CRCGN017_MCF10A.TP53.M_24H:E19 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description triphenylphosphine oxide 96.68 um perturbation at 24 h in MCF10A.TP53.M (Carcinogenome)
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Genes

20 genes differentially expressed following the CRCGN017_MCF10A.TP53.M_24H:E19 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
GNA15 guanine nucleotide binding protein (G protein), alpha 15 (Gq class) 2.69846
CXCR4 chemokine (C-X-C motif) receptor 4 2.58855
HLA-DRA major histocompatibility complex, class II, DR alpha 2.48798
STK10 serine/threonine kinase 10 2.48106
FKBP9 FK506 binding protein 9, 63 kDa 2.35229
TCFL5 transcription factor-like 5 (basic helix-loop-helix) 2.34713

decreased expression

Symbol Name Standardized Value
CHIC2 cysteine-rich hydrophobic domain 2 -4.28177
SCYL3 SCY1-like 3 (S. cerevisiae) -4.20262
IFRD2 interferon-related developmental regulator 2 -2.92219
TMEM115 transmembrane protein 115 -2.74051
TOR1A torsin family 1, member A (torsin A) -2.50109
ADRB2 adrenoceptor beta 2, surface -2.4666
NT5DC2 5'-nucleotidase domain containing 2 -2.40002
PPP2R5E protein phosphatase 2, regulatory subunit B', epsilon isoform -2.38279
APEH acylaminoacyl-peptide hydrolase -2.161
RGS2 regulator of G-protein signaling 2 -2.0665
TCEA2 transcription elongation factor A (SII), 2 -2.0522
FAIM Fas apoptotic inhibitory molecule -2.04136
ATP6V0B ATPase, H+ transporting, lysosomal 21kDa, V0 subunit b -2.02302
MMUT methylmalonyl-CoA mutase -2.01107