CRCGN017_MCF10A.TP53.M_24H:E09 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description rotenone 11.33 um perturbation at 24 h in MCF10A.TP53.M (Carcinogenome)
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Genes

489 genes differentially expressed following the CRCGN017_MCF10A.TP53.M_24H:E09 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) 7.55664
SQOR sulfide quinone oxidoreductase 5.69845
TNIP1 TNFAIP3 interacting protein 1 5.61153
TP53BP2 tumor protein p53 binding protein 2 4.85424
STXBP1 syntaxin binding protein 1 4.66492
COMP cartilage oligomeric matrix protein 4.63239
IGFBP3 insulin-like growth factor binding protein 3 4.32339
WIF1 WNT inhibitory factor 1 4.32203
RELB v-rel avian reticuloendotheliosis viral oncogene homolog B 4.30377
TICAM1 toll-like receptor adaptor molecule 1 4.28448
MSRA methionine sulfoxide reductase A 4.1158
SLC2A6 solute carrier family 2 (facilitated glucose transporter), member 6 4.08545
CXCL2 chemokine (C-X-C motif) ligand 2 3.93219
SNAP25 synaptosomal-associated protein, 25kDa 3.93215
IL1B interleukin 1, beta 3.84823
STAP2 signal transducing adaptor family member 2 3.76981
DUSP14 dual specificity phosphatase 14 3.76823
CHIC2 cysteine-rich hydrophobic domain 2 3.71678
GPER1 G protein-coupled estrogen receptor 1 3.56068
TIMP2 TIMP metallopeptidase inhibitor 2 3.52619
ALAS1 5'-aminolevulinate synthase 1 3.49215
SYNGAP1 synaptic Ras GTPase activating protein 1 3.44724
UGDH UDP-glucose 6-dehydrogenase 3.42866
SLC75A1 solute carrier family 75 member 1 3.42079
NCK2 NCK adaptor protein 2 3.15275
CAB39 calcium binding protein 39 3.13351
PPARG peroxisome proliferator-activated receptor gamma 3.00234
CDCP1 CUB domain containing protein 1 2.99785
SLC37A1 solute carrier family 37 (glucose-6-phosphate transporter), member 1 2.99438
YIPF1 Yip1 domain family, member 1 2.98333
TPM1 tropomyosin 1 (alpha) 2.9566
APOBEC3F apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3F 2.91741
CXCL3 chemokine (C-X-C motif) ligand 3 2.90534
ZNF586 zinc finger protein 586 2.88453
MYH9 myosin, heavy chain 9, non-muscle 2.86782
PLOD3 procollagen-lysine, 2-oxoglutarate 5-dioxygenase 3 2.85027
KLC3 kinesin light chain 3 2.84881
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 2.84853
CHAC1 ChaC glutathione-specific gamma-glutamylcyclotransferase 1 2.82248
FGFR4 fibroblast growth factor receptor 4 2.80463
OSBPL2 oxysterol binding protein-like 2 2.80095
MYL9 myosin, light chain 9, regulatory 2.79212
ERVMER34-1 endogenous retrovirus group MER34, member 1 2.76988
SMIM40 small integral membrane protein 40 2.72861
KCNK1 potassium channel, two pore domain subfamily K, member 1 2.71756
H2BC12 H2B clustered histone 12 2.70813
IGHMBP2 immunoglobulin mu binding protein 2 2.70731
WDR44 WD repeat domain 44 2.70351
PPP2R5B protein phosphatase 2, regulatory subunit B', beta 2.66997
GNL1 guanine nucleotide binding protein-like 1 2.66768
PIEZO1 piezo-type mechanosensitive ion channel component 1 2.6506
ZC3H12A zinc finger CCCH-type containing 12A 2.6477
AVEN apoptosis, caspase activation inhibitor 2.64701
CAB39L calcium binding protein 39-like 2.64304
RAB11FIP2 RAB11 family interacting protein 2 (class I) 2.63004
