CRCGN017_MCF10A.TP53.M_24H:F07 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description scopolamine hydrobromide tri-hydrate 100.97 um perturbation at 24 h in MCF10A.TP53.M (Carcinogenome)
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Genes

22 genes differentially expressed following the CRCGN017_MCF10A.TP53.M_24H:F07 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
AMDHD2 amidohydrolase domain containing 2 4.86248
ADAM10 ADAM metallopeptidase domain 10 4.17446
FGFR4 fibroblast growth factor receptor 4 4.1027
PNKP polynucleotide kinase 3'-phosphatase 3.8295
ZNF318 zinc finger protein 318 3.60256
OLFML2B olfactomedin-like 2B 2.82125
DPH2 DPH2 homolog (S. cerevisiae) 2.72709
YTHDF1 YTH N(6)-methyladenosine RNA binding protein 1 2.30301
TPD52L2 tumor protein D52-like 2 2.29248
DEAF1 DEAF1 transcription factor 2.16218
PPP1R26 protein phosphatase 1, regulatory subunit 26 2.15435
RBP4 retinol binding protein 4, plasma 2.07445
TCFL5 transcription factor-like 5 (basic helix-loop-helix) 2.06583

decreased expression

Symbol Name Standardized Value
KIF20A kinesin family member 20A -4.9523
KDM3A lysine (K)-specific demethylase 3A -2.86233
SLC7A5 solute carrier family 7 (amino acid transporter light chain, L system), member 5 -2.79624
PIH1D1 PIH1 domain containing 1 -2.77926
PPP2R5E protein phosphatase 2, regulatory subunit B', epsilon isoform -2.65651
ALDH7A1 aldehyde dehydrogenase 7 family, member A1 -2.58938
KRT14 keratin 14, type I -2.4601
RAD51C RAD51 paralog C -2.05125
WNT10B wingless-type MMTV integration site family, member 10B -2.04263