CRCGN017_MCF10A.TP53.M_24H:F03 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description beta-carotene 5.67 um perturbation at 24 h in MCF10A.TP53.M (Carcinogenome)
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Genes

35 genes differentially expressed following the CRCGN017_MCF10A.TP53.M_24H:F03 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
TSEN2 TSEN2 tRNA splicing endonuclease subunit 5.08054
ADO 2-aminoethanethiol (cysteamine) dioxygenase 4.79947
SNAP25 synaptosomal-associated protein, 25kDa 4.78851
AGR2 anterior gradient 2 3.79605
ARID5B AT rich interactive domain 5B (MRF1-like) 2.72943
SYN1 synapsin I 2.48556
RXYLT1 ribitol xylosyltransferase 1 2.26593
RPRD1A regulation of nuclear pre-mRNA domain containing 1A 2.14263
CSTF2T cleavage stimulation factor, 3' pre-RNA, subunit 2, 64kDa, tau variant 2.14026
NEFH neurofilament, heavy polypeptide 2.09554
PCDHB11 protocadherin beta 11 2.06436
NRBF2 nuclear receptor binding factor 2 2.06186
GNG3 guanine nucleotide binding protein (G protein), gamma 3 2.06048
GABRA1 gamma-aminobutyric acid (GABA) A receptor, alpha 1 2.059
TMEM168 transmembrane protein 168 2.03387
CMTM6 CKLF-like MARVEL transmembrane domain containing 6 2.00187

decreased expression

Symbol Name Standardized Value
PCNA proliferating cell nuclear antigen -4.15256
TRAPPC3 trafficking protein particle complex 3 -3.86072
SORBS3 sorbin and SH3 domain containing 3 -3.65564
CCNB1 cyclin B1 -3.56136
SLC7A5 solute carrier family 7 (amino acid transporter light chain, L system), member 5 -3.37878
ERBIN erbb2 interacting protein -3.20761
BASP1 brain abundant, membrane attached signal protein 1 -3.14282
SF3A3 splicing factor 3a, subunit 3, 60kDa -3.07073
MRPS15 mitochondrial ribosomal protein S15 -2.88018
SERF1A small EDRK-rich factor 1A (telomeric) -2.6265
SOD1 superoxide dismutase 1, soluble -2.24848
RBM15B RNA binding motif protein 15B -2.16457
LOC102724594 splicing factor U2AF 35 kDa subunit -2.15351
SYTL3 synaptotagmin-like 3 -2.14541
MAP3K8 mitogen-activated protein kinase kinase kinase 8 -2.1045
SERPING1 serpin peptidase inhibitor, clade G (C1 inhibitor), member 1 -2.10432
FHIP2B FHF complex subunit HOOK interacting protein 2B -2.0735
MAP4K4 mitogen-activated protein kinase kinase kinase kinase 4 -2.05793
COL8A2 collagen, type VIII, alpha 2 -2.05215