CRCGN017_MCF10A.TP53.M_24H:E18 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description tetrakis(hydroxymethyl)phos-phonium chloride 11.27 um perturbation at 24 h in MCF10A.TP53.M (Carcinogenome)
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Genes

17 genes differentially expressed following the CRCGN017_MCF10A.TP53.M_24H:E18 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
SSBP2 single-stranded DNA binding protein 2 4.95314
RPL39L ribosomal protein L39-like 3.06299
TOMM34 translocase of outer mitochondrial membrane 34 3.01371
ABHD4 abhydrolase domain containing 4 2.63568
MYLK myosin light chain kinase 2.61146
ACAA1 acetyl-CoA acyltransferase 1 2.25185
STK10 serine/threonine kinase 10 2.00479

decreased expression

Symbol Name Standardized Value
CCDC86 coiled-coil domain containing 86 -5.00144
PCNA proliferating cell nuclear antigen -4.58971
LYPLA1 lysophospholipase I -3.78175
PRPF4 pre-mRNA processing factor 4 -2.65092
ZMYM2 zinc finger, MYM-type 2 -2.62238
SNRPB small nuclear ribonucleoprotein polypeptides B and B1 -2.23581
CSNK2A2 casein kinase 2, alpha prime polypeptide -2.12376
GDF15 growth differentiation factor 15 -2.11068
TENT4A terminal nucleotidyltransferase 4A -2.10094
PANK2 pantothenate kinase 2 -2.04758