CRCGN017_MCF10A.TP53.M_24H:F14 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description l-ascorbic acid 33.66 um perturbation at 24 h in MCF10A.TP53.M (Carcinogenome)
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Genes

17 genes differentially expressed following the CRCGN017_MCF10A.TP53.M_24H:F14 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
ADGRE5 adhesion G protein-coupled receptor E5 5.87996
ST3GAL5 ST3 beta-galactoside alpha-2,3-sialyltransferase 5 4.0675
CNRIP1 cannabinoid receptor interacting protein 1 3.70812
PPARG peroxisome proliferator-activated receptor gamma 3.69097
SLC37A4 solute carrier family 37 (glucose-6-phosphate transporter), member 4 3.60538
DNAJB2 DnaJ (Hsp40) homolog, subfamily B, member 2 3.38785
KCTD5 potassium channel tetramerization domain containing 5 2.67006
AGR2 anterior gradient 2 2.60461
LGMN legumain 2.31179
DNAJB1 DnaJ (Hsp40) homolog, subfamily B, member 1 2.29156
PLEKHJ1 pleckstrin homology domain containing, family J member 1 2.0551

decreased expression

Symbol Name Standardized Value
KRT14 keratin 14, type I -4.98329
TES testin LIM domain protein -4.33538
PPP2R5E protein phosphatase 2, regulatory subunit B', epsilon isoform -2.55329
HTRA1 HtrA serine peptidase 1 -2.45908
EIF5 eukaryotic translation initiation factor 5 -2.31389
TENT4A terminal nucleotidyltransferase 4A -2.05511