CRCGN017_MCF10A.TP53.M_24H:F08 Gene Set
Genes
64 genes differentially expressed following the CRCGN017_MCF10A.TP53.M_24H:F08 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
AGR2
|
anterior gradient 2
|
5.05553
|
|
CIAO3
|
cytosolic iron-sulfur assembly component 3
|
3.89757
|
|
E2F2
|
E2F transcription factor 2
|
3.71337
|
|
PPARG
|
peroxisome proliferator-activated receptor gamma
|
3.44803
|
|
HMOX1
|
heme oxygenase 1
|
3.18187
|
|
MNAT1
|
MNAT CDK-activating kinase assembly factor 1
|
3.1303
|
|
CNRIP1
|
cannabinoid receptor interacting protein 1
|
2.87893
|
|
SIRT3
|
sirtuin 3
|
2.85243
|
|
NOSIP
|
nitric oxide synthase interacting protein
|
2.65113
|
|
TMEM101
|
transmembrane protein 101
|
2.5051
|
|
OLFML2B
|
olfactomedin-like 2B
|
2.4878
|
|
CKB
|
creatine kinase, brain
|
2.32387
|
|
SREBF1
|
sterol regulatory element binding transcription factor 1
|
2.31427
|
|
HOXD10
|
homeobox D10
|
2.26237
|
|
TERF2
|
telomeric repeat binding factor 2
|
2.252
|
|
CS
|
citrate synthase
|
2.23943
|
|
MXD3
|
MAX dimerization protein 3
|
2.23523
|
|
FOXK2
|
forkhead box K2
|
2.15777
|
|
POLR2B
|
polymerase (RNA) II (DNA directed) polypeptide B, 140kDa
|
2.15437
|
|
HBB
|
hemoglobin, beta
|
2.11207
|
|
PROSER1
|
proline and serine rich 1
|
2.09127
|
|
DLX6
|
distal-less homeobox 6
|
2.07
|
|
TRPV4
|
transient receptor potential cation channel, subfamily V, member 4
|
2.0697
|
|
CDADC1
|
cytidine and dCMP deaminase domain containing 1
|
2.05537
|
|
MCUR1
|
mitochondrial calcium uniporter regulator 1
|
2.05313
|
|
IL36A
|
interleukin 36, alpha
|
2.04823
|
|
POU4F1
|
POU class 4 homeobox 1
|
2.02605
|
|
GRIP2
|
glutamate receptor interacting protein 2
|
2.01967
|
|
OBI1
|
ORC ubiquitin ligase 1
|
2.0175
|
|
MYL3
|
myosin, light chain 3, alkali; ventricular, skeletal, slow
|
2.00267
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
KIF14
|
kinesin family member 14
|
-6.43833
|
|
MSN
|
moesin
|
-4.56723
|
|
TUBB6
|
tubulin, beta 6 class V
|
-3.49303
|
|
MSMO1
|
methylsterol monooxygenase 1
|
-3.33333
|
|
HMGCS1
|
3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)
|
-3.3231
|
|
ENOPH1
|
enolase-phosphatase 1
|
-3.2458
|
|
TXNDC9
|
thioredoxin domain containing 9
|
-3.22048
|
|
HMG20B
|
high mobility group 20B
|
-3.20302
|
|
TRAPPC3
|
trafficking protein particle complex 3
|
-3.17707
|
|
GOLT1B
|
golgi transport 1B
|
-3.1317
|
|
TUBA4A
|
tubulin, alpha 4a
|
-2.97013
|
|
LSM5
|
LSM5 homolog, U6 small nuclear RNA associated (S. cerevisiae)
|
-2.58823
|
|
IGFBP7
|
insulin-like growth factor binding protein 7
|
-2.54615
|
|
SEC61G
|
Sec61 gamma subunit
|
-2.53527
|
|
ASPM
|
asp (abnormal spindle) homolog, microcephaly associated (Drosophila)
|
-2.50123
|
|
ORC6
|
origin recognition complex, subunit 6
|
-2.43707
|
|
PIH1D1
|
PIH1 domain containing 1
|
-2.4263
|
|
EXT1
|
exostosin glycosyltransferase 1
|
-2.40613
|
|
VAT1
|
vesicle amine transport 1
|
-2.3675
|
|
KIF1A
|
kinesin family member 1A
|
-2.2425
|
|
AZIN2
|
antizyme inhibitor 2
|
-2.1962
|
|
PPFIBP2
|
PTPRF interacting protein, binding protein 2 (liprin beta 2)
|
-2.17023
|
|
UBE2V2
|
ubiquitin-conjugating enzyme E2 variant 2
|
-2.13377
|
|
RBM34
|
RNA binding motif protein 34
|
-2.08872
|
|
SNX10
|
sorting nexin 10
|
-2.0696
|
|
ZNF432
|
zinc finger protein 432
|
-2.0497
|
|
SETD6
|
SET domain containing 6
|
-2.0475
|
|
G3BP1
|
GTPase activating protein (SH3 domain) binding protein 1
|
-2.04603
|
|
ARHGEF3
|
Rho guanine nucleotide exchange factor (GEF) 3
|
-2.04327
|
|
RBBP5
|
retinoblastoma binding protein 5
|
-2.03767
|
|
UQCR10
|
ubiquinol-cytochrome c reductase, complex III subunit X
|
-2.03693
|
|
STAC
|
SH3 and cysteine rich domain
|
-2.023
|
|
POP5
|
processing of precursor 5, ribonuclease P/MRP subunit (S. cerevisiae)
|
-2.0158
|
|
SUCO
|
SUN domain containing ossification factor
|
-2.002
|
