CRCGN017_MCF10A.TP53.M_24H:F15 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description l-ascorbic acid 11.22 um perturbation at 24 h in MCF10A.TP53.M (Carcinogenome)
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Genes

13 genes differentially expressed following the CRCGN017_MCF10A.TP53.M_24H:F15 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
KCTD5 potassium channel tetramerization domain containing 5 5.13529
ST3GAL5 ST3 beta-galactoside alpha-2,3-sialyltransferase 5 4.39275
CCL2 chemokine (C-C motif) ligand 2 3.99108
AGR2 anterior gradient 2 2.51188
IGFBP3 insulin-like growth factor binding protein 3 2.4831
COQ8A coenzyme Q8A 2.3505
PDLIM1 PDZ and LIM domain 1 2.16929
SNAPC2 small nuclear RNA activating complex, polypeptide 2, 45kDa 2.09789

decreased expression

Symbol Name Standardized Value
GOLT1B golgi transport 1B -4.67005
FASTKD5 FAST kinase domains 5 -3.50551
GRN granulin -2.35195
STAT1 signal transducer and activator of transcription 1, 91kDa -2.21836
RECQL RecQ helicase-like -2.07123