ATOSB atos homolog B 2.61247
ASAP2 ArfGAP with SH3 domain, ankyrin repeat and PH domain 2 2.61115
CCL20 chemokine (C-C motif) ligand 20 2.61104
SLC25A14 solute carrier family 25 (mitochondrial carrier, brain), member 14 2.59862
TNFAIP1 tumor necrosis factor, alpha-induced protein 1 (endothelial) 2.59746
MMP1 matrix metallopeptidase 1 2.59585
CEMIP2 cell migration inducing hyaluronidase 2 2.59383
GARS1 glycyl-tRNA synthetase 1 2.56007
IL15RA interleukin 15 receptor, alpha 2.55833
VRTN vertebrae development associated 2.55075
STK10 serine/threonine kinase 10 2.52231
CSF3 colony stimulating factor 3 (granulocyte) 2.51562
CYP2W1 cytochrome P450, family 2, subfamily W, polypeptide 1 2.51269
FAT1 FAT atypical cadherin 1 2.50886
ADRM1 adhesion regulating molecule 1 2.49662
ISG15 ISG15 ubiquitin-like modifier 2.49342
SNCA synuclein, alpha (non A4 component of amyloid precursor) 2.47231
PDZD8 PDZ domain containing 8 2.46134
KIF25 kinesin family member 25 2.46107
RASL11B RAS-like, family 11, member B 2.44767
SLC6A11 solute carrier family 6 (neurotransmitter transporter), member 11 2.43709
TAGLN3 transgelin 3 2.43456
PLXNA1 plexin A1 2.43286
LRRC59 leucine rich repeat containing 59 2.42974
PCGF3 polycomb group ring finger 3 2.42768
ISG20 interferon stimulated exonuclease gene 20kDa 2.42325
CTSZ cathepsin Z 2.42163
PARP12 poly (ADP-ribose) polymerase family, member 12 2.41733
COL17A1 collagen, type XVII, alpha 1 2.41166
SEMA6B sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6B 2.40897
IL1A interleukin 1, alpha 2.40762
CES3 carboxylesterase 3 2.39795
NUP93 nucleoporin 93kDa 2.39189
OR10H1 olfactory receptor, family 10, subfamily H, member 1 2.3918
CIRSR corepressor of RBPJ and splicing regulator 2.38675
KCMF1 potassium channel modulatory factor 1 2.37108
GRB7 growth factor receptor-bound protein 7 2.36216
PLAU plasminogen activator, urokinase 2.36177
RIPOR1 RHO family interacting cell polarization regulator 1 2.35301
BIRC7 baculoviral IAP repeat containing 7 2.3528
RIPK2 receptor-interacting serine-threonine kinase 2 2.35244
ARHGAP8 Rho GTPase activating protein 8 2.35226
SAMD14 sterile alpha motif domain containing 14 2.34846
WNT5B wingless-type MMTV integration site family, member 5B 2.34186
PCDHB13 protocadherin beta 13 2.33678
KRT3 keratin 3, type II 2.33102
ODAD2 outer dynein arm docking complex subunit 2 2.33077
CTTN cortactin 2.32948
MAPK3 mitogen-activated protein kinase 3 2.32846
BMPR2 bone morphogenetic protein receptor, type II (serine/threonine kinase) 2.32258
PHF13 PHD finger protein 13 2.32005
EPN3 epsin 3 2.31756
DLGAP4 discs, large (Drosophila) homolog-associated protein 4 2.31708
WWC2 WW and C2 domain containing 2 2.31678
WNT7A wingless-type MMTV integration site family, member 7A 2.31609
BCORL1 BCL6 corepressor-like 1 2.30675
IER3 immediate early response 3 2.29307
TRAF3 TNF receptor-associated factor 3 2.28949
SNCB synuclein, beta 2.28537
TCIRG1 T-cell, immune regulator 1, ATPase, H+ transporting, lysosomal V0 subunit A3 2.27548
SLC12A4 solute carrier family 12 (potassium/chloride transporter), member 4 2.27446
BDKRB2 bradykinin receptor B2 2.26967
CNIH4 cornichon family AMPA receptor auxiliary protein 4 2.26685
