CRCGN017_MCF10A.TP53.M_24H:F18 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description 1,2-dibromoethane 10.99 um perturbation at 24 h in MCF10A.TP53.M (Carcinogenome)
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Genes

16 genes differentially expressed following the CRCGN017_MCF10A.TP53.M_24H:F18 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
STAP2 signal transducing adaptor family member 2 3.81043
CCP110 centriolar coiled coil protein 110kDa 3.1461
CNRIP1 cannabinoid receptor interacting protein 1 3.1085
AGL amylo-alpha-1, 6-glucosidase, 4-alpha-glucanotransferase 2.78667
VGLL4 vestigial-like family member 4 2.24727
ADAM10 ADAM metallopeptidase domain 10 2.10362
PCDHB11 protocadherin beta 11 2.08631

decreased expression

Symbol Name Standardized Value
SLC7A5 solute carrier family 7 (amino acid transporter light chain, L system), member 5 -3.58413
BASP1 brain abundant, membrane attached signal protein 1 -3.39147
TRAPPC3 trafficking protein particle complex 3 -3.09422
TARBP1 TAR (HIV-1) RNA binding protein 1 -2.98377
BAG3 BCL2-associated athanogene 3 -2.88967
ADH5 alcohol dehydrogenase 5 (class III), chi polypeptide -2.758
PCNA proliferating cell nuclear antigen -2.69197
UBE3C ubiquitin protein ligase E3C -2.424
MRPS15 mitochondrial ribosomal protein S15 -2.14493