CRCGN017_MCF10A.TP53.M_24H:E14 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description emodin 16.83 um perturbation at 24 h in MCF10A.TP53.M (Carcinogenome)
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Genes

554 genes differentially expressed following the CRCGN017_MCF10A.TP53.M_24H:E14 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
MTHFD2 methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase 8.65657
GLRX glutaredoxin (thioltransferase) 7.49252
GFPT1 glutamine--fructose-6-phosphate transaminase 1 7.43685
AARS1 alanyl-tRNA synthetase 1 6.90211
PCK2 phosphoenolpyruvate carboxykinase 2 (mitochondrial) 6.70944
UGDH UDP-glucose 6-dehydrogenase 6.36512
NUCB2 nucleobindin 2 6.19354
TRIB3 tribbles pseudokinase 3 6.08148
GARS1 glycyl-tRNA synthetase 1 5.57773
ATF4 activating transcription factor 4 5.51649
VSIG2 V-set and immunoglobulin domain containing 2 5.19786
ASNS asparagine synthetase (glutamine-hydrolyzing) 5.17998
CHAC1 ChaC glutathione-specific gamma-glutamylcyclotransferase 1 5.10676
HYOU1 hypoxia up-regulated 1 5.03256
CXCL2 chemokine (C-X-C motif) ligand 2 5.02065
LOC128125814 uncharacterized LOC128125814 4.98858
XPOT exportin, tRNA 4.8713
PYCR1 pyrroline-5-carboxylate reductase 1 4.78318
SLC1A4 solute carrier family 1 (glutamate/neutral amino acid transporter), member 4 4.71784
WIF1 WNT inhibitory factor 1 4.66074
NLRP4 NLR family, pyrin domain containing 4 4.43671
CCNA1 cyclin A1 4.36089
POLD4 polymerase (DNA-directed), delta 4, accessory subunit 4.34577
PSAT1 phosphoserine aminotransferase 1 4.27621
SHMT2 serine hydroxymethyltransferase 2 (mitochondrial) 4.23498
PHGDH phosphoglycerate dehydrogenase 4.1676
KCTD5 potassium channel tetramerization domain containing 5 4.1655
ABHD4 abhydrolase domain containing 4 4.16313
IL1B interleukin 1, beta 4.13957
AGR2 anterior gradient 2 4.11626
SLC3A2 solute carrier family 3 (amino acid transporter heavy chain), member 2 4.11162
SLC7A11 solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 4.04498
CHIC2 cysteine-rich hydrophobic domain 2 4.04434
CTSL cathepsin L 4.03324
CARS1 cysteinyl-tRNA synthetase 1 4.00143
GRB10 growth factor receptor-bound protein 10 3.95989
EHHADH enoyl-CoA, hydratase/3-hydroxyacyl CoA dehydrogenase 3.87477
PRAF2 PRA1 domain family, member 2 3.8594
P4HA2 prolyl 4-hydroxylase, alpha polypeptide II 3.8499
DNAJB2 DnaJ (Hsp40) homolog, subfamily B, member 2 3.80971
IFRD1 interferon-related developmental regulator 1 3.79212
ARHGEF2 Rho/Rac guanine nucleotide exchange factor (GEF) 2 3.69068
EIF4EBP1 eukaryotic translation initiation factor 4E binding protein 1 3.6666
DDX10 DEAD (Asp-Glu-Ala-Asp) box polypeptide 10 3.64406
SLC35A3 solute carrier family 35 (UDP-N-acetylglucosamine (UDP-GlcNAc) transporter), member A3 3.62753
TXNRD1 thioredoxin reductase 1 3.61869
HMGCL 3-hydroxymethyl-3-methylglutaryl-CoA lyase 3.60501
TRIM13 tripartite motif containing 13 3.60294
MANF mesencephalic astrocyte-derived neurotrophic factor 3.56478
TES testin LIM domain protein 3.53402
ECH1 enoyl CoA hydratase 1, peroxisomal 3.49666
PDGFA platelet-derived growth factor alpha polypeptide 3.49539
CRELD2 cysteine-rich with EGF-like domains 2 3.44526
HMOX1 heme oxygenase 1 3.41509
WFS1 Wolfram syndrome 1 (wolframin) 3.40215
ST6GALNAC2 ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2 3.38096
SARS1 seryl-tRNA synthetase 1 3.37456
CTBS chitobiase, di-N-acetyl- 3.36687
ARCN1 archain 1 3.33502
FYN FYN proto-oncogene, Src family tyrosine kinase 3.32494
HSPA5 heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) 3.32032
YARS1 tyrosyl-tRNA synthetase 1 3.31704
ALAS1 5'-aminolevulinate synthase 1 3.29468
AXIN1 axin 1 3.28633