GNA15 guanine nucleotide binding protein (G protein), alpha 15 (Gq class) 2.26187
MARCHF2 membrane associated ring-CH-type finger 2 2.25578
OTUB2 OTU deubiquitinase, ubiquitin aldehyde binding 2 2.25298
CCDC85C coiled-coil domain containing 85C 2.25168
CBARP CACN subunit beta associated regulatory protein 2.24976
SCT secretin 2.24908
MAP1LC3B microtubule-associated protein 1 light chain 3 beta 2.24555
SBNO2 strawberry notch homolog 2 (Drosophila) 2.23982
SEMA3C sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C 2.2394
PLD2 phospholipase D2 2.23851
GPC1 glypican 1 2.22549
SLC26A1 solute carrier family 26 (anion exchanger), member 1 2.22425
ADRA2C adrenoceptor alpha 2C 2.22332
MMP9 matrix metallopeptidase 9 2.21996
TGFA transforming growth factor, alpha 2.2167
CDPF1 cysteine-rich, DPF motif domain containing 1 2.21568
RUNDC3A RUN domain containing 3A 2.21383
ZDHHC14 zinc finger, DHHC-type containing 14 2.21144
NSG2 neuronal vesicle trafficking associated 2 2.21013
CDH22 cadherin 22, type 2 2.21011
UBTD1 ubiquitin domain containing 1 2.20795
XKR8 XK, Kell blood group complex subunit-related family, member 8 2.20657
TMEM184B transmembrane protein 184B 2.20253
SPINT1 serine peptidase inhibitor, Kunitz type 1 2.20249
THBS1 thrombospondin 1 2.20228
IFNGR2 interferon gamma receptor 2 (interferon gamma transducer 1) 2.19926
ZMPSTE24 zinc metallopeptidase STE24 2.19866
NT5E 5'-nucleotidase, ecto (CD73) 2.19737
ANKRD40 ankyrin repeat domain 40 2.18511
NECAP1 NECAP endocytosis associated 1 2.18501
NOTCH1 notch 1 2.18207
MAP3K11 mitogen-activated protein kinase kinase kinase 11 2.18169
TXNRD1 thioredoxin reductase 1 2.18158
MADCAM1 mucosal vascular addressin cell adhesion molecule 1 2.18026
CD177 CD177 molecule 2.17663
PTPRS protein tyrosine phosphatase, receptor type, S 2.17507
STMN2 stathmin 2 2.17497
CAV1 caveolin 1, caveolae protein, 22kDa 2.17492
TERF2IP telomeric repeat binding factor 2, interacting protein 2.17482
NTAN1 N-terminal asparagine amidase 2.1734
CRIM1 cysteine rich transmembrane BMP regulator 1 (chordin-like) 2.17124
OSBPL3 oxysterol binding protein-like 3 2.17004
PLA2G15 phospholipase A2, group XV 2.16983
MINDY3 MINDY lysine 48 deubiquitinase 3 2.16744
CCND3 cyclin D3 2.16716
CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa 2.16677
SLC7A10 solute carrier family 7 (neutral amino acid transporter light chain, asc system), member 10 2.16543
XPNPEP1 X-prolyl aminopeptidase (aminopeptidase P) 1, soluble 2.16527
LIMS2 LIM and senescent cell antigen-like domains 2 2.16458
SH2B3 SH2B adaptor protein 3 2.16368
RAB6B RAB6B, member RAS oncogene family 2.15992
IL20RA interleukin 20 receptor, alpha 2.15849
MACO1 macoilin 1 2.15002
ACTR1A ARP1 actin-related protein 1 homolog A, centractin alpha (yeast) 2.14908
TRIM36 tripartite motif containing 36 2.14871
BAMBI BMP and activin membrane-bound inhibitor 2.14739
JMJD6 jumonji domain containing 6 2.13929
RTCA RNA 3'-terminal phosphate cyclase 2.13257
MTFR1 mitochondrial fission regulator 1 2.1324
DEF8 differentially expressed in FDCP 8 homolog (mouse) 2.13086
MORN1 MORN repeat containing 1 2.13057
TM6SF1 transmembrane 6 superfamily member 1 2.12096
GRAMD2B GRAM domain containing 2B 2.119
