bound inhibitor 2.06759
LOC100652777 group 10 secretory phospholipase A2-like 2.06735
TMEM53 transmembrane protein 53 2.0669
NIT1 nitrilase 1 2.06655
OSBPL10 oxysterol binding protein-like 10 2.0664
ZNF821 zinc finger protein 821 2.06353
GABPB1 GA binding protein transcription factor, beta subunit 1 2.06194
CLDN17 claudin 17 2.06124
MBD5 methyl-CpG binding domain protein 5 2.06074
NR1I3 nuclear receptor subfamily 1, group I, member 3 2.06058
SCRN3 secernin 3 2.05404
PFKFB3 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3 2.05144
RUSC2 RUN and SH3 domain containing 2 2.05134
SLCO4A1 solute carrier organic anion transporter family, member 4A1 2.05039
SIRT7 sirtuin 7 2.04989
CPLANE2 ciliogenesis and planar polarity effector complex subunit 2 2.04926
CD55 CD55 molecule, decay accelerating factor for complement (Cromer blood group) 2.04876
TRIM49D2 tripartite motif containing 49D2 2.04739
AMIGO2 adhesion molecule with Ig-like domain 2 2.04628
DENND1B DENN/MADD domain containing 1B 2.04547
SERPINI2 serpin peptidase inhibitor, clade I (pancpin), member 2 2.04444
BAG6 BCL2-associated athanogene 6 2.04225
RHCE Rh blood group, CcEe antigens 2.04192
VEGFC vascular endothelial growth factor C 2.04051
DDX41 DEAD (Asp-Glu-Ala-Asp) box polypeptide 41 2.04046
TBX3 T-box 3 2.04034
JMJD7 jumonji domain containing 7 2.04021
PIK3CA phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha 2.03949
DBNDD1 dysbindin (dystrobrevin binding protein 1) domain containing 1 2.03916
TUFT1 tuftelin 1 2.03769
KCNH2 potassium channel, voltage gated eag related subfamily H, member 2 2.03692
NOMO3 NODAL modulator 3 2.03689
TINAGL1 tubulointerstitial nephritis antigen-like 1 2.03403
BCORL1 BCL6 corepressor-like 1 2.03391
ROGDI rogdi homolog (Drosophila) 2.03362
TNFSF15 tumor necrosis factor (ligand) superfamily, member 15 2.03242
CTSE cathepsin E 2.03142
TES testin LIM domain protein 2.029
ATP6V0A4 ATPase, H+ transporting, lysosomal V0 subunit a4 2.02879
GNL1 guanine nucleotide binding protein-like 1 2.02802
CYP2J2 cytochrome P450, family 2, subfamily J, polypeptide 2 2.02675
ZC2HC1C zinc finger, C2HC-type containing 1C 2.02465
RHAG Rh-associated glycoprotein 2.02178
DLGAP4 discs, large (Drosophila) homolog-associated protein 4 2.01983
TAC3 tachykinin 3 2.01859
MTFR1 mitochondrial fission regulator 1 2.01826
NPC1L1 NPC1-like 1 2.01811
GPX2 glutathione peroxidase 2 2.01808
TSPO2 translocator protein 2 2.01561
TMEM132A transmembrane protein 132A 2.01552
ZC4H2 zinc finger, C4H2 domain containing 2.01528
CSNK2B casein kinase 2, beta polypeptide 2.01506
RGS18 regulator of G-protein signaling 18 2.0145
HCCS holocytochrome c synthase 2.01119
CCNDBP1 cyclin D-type binding-protein 1 2.01
HPSE heparanase 2.00796
LEP leptin 2.00782
SLC12A2 solute carrier family 12 (sodium/potassium/chloride transporter), member 2 2.00576
CYB5R3 cytochrome b5 reductase 3 2.00515
TP53I3 tumor protein p53 inducible protein 3 2.00481
FLG filaggrin 2.00439
GDPD3 glycerophosphodiester phosphodiesterase domain containing 3 2.00113
PGAP3 post-GPI attachment to proteins 3 2.00093
PRSS12 protease, serine, 12 (neurotrypsin, motopsin) 2.00026

decreased expression

Symbol Name Standardized Value
UBE2C ubiquitin-conjugating enzyme E2C -9.11486
HOXA5 homeobox A5 -7.00608
TOP2A topoisomerase (DNA) II alpha 170kDa -6.87542
CDK1 cyclin-dependent kinase 1 -6.50334
HMG20B high mobility group 20B -6.43444
UQCR10 ubiquinol-cytochrome c reductase, complex III subunit X -6.2316
CDC25B cell division cycle 25B -6.05821
STMN1 stathmin 1 -5.92786
NUSAP1 nucleolar and spindle associated protein 1 -5.91522
DCK deoxycytidine kinase -5.578
SUV39H1 suppressor of variegation 3-9 homolog 1 (Drosophila) -5.16209
CDK4 cyclin-dependent kinase 4 -5.11879