HERPUD1 homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 3.27206
GARRE1 granule associated Rac and RHOG effector 1 3.25244
SQSTM1 sequestosome 1 3.2121
DECR1 2,4-dienoyl CoA reductase 1, mitochondrial 3.20574
MNAT1 MNAT CDK-activating kinase assembly factor 1 3.2054
IGFBP1 insulin-like growth factor binding protein 1 3.14786
RTCA RNA 3'-terminal phosphate cyclase 3.1361
P3H1 prolyl 3-hydroxylase 1 3.12786
NLRX1 NLR family member X1 3.12333
GTPBP2 GTP binding protein 2 3.11115
EDEM1 ER degradation enhancer, mannosidase alpha-like 1 3.08945
QSOX1 quiescin Q6 sulfhydryl oxidase 1 3.07802
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 3.04138
MORC4 MORC family CW-type zinc finger 4 3.03419
RPN1 ribophorin I 2.98094
DNAJB9 DnaJ (Hsp40) homolog, subfamily B, member 9 2.97546
INHBE inhibin, beta E 2.97362
CXCL3 chemokine (C-X-C motif) ligand 3 2.95512
SLC35B1 solute carrier family 35, member B1 2.95239
CEBPG CCAAT/enhancer binding protein (C/EBP), gamma 2.95005
SLC2A10 solute carrier family 2 (facilitated glucose transporter), member 10 2.93416
WARS1 tryptophanyl-tRNA synthetase 1 2.92162
AMZ2 archaelysin family metallopeptidase 2 2.92147
BDNF brain-derived neurotrophic factor 2.91686
IBTK inhibitor of Bruton agammaglobulinemia tyrosine kinase 2.89503
P3H2 prolyl 3-hydroxylase 2 2.89238
USO1 USO1 vesicle transport factor 2.88165
MARS1 methionyl-tRNA synthetase 1 2.8768
MYO18A myosin XVIIIA 2.87623
CABYR calcium binding tyrosine-(Y)-phosphorylation regulated 2.86835
HBA1 hemoglobin, alpha 1 2.86243
COPB1 coatomer protein complex, subunit beta 1 2.85708
TERF2IP telomeric repeat binding factor 2, interacting protein 2.85215
ACTMAP actin maturation protease 2.84154
MID1IP1 MID1 interacting protein 1 2.83453
STC2 stanniocalcin 2 2.8252
GAA glucosidase, alpha; acid 2.82294
RPS6KA2 ribosomal protein S6 kinase, 90kDa, polypeptide 2 2.81992
PDIA4 protein disulfide isomerase family A, member 4 2.8146
SNX6 sorting nexin 6 2.76509
FGFR4 fibroblast growth factor receptor 4 2.7634
NIT1 nitrilase 1 2.74264
CHMP4B charged multivesicular body protein 4B 2.74163
NDEL1 nudE neurodevelopment protein 1-like 1 2.71852
PTPRE protein tyrosine phosphatase, receptor type, E 2.71005
CETN3 centrin, EF-hand protein, 3 2.69932
LCMT1 leucine carboxyl methyltransferase 1 2.68168
LARP6 La ribonucleoprotein domain family, member 6 2.66092
CRAT carnitine O-acetyltransferase 2.65887
CDPF1 cysteine-rich, DPF motif domain containing 1 2.64509
PHF21A PHD finger protein 21A 2.63588
CMAS cytidine monophosphate N-acetylneuraminic acid synthetase 2.63277
SYNGAP1 synaptic Ras GTPase activating protein 1 2.62231
LETMD1 LETM1 domain containing 1 2.60343
METTL25B methyltransferase like 25B 2.59926
G0S2 G0/G1 switch 2 2.59922
ECM1 extracellular matrix protein 1 2.59754
OARD1 O-acyl-ADP-ribose deacylase 1 2.59197
SCFD1 sec1 family domain containing 1 2.58931
KCTD13 potassium channel tetramerization domain containing 13 2.57197
CALU calumenin 2.57151
TTC17 tetratricopeptide repeat domain 17 2.56759
GMPPA GDP-mannose pyrophosphorylase A 2.5647
EGR1 early growth response 1 2.56426
WIPI1 WD repeat domain, phosphoinositide interacting 1 2.56185
TARS1 threonyl-tRNA synthetase 1 2.56126
MOK MOK protein kinase 2.54923
GNE glucosamine (UDP-N-acetyl)-2-epimerase/N-acetylmannosamine kinase 2.54673
CASK calcium/calmodulin-dependent serine protein kinase (MAGUK family) 2.53749
RBCK1 RanBP-type and C3HC4-type zinc finger containing 1 2.52374
DDAH1 dimethylarginine dimethylaminohydrolase 1 2.52101
NDE1 nudE neurodevelopment protein 1 2.51467
SUV39H1 suppressor of variegation 3-9 homolog 1 (Drosophila) 2.50904
CANT1 calcium activated nucleotidase 1 2.50352
PROCR protein C receptor, endothelial 2.49406
