CRCGN017_MCF10A.TP53.M_24H:G03 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description tris(1-chloro-2-propanyl) phosphate 11.22 um perturbation at 24 h in MCF10A.TP53.M (Carcinogenome)
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Genes

37 genes differentially expressed following the CRCGN017_MCF10A.TP53.M_24H:G03 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
ADGRE5 adhesion G protein-coupled receptor E5 5.22326
USP7 ubiquitin specific peptidase 7 (herpes virus-associated) 3.76502
LGMN legumain 3.19706
HBA1 hemoglobin, alpha 1 3.08831
RELB v-rel avian reticuloendotheliosis viral oncogene homolog B 2.86934
ABCC5 ATP-binding cassette, sub-family C (CFTR/MRP), member 5 2.57844
KDM5D lysine (K)-specific demethylase 5D 2.35051
TRAPPC8 trafficking protein particle complex 8 2.34206
EIF1AY eukaryotic translation initiation factor 1A, Y-linked 2.33484
DDX3Y DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked 2.28969
TIMM22 translocase of inner mitochondrial membrane 22 homolog (yeast) 2.2483
ST3GAL5 ST3 beta-galactoside alpha-2,3-sialyltransferase 5 2.1903
CHMP6 charged multivesicular body protein 6 2.18094
METTL22 methyltransferase like 22 2.11453
OXSR1 oxidative stress responsive 1 2.10573
ERI2 ERI1 exoribonuclease family member 2 2.09864
TCFL5 transcription factor-like 5 (basic helix-loop-helix) 2.09821
NFATC3 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3 2.08308
PKIG protein kinase (cAMP-dependent, catalytic) inhibitor gamma 2.07588
NAPSA napsin A aspartic peptidase 2.06508
ASPSCR1 alveolar soft part sarcoma chromosome region, candidate 1 2.05964
YBX3 Y box binding protein 3 2.02753
ACAA1 acetyl-CoA acyltransferase 1 2.00351

decreased expression

Symbol Name Standardized Value
HACD3 3-hydroxyacyl-CoA dehydratase 3 -6.31528
VDAC1 voltage-dependent anion channel 1 -4.81411
MAP4K4 mitogen-activated protein kinase kinase kinase kinase 4 -3.40232
RAI14 retinoic acid induced 14 -3.20917
ALDH7A1 aldehyde dehydrogenase 7 family, member A1 -2.93583
PCNA proliferating cell nuclear antigen -2.82907
TMEM230 transmembrane protein 230 -2.68246
FGD6 FYVE, RhoGEF and PH domain containing 6 -2.51883
TXLNG taxilin gamma -2.20804
THAP11 THAP domain containing 11 -2.12243
UBA1 ubiquitin-like modifier activating enzyme 1 -2.06831
IGFBP7 insulin-like growth factor binding protein 7 -2.04058
SMC1A structural maintenance of chromosomes 1A -2.0362
PRRG1 proline rich Gla (G-carboxyglutamic acid) 1 -2.00249