PSMG1 proteasome (prosome, macropain) assembly chaperone 1 -5.00398
BLCAP bladder cancer associated protein -4.89378
CCNA2 cyclin A2 -4.83716
THAP11 THAP domain containing 11 -4.80216
PCNA proliferating cell nuclear antigen -4.58709
CENPA centromere protein A -4.554
RACGAP1 Rac GTPase activating protein 1 -4.52578
MAD2L1 MAD2 mitotic arrest deficient-like 1 (yeast) -4.48732
SDHD succinate dehydrogenase complex, subunit D, integral membrane protein -4.41981
PSIP1 PC4 and SFRS1 interacting protein 1 -4.38211
RBL1 retinoblastoma-like 1 -4.36374
TIMM9 translocase of inner mitochondrial membrane 9 homolog (yeast) -4.34884
PSRC1 proline/serine-rich coiled-coil 1 -4.34351
EZH2 enhancer of zeste 2 polycomb repressive complex 2 subunit -4.30425
MCM3 minichromosome maintenance complex component 3 -4.30234
KIF11 kinesin family member 11 -4.27744
PLK1 polo-like kinase 1 -4.27395
CCNB2 cyclin B2 -4.2642
RFC2 replication factor C (activator 1) 2, 40kDa -4.247
DSN1 DSN1, MIS12 kinetochore complex component -4.17944
OXA1L oxidase (cytochrome c) assembly 1-like -4.14157
SESN1 sestrin 1 -4.11927
KHDC4 KH domain containing 4, pre-mRNA splicing factor -4.10027
PIMREG PICALM interacting mitotic regulator -4.09942
DLGAP5 discs, large (Drosophila) homolog-associated protein 5 -4.09634
CCNB1 cyclin B1 -4.08262
BRIX1 BRX1, biogenesis of ribosomes -4.05476
FBXO5 F-box protein 5 -4.02018
POLE3 polymerase (DNA directed), epsilon 3, accessory subunit -3.97812
CDC45 cell division cycle 45 -3.97509
AURKB aurora kinase B -3.96734
RBM14-RBM4 RBM14-RBM4 readthrough -3.96302
KIF20A kinesin family member 20A -3.92827
KIF15 kinesin family member 15 -3.91685
BIRC5 baculoviral IAP repeat containing 5 -3.90209
SLC38A6 solute carrier family 38, member 6 -3.86484
SDHAF3 succinate dehydrogenase complex assembly factor 3 -3.82683
ASPM asp (abnormal spindle) homolog, microcephaly associated (Drosophila) -3.778
CDCA4 cell division cycle associated 4 -3.7772
GNPDA1 glucosamine-6-phosphate deaminase 1 -3.77548
SPC25 SPC25, NDC80 kinetochore complex component -3.77351
MBIP MAP3K12 binding inhibitory protein 1 -3.75888
DBF4 DBF4 zinc finger -3.75142
POLE2 polymerase (DNA directed), epsilon 2, accessory subunit -3.75067
CD320 CD320 molecule -3.72808
CD2 CD2 molecule -3.72468
UBR7 ubiquitin protein ligase E3 component n-recognin 7 (putative) -3.70947
YEATS4 YEATS domain containing 4 -3.68059
TTK TTK protein kinase -3.66769
COG7 component of oligomeric golgi complex 7 -3.66516
MIS18A MIS18 kinetochore protein A -3.62684
KIF14 kinesin family member 14 -3.59669
HMMR hyaluronan-mediated motility receptor (RHAMM) -3.57384
TTI1 TELO2 interacting protein 1 -3.57012
NUP62 nucleoporin 62kDa -3.56771
KIF23 kinesin family member 23 -3.56073
NEIL3 nei endonuclease VIII-like 3 (E. coli) -3.55176
PEX11B peroxisomal biogenesis factor 11 beta -3.53393
PRCP prolylcarboxypeptidase (angiotensinase C) -3.52644
NUP43 nucleoporin 43kDa -3.51098
CCNF cyclin F -3.49437
MSMO1 methylsterol monooxygenase 1 -3.46504
FABP5 fatty acid binding protein 5 (psoriasis-associated) -3.46504
BOLA1 bolA family member 1 -3.4568
CKAP2 cytoskeleton associated protein 2 -3.43987
MCM6 minichromosome maintenance complex component 6 -3.41221
HMGB2 high mobility group box 2 -3.39179
LBR lamin B receptor -3.38485
USP1 ubiquitin specific peptidase 1 -3.3631
GTPBP8 GTP-binding protein 8 (putative) -3.34909
TMEM267 transmembrane protein 267 -3.34354
LOC124900388 uncharacterized LOC124900388 -3.33218
PRPF4 pre-mRNA processing factor 4 -3.28105
CDKN3 cyclin-dependent kinase inhibitor 3 -3.27919
DENND1C DENN/MADD domain containing 1C -3.27085
RPA3 replication protein A3, 14kDa -3.26859
MPHOSPH9 M-phase phosphoprotein 9 -3.26806
CRTAP cartilage associated protein -3.24117
TOMM70 translocase of outer mitochondrial membrane 70 -3.23329