CACNA1B calcium channel, voltage-dependent, N type, alpha 1B subunit 2.11759
EXD3 exonuclease 3'-5' domain containing 3 2.11478
RALA v-ral simian leukemia viral oncogene homolog A (ras related) 2.10809
DHX32 DEAH (Asp-Glu-Ala-His) box polypeptide 32 2.1078
RNLS renalase, FAD-dependent amine oxidase 2.10699
TP53TG5 TP53 target 5 2.10652
PSEN2 presenilin 2 2.10641
SIPA1L3 signal-induced proliferation-associated 1 like 3 2.10588
NADSYN1 NAD synthetase 1 2.10176
GPRC5D G protein-coupled receptor, class C, group 5, member D 2.09843
LAMC2 laminin, gamma 2 2.09485
ACOT9 acyl-CoA thioesterase 9 2.08861
IP6K2 inositol hexakisphosphate kinase 2 2.08849
MMP24OS MMP24 opposite strand 2.08773
GLRX glutaredoxin (thioltransferase) 2.08606
BMP2 bone morphogenetic protein 2 2.08602
CTIF CBP80/20-dependent translation initiation factor 2.08436
TMBIM1 transmembrane BAX inhibitor motif containing 1 2.08347
SLC12A5 solute carrier family 12 (potassium/chloride transporter), member 5 2.08242
ADCYAP1R1 adenylate cyclase activating polypeptide 1 (pituitary) receptor type I 2.08034
IFT54 intraflagellar transport 54 2.08018
DBN1 drebrin 1 2.07833
DDX41 DEAD (Asp-Glu-Ala-Asp) box polypeptide 41 2.07816
ZSCAN2 zinc finger and SCAN domain containing 2 2.07808
POMT2 protein-O-mannosyltransferase 2 2.07675
ITFG1 integrin alpha FG-GAP repeat containing 1 2.07198
CD74 CD74 molecule, major histocompatibility complex, class II invariant chain 2.06917
GAS6 growth arrest-specific 6 2.06905
PLAUR plasminogen activator, urokinase receptor 2.06772
RAMP1 receptor (G protein-coupled) activity modifying protein 1 2.06377
H2BC21 H2B clustered histone 21 2.0479
FHIP2B FHF complex subunit HOOK interacting protein 2B 2.04748
GCC1 GRIP and coiled-coil domain containing 1 2.03973
FRYL FRY-like 2.03886
EMC7 ER membrane protein complex subunit 7 2.03674
LRP10 low density lipoprotein receptor-related protein 10 2.03658
LETM1 leucine zipper-EF-hand containing transmembrane protein 1 2.03437
TES testin LIM domain protein 2.02999
PODNL1 podocan-like 1 2.02872
RAB9A RAB9A, member RAS oncogene family 2.02672
SOX4 SRY (sex determining region Y)-box 4 2.01851
LRRK1 leucine-rich repeat kinase 1 2.01465
PIGU phosphatidylinositol glycan anchor biosynthesis, class U 2.01359
CXCL1 chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha) 2.01352
RPS6KA2 ribosomal protein S6 kinase, 90kDa, polypeptide 2 2.01205
PHLDA2 pleckstrin homology-like domain, family A, member 2 2.01132
DNAH7 dynein, axonemal, heavy chain 7 2.00824
IL4R interleukin 4 receptor 2.00307
TOM1L2 target of myb1-like 2 (chicken) 2.00058

decreased expression

Symbol Name Standardized Value
UBE2C ubiquitin-conjugating enzyme E2C -9.37077
TOP2A topoisomerase (DNA) II alpha 170kDa -7.59546
CDK1 cyclin-dependent kinase 1 -6.75726
NUSAP1 nucleolar and spindle associated protein 1 -6.31023
CDC25B cell division cycle 25B -5.58515
HOXA5 homeobox A5 -4.68817
KIF11 kinesin family member 11 -4.14265
ANXA2 annexin A2 -4.09745
KHDC4 KH domain containing 4, pre-mRNA splicing factor -4.09583
UQCR10 ubiquinol-cytochrome c reductase, complex III subunit X -4.08903
HADH hydroxyacyl-CoA dehydrogenase -3.95384
RFC2 replication factor C (activator 1) 2, 40kDa -3.90729