ITGA5 integrin, alpha 5 (fibronectin receptor, alpha polypeptide) 2.48598
DRAP1 DR1-associated protein 1 (negative cofactor 2 alpha) 2.47658
CCDC90B coiled-coil domain containing 90B 2.47594
KCMF1 potassium channel modulatory factor 1 2.47382
CDK2AP2 cyclin-dependent kinase 2 associated protein 2 2.47111
IFT88 intraflagellar transport 88 2.46987
SEC24C SEC24 family member C 2.46338
CSGALNACT2 chondroitin sulfate N-acetylgalactosaminyltransferase 2 2.46176
ELF5 E74-like factor 5 (ets domain transcription factor) 2.45169
CAMTA2 calmodulin binding transcription activator 2 2.43534
PLCD1 phospholipase C, delta 1 2.43495
MAP4 microtubule-associated protein 4 2.43494
SIL1 SIL1 nucleotide exchange factor 2.43262
UPP1 uridine phosphorylase 1 2.42659
MTIF2 mitochondrial translational initiation factor 2 2.42401
STX5 syntaxin 5 2.42037
R3HDM2 R3H domain containing 2 2.41983
NGLY1 N-glycanase 1 2.41528
NMRK1 nicotinamide riboside kinase 1 2.41508
PIGP phosphatidylinositol glycan anchor biosynthesis, class P 2.40693
STXBP1 syntaxin binding protein 1 2.40141
CAPRIN2 caprin family member 2 2.38873
NOTCH2NLB notch 2 N-terminal like B 2.37897
MSH5 mutS homolog 5 2.37104
SPANXB1 SPANX family, member B1 2.36672
MKRN1 makorin ring finger protein 1 2.36053
CRELD1 cysteine-rich with EGF-like domains 1 2.34315
HSP90B1 heat shock protein 90kDa beta (Grp94), member 1 2.33484
TGIF1 TGFB-induced factor homeobox 1 2.33246
CDK5RAP3 CDK5 regulatory subunit associated protein 3 2.32092
FAM114A1 family with sequence similarity 114, member A1 2.31828
IFI6 interferon, alpha-inducible protein 6 2.31587
PDIA6 protein disulfide isomerase family A, member 6 2.30052
BET1 Bet1 golgi vesicular membrane trafficking protein 2.29998
DDIT4 DNA-damage-inducible transcript 4 2.29376
RPH3AL rabphilin 3A-like (without C2 domains) 2.28732
COCH cochlin 2.28659
LPGAT1 lysophosphatidylglycerol acyltransferase 1 2.28637
NPIPB5 nuclear pore complex interacting protein family, member B5 2.28279
SLC1A5 solute carrier family 1 (neutral amino acid transporter), member 5 2.27755
ATOSB atos homolog B 2.27324
MICAL1 microtubule associated monooxygenase, calponin and LIM domain containing 1 2.26833
SLC6A1 solute carrier family 6 (neurotransmitter transporter), member 1 2.2675
AP1G1 adaptor-related protein complex 1, gamma 1 subunit 2.26495
SLC16A4 solute carrier family 16, member 4 2.26375
RAB11FIP5 RAB11 family interacting protein 5 (class I) 2.26085
RCN3 reticulocalbin 3, EF-hand calcium binding domain 2.25709
GSTZ1 glutathione S-transferase zeta 1 2.25086
SLC67A1 solute carrier family 67 member 1 2.23627
FHL2 four and a half LIM domains 2 2.23591
PHKA1 phosphorylase kinase, alpha 1 (muscle) 2.23558
NPAS2 neuronal PAS domain protein 2 2.22968
HDLBP high density lipoprotein binding protein 2.22885
HBEGF heparin-binding EGF-like growth factor 2.22781
NFE2L1 nuclear factor, erythroid 2-like 1 2.2238
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) 2.22233
ANKRD11 ankyrin repeat domain 11 2.21944
RNF103 ring finger protein 103 2.21427
PGM3 phosphoglucomutase 3 2.21252
STAMBP STAM binding protein 2.208
PIGV phosphatidylinositol glycan anchor biosynthesis, class V 2.20604
MFGE8 milk fat globule-EGF factor 8 protein 2.20012
GID4 GID complex subunit 4 2.19818
LOC102724560 cystathionine beta-synthase 2.19499
HAX1 HCLS1 associated protein X-1 2.19457
CALCOCO2 calcium binding and coiled-coil domain 2 2.19439
PYGB phosphorylase, glycogen; brain 2.19374
CCNG2 cyclin G2 2.19128
HERC6 HECT and RLD domain containing E3 ubiquitin protein ligase family member 6 2.18632
HS1BP3 HCLS1 binding protein 3 2.17911
FXR2 fragile X mental retardation, autosomal homolog 2 2.17849