RFWD3 ring finger and WD repeat domain 3 -3.22449
RPP25 ribonuclease P/MRP 25kDa subunit -3.21481
ITGAE integrin, alpha E (antigen CD103, human mucosal lymphocyte antigen 1; alpha polypeptide) -3.21137
ASF1B anti-silencing function 1B histone chaperone -3.2078
HADH hydroxyacyl-CoA dehydrogenase -3.18945
B4GAT1 beta-1,4-glucuronyltransferase 1 -3.18425
LRIG1 leucine-rich repeats and immunoglobulin-like domains 1 -3.16889
CENPN centromere protein N -3.16849
XPO1 exportin 1 -3.15925
ANKRD10 ankyrin repeat domain 10 -3.1464
GET3 guided entry of tail-anchored proteins factor 3, ATPase -3.14544
MCM9 minichromosome maintenance complex component 9 -3.13636
RPRD2 regulation of nuclear pre-mRNA domain containing 2 -3.12209
ATF5 activating transcription factor 5 -3.12112
HSPBAP1 HSPB (heat shock 27kDa) associated protein 1 -3.11194
RPP30 ribonuclease P/MRP 30kDa subunit -3.09434
MIS12 MIS12 kinetochore complex component -3.08496
KIF18A kinesin family member 18A -3.0632
APPL1 adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 1 -3.05547
PARP1 poly (ADP-ribose) polymerase 1 -3.04994
CSTF1 cleavage stimulation factor, 3' pre-RNA, subunit 1, 50kDa -3.03851
PDSS2 prenyl (decaprenyl) diphosphate synthase, subunit 2 -3.03624
IFT52 intraflagellar transport 52 -3.03278
PALB2 partner and localizer of BRCA2 -3.02632
RAB33B RAB33B, member RAS oncogene family -3.01939
GRWD1 glutamate-rich WD repeat containing 1 -3.01928
ADI1 acireductone dioxygenase 1 -3.01168
APEX1 APEX nuclease (multifunctional DNA repair enzyme) 1 -3.00988
GINS2 GINS complex subunit 2 (Psf2 homolog) -3.00659
PARP2 poly (ADP-ribose) polymerase 2 -3.00649
POT1 protection of telomeres 1 -3.00458
AP5M1 adaptor-related protein complex 5, mu 1 subunit -2.98941
FASTKD3 FAST kinase domains 3 -2.98926
SHCBP1 SHC SH2-domain binding protein 1 -2.98566
ICE1 interactor of little elongation complex ELL subunit 1 -2.98203
USP39 ubiquitin specific peptidase 39 -2.9705
MDH1 malate dehydrogenase 1, NAD (soluble) -2.96851
MELK maternal embryonic leucine zipper kinase -2.96769
TROAP trophinin associated protein -2.96487
NEK2 NIMA-related kinase 2 -2.95003
VTA1 vesicle (multivesicular body) trafficking 1 -2.94867
DBR1 debranching RNA lariats 1 -2.94493
CEP55 centrosomal protein 55kDa -2.9432
C2CD5 C2 calcium-dependent domain containing 5 -2.9351
NOL8 nucleolar protein 8 -2.93382
DEPDC1 DEP domain containing 1 -2.91447
PBK PDZ binding kinase -2.90848
HOXA10 homeobox A10 -2.90526
DFFB DNA fragmentation factor, 40kDa, beta polypeptide (caspase-activated DNase) -2.90405
PDSS1 prenyl (decaprenyl) diphosphate synthase, subunit 1 -2.9034
EXOSC9 exosome component 9 -2.89475
FZD4 frizzled class receptor 4 -2.88099
ANXA2 annexin A2 -2.87749
SDHB succinate dehydrogenase complex, subunit B, iron sulfur (Ip) -2.87558
TRMT5 tRNA methyltransferase 5 -2.87556
CKS1B CDC28 protein kinase regulatory subunit 1B -2.87338
SASH3 SAM and SH3 domain containing 3 -2.8666
MRPL46 mitochondrial ribosomal protein L46 -2.86018
NDUFB6 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 6, 17kDa -2.85658
EPM2AIP1 EPM2A (laforin) interacting protein 1 -2.85361
CDCA3 cell division cycle associated 3 -2.85008
HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) -2.84598
ALDH3A1 aldehyde dehydrogenase 3 family, member A1 -2.84311
ANKRD49 ankyrin repeat domain 49 -2.8429
NLRP2B NLR family pyrin domain containing 2B -2.83935
THYN1 thymocyte nuclear protein 1 -2.83853
SLC5A6 solute carrier family 5 (sodium/multivitamin and iodide cotransporter), member 6 -2.83846
ZNF783 zinc finger family member 783 -2.83684
METTL17 methyltransferase like 17 -2.82639
ZNF83 zinc finger protein 83 -2.81672
PPP2R5E protein phosphatase 2, regulatory subunit B', epsilon isoform -2.80248