CDK4 cyclin-dependent kinase 4 -3.87153
CLPX caseinolytic mitochondrial matrix peptidase chaperone subunit -3.82174
PSRC1 proline/serine-rich coiled-coil 1 -3.80627
ASF1B anti-silencing function 1B histone chaperone -3.79309
NEIL3 nei endonuclease VIII-like 3 (E. coli) -3.74601
PSMB8 proteasome (prosome, macropain) subunit, beta type, 8 -3.70881
SESN1 sestrin 1 -3.67146
TIMM9 translocase of inner mitochondrial membrane 9 homolog (yeast) -3.66593
NLRP4 NLR family, pyrin domain containing 4 -3.65273
ADI1 acireductone dioxygenase 1 -3.56611
USP1 ubiquitin specific peptidase 1 -3.55962
DNAJC15 DnaJ (Hsp40) homolog, subfamily C, member 15 -3.53383
PUF60 poly-U binding splicing factor 60KDa -3.50251
MAD2L1 MAD2 mitotic arrest deficient-like 1 (yeast) -3.47425
CDCA4 cell division cycle associated 4 -3.46955
B4GAT1 beta-1,4-glucuronyltransferase 1 -3.45232
ASPM asp (abnormal spindle) homolog, microcephaly associated (Drosophila) -3.41981
CD58 CD58 molecule -3.41023
DDIT4 DNA-damage-inducible transcript 4 -3.3686
CCNA2 cyclin A2 -3.36329
GRWD1 glutamate-rich WD repeat containing 1 -3.33988
EZH2 enhancer of zeste 2 polycomb repressive complex 2 subunit -3.32856
GNPDA1 glucosamine-6-phosphate deaminase 1 -3.32221
CENPA centromere protein A -3.32132
FOXRED2 FAD-dependent oxidoreductase domain containing 2 -3.31024
EAPP E2F-associated phosphoprotein -3.29423
MELK maternal embryonic leucine zipper kinase -3.27663
NAT10 N-acetyltransferase 10 (GCN5-related) -3.21637
AURKB aurora kinase B -3.18355
PSMG1 proteasome (prosome, macropain) assembly chaperone 1 -3.15536
KIF14 kinesin family member 14 -3.13133
PLK1 polo-like kinase 1 -3.12638
HMGB2 high mobility group box 2 -3.11868
PITX1 paired-like homeodomain 1 -3.10343
SNX5 sorting nexin 5 -3.0825
PIMREG PICALM interacting mitotic regulator -3.02682
TSC22D3 TSC22 domain family, member 3 -3.0021
CASC3 cancer susceptibility candidate 3 -2.98555
ANKRD10 ankyrin repeat domain 10 -2.95825
FBXO5 F-box protein 5 -2.94979
STMN1 stathmin 1 -2.93464
CIRBP cold inducible RNA binding protein -2.92258
BLCAP bladder cancer associated protein -2.90717
RACGAP1 Rac GTPase activating protein 1 -2.88808
ETFB electron-transfer-flavoprotein, beta polypeptide -2.87981
CDC45 cell division cycle 45 -2.86053
CCNB2 cyclin B2 -2.84336
SLC37A4 solute carrier family 37 (glucose-6-phosphate transporter), member 4 -2.80681
DLGAP5 discs, large (Drosophila) homolog-associated protein 5 -2.78041
RPA3 replication protein A3, 14kDa -2.77614
NCAPG2 non-SMC condensin II complex, subunit G2 -2.75782
DNAJA3 DnaJ (Hsp40) homolog, subfamily A, member 3 -2.75374
TRMT5 tRNA methyltransferase 5 -2.74121
GINS1 GINS complex subunit 1 (Psf1 homolog) -2.7116
CCNF cyclin F -2.69511
ETV1 ets variant 1 -2.69165
SPDL1 spindle apparatus coiled-coil protein 1 -2.68885
NUP133 nucleoporin 133kDa -2.67118
TSPAN6 tetraspanin 6 -2.66487
TOMM70 translocase of outer mitochondrial membrane 70 -2.65893
PRKCD protein kinase C, delta -2.64857
BTN3A2 butyrophilin, subfamily 3, member A2 -2.63999
SOBP sine oculis binding protein homolog (Drosophila) -2.63459
LACTB2 lactamase, beta 2 -2.61989
TMED10 transmembrane emp24-like trafficking protein 10 (yeast) -2.61649