IFT20 intraflagellar transport 20 2.17576
SEC61G Sec61 gamma subunit 2.16769
HOXC10 homeobox C10 2.16523
IMPA1 inositol(myo)-1(or 4)-monophosphatase 1 2.16508
MAP1S microtubule-associated protein 1S 2.16482
LYRM1 LYR motif containing 1 2.16297
GDI1 GDP dissociation inhibitor 1 2.1619
TBCB tubulin folding cofactor B 2.16113
NRDC nardilysin convertase 2.14588
RCN1 reticulocalbin 1, EF-hand calcium binding domain 2.13841
EPN2 epsin 2 2.13298
ASS1 argininosuccinate synthase 1 2.13008
PLIN2 perilipin 2 2.12973
FAH fumarylacetoacetate hydrolase (fumarylacetoacetase) 2.12079
ARHGAP29 Rho GTPase activating protein 29 2.11231
RRAS related RAS viral (r-ras) oncogene homolog 2.1112
ACADVL acyl-CoA dehydrogenase, very long chain 2.10788
MAOB monoamine oxidase B 2.10146
MAP2K5 mitogen-activated protein kinase kinase 5 2.10099
NARS1 asparaginyl-tRNA synthetase 1 2.10012
SLC37A4 solute carrier family 37 (glucose-6-phosphate transporter), member 4 2.09867
GNA15 guanine nucleotide binding protein (G protein), alpha 15 (Gq class) 2.09706
PENK proenkephalin 2.08975
IARS1 isoleucyl-tRNA synthetase 1 2.08932
CDK7 cyclin-dependent kinase 7 2.0856
SRP54 signal recognition particle 54kDa 2.08364
H1-0 H1.0 linker histone 2.07531
ETHE1 ethylmalonic encephalopathy 1 2.07053
SARAF store-operated calcium entry-associated regulatory factor 2.07022
UBE2L6 ubiquitin-conjugating enzyme E2L 6 2.06964
PIPOX pipecolic acid oxidase 2.06914
IER3 immediate early response 3 2.06668
KDELR3 KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 3 2.06359
OLAH oleoyl-ACP hydrolase 2.05946
KIFBP kinesin family binding protein 2.05625
TRIP12 thyroid hormone receptor interactor 12 2.05388
ADGRG2 adhesion G protein-coupled receptor G2 2.04668
TXLNA taxilin alpha 2.04382
S100P S100 calcium binding protein P 2.04257
GCC1 GRIP and coiled-coil domain containing 1 2.04214
FKBP11 FK506 binding protein 11, 19 kDa 2.04016
EFEMP2 EGF containing fibulin-like extracellular matrix protein 2 2.03449
RAB5B RAB5B, member RAS oncogene family 2.03383
ZRSR2 zinc finger (CCCH type), RNA-binding motif and serine/arginine rich 2 2.03275
COPZ2 coatomer protein complex, subunit zeta 2 2.02876
MUC2 mucin 2, oligomeric mucus/gel-forming 2.0284
GALE UDP-galactose-4-epimerase 2.02723
ZFAND1 zinc finger, AN1-type domain 1 2.02569
DHRS4 dehydrogenase/reductase (SDR family) member 4 2.02083
AKTIP AKT interacting protein 2.01889
MYDGF myeloid-derived growth factor 2.01885
ULBP2 UL16 binding protein 2 2.01696
SERPINB6 serpin peptidase inhibitor, clade B (ovalbumin), member 6 2.01535
SRGN serglycin 2.01032
NUPR1 nuclear protein, transcriptional regulator, 1 2.00496

decreased expression

Symbol Name Standardized Value
HOXA5 homeobox A5 -7.7524
S100A4 S100 calcium binding protein A4 -7.03515
HACD3 3-hydroxyacyl-CoA dehydratase 3 -5.3149
INSIG1 insulin induced gene 1 -5.09296
STMN1 stathmin 1 -4.79729
TMEM50A transmembrane protein 50A -4.58533
MCM3 minichromosome maintenance complex component 3 -4.49757
SH3D19 SH3 domain containing 19 -4.42999
COG2 component of oligomeric golgi complex 2 -4.16814
BID BH3 interacting domain death agonist -4.0264
HAT1 histone acetyltransferase 1 -3.99202
NSDHL NAD(P) dependent steroid dehydrogenase-like -3.98242
CDK4 cyclin-dependent kinase 4 -3.86125
UQCR10 ubiquinol-cytochrome c reductase, complex III subunit X -3.7756
TUBB6 tubulin, beta 6 class V -3.73473
SLC2A6 solute carrier family 2 (facilitated glucose transporter), member 6 -3.73297
DNMT1 DNA (cytosine-5-)-methyltransferase 1 -3.71507
HSPB1 heat shock 27kDa protein 1 -3.70475
PRR15L proline rich 15-like -3.70126
ZNF274 zinc finger protein 274 -3.69678
OAT ornithine aminotransferase -3.66505
