| Dataset | Carcinogenome Chemical Perturbation Carcinogenicity Signatures |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | o,o-diethyl o-(4-nitrophenyl) thiophosphate 101.97 um perturbation at 24 h in MCF10A.TP53.M (Carcinogenome) |
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95 genes differentially expressed following the CRCGN017_MCF10A.TP53.M_24H:F19 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| ABHD6 | abhydrolase domain containing 6 | 10.0 |
| CXCR4 | chemokine (C-X-C motif) receptor 4 | 9.77937 |
| NUDT9 | nudix (nucleoside diphosphate linked moiety X)-type motif 9 | 8.8055 |
| TIAM1 | T-cell lymphoma invasion and metastasis 1 | 6.42745 |
| GPATCH8 | G patch domain containing 8 | 5.7139 |
| GARRE1 | granule associated Rac and RHOG effector 1 | 4.5846 |
| GSTZ1 | glutathione S-transferase zeta 1 | 4.0536 |
| MCUR1 | mitochondrial calcium uniporter regulator 1 | 3.385 |
| FCHO1 | FCH domain only 1 | 3.313 |
| DNASE1L3 | deoxyribonuclease I-like 3 | 3.234 |
| DDX10 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 10 | 3.0105 |
| CCNA1 | cyclin A1 | 2.974 |
| SELL | selectin L | 2.8108 |
| ACSS3 | acyl-CoA synthetase short-chain family member 3 | 2.7213 |
| ATP1A4 | ATPase, Na+/K+ transporting, alpha 4 polypeptide | 2.6876 |
| KDSR | 3-ketodihydrosphingosine reductase | 2.6511 |
| COMP | cartilage oligomeric matrix protein | 2.642 |
| KDELR1 | KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 1 | 2.6141 |
| OLFML2B | olfactomedin-like 2B | 2.5077 |
| NKX2-2 | NK2 homeobox 2 | 2.4508 |
| ACOX2 | acyl-CoA oxidase 2, branched chain | 2.4419 |
| BANF1 | barrier to autointegration factor 1 | 2.43 |
| GNA15 | guanine nucleotide binding protein (G protein), alpha 15 (Gq class) | 2.3654 |
| SATB1 | SATB homeobox 1 | 2.3072 |
| CLCA2 | chloride channel accessory 2 | 2.29605 |
| DHPS | deoxyhypusine synthase | 2.27947 |
| COQ8A | coenzyme Q8A | 2.2539 |
| MDFI | MyoD family inhibitor | 2.2421 |
| NDUFS7 | NADH dehydrogenase (ubiquinone) Fe-S protein 7, 20kDa (NADH-coenzyme Q reductase) | 2.2385 |
| USO1 | USO1 vesicle transport factor | 2.21455 |
| CCL21 | chemokine (C-C motif) ligand 21 | 2.2024 |
| FLVCR2 | feline leukemia virus subgroup C cellular receptor family, member 2 | 2.1862 |
| PPID | peptidylprolyl isomerase D | 2.1573 |
| YWHAE | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon | 2.1265 |
| MRPS27 | mitochondrial ribosomal protein S27 | 2.1263 |
| MGA | MGA, MAX dimerization protein | 2.1221 |
| FXYD5 | FXYD domain containing ion transport regulator 5 | 2.1217 |
| FADS2 | fatty acid desaturase 2 | 2.0804 |
| USP5 | ubiquitin specific peptidase 5 (isopeptidase T) | 2.064 |
| DHRS2 | dehydrogenase/reductase (SDR family) member 2 | 2.0579 |
| ANXA7 | annexin A7 | 2.049 |
| PDLIM2 | PDZ and LIM domain 2 (mystique) | 2.0465 |
| AREG | amphiregulin | 2.03025 |
| ATP10D | ATPase, class V, type 10D | 2.0295 |
| TTC3 | tetratricopeptide repeat domain 3 | 2.02903 |
