CRCGN017_MCF10A.TP53.M_24H:E24 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description sodium (e)-4-hydroxy-3-((4-sulfonatonaphthalen-1-yl)diazenyl)naphthalene-1-sulfonate 11.69 um perturbation at 24 h in MCF10A.TP53.M (Carcinogenome)
Similar Terms
Downloads & Tools

Genes

35 genes differentially expressed following the CRCGN017_MCF10A.TP53.M_24H:E24 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
RBP4 retinol binding protein 4, plasma 3.90167
DUSP11 dual specificity phosphatase 11 (RNA/RNP complex 1-interacting) 3.4473
PLCB3 phospholipase C, beta 3 (phosphatidylinositol-specific) 2.99435
PDLIM1 PDZ and LIM domain 1 2.72146
ACAA1 acetyl-CoA acyltransferase 1 2.69437
FOS FBJ murine osteosarcoma viral oncogene homolog 2.42733
GARRE1 granule associated Rac and RHOG effector 1 2.3192
PPARG peroxisome proliferator-activated receptor gamma 2.28855
CCNL1 cyclin L1 2.18328
RRP12 ribosomal RNA processing 12 homolog (S. cerevisiae) 2.14423
MEST mesoderm specific transcript 2.13078
ADGRL4 adhesion G protein-coupled receptor L4 2.08521
DNMT3A DNA (cytosine-5-)-methyltransferase 3 alpha 2.08356
FABP4 fatty acid binding protein 4, adipocyte 2.08249
C5 complement component 5 2.06075
PRCC papillary renal cell carcinoma (translocation-associated) 2.0549
ITFG1 integrin alpha FG-GAP repeat containing 1 2.04762
MED22 mediator complex subunit 22 2.02898
PTPN14 protein tyrosine phosphatase, non-receptor type 14 2.01892
IFNAR1 interferon (alpha, beta and omega) receptor 1 2.01477
UCP1 uncoupling protein 1 (mitochondrial, proton carrier) 2.01066

decreased expression

Symbol Name Standardized Value
CCNB2 cyclin B2 -4.40553
CD81 CD81 molecule -3.97324
PRPF4 pre-mRNA processing factor 4 -3.79847
TM9SF3 transmembrane 9 superfamily member 3 -3.62533
SLC7A5 solute carrier family 7 (amino acid transporter light chain, L system), member 5 -2.87531
RXYLT1 ribitol xylosyltransferase 1 -2.4975
CCNB1 cyclin B1 -2.43563
ZBTB38 zinc finger and BTB domain containing 38 -2.28312
TOMM20 translocase of outer mitochondrial membrane 20 homolog (yeast) -2.21792
RIOK2 RIO kinase 2 -2.07755
UAP1 UDP-N-acetylglucosamine pyrophosphorylase 1 -2.07053
ASXL2 additional sex combs like transcriptional regulator 2 -2.0277
RSRC1 arginine/serine-rich coiled-coil 1 -2.02131
CCSER2 coiled-coil serine-rich protein 2 -2.01671