CRCGN017_MCF10A.TP53.M_24H:E21 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description triphenylphosphine oxide 10.74 um perturbation at 24 h in MCF10A.TP53.M (Carcinogenome)
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Genes

23 genes differentially expressed following the CRCGN017_MCF10A.TP53.M_24H:E21 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
GNAI1 guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1 4.46013
STAP2 signal transducing adaptor family member 2 3.79293
EDEM1 ER degradation enhancer, mannosidase alpha-like 1 3.38943
ITFG1 integrin alpha FG-GAP repeat containing 1 2.9596
FSD1 fibronectin type III and SPRY domain containing 1 2.67633
HBA1 hemoglobin, alpha 1 2.66146
HBB hemoglobin, beta 2.41669
INPP4B inositol polyphosphate-4-phosphatase, type II, 105kDa 2.3677
GARRE1 granule associated Rac and RHOG effector 1 2.35473
DCXR dicarbonyl/L-xylulose reductase 2.31817
DCUN1D4 DCN1, defective in cullin neddylation 1, domain containing 4 2.23346
APBB2 amyloid beta (A4) precursor protein-binding, family B, member 2 2.10907
BMP4 bone morphogenetic protein 4 2.02977

decreased expression

Symbol Name Standardized Value
COG7 component of oligomeric golgi complex 7 -3.6183
CCNB1 cyclin B1 -3.5103
SCYL3 SCY1-like 3 (S. cerevisiae) -3.11407
PGAM4 phosphoglycerate mutase family member 4 -3.0331
KIF14 kinesin family member 14 -2.95563
CYCS cytochrome c, somatic -2.7172
ZNF652 zinc finger protein 652 -2.46283
RPP38 ribonuclease P/MRP 38kDa subunit -2.3975
UQCR10 ubiquinol-cytochrome c reductase, complex III subunit X -2.17367
ABCC2 ATP-binding cassette, sub-family C (CFTR/MRP), member 2 -2.1142