HNRNPF heterogeneous nuclear ribonucleoprotein F -2.59505
SPPL2A signal peptide peptidase like 2A -2.57875
PRKAG1 protein kinase, AMP-activated, gamma 1 non-catalytic subunit -2.56964
OXSM 3-oxoacyl-ACP synthase, mitochondrial -2.56333
TMEM186 transmembrane protein 186 -2.55529
CEP55 centrosomal protein 55kDa -2.55229
CDC6 cell division cycle 6 -2.55003
MRPL12 mitochondrial ribosomal protein L12 -2.53654
APEX1 APEX nuclease (multifunctional DNA repair enzyme) 1 -2.53158
PCNA proliferating cell nuclear antigen -2.5309
TTC31 tetratricopeptide repeat domain 31 -2.52085
DCK deoxycytidine kinase -2.50745
RBKS ribokinase -2.50435
HMMR hyaluronan-mediated motility receptor (RHAMM) -2.50293
DEK DEK proto-oncogene -2.50107
WDR5B WD repeat domain 5B -2.48469
CDC37L1 cell division cycle 37-like 1 -2.47872
GATD3 glutamine amidotransferase class 1 domain containing 3 -2.47745
BOLA1 bolA family member 1 -2.47325
PRUNE1 prune exopolyphosphatase 1 -2.46356
FEN1 flap structure-specific endonuclease 1 -2.46123
ATP1B1 ATPase, Na+/K+ transporting, beta 1 polypeptide -2.45758
CPVL carboxypeptidase, vitellogenic-like -2.44129
DBF4 DBF4 zinc finger -2.43757
ADGRE5 adhesion G protein-coupled receptor E5 -2.43256
TTK TTK protein kinase -2.42645
PPP2R3C protein phosphatase 2, regulatory subunit B'', gamma -2.4244
ITGAE integrin, alpha E (antigen CD103, human mucosal lymphocyte antigen 1; alpha polypeptide) -2.41814
DSN1 DSN1, MIS12 kinetochore complex component -2.41777
ERAP2 endoplasmic reticulum aminopeptidase 2 -2.40917
MCM9 minichromosome maintenance complex component 9 -2.40038
MEPCE methylphosphate capping enzyme -2.39888
SUCLG2 succinate-CoA ligase, GDP-forming, beta subunit -2.39563
ACADM acyl-CoA dehydrogenase, C-4 to C-12 straight chain -2.39381
OXA1L oxidase (cytochrome c) assembly 1-like -2.38852
SDHC succinate dehydrogenase complex, subunit C, integral membrane protein, 15kDa -2.38601
ZNF571 zinc finger protein 571 -2.38556
DTL denticleless E3 ubiquitin protein ligase homolog (Drosophila) -2.38429
KIF15 kinesin family member 15 -2.37852
EED embryonic ectoderm development -2.37799
HMGN1 high mobility group nucleosome binding domain 1 -2.37424
HLA-DRB3 major histocompatibility complex, class II, DR beta 3 -2.37212
NCAPD2 non-SMC condensin I complex, subunit D2 -2.3685
ANAPC1 anaphase promoting complex subunit 1 -2.36044
PTCD3 pentatricopeptide repeat domain 3 -2.35996
SPTSSA serine palmitoyltransferase, small subunit A -2.35698
NEK2 NIMA-related kinase 2 -2.3569
GEMIN2 gem (nuclear organelle) associated protein 2 -2.3534
BIRC5 baculoviral IAP repeat containing 5 -2.34929
GTPBP8 GTP-binding protein 8 (putative) -2.34453
AP5M1 adaptor-related protein complex 5, mu 1 subunit -2.34233
EHHADH enoyl-CoA, hydratase/3-hydroxyacyl CoA dehydrogenase -2.336
METTL17 methyltransferase like 17 -2.33127
YEATS4 YEATS domain containing 4 -2.33072
SDR39U1 short chain dehydrogenase/reductase family 39U, member 1 -2.328
FIS1 fission 1 (mitochondrial outer membrane) homolog (S. cerevisiae) -2.32617
PPA2 pyrophosphatase (inorganic) 2 -2.32451
TRAT1 T cell receptor associated transmembrane adaptor 1 -2.31921
PSME1 proteasome (prosome, macropain) activator subunit 1 (PA28 alpha) -2.31915
