CRCGN017_MCF10A.TP53.M_24H:F04 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description c.i. acid red 114 101.47 um perturbation at 24 h in MCF10A.TP53.M (Carcinogenome)
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Genes

56 genes differentially expressed following the CRCGN017_MCF10A.TP53.M_24H:F04 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
ALDOC aldolase C, fructose-bisphosphate 5.422
ADO 2-aminoethanethiol (cysteamine) dioxygenase 5.13881
FKBP14 FK506 binding protein 14, 22 kDa 4.73928
TCFL5 transcription factor-like 5 (basic helix-loop-helix) 3.58782
KLHDC2 kelch domain containing 2 3.29774
AGR2 anterior gradient 2 2.9445
FSCN1 fascin actin-bundling protein 1 2.58344
COMP cartilage oligomeric matrix protein 2.52871
SPAG7 sperm associated antigen 7 2.41101
EXTL2 exostosin-like glycosyltransferase 2 2.33173
HMGA2 high mobility group AT-hook 2 2.29172
PTPRZ1 protein tyrosine phosphatase, receptor-type, Z polypeptide 1 2.2835
EMP3 epithelial membrane protein 3 2.26623
ZC3H12A zinc finger CCCH-type containing 12A 2.2176
CSF2 colony stimulating factor 2 (granulocyte-macrophage) 2.20304
SPG11 spastic paraplegia 11 (autosomal recessive) 2.18827
PRAF2 PRA1 domain family, member 2 2.18396
GALE UDP-galactose-4-epimerase 2.17842
TTC38 tetratricopeptide repeat domain 38 2.16408
MICALL1 MICAL-like 1 2.14765
CASP10 caspase 10, apoptosis-related cysteine peptidase 2.10971
GSAP gamma-secretase activating protein 2.0763
TTLL1 tubulin tyrosine ligase-like family member 1 2.03679
CD70 CD70 molecule 2.03008
PRR7 proline rich 7 (synaptic) 2.01627
ZNF518A zinc finger protein 518A 2.00996

decreased expression

Symbol Name Standardized Value
TEX10 testis expressed 10 -4.61142
INPP4B inositol polyphosphate-4-phosphatase, type II, 105kDa -3.96181
ITGAE integrin, alpha E (antigen CD103, human mucosal lymphocyte antigen 1; alpha polypeptide) -3.68778
P2RX5 purinergic receptor P2X, ligand gated ion channel, 5 -3.63317
TXNRD1 thioredoxin reductase 1 -3.49208
PRR15L proline rich 15-like -3.34367
HERC6 HECT and RLD domain containing E3 ubiquitin protein ligase family member 6 -2.98799
YAF2 YY1 associated factor 2 -2.85285
ELAC2 elaC ribonuclease Z 2 -2.72168
DNAJC15 DnaJ (Hsp40) homolog, subfamily C, member 15 -2.59181
ATF5 activating transcription factor 5 -2.54121
RPN1 ribophorin I -2.42602
EPCAM epithelial cell adhesion molecule -2.38944
TACC2 transforming, acidic coiled-coil containing protein 2 -2.35825
RAB25 RAB25, member RAS oncogene family -2.33606
C1QBP complement component 1, q subcomponent binding protein -2.30666
EBNA1BP2 EBNA1 binding protein 2 -2.29324
CDK7 cyclin-dependent kinase 7 -2.25712
CCNC cyclin C -2.23964
SEC61B Sec61 beta subunit -2.16761
KCTD9 potassium channel tetramerization domain containing 9 -2.14395
PSME2 proteasome (prosome, macropain) activator subunit 2 (PA28 beta) -2.10876
RIPPLY2-CYB5R4 RIPPLY2-CYB5R4 readthrough -2.09506
CCL19 chemokine (C-C motif) ligand 19 -2.07667
GTPBP8 GTP-binding protein 8 (putative) -2.07255
LAMP5 lysosomal-associated membrane protein family, member 5 -2.06231
SYBU syntabulin (syntaxin-interacting) -2.01785
GOLT1B golgi transport 1B -2.01339
GMIP GEM interacting protein -2.01067
SYNE2 spectrin repeat containing, nuclear envelope 2 -2.00446