CRCGN017_MCF10A.TP53.M_24H:G05 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description 1,1-dichloroethane 32.48 um perturbation at 24 h in MCF10A.TP53.M (Carcinogenome)
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Genes

29 genes differentially expressed following the CRCGN017_MCF10A.TP53.M_24H:G05 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
ST3GAL5 ST3 beta-galactoside alpha-2,3-sialyltransferase 5 4.23116
KIF5C kinesin family member 5C 3.84845
DNAJB2 DnaJ (Hsp40) homolog, subfamily B, member 2 3.63352
WFS1 Wolfram syndrome 1 (wolframin) 3.60023
AXIN1 axin 1 2.81276
AGR2 anterior gradient 2 2.5807
ACAA1 acetyl-CoA acyltransferase 1 2.29165
IGFBP3 insulin-like growth factor binding protein 3 2.04438

decreased expression

Symbol Name Standardized Value
RNF167 ring finger protein 167 -4.76043
PSMB8 proteasome (prosome, macropain) subunit, beta type, 8 -4.2704
HSPA8 heat shock 70kDa protein 8 -4.17972
NUP93 nucleoporin 93kDa -4.13982
HMG20B high mobility group 20B -3.93574
C2CD5 C2 calcium-dependent domain containing 5 -3.53108
SCYL3 SCY1-like 3 (S. cerevisiae) -3.37186
PCNA proliferating cell nuclear antigen -3.22755
BASP1 brain abundant, membrane attached signal protein 1 -2.87926
IDH3B isocitrate dehydrogenase 3 (NAD+) beta -2.46057
KIF20A kinesin family member 20A -2.37788
RNF44 ring finger protein 44 -2.29478
ZNF646 zinc finger protein 646 -2.29176
MATK megakaryocyte-associated tyrosine kinase -2.24078
NGRN neugrin, neurite outgrowth associated -2.23738
RCE1 Ras converting CAAX endopeptidase 1 -2.23479
FKBP6 FK506 binding protein 6, 36kDa -2.17932
CHD9NB CHD9 neighbor -2.17451
ASAP2 ArfGAP with SH3 domain, ankyrin repeat and PH domain 2 -2.11772
ETV4 ets variant 4 -2.06751
UNC93B1 unc-93 homolog B1 (C. elegans) -2.04826