HJURP Holliday junction recognition protein -2.79628
LACTB2 lactamase, beta 2 -2.79594
LAGE3 L antigen family, member 3 -2.79398
SPPL2A signal peptide peptidase like 2A -2.77946
PRKAG1 protein kinase, AMP-activated, gamma 1 non-catalytic subunit -2.77825
PAIP1 poly(A) binding protein interacting protein 1 -2.77183
UBE2D1 ubiquitin-conjugating enzyme E2D 1 -2.77105
KIF4A kinesin family member 4A -2.76921
ZDHHC6 zinc finger, DHHC-type containing 6 -2.76761
TMEM38B transmembrane protein 38B -2.76748
WDR70 WD repeat domain 70 -2.76743
FAM111A family with sequence similarity 111, member A -2.76475
ZFP37 ZFP37 zinc finger protein -2.76331
DNAJC15 DnaJ (Hsp40) homolog, subfamily C, member 15 -2.75251
OIP5 Opa interacting protein 5 -2.75155
COQ3 coenzyme Q3 methyltransferase -2.74839
TSPAN6 tetraspanin 6 -2.74289
TPX2 TPX2, microtubule-associated -2.74198
HOXD11 homeobox D11 -2.73581
MCM5 minichromosome maintenance complex component 5 -2.73394
ALKBH4 alkB, alkylation repair homolog 4 (E. coli) -2.73095
ANKRD17 ankyrin repeat domain 17 -2.72701
SHQ1 SHQ1, H/ACA ribonucleoprotein assembly factor -2.72646
DVL2 dishevelled segment polarity protein 2 -2.72423
GINS1 GINS complex subunit 1 (Psf1 homolog) -2.71493
HLTF helicase-like transcription factor -2.70281
ERCC6L excision repair cross-complementation group 6-like -2.70202
CPVL carboxypeptidase, vitellogenic-like -2.70116
NCAPH non-SMC condensin I complex, subunit H -2.69763
TSC22D3 TSC22 domain family, member 3 -2.69616
POLR3K polymerase (RNA) III (DNA directed) polypeptide K, 12.3 kDa -2.69172
ZNF184 zinc finger protein 184 -2.6902
STX10 syntaxin 10 -2.68091
BAHCC1 BAH domain and coiled-coil containing 1 -2.67411
PITX1 paired-like homeodomain 1 -2.67184
MS4A4A membrane-spanning 4-domains, subfamily A, member 4A -2.66633
SKA1 spindle and kinetochore associated complex subunit 1 -2.66489
FAM200C family with sequence similarity 200 member C -2.66401
COQ2 coenzyme Q2 4-hydroxybenzoate polyprenyltransferase -2.65367
EAPP E2F-associated phosphoprotein -2.65107
MRPL3 mitochondrial ribosomal protein L3 -2.64981
G3BP1 GTPase activating protein (SH3 domain) binding protein 1 -2.64746
TFAM transcription factor A, mitochondrial -2.64251
DDIT4 DNA-damage-inducible transcript 4 -2.62982
NCAPD3 non-SMC condensin II complex, subunit D3 -2.6173
SDAD1 SDA1 domain containing 1 -2.61592
FOXM1 forkhead box M1 -2.60737
ZNF302 zinc finger protein 302 -2.60553
SLC1A3 solute carrier family 1 (glial high affinity glutamate transporter), member 3 -2.6046
ZBTB24 zinc finger and BTB domain containing 24 -2.60412
ABCF3 ATP-binding cassette, sub-family F (GCN20), member 3 -2.60412
HMGB1 high mobility group box 1 -2.59736
RFC3 replication factor C (activator 1) 3, 38kDa -2.59338
KANSL1 KAT8 regulatory NSL complex subunit 1 -2.5905
FEN1 flap structure-specific endonuclease 1 -2.58889
TEX10 testis expressed 10 -2.58598
ACP6 acid phosphatase 6, lysophosphatidic -2.58584
GCA grancalcin, EF-hand calcium binding protein -2.58548
ZNF32 zinc finger protein 32 -2.58529
KDELR1 KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 1 -2.58444
SLC35F2 solute carrier family 35, member F2 -2.5838
E2F6 E2F transcription factor 6 -2.58331
EED embryonic ectoderm development -2.57984
C1QBP complement component 1, q subcomponent binding protein -2.57716
COPZ1 coatomer protein complex, subunit zeta 1 -2.57701
ALDH9A1 aldehyde dehydrogenase 9 family, member A1 -2.57541
NIP7 NIP7, nucleolar pre-rRNA processing protein -2.56902
BTN3A2 butyrophilin, subfamily 3, member A2 -2.56215
POP5 processing of precursor 5, ribonuclease P/MRP subunit (S. cerevisiae) -2.56016
SUPT16H suppressor of Ty 16 homolog (S. cerevisiae) -2.56005
PRMT3 protein arginine methyltransferase 3 -2.55499
RBM48 RNA binding motif protein 48 -2.55128