RBL1 retinoblastoma-like 1 -2.31854
CDKN3 cyclin-dependent kinase inhibitor 3 -2.30863
SPG21 spastic paraplegia 21 (autosomal recessive, Mast syndrome) -2.30064
COMMD10 COMM domain containing 10 -2.29944
KANSL2 KAT8 regulatory NSL complex subunit 2 -2.29834
PACSIN3 protein kinase C and casein kinase substrate in neurons 3 -2.29232
KIF23 kinesin family member 23 -2.29063
TMEM267 transmembrane protein 267 -2.28884
DDX50 DEAD (Asp-Glu-Ala-Asp) box polypeptide 50 -2.28523
MDH1 malate dehydrogenase 1, NAD (soluble) -2.2803
SHMT1 serine hydroxymethyltransferase 1 (soluble) -2.27509
KANSL1 KAT8 regulatory NSL complex subunit 1 -2.27406
HDHD3 haloacid dehalogenase-like hydrolase domain containing 3 -2.27283
DDB2 damage-specific DNA binding protein 2, 48kDa -2.2661
RMI1 RecQ mediated genome instability 1 -2.25874
PGM1 phosphoglucomutase 1 -2.25815
NDUFB6 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 6, 17kDa -2.25751
TPX2 TPX2, microtubule-associated -2.25738
DEPDC1 DEP domain containing 1 -2.24474
SULT2A1 sulfotransferase family, cytosolic, 2A, dehydroepiandrosterone (DHEA)-preferring, member 1 -2.24258
TBC1D10C TBC1 domain family, member 10C -2.23561
SLC35H1 solute carrier family 35 member H1 -2.23561
FAM216A family with sequence similarity 216, member A -2.23493
TOPBP1 topoisomerase (DNA) II binding protein 1 -2.23106
HPD 4-hydroxyphenylpyruvate dioxygenase -2.2281
CPNE3 copine III -2.22661
MRPS16 mitochondrial ribosomal protein S16 -2.22621
TFAM transcription factor A, mitochondrial -2.2255
COQ6 coenzyme Q6 monooxygenase -2.22314
HOXA10 homeobox A10 -2.22266
TARP TCR gamma alternate reading frame protein -2.22254
NISCH nischarin -2.22037
SUPT16H suppressor of Ty 16 homolog (S. cerevisiae) -2.2183
PBK PDZ binding kinase -2.21738
ADH5 alcohol dehydrogenase 5 (class III), chi polypeptide -2.20837
MIS18A MIS18 kinetochore protein A -2.20772
ZBTB35 zinc finger and BTB domain containing 35 -2.20726
EPM2AIP1 EPM2A (laforin) interacting protein 1 -2.20719
MRFAP1L1 Morf4 family associated protein 1-like 1 -2.20601
MIS12 MIS12 kinetochore complex component -2.20201
MCM3 minichromosome maintenance complex component 3 -2.19468
NLRP2B NLR family pyrin domain containing 2B -2.19349
APOM apolipoprotein M -2.19064
DET1 de-etiolated homolog 1 (Arabidopsis) -2.18914
ESPL1 extra spindle pole bodies homolog 1 (S. cerevisiae) -2.18645
RFC3 replication factor C (activator 1) 3, 38kDa -2.18149
RXRA retinoid X receptor, alpha -2.17956
DNA2 DNA replication helicase/nuclease 2 -2.17951
ATP10D ATPase, class V, type 10D -2.17314
CKS1B CDC28 protein kinase regulatory subunit 1B -2.16912
BBS10 Bardet-Biedl syndrome 10 -2.16821
POLE3 polymerase (DNA directed), epsilon 3, accessory subunit -2.16694
C2CD5 C2 calcium-dependent domain containing 5 -2.16443
GMPR2 guanosine monophosphate reductase 2 -2.16078
TIMM8A translocase of inner mitochondrial membrane 8 homolog A (yeast) -2.15747
ARL6IP1 ADP-ribosylation factor-like 6 interacting protein 1 -2.15509
CDT1 chromatin licensing and DNA replication factor 1 -2.15362
SORL1 sortilin-related receptor, L(DLR class) A repeats containing -2.15178
EFNA4 ephrin-A4 -2.14458
MLH1 mutL homolog 1 -2.14114