SRSF2 serine/arginine-rich splicing factor 2 -3.60882
HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) -3.59377
HOXA4 homeobox A4 -3.55675
PAFAH1B3 platelet-activating factor acetylhydrolase 1b, catalytic subunit 3 (29kDa) -3.53891
ZDHHC6 zinc finger, DHHC-type containing 6 -3.51027
AKT1 v-akt murine thymoma viral oncogene homolog 1 -3.41986
SRSF3 serine/arginine-rich splicing factor 3 -3.40325
URB2 URB2 ribosome biogenesis 2 homolog (S. cerevisiae) -3.36735
MYBL2 v-myb avian myeloblastosis viral oncogene homolog-like 2 -3.34807
CPNE3 copine III -3.2917
LCMT2 leucine carboxyl methyltransferase 2 -3.21874
FEN1 flap structure-specific endonuclease 1 -3.18229
MRTO4 mRNA turnover 4 homolog (S. cerevisiae) -3.14588
CDC45 cell division cycle 45 -3.13827
RFC2 replication factor C (activator 1) 2, 40kDa -3.12037
WDR77 WD repeat domain 77 -3.11025
MCMBP minichromosome maintenance complex binding protein -3.09641
GRWD1 glutamate-rich WD repeat containing 1 -3.08855
MSMO1 methylsterol monooxygenase 1 -3.0863
RBMS1 RNA binding motif, single stranded interacting protein 1 -3.08495
S100A8 S100 calcium binding protein A8 -3.06237
ANXA2 annexin A2 -3.05185
COX16 COX16 cytochrome c oxidase assembly homolog (S. cerevisiae) -3.04243
GTF3C4 general transcription factor IIIC, polypeptide 4, 90kDa -3.04114
NUP160 nucleoporin 160kDa -3.0211
TMEM109 transmembrane protein 109 -3.01714
PMM2 phosphomannomutase 2 -3.00031
AMDHD2 amidohydrolase domain containing 2 -2.98617
CA9 carbonic anhydrase IX -2.95073
MEIS1 Meis homeobox 1 -2.93936
PRKCD protein kinase C, delta -2.93684
NUP62 nucleoporin 62kDa -2.931
BZW2 basic leucine zipper and W2 domains 2 -2.93043
PGC progastricsin (pepsinogen C) -2.92217
RRP1B ribosomal RNA processing 1B -2.91986
COA7 cytochrome c oxidase assembly factor 7 (putative) -2.91729
CDK20 cyclin-dependent kinase 20 -2.90623
VPS26C VPS26 endosomal protein sorting factor C -2.86802
MCM6 minichromosome maintenance complex component 6 -2.8412
TIMM10B translocase of inner mitochondrial membrane 10 homolog B (yeast) -2.83863
GTF3C5 general transcription factor IIIC, polypeptide 5, 63kDa -2.83364
DSG2 desmoglein 2 -2.83148
DYNLT3 dynein, light chain, Tctex-type 3 -2.82809
MREG melanoregulin -2.82612
RFC3 replication factor C (activator 1) 3, 38kDa -2.82175
MRPS7 mitochondrial ribosomal protein S7 -2.81288
TCEA2 transcription elongation factor A (SII), 2 -2.78978
SZRD1 SUZ RNA binding domain containing 1 -2.78784
CRYZ crystallin, zeta (quinone reductase) -2.78584
LRIG1 leucine-rich repeats and immunoglobulin-like domains 1 -2.78353
LGALS14 lectin, galactoside-binding, soluble, 14 -2.77746
NLRP2B NLR family pyrin domain containing 2B -2.77192
SNRNP25 small nuclear ribonucleoprotein 25kDa (U11/U12) -2.77136
TOE1 target of EGR1, member 1 (nuclear) -2.77061
DHX9 DEAH (Asp-Glu-Ala-His) box helicase 9 -2.75115
CD320 CD320 molecule -2.7493
PPP4R3B protein phosphatase 4 regulatory subunit 3B -2.748
ADI1 acireductone dioxygenase 1 -2.74631
ANKRD10 ankyrin repeat domain 10 -2.7297
DDX19A DEAD (Asp-Glu-Ala-Asp) box polypeptide 19A -2.72481
HMGCR 3-hydroxy-3-methylglutaryl-CoA reductase -2.72404
SREBF1 sterol regulatory element binding transcription factor 1 -2.71452
PSMB3 proteasome (prosome, macropain) subunit, beta type, 3 -2.70966
CYCS cytochrome c, somatic -2.7076
NOP16 NOP16 nucleolar protein -2.70583
GTF3C2 general transcription factor IIIC, polypeptide 2, beta 110kDa -2.70276
GINS3 GINS complex subunit 3 (Psf3 homolog) -2.69207
GGA2 golgi-associated, gamma adaptin ear containing, ARF binding protein 2 -2.68262
MRPL44 mitochondrial ribosomal protein L44 -2.67652
UMPS uridine monophosphate synthetase -2.67309
