CRCGN017_MCF10A.TP53.M_24H:E20 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description triphenylphosphine oxide 32.23 um perturbation at 24 h in MCF10A.TP53.M (Carcinogenome)
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Genes

23 genes differentially expressed following the CRCGN017_MCF10A.TP53.M_24H:E20 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
SNAP25 synaptosomal-associated protein, 25kDa 4.14291
UBQLN2 ubiquilin 2 4.05435
TIMM22 translocase of inner mitochondrial membrane 22 homolog (yeast) 4.04818
BAMBI BMP and activin membrane-bound inhibitor 2.84771
FSD1 fibronectin type III and SPRY domain containing 1 2.74352
CCNF cyclin F 2.62701
BDH1 3-hydroxybutyrate dehydrogenase, type 1 2.4346
GNG3 guanine nucleotide binding protein (G protein), gamma 3 2.1354
INA internexin neuronal intermediate filament protein, alpha 2.08187
STMN2 stathmin 2 2.02967
SV2B synaptic vesicle glycoprotein 2B 2.02962
NSG2 neuronal vesicle trafficking associated 2 2.02766
CEBPD CCAAT/enhancer binding protein (C/EBP), delta 2.02373

decreased expression

Symbol Name Standardized Value
HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) -4.76641
MSMO1 methylsterol monooxygenase 1 -4.68174
HMG20B high mobility group 20B -4.62979
VDAC1 voltage-dependent anion channel 1 -4.09159
DECR1 2,4-dienoyl CoA reductase 1, mitochondrial -3.2089
PPIC peptidylprolyl isomerase C (cyclophilin C) -3.19348
SQLE squalene epoxidase -2.51218
TRIB3 tribbles pseudokinase 3 -2.49979
CYP51A1 cytochrome P450, family 51, subfamily A, polypeptide 1 -2.33371
TMEM267 transmembrane protein 267 -2.28749