TMEM38B transmembrane protein 38B -2.13868
PRC1 protein regulator of cytokinesis 1 -2.13358
CUTC cutC copper transporter -2.1313
TFB2M transcription factor B2, mitochondrial -2.13026
SUV39H1 suppressor of variegation 3-9 homolog 1 (Drosophila) -2.12859
PEX11B peroxisomal biogenesis factor 11 beta -2.12852
OIP5 Opa interacting protein 5 -2.12734
PSIP1 PC4 and SFRS1 interacting protein 1 -2.12509
MPHOSPH9 M-phase phosphoprotein 9 -2.1208
CHEK2 checkpoint kinase 2 -2.11941
ATAD2 ATPase family, AAA domain containing 2 -2.11648
NCOA4 nuclear receptor coactivator 4 -2.10828
CXCR3 chemokine (C-X-C motif) receptor 3 -2.10822
CD2 CD2 molecule -2.09659
GMCL1 germ cell-less, spermatogenesis associated 1 -2.09356
CENPS-CORT CENPS-CORT readthrough -2.09235
GCDH glutaryl-CoA dehydrogenase -2.08486
CSTF1 cleavage stimulation factor, 3' pre-RNA, subunit 1, 50kDa -2.08446
PUS1 pseudouridylate synthase 1 -2.08262
LOC124900388 uncharacterized LOC124900388 -2.08119
SRP54 signal recognition particle 54kDa -2.07717
MBIP MAP3K12 binding inhibitory protein 1 -2.07328
PIK3R1 phosphoinositide-3-kinase, regulatory subunit 1 (alpha) -2.06884
CRTAM cytotoxic and regulatory T cell molecule -2.06659
MRPS18B mitochondrial ribosomal protein S18B -2.06642
TMEM258 transmembrane protein 258 -2.06524
ZWINT ZW10 interacting kinetochore protein -2.0641
CDKN1B cyclin-dependent kinase inhibitor 1B (p27, Kip1) -2.06401
CKAP2 cytoskeleton associated protein 2 -2.06037
NPC2 Niemann-Pick disease, type C2 -2.05983
ALG6 ALG6, alpha-1,3-glucosyltransferase -2.05805
RBM14-RBM4 RBM14-RBM4 readthrough -2.0524
HJURP Holliday junction recognition protein -2.05138
LDHD lactate dehydrogenase D -2.04987
TRMT61B tRNA methyltransferase 61B -2.04347
HSD17B11 hydroxysteroid (17-beta) dehydrogenase 11 -2.04289
MRPS14 mitochondrial ribosomal protein S14 -2.042
PM20D1 peptidase M20 domain containing 1 -2.04154
NNT nicotinamide nucleotide transhydrogenase -2.0371
CISD1 CDGSH iron sulfur domain 1 -2.03289
THYN1 thymocyte nuclear protein 1 -2.03259
KDM3A lysine (K)-specific demethylase 3A -2.03177
ACY1 aminoacylase 1 -2.03005
GOLGA4 golgin A4 -2.02905
GLDC glycine dehydrogenase (decarboxylating) -2.02674
THAP10 THAP domain containing 10 -2.02602
MTTP microsomal triglyceride transfer protein -2.02574
MS4A6A membrane-spanning 4-domains, subfamily A, member 6A -2.02216
F2R coagulation factor II (thrombin) receptor -2.02111
SPC25 SPC25, NDC80 kinetochore complex component -2.01896
LSM4 LSM4 homolog, U6 small nuclear RNA associated (S. cerevisiae) -2.01832
GET1 guided entry of tail-anchored proteins factor 1 -2.01668
ZDHHC6 zinc finger, DHHC-type containing 6 -2.0143
TCEAL4 transcription elongation factor A (SII)-like 4 -2.01104
MRPS33 mitochondrial ribosomal protein S33 -2.00975
BCHE butyrylcholinesterase -2.00767
GTF2A2 general transcription factor IIA, 2, 12kDa -2.00712
AGMAT agmatine ureohydrolase (agmatinase) -2.00646
TMPO thymopoietin -2.00592
SSR2 signal sequence receptor, beta (translocon-associated protein beta) -2.00552
HSPA1A heat shock 70kDa protein 1A -2.00466
POLR3K polymerase (RNA) III (DNA directed) polypeptide K, 12.3 kDa -2.00363
BET1 Bet1 golgi vesicular membrane trafficking protein -2.0002