ILK integrin-linked kinase -2.67057
DHX29 DEAH (Asp-Glu-Ala-His) box polypeptide 29 -2.66289
SYPL1 synaptophysin-like 1 -2.65891
POLR2L polymerase (RNA) II (DNA directed) polypeptide L, 7.6kDa -2.65555
PRPF31 pre-mRNA processing factor 31 -2.65039
CCDC86 coiled-coil domain containing 86 -2.64866
PGAM4 phosphoglycerate mutase family member 4 -2.64777
DHFR dihydrofolate reductase -2.64488
MCM4 minichromosome maintenance complex component 4 -2.64015
DFFB DNA fragmentation factor, 40kDa, beta polypeptide (caspase-activated DNase) -2.63553
ATP5MC3 ATP synthase membrane subunit c locus 3 -2.62468
FAT2 FAT atypical cadherin 2 -2.62222
ITGAE integrin, alpha E (antigen CD103, human mucosal lymphocyte antigen 1; alpha polypeptide) -2.61974
DAG1 dystroglycan 1 (dystrophin-associated glycoprotein 1) -2.61053
MFN2 mitofusin 2 -2.58893
ANP32A acidic (leucine-rich) nuclear phosphoprotein 32 family, member A -2.58473
POLE3 polymerase (DNA directed), epsilon 3, accessory subunit -2.56881
KRT14 keratin 14, type I -2.55836
NUP85 nucleoporin 85kDa -2.5531
TFAM transcription factor A, mitochondrial -2.54877
BRCC3 BRCA1/BRCA2-containing complex, subunit 3 -2.54506
GTF2A2 general transcription factor IIA, 2, 12kDa -2.54025
CIAPIN1 cytokine induced apoptosis inhibitor 1 -2.53028
BIRC5 baculoviral IAP repeat containing 5 -2.52798
RFC5 replication factor C (activator 1) 5, 36.5kDa -2.52541
NELFCD negative elongation factor complex member C/D -2.52276
PFDN1 prefoldin subunit 1 -2.51077
TMEM14A transmembrane protein 14A -2.4938
PMPCA peptidase (mitochondrial processing) alpha -2.48985
LIPF lipase, gastric -2.47726
UBR7 ubiquitin protein ligase E3 component n-recognin 7 (putative) -2.4659
ARFIP2 ADP-ribosylation factor interacting protein 2 -2.46007
SRRM1 serine/arginine repetitive matrix 1 -2.45875
TMEM51 transmembrane protein 51 -2.45745
NUSAP1 nucleolar and spindle associated protein 1 -2.45326
DCK deoxycytidine kinase -2.44795
FKBP5 FK506 binding protein 5 -2.44772
LOC128966601 pyruvate dehydrogenase phosphatase regulatory subunit, mitochondrial-like -2.44692
PGRMC1 progesterone receptor membrane component 1 -2.44585
ZNF207 zinc finger protein 207 -2.44466
LYRM2 LYR motif containing 2 -2.44368
METTL16 methyltransferase like 16 -2.44143
ELOVL6 ELOVL fatty acid elongase 6 -2.43567
PPP1R17 protein phosphatase 1, regulatory subunit 17 -2.43204
BAG3 BCL2-associated athanogene 3 -2.42173
CCDC47 coiled-coil domain containing 47 -2.41958
DNAJC15 DnaJ (Hsp40) homolog, subfamily C, member 15 -2.41919
DNAJC8 DnaJ (Hsp40) homolog, subfamily C, member 8 -2.41785
PRPF4 pre-mRNA processing factor 4 -2.41466
TCERG1 transcription elongation regulator 1 -2.40988
SOAT2 sterol O-acyltransferase 2 -2.40593
PRKAR2B protein kinase, cAMP-dependent, regulatory, type II, beta -2.40582
MCM10 minichromosome maintenance complex component 10 -2.39687
SRSF10 serine/arginine-rich splicing factor 10 -2.3894
PSRC1 proline/serine-rich coiled-coil 1 -2.38227
EIF2B1 eukaryotic translation initiation factor 2B, subunit 1 alpha, 26kDa -2.38171
INTS9 integrator complex subunit 9 -2.37109
PSME3 proteasome (prosome, macropain) activator subunit 3 (PA28 gamma; Ki) -2.36369
SRRT serrate, RNA effector molecule -2.35635
FASTKD5 FAST kinase domains 5 -2.35039
MYO19 myosin XIX -2.35004
SCD stearoyl-CoA desaturase (delta-9-desaturase) -2.34997
GINS2 GINS complex subunit 2 (Psf2 homolog) -2.34518
QTRT2 queuine tRNA-ribosyltransferase accessory subunit 2 -2.33961
GDE1 glycerophosphodiester phosphodiesterase 1 -2.33956
THRAP3 thyroid hormone receptor associated protein 3 -2.337
PYDC1 PYD (pyrin domain) containing 1 -2.31197
ADAM15 ADAM metallopeptidase domain 15 -2.31089
