CRCGN017_MCF10A.TP53.M_24H:F09 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description scopolamine hydrobromide tri-hydrate 11.22 um perturbation at 24 h in MCF10A.TP53.M (Carcinogenome)
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Genes

18 genes differentially expressed following the CRCGN017_MCF10A.TP53.M_24H:F09 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
CCL2 chemokine (C-C motif) ligand 2 4.61049
BDH1 3-hydroxybutyrate dehydrogenase, type 1 2.66941
TIMM22 translocase of inner mitochondrial membrane 22 homolog (yeast) 2.38591
GADD45A growth arrest and DNA-damage-inducible, alpha 2.18334
CNPY3 canopy FGF signaling regulator 3 2.15474
BRMS1L breast cancer metastasis-suppressor 1-like 2.04023
RBKS ribokinase 2.0059

decreased expression

Symbol Name Standardized Value
LDHD lactate dehydrogenase D -4.25893
SESN1 sestrin 1 -4.18689
TSPAN4 tetraspanin 4 -4.14516
NPDC1 neural proliferation, differentiation and control, 1 -4.03757
TRAPPC3 trafficking protein particle complex 3 -3.96012
NSDHL NAD(P) dependent steroid dehydrogenase-like -3.64989
REEP5 receptor accessory protein 5 -2.29177
TSG101 tumor susceptibility 101 -2.08848
RNF34 ring finger protein 34, E3 ubiquitin protein ligase -2.07222
MRPS15 mitochondrial ribosomal protein S15 -2.07082
CRYZL1 crystallin, zeta (quinone reductase)-like 1 -2.03837