| AP1S1 | adaptor-related protein complex 1, sigma 1 subunit | 2.02653 |
| FOXJ2 | forkhead box J2 | 2.0262 |
| TNFAIP3 | tumor necrosis factor, alpha-induced protein 3 | 2.01335 |
| JUN | jun proto-oncogene | 2.00797 |
| Symbol | Name | Standardized Value |
|---|---|---|
| PCCB | propionyl CoA carboxylase, beta polypeptide | -5.4834 |
| ALDH7A1 | aldehyde dehydrogenase 7 family, member A1 | -4.64023 |
| DNAJB6 | DnaJ (Hsp40) homolog, subfamily B, member 6 | -4.4071 |
| NGRN | neugrin, neurite outgrowth associated | -4.0234 |
| XKR8 | XK, Kell blood group complex subunit-related family, member 8 | -2.7425 |
| ZNF239 | zinc finger protein 239 | -2.7286 |
| DEPTOR | DEP domain containing MTOR-interacting protein | -2.5489 |
| ZNF33B | zinc finger protein 33B | -2.5302 |
| CABYR | calcium binding tyrosine-(Y)-phosphorylation regulated | -2.5219 |
| GPC5 | glypican 5 | -2.4657 |
| AMIGO2 | adhesion molecule with Ig-like domain 2 | -2.4441 |
| SNX4 | sorting nexin 4 | -2.4266 |
| TRIM24 | tripartite motif containing 24 | -2.3861 |
| RGS2 | regulator of G-protein signaling 2 | -2.3424 |
| GPR143 | G protein-coupled receptor 143 | -2.3124 |
| SLC12A2 | solute carrier family 12 (sodium/potassium/chloride transporter), member 2 | -2.2971 |
| ZNF211 | zinc finger protein 211 | -2.2867 |
| REXO5 | RNA exonuclease 5 | -2.2596 |
| NECAB2 | N-terminal EF-hand calcium binding protein 2 | -2.2566 |
| SERPINA5 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 5 | -2.2401 |
| PPP2R3C | protein phosphatase 2, regulatory subunit B'', gamma | -2.2237 |
| ZNF84 | zinc finger protein 84 | -2.2122 |
| CHIA | chitinase, acidic | -2.2017 |
| DRAM1 | DNA-damage regulated autophagy modulator 1 | -2.2013 |
| ZNF268 | zinc finger protein 268 | -2.199 |
| MATN2 | matrilin 2 | -2.1983 |
| ZKSCAN3 | zinc finger with KRAB and SCAN domains 3 | -2.1833 |
| NSG2 | neuronal vesicle trafficking associated 2 | -2.1548 |
| CEACAM1 | carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein) | -2.11372 |
| NOCT | nocturnin | -2.1015 |
| XK | X-linked Kx blood group | -2.0978 |
| PROM1 | prominin 1 | -2.0962 |
| NR2E1 | nuclear receptor subfamily 2, group E, member 1 | -2.0918 |
| ATP11B | ATPase, class VI, type 11B | -2.0859 |
| GABRB1 | gamma-aminobutyric acid (GABA) A receptor, beta 1 | -2.0838 |
| ACADS | acyl-CoA dehydrogenase, C-2 to C-3 short chain | -2.0787 |
| CRBN | cereblon | -2.0677 |
| RRAS2 | related RAS viral (r-ras) oncogene homolog 2 | -2.04273 |
| INPP5D | inositol polyphosphate-5-phosphatase, 145kDa | -2.0381 |
| KLHDC4 | kelch domain containing 4 | -2.0367 |
| RPGRIP1 | retinitis pigmentosa GTPase regulator interacting protein 1 | -2.0358 |
| ADAMTS3 | ADAM metallopeptidase with thrombospondin type 1 motif, 3 | -2.0357 |
| IRAG2 | inositol 1,4,5-triphosphate receptor associated 2 | -2.03275 |
| IFRD1 | interferon-related developmental regulator 1 | -2.03125 |
| SLC39A14 | solute carrier family 39 (zinc transporter), member 14 | -2.0043 |
| PLA2G2D | phospholipase A2, group IID | -2.0006 |
