CRCGN017_MCF10A.TP53.M_24H:G02 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description tris(1-chloro-2-propanyl) phosphate 33.66 um perturbation at 24 h in MCF10A.TP53.M (Carcinogenome)
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Genes

25 genes differentially expressed following the CRCGN017_MCF10A.TP53.M_24H:G02 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
VAV3 vav 3 guanine nucleotide exchange factor 5.20665
KIF5C kinesin family member 5C 4.35585
DYRK3 dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3 4.18975
ST6GALNAC2 ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2 3.6363
TSEN2 TSEN2 tRNA splicing endonuclease subunit 3.51145
TSPAN6 tetraspanin 6 2.5848
TBXA2R thromboxane A2 receptor 2.48559
RPS6KA1 ribosomal protein S6 kinase, 90kDa, polypeptide 1 2.37905
LY6G6F-LY6G6D LY6G6F-LY6G6D readthrough 2.22385
WASF1 WAS protein family, member 1 2.2117
PACSIN3 protein kinase C and casein kinase substrate in neurons 3 2.13085
SYNGAP1 synaptic Ras GTPase activating protein 1 2.1283
CHAC1 ChaC glutathione-specific gamma-glutamylcyclotransferase 1 2.1168
FN3KRP fructosamine 3 kinase related protein 2.08105
PLSCR3 phospholipid scramblase 3 2.01405

decreased expression

Symbol Name Standardized Value
NRIP1 nuclear receptor interacting protein 1 -4.26065
SCYL3 SCY1-like 3 (S. cerevisiae) -4.04967
TOR1A torsin family 1, member A (torsin A) -3.6651
CRK v-crk avian sarcoma virus CT10 oncogene homolog -3.60955
TOMM70 translocase of outer mitochondrial membrane 70 -2.388
CHORDC1 cysteine and histidine-rich domain (CHORD) containing 1 -2.31408
CIAPIN1 cytokine induced apoptosis inhibitor 1 -2.31115
BPHL biphenyl hydrolase-like (serine hydrolase) -2.18325
RGS2 regulator of G-protein signaling 2 -2.1829
NOD2 nucleotide-binding oligomerization domain containing 2 -2.11605