B4GALT5 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 -2.29616
AKT2 v-akt murine thymoma viral oncogene homolog 2 -2.29394
DNAJB1 DnaJ (Hsp40) homolog, subfamily B, member 1 -2.29387
UPF1 UPF1 regulator of nonsense transcripts homolog (yeast) -2.29374
BAG1 BCL2-associated athanogene -2.29335
ASF1B anti-silencing function 1B histone chaperone -2.28665
XRCC5 X-ray repair complementing defective repair in Chinese hamster cells 5 (double-strand-break rejoining) -2.28319
ZBTB24 zinc finger and BTB domain containing 24 -2.27494
POLR3K polymerase (RNA) III (DNA directed) polypeptide K, 12.3 kDa -2.27263
HS3ST2 heparan sulfate (glucosamine) 3-O-sulfotransferase 2 -2.26524
RIC8A RIC8 guanine nucleotide exchange factor A -2.25706
LMBR1 limb development membrane protein 1 -2.25263
PCNA proliferating cell nuclear antigen -2.25119
NDUFS3 NADH dehydrogenase (ubiquinone) Fe-S protein 3, 30kDa (NADH-coenzyme Q reductase) -2.24643
LAPTM4B lysosomal protein transmembrane 4 beta -2.24567
RRM1 ribonucleotide reductase M1 -2.24518
TIMM9 translocase of inner mitochondrial membrane 9 homolog (yeast) -2.24483
SESN1 sestrin 1 -2.23874
CCNC cyclin C -2.23458
APH1A APH1A gamma secretase subunit -2.23137
POLR2K polymerase (RNA) II (DNA directed) polypeptide K, 7.0kDa -2.23048
HNRNPAB heterogeneous nuclear ribonucleoprotein A/B -2.2283
NPDC1 neural proliferation, differentiation and control, 1 -2.22829
SLC5A6 solute carrier family 5 (sodium/multivitamin and iodide cotransporter), member 6 -2.22313
SETMAR SET domain and mariner transposase fusion gene -2.22096
DHCR7 7-dehydrocholesterol reductase -2.22068
CYB5B cytochrome b5 type B (outer mitochondrial membrane) -2.22015
IREB2 iron-responsive element binding protein 2 -2.21793
SMARCC1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 1 -2.21431
YIPF5 Yip1 domain family, member 5 -2.21305
RALGDS ral guanine nucleotide dissociation stimulator -2.21299
ASTE1 asteroid homolog 1 (Drosophila) -2.20943
TMEM43 transmembrane protein 43 -2.20879
TFDP1 transcription factor Dp-1 -2.20667
TIMM8A translocase of inner mitochondrial membrane 8 homolog A (yeast) -2.2049
DBR1 debranching RNA lariats 1 -2.20183
TCTA T-cell leukemia translocation altered -2.19487
JPT2 Jupiter microtubule associated homolog 2 -2.19471
MTOR mechanistic target of rapamycin (serine/threonine kinase) -2.19296
STOML2 stomatin (EPB72)-like 2 -2.19044
NDUFA8 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 8, 19kDa -2.18956
TIMELESS timeless circadian clock -2.18933
GEMIN4 gem (nuclear organelle) associated protein 4 -2.18337
ATP5PB ATP synthase peripheral stalk-membrane subunit b -2.18095
SLC2A9 solute carrier family 2 (facilitated glucose transporter), member 9 -2.17997
STARD7 StAR-related lipid transfer (START) domain containing 7 -2.17963
AP5M1 adaptor-related protein complex 5, mu 1 subunit -2.17534
HDAC3 histone deacetylase 3 -2.17452
CLEC16A C-type lectin domain family 16, member A -2.17426
SNRNP40 small nuclear ribonucleoprotein 40kDa (U5) -2.16987
ANAPC15 anaphase promoting complex subunit 15 -2.16714
TMEM165 transmembrane protein 165 -2.16651
FUS FUS RNA binding protein -2.16431
WWC1 WW and C2 domain containing 1 -2.16404
EXOSC4 exosome component 4 -2.16375
SYNE2 spectrin repeat containing, nuclear envelope 2 -2.16311
CENPM centromere protein M -2.16119
CLUH clustered mitochondria (cluA/CLU1) homolog -2.15697
G3BP1 GTPase activating protein (SH3 domain) binding protein 1 -2.15504
POP5 processing of precursor 5, ribonuclease P/MRP subunit (S. cerevisiae) -2.15301
SS18L2 synovial sarcoma translocation gene on chromosome 18-like 2 -2.15035
CDC40 cell division cycle 40 -2.14929
GGA3 golgi-associated, gamma adaptin ear containing, ARF binding protein 3 -2.14802