GALNT12 polypeptide N-acetylgalactosaminyltransferase 12 -2.54957
PTTG1 pituitary tumor-transforming 1 -2.54604
NCAPG2 non-SMC condensin II complex, subunit G2 -2.54261
CISD1 CDGSH iron sulfur domain 1 -2.54243
RMI1 RecQ mediated genome instability 1 -2.53991
CDC23 cell division cycle 23 -2.52614
CRIPT cysteine-rich PDZ-binding protein -2.52027
TRAPPC4 trafficking protein particle complex 4 -2.51752
DLAT dihydrolipoamide S-acetyltransferase -2.51711
STAT1 signal transducer and activator of transcription 1, 91kDa -2.51167
MRPL19 mitochondrial ribosomal protein L19 -2.51036
MRPS34 mitochondrial ribosomal protein S34 -2.50755
TRIP13 thyroid hormone receptor interactor 13 -2.5064
PARPBP PARP1 binding protein -2.50525
COMMD9 COMM domain containing 9 -2.49631
DTL denticleless E3 ubiquitin protein ligase homolog (Drosophila) -2.49223
MS4A6A membrane-spanning 4-domains, subfamily A, member 6A -2.49111
H2AX H2A.X variant histone -2.49078
TIPIN TIMELESS interacting protein -2.48427
CYCS cytochrome c, somatic -2.48392
GNB1L guanine nucleotide binding protein (G protein), beta polypeptide 1-like -2.48074
CD58 CD58 molecule -2.47633
TRIM68 tripartite motif containing 68 -2.47507
NAT10 N-acetyltransferase 10 (GCN5-related) -2.47105
GTF2A2 general transcription factor IIA, 2, 12kDa -2.47056
OSGEPL1 O-sialoglycoprotein endopeptidase-like 1 -2.46813
HSD17B10 hydroxysteroid (17-beta) dehydrogenase 10 -2.46642
NECAB3 N-terminal EF-hand calcium binding protein 3 -2.4659
RRM1 ribonucleotide reductase M1 -2.46038
BLM Bloom syndrome, RecQ helicase-like -2.45888
MCM10 minichromosome maintenance complex component 10 -2.45779
ABHD10 abhydrolase domain containing 10 -2.45311
NCAPD2 non-SMC condensin I complex, subunit D2 -2.45172
MCM7 minichromosome maintenance complex component 7 -2.45097
UXT ubiquitously-expressed, prefoldin-like chaperone -2.44905
ZBTB35 zinc finger and BTB domain containing 35 -2.4431
MYG1 MYG1 exonuclease -2.43047
OSGEP O-sialoglycoprotein endopeptidase -2.42831
CXCR3 chemokine (C-X-C motif) receptor 3 -2.42812
HAUS6 HAUS augmin-like complex, subunit 6 -2.42372
TACC3 transforming, acidic coiled-coil containing protein 3 -2.42265
UNG uracil-DNA glycosylase -2.42224
KANSL2 KAT8 regulatory NSL complex subunit 2 -2.41592
TRAT1 T cell receptor associated transmembrane adaptor 1 -2.41585
MRPS2 mitochondrial ribosomal protein S2 -2.4119
DNTT DNA nucleotidylexotransferase -2.41061
ARFIP2 ADP-ribosylation factor interacting protein 2 -2.40989
NR1D2 nuclear receptor subfamily 1, group D, member 2 -2.4074
SPDL1 spindle apparatus coiled-coil protein 1 -2.40703
WDR6 WD repeat domain 6 -2.40469
UQCRFS1 ubiquinol-cytochrome c reductase, Rieske iron-sulfur polypeptide 1 -2.4032
UNC119B unc-119 homolog B (C. elegans) -2.40298
OXSM 3-oxoacyl-ACP synthase, mitochondrial -2.40172
RAD51C RAD51 paralog C -2.40105
ECT2 epithelial cell transforming 2 -2.39794
LIPT1 lipoyltransferase 1 -2.39569
BUB3 BUB3 mitotic checkpoint protein -2.39302
CTR9 CTR9, Paf1/RNA polymerase II complex component -2.39036
LSM5 LSM5 homolog, U6 small nuclear RNA associated (S. cerevisiae) -2.38552
LCP2 lymphocyte cytosolic protein 2 (SH2 domain containing leukocyte protein of 76kDa) -2.38498
ANP32E acidic (leucine-rich) nuclear phosphoprotein 32 family, member E -2.38392
MSL1 male-specific lethal 1 homolog (Drosophila) -2.38096
CD34 CD34 molecule -2.38023
STOML2 stomatin (EPB72)-like 2 -2.37999
NFS1 NFS1 cysteine desulfurase -2.37682
CRTC3 CREB regulated transcription coactivator 3 -2.37545
KDM3A lysine (K)-specific demethylase 3A -2.37404
FOXRED2 FAD-dependent oxidoreductase domain containing 2 -2.373
AURKA aurora kinase A -2.37178
CRY1 cryptochrome circadian clock 1 -2.3688
SDHAF1 succinate dehydrogenase complex assembly factor 1 -2.3658
