CRCGN017_MCF10A.TP53.M_24H:F02 Gene Set
Genes
39 genes differentially expressed following the CRCGN017_MCF10A.TP53.M_24H:F02 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
SPAG4
|
sperm associated antigen 4
|
5.0
|
|
HDGFL3
|
HDGF like 3
|
4.15821
|
|
RAC2
|
ras-related C3 botulinum toxin substrate 2 (rho family, small GTP binding protein Rac2)
|
4.05075
|
|
ACAA1
|
acetyl-CoA acyltransferase 1
|
3.4888
|
|
NOL3
|
nucleolar protein 3 (apoptosis repressor with CARD domain)
|
3.1512
|
|
SNCA
|
synuclein, alpha (non A4 component of amyloid precursor)
|
3.02625
|
|
PRR7
|
proline rich 7 (synaptic)
|
2.89225
|
|
IKBKE
|
inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon
|
2.86575
|
|
PACSIN3
|
protein kinase C and casein kinase substrate in neurons 3
|
2.8433
|
|
NUCB2
|
nucleobindin 2
|
2.32545
|
|
ALX1
|
ALX homeobox 1
|
2.28655
|
|
BCKDK
|
branched chain ketoacid dehydrogenase kinase
|
2.25715
|
|
ARFGAP2
|
ADP-ribosylation factor GTPase activating protein 2
|
2.12595
|
|
LYN
|
LYN proto-oncogene, Src family tyrosine kinase
|
2.09802
|
|
BZW2
|
basic leucine zipper and W2 domains 2
|
2.0789
|
|
SLC5A6
|
solute carrier family 5 (sodium/multivitamin and iodide cotransporter), member 6
|
2.03685
|
|
CTBP2
|
C-terminal binding protein 2
|
2.0339
|
|
ZNF26
|
zinc finger protein 26
|
2.0008
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
CAB39
|
calcium binding protein 39
|
-5.60425
|
|
PCNA
|
proliferating cell nuclear antigen
|
-5.5173
|
|
HSPA8
|
heat shock 70kDa protein 8
|
-5.18538
|
|
KRT14
|
keratin 14, type I
|
-5.0
|
|
ADI1
|
acireductone dioxygenase 1
|
-4.7754
|
|
DYNLT3
|
dynein, light chain, Tctex-type 3
|
-4.43845
|
|
RBM34
|
RNA binding motif protein 34
|
-3.45445
|
|
SLC7A5
|
solute carrier family 7 (amino acid transporter light chain, L system), member 5
|
-2.84465
|
|
PSMG1
|
proteasome (prosome, macropain) assembly chaperone 1
|
-2.72095
|
|
EIF3H
|
eukaryotic translation initiation factor 3, subunit H
|
-2.5796
|
|
AATF
|
apoptosis antagonizing transcription factor
|
-2.49815
|
|
TNFRSF21
|
tumor necrosis factor receptor superfamily, member 21
|
-2.37855
|
|
CDS2
|
CDP-diacylglycerol synthase (phosphatidate cytidylyltransferase) 2
|
-2.3443
|
|
XPO7
|
exportin 7
|
-2.22333
|
|
ATIC
|
5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase
|
-2.20825
|
|
BMP2
|
bone morphogenetic protein 2
|
-2.20692
|
|
CIAPIN1
|
cytokine induced apoptosis inhibitor 1
|
-2.1935
|
|
STXBP1
|
syntaxin binding protein 1
|
-2.18675
|
|
MKKS
|
McKusick-Kaufman syndrome
|
-2.0447
|
|
KIZ
|
kizuna centrosomal protein
|
-2.00915
|
|
ZNF165
|
zinc finger protein 165
|
-2.00365
|