CCND3 cyclin D3 -2.14657
CWF19L1 CWF19-like 1, cell cycle control (S. pombe) -2.14581
HTD2 hydroxyacyl-thioester dehydratase type 2 -2.14571
GSTP1 glutathione S-transferase pi 1 -2.14063
KCNA3 potassium channel, voltage gated shaker related subfamily A, member 3 -2.13774
LPCAT3 lysophosphatidylcholine acyltransferase 3 -2.13332
PARP1 poly (ADP-ribose) polymerase 1 -2.13248
PRPF19 pre-mRNA processing factor 19 -2.13234
MRPL11 mitochondrial ribosomal protein L11 -2.13226
SKP1 S-phase kinase-associated protein 1 -2.13136
POLR2H polymerase (RNA) II (DNA directed) polypeptide H -2.12696
KCNK5 potassium channel, two pore domain subfamily K, member 5 -2.11807
FGFBP1 fibroblast growth factor binding protein 1 -2.11735
HDAC2 histone deacetylase 2 -2.11586
SRSF7 serine/arginine-rich splicing factor 7 -2.11219
CISD1 CDGSH iron sulfur domain 1 -2.11179
PBX3 pre-B-cell leukemia homeobox 3 -2.10792
DDX39A DEAD (Asp-Glu-Ala-Asp) box polypeptide 39A -2.10691
EYA4 EYA transcriptional coactivator and phosphatase 4 -2.10438
DKC1 dyskeratosis congenita 1, dyskerin -2.10408
DHCR24 24-dehydrocholesterol reductase -2.10199
CHAF1A chromatin assembly factor 1, subunit A (p150) -2.10129
HSBP1 heat shock factor binding protein 1 -2.10045
ATP4A ATPase, H+/K+ exchanging, alpha polypeptide -2.1003
TTC27 tetratricopeptide repeat domain 27 -2.10018
EHMT1 euchromatic histone-lysine N-methyltransferase 1 -2.09856
MED31 mediator complex subunit 31 -2.09205
HOXA7 homeobox A7 -2.09035
KDM1A lysine (K)-specific demethylase 1A -2.09033
MARCKS myristoylated alanine-rich protein kinase C substrate -2.08969
KBTBD4 kelch repeat and BTB (POZ) domain containing 4 -2.08796
MSL1 male-specific lethal 1 homolog (Drosophila) -2.08546
GTPBP8 GTP-binding protein 8 (putative) -2.0821
P2RY2 purinergic receptor P2Y, G-protein coupled, 2 -2.07754
NUFIP1 nuclear fragile X mental retardation protein interacting protein 1 -2.0756
NAP1L4 nucleosome assembly protein 1-like 4 -2.07523
CUL1 cullin 1 -2.07508
BICD2 bicaudal D homolog 2 (Drosophila) -2.07386
NUBP2 nucleotide binding protein 2 -2.07297
MRPL12 mitochondrial ribosomal protein L12 -2.07049
U2AF2 U2 small nuclear RNA auxiliary factor 2 -2.07017
TNFAIP2 tumor necrosis factor, alpha-induced protein 2 -2.06615
FBXO34 F-box protein 34 -2.05969
MRPS34 mitochondrial ribosomal protein S34 -2.05756
ELAVL2 ELAV like neuron-specific RNA binding protein 2 -2.05705
DCTPP1 dCTP pyrophosphatase 1 -2.05588
MS4A6A membrane-spanning 4-domains, subfamily A, member 6A -2.05508
CPPED1 calcineurin-like phosphoesterase domain containing 1 -2.05277
TNFSF10 tumor necrosis factor (ligand) superfamily, member 10 -2.05198
MRPS27 mitochondrial ribosomal protein S27 -2.05037
ATP1A4 ATPase, Na+/K+ transporting, alpha 4 polypeptide -2.04358
MVD mevalonate (diphospho) decarboxylase -2.04147
NT5DC2 5'-nucleotidase domain containing 2 -2.02875
SYK spleen tyrosine kinase -2.02581
SPRR1B small proline-rich protein 1B -2.02526
MCM7 minichromosome maintenance complex component 7 -2.02373
TKT transketolase -2.02148
RPIA ribose 5-phosphate isomerase A -2.02027
POLA2 polymerase (DNA directed), alpha 2, accessory subunit -2.014
MAFB v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog B -2.01324
FCER2 Fc fragment of IgE, low affinity II, receptor for (CD23) -2.01302
HNRNPA0 heterogeneous nuclear ribonucleoprotein A0 -2.01045
RRP15 ribosomal RNA processing 15 homolog (S. cerevisiae) -2.0083
POLR1G RNA polymerase I subunit G -2.00527
TOPORS topoisomerase I binding, arginine/serine-rich, E3 ubiquitin protein ligase -2.00272
MOCS3 molybdenum cofactor synthesis 3 -2.00086
ST14 suppression of tumorigenicity 14 (colon carcinoma) -2.00051