TTC33 tetratricopeptide repeat domain 33 -2.36498
CCT4 chaperonin containing TCP1, subunit 4 (delta) -2.35758
ATP5MC3 ATP synthase membrane subunit c locus 3 -2.35718
DNAJC24 DnaJ (Hsp40) homolog, subfamily C, member 24 -2.3554
CSE1L CSE1 chromosome segregation 1-like (yeast) -2.3528
GCFC2 GC-rich sequence DNA-binding factor 2 -2.35156
GPATCH1 G patch domain containing 1 -2.3504
CYREN cell cycle regulator of NHEJ -2.35032
RNF130 ring finger protein 130 -2.34374
CASC3 cancer susceptibility candidate 3 -2.34159
PSMD5 proteasome (prosome, macropain) 26S subunit, non-ATPase, 5 -2.34158
ESF1 ESF1, nucleolar pre-rRNA processing protein, homolog (S. cerevisiae) -2.34039
MEPCE methylphosphate capping enzyme -2.33545
CENPU centromere protein U -2.33287
KBTBD4 kelch repeat and BTB (POZ) domain containing 4 -2.33203
PSME1 proteasome (prosome, macropain) activator subunit 1 (PA28 alpha) -2.32784
METTL1 methyltransferase like 1 -2.32637
TCTN3 tectonic family member 3 -2.32557
SPG21 spastic paraplegia 21 (autosomal recessive, Mast syndrome) -2.3212
DHTKD1 dehydrogenase E1 and transketolase domain containing 1 -2.32069
TIMM8A translocase of inner mitochondrial membrane 8 homolog A (yeast) -2.31913
PPP2R3C protein phosphatase 2, regulatory subunit B'', gamma -2.31881
CUTC cutC copper transporter -2.31413
DONSON downstream neighbor of SON -2.31271
HEATR3 HEAT repeat containing 3 -2.30872
IPO4 importin 4 -2.30843
DEK DEK proto-oncogene -2.30549
CHEK1 checkpoint kinase 1 -2.30495
MGAT4A mannosyl (alpha-1,3-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase, isozyme A -2.30447
DHX35 DEAH (Asp-Glu-Ala-His) box polypeptide 35 -2.30416
NFYB nuclear transcription factor Y, beta -2.30072
ATM ATM serine/threonine kinase -2.30041
TASOR transcription activation suppressor -2.29923
GEMIN2 gem (nuclear organelle) associated protein 2 -2.29789
EVI2B ecotropic viral integration site 2B -2.29654
KAT5 K(lysine) acetyltransferase 5 -2.29333
NPR2 natriuretic peptide receptor 2 -2.2925
TYW1 tRNA-yW synthesizing protein 1 homolog (S. cerevisiae) -2.29124
HOXA4 homeobox A4 -2.29001
METTL18 methyltransferase like 18 -2.28832
SLC35H1 solute carrier family 35 member H1 -2.28052
GOLPH3 golgi phosphoprotein 3 (coat-protein) -2.27951
LMNB1 lamin B1 -2.27895
MED21 mediator complex subunit 21 -2.27231
MGP matrix Gla protein -2.27118
FRG1 FSHD region gene 1 -2.26982
COG2 component of oligomeric golgi complex 2 -2.26446
TLR4 toll-like receptor 4 -2.26284
AIM2 absent in melanoma 2 -2.26026
SKAP2 src kinase associated phosphoprotein 2 -2.25951
FAM216A family with sequence similarity 216, member A -2.2587
HLA-DRB3 major histocompatibility complex, class II, DR beta 3 -2.25758
SIVA1 SIVA1, apoptosis-inducing factor -2.25737
CAND1 cullin-associated and neddylation-dissociated 1 -2.25622
STK11 serine/threonine kinase 11 -2.25167
SMC5 structural maintenance of chromosomes 5 -2.24794
MKKS McKusick-Kaufman syndrome -2.24529
TOPBP1 topoisomerase (DNA) II binding protein 1 -2.24294
TTC28 tetratricopeptide repeat domain 28 -2.24201
ISOC2 isochorismatase domain containing 2 -2.24157
SEMA4D sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D -2.24133
NPM3 nucleophosmin/nucleoplasmin 3 -2.23751
GYS1 glycogen synthase 1 (muscle) -2.23648
MPV17 MpV17 mitochondrial inner membrane protein -2.23465
MRPL34 mitochondrial ribosomal protein L34 -2.23017
TSEN2 TSEN2 tRNA splicing endonuclease subunit -2.22893
POLR2L polymerase (RNA) II (DNA directed) polypeptide L, 7.6kDa -2.2286
ZNF189 zinc finger protein 189 -2.22684
BORA bora, aurora kinase A activator -2.2247
MRFAP1L1 Morf4 family associated protein 1-like 1 -2.22403
ZNF106 zinc finger protein 106 -2.22365
DECR1 2,4-dienoyl CoA reductase 1, mitochondrial -2.2227
GINS3 GINS complex subunit 3 (Psf3 homolog) -2.22189
RAD51AP1 RAD51 associated protein 1 -2.22137
RXRA retinoid X receptor, alpha -2.22108
ZNF443 zinc finger protein 443 -2.21938
SLC37A4 solute carrier family 37 (glucose-6-phosphate transporter), member 4 -2.21924
MANEA mannosidase, endo-alpha -2.21908
ZBED5 zinc finger, BED-type containing 5 -2.21898
ZNF146 zinc finger protein 146 -2.21891
DROSHA drosha, ribonuclease type III -2.2186
DNA2 DNA replication helicase/nuclease 2 -2.21697
TRIM28 tripartite motif containing 28 -2.21404
PUS3 pseudouridylate synthase 3 -2.21213
NUP37 nucleoporin 37kDa -2.20724
CEBPA CCAAT/enhancer binding protein (C/EBP), alpha -2.20416
PDCD6 programmed cell death 6 -2.20218
TRIP6 thyroid hormone receptor interactor 6 -2.20087
DPYD dihydropyrimidine dehydrogenase -2.19835
FBXW2 F-box and WD repeat domain containing 2 -2.1959
ABITRAM actin binding transcription modulator -2.19494
DCPS decapping enzyme, scavenger -2.19447
KCNJ16 potassium channel, inwardly rectifying subfamily J, member 16 -2.19313
DDB2 damage-specific DNA binding protein 2, 48kDa -2.19284
NNT nicotinamide nucleotide transhydrogenase -2.19193
RTCB RNA 2',3'-cyclic phosphate and 5'-OH ligase -2.19129
SUB1 SUB1 homolog (S. cerevisiae) -2.18415
SPINK2 serine peptidase inhibitor, Kazal type 2 (acrosin-trypsin inhibitor) -2.1839
PA2G4 proliferation-associated 2G4, 38kDa -2.18342
MRPL12 mitochondrial ribosomal protein L12 -2.1833
GRAMD4 GRAM domain containing 4 -2.18148
GNG10 guanine nucleotide binding protein (G protein), gamma 10 -2.18028
PRPF8 pre-mRNA processing factor 8 -2.17927
UBA2 ubiquitin-like modifier activating enzyme 2 -2.17882
ASCC2 activating signal cointegrator 1 complex subunit 2 -2.17616
RNASE7 ribonuclease, RNase A family, 7 -2.17565
MRPS16 mitochondrial ribosomal protein S16 -2.17528
PAGR1 PAXIP1 associated glutamate-rich protein 1 -2.17442
POLR1G RNA polymerase I subunit G -2.17409
GRSF1 G-rich RNA sequence binding factor 1 -2.17144
FUCA1 fucosidase, alpha-L- 1, tissue -2.17044
MRPS27 mitochondrial ribosomal protein S27 -2.16714
ACOD1 aconitate decarboxylase 1 -2.16561
PUS1 pseudouridylate synthase 1 -2.16036
RPIA ribose 5-phosphate isomerase A -2.15632
POLA2 polymerase (DNA directed), alpha 2, accessory subunit -2.15628
HNRNPR heterogeneous nuclear ribonucleoprotein R -2.15542
SAE1 SUMO1 activating enzyme subunit 1 -2.1545
TTC31 tetratricopeptide repeat domain 31 -2.15403
NKAPD1 NKAP domain containing 1 -2.15395
ALG9 ALG9, alpha-1,2-mannosyltransferase -2.15362
TXNDC9 thioredoxin domain containing 9 -2.14962
GTSE1 G-2 and S-phase expressed 1 -2.14689
HDAC2 histone deacetylase 2 -2.145
GLOD4 glyoxalase domain containing 4 -2.14477
GCSH glycine cleavage system protein H (aminomethyl carrier) -2.14203
VRK1 vaccinia related kinase 1 -2.14065
GZMM granzyme M (lymphocyte met-ase 1) -2.13908
KIF18B kinesin family member 18B -2.13898
TARP TCR gamma alternate reading frame protein -2.13772
SNUPN snurportin 1 -2.13722
TP53RK TP53 regulating kinase -2.13648
PIK3R1 phosphoinositide-3-kinase, regulatory subunit 1 (alpha) -2.13507
ETFB electron-transfer-flavoprotein, beta polypeptide -2.13449
NUP133 nucleoporin 133kDa -2.13072
RBM23 RNA binding motif protein 23 -2.12974
AHR aryl hydrocarbon receptor -2.12972
MCRS1 microspherule protein 1 -2.12899
RFC4 replication factor C (activator 1) 4, 37kDa -2.12708
SF3B3 splicing factor 3b, subunit 3, 130kDa -2.12673
RNF220 ring finger protein 220 -2.12505
RINT1 RAD50 interactor 1 -2.12151
MRPL17 mitochondrial ribosomal protein L17 -2.12078
GALNT11 polypeptide N-acetylgalactosaminyltransferase 11 -2.11626
HSD17B7 hydroxysteroid (17-beta) dehydrogenase 7 -2.11511
MAZ MYC-associated zinc finger protein (purine-binding transcription factor) -2.11188
GPN3 GPN-loop GTPase 3 -2.10588
MDC1 mediator of DNA-damage checkpoint 1 -2.10517
RNF144A ring finger protein 144A -2.09729
CMC2 C-x(9)-C motif containing 2 -2.09498
NUP42 nucleoporin 42 -2.09438
TMPO thymopoietin -2.09059
ECHS1 enoyl CoA hydratase, short chain, 1, mitochondrial -2.08915
ANAPC1 anaphase promoting complex subunit 1 -2.0876
PFAS phosphoribosylformylglycinamidine synthase -2.08665
MSL2 male-specific lethal 2 homolog (Drosophila) -2.08643
TBC1D2B TBC1 domain family, member 2B -2.08618
POLE polymerase (DNA directed), epsilon, catalytic subunit -2.08514
CBLL1 Cbl proto-oncogene-like 1, E3 ubiquitin protein ligase -2.08253
COQ6 coenzyme Q6 monooxygenase -2.08149
ATAD2 ATPase family, AAA domain containing 2 -2.08008
TNNC1 troponin C type 1 (slow) -2.07987
MIS18BP1 MIS18 binding protein 1 -2.07877
SRP54 signal recognition particle 54kDa -2.07862
COASY CoA synthase -2.07848
CENPS-CORT CENPS-CORT readthrough -2.07673
EML4 echinoderm microtubule associated protein like 4 -2.07641
FGL2 fibrinogen-like 2 -2.07445
CPNE3 copine III -2.07303
LETMD1 LETM1 domain containing 1 -2.07282
HMGN2 high mobility group nucleosomal binding domain 2 -2.07217
GTF3C4 general transcription factor IIIC, polypeptide 4, 90kDa -2.07055
SOBP sine oculis binding protein homolog (Drosophila) -2.06835
MKI67 marker of proliferation Ki-67 -2.06393
WDR18 WD repeat domain 18 -2.06176
MCMBP minichromosome maintenance complex binding protein -2.05938
ACYP1 acylphosphatase 1, erythrocyte (common) type -2.05836
SCML2 sex comb on midleg-like 2 (Drosophila) -2.05762
SNRPE small nuclear ribonucleoprotein polypeptide E -2.05325
ABI3BP ABI family, member 3 (NESH) binding protein -2.05245
KIF20B kinesin family member 20B -2.05043
GPR65 G protein-coupled receptor 65 -2.04944
ZNF26 zinc finger protein 26 -2.0494
ADNP activity-dependent neuroprotector homeobox -2.04821
PCLAF PCNA clamp associated factor -2.04816
RYK receptor-like tyrosine kinase -2.0469
PRPF31 pre-mRNA processing factor 31 -2.04217
CDC6 cell division cycle 6 -2.03778
RUVBL1 RuvB-like AAA ATPase 1 -2.03592
NPAT nuclear protein, ataxia-telangiectasia locus -2.03185
LYSET lysosomal enzyme trafficking factor -2.03083
SACS sacsin molecular chaperone -2.02869
TEFM transcription elongation factor, mitochondrial -2.02869
DPAGT1 dolichyl-phosphate (UDP-N-acetylglucosamine) N-acetylglucosaminephosphotransferase 1 (GlcNAc-1-P transferase) -2.02819
NABP2 nucleic acid binding protein 2 -2.02793
TOPORS topoisomerase I binding, arginine/serine-rich, E3 ubiquitin protein ligase -2.02453
RBMX RNA binding motif protein, X-linked -2.02394
XPA xeroderma pigmentosum, complementation group A -2.02349
TMEM185B transmembrane protein 185B -2.02248
ZNF274 zinc finger protein 274 -2.01929
CENPC centromere protein C -2.01904
DCLRE1A DNA cross-link repair 1A -2.01859
ATP5MC1 ATP synthase membrane subunit c locus 1 -2.01774
PRC1 protein regulator of cytokinesis 1 -2.01674
RANBP6 RAN binding protein 6 -2.0151
RWDD1 RWD domain containing 1 -2.01423
SLC61A1 solute carrier family 61 member 1 -2.01299
APOBEC2 apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 2 -2.01275
IL2RG interleukin 2 receptor, gamma -2.01191
CLN6 ceroid-lipofuscinosis, neuronal 6, late infantile, variant -2.01174
FASTK Fas-activated serine/threonine kinase -2.01088
MAP3K6 mitogen-activated protein kinase kinase kinase 6 -2.01079
GOLM1 golgi membrane protein 1 -2.00998
PRELID3B PRELI domain containing 3B -2.00645
SPATS2 spermatogenesis associated, serine-rich 2 -2.00635
NOP56 NOP56 ribonucleoprotein -2.00573
PREB prolactin regulatory element binding -2.00557
CHST10 carbohydrate sulfotransferase 10 -2.00429
CHEK2 checkpoint kinase 2 -2.00354
SUOX sulfite oxidase -2.00211
ING1 inhibitor of growth family, member 1 -2.00174
ATRIP ATR interacting protein -2.00066
NUP205 nucleoporin 205kDa -2.0