| Dataset | Carcinogenome Chemical Perturbation Carcinogenicity Signatures |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | 1-phenyl-2-thiourea 102.48 um perturbation at 24 h in MCF10A.TP53.M (Carcinogenome) |
| Similar Terms | |
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55 genes differentially expressed following the CRCGN017_MCF10A.TP53.M_24H:G07 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| CCDC92 | coiled-coil domain containing 92 | 4.6883 |
| SUV39H1 | suppressor of variegation 3-9 homolog 1 (Drosophila) | 4.19141 |
| KDM5D | lysine (K)-specific demethylase 5D | 4.16729 |
| CNRIP1 | cannabinoid receptor interacting protein 1 | 4.01354 |
| FGFR4 | fibroblast growth factor receptor 4 | 3.85526 |
| EIF1AY | eukaryotic translation initiation factor 1A, Y-linked | 3.79397 |
| DDX3Y | DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked | 3.20168 |
| HBA1 | hemoglobin, alpha 1 | 2.98085 |
| USP9Y | ubiquitin specific peptidase 9, Y-linked | 2.59953 |
| FMO3 | flavin containing monooxygenase 3 | 2.35242 |
| UTY | ubiquitously transcribed tetratricopeptide repeat containing, Y-linked | 2.34595 |
| SATB1 | SATB homeobox 1 | 2.3441 |
| WDR18 | WD repeat domain 18 | 2.31929 |
| BAHD1 | bromo adjacent homology domain containing 1 | 2.31795 |
| BRMS1L | breast cancer metastasis-suppressor 1-like | 2.30932 |
| HPR | haptoglobin-related protein | 2.29385 |
| SLC25A38 | solute carrier family 25, member 38 | 2.25282 |
| TLE5 | TLE family member 5, transcriptional modulator | 2.24666 |
| NUDT18 | nudix (nucleoside diphosphate linked moiety X)-type motif 18 | 2.23279 |
| KAT6B | K(lysine) acetyltransferase 6B | 2.21116 |
| SPDEF | SAM pointed domain containing ETS transcription factor | 2.1344 |
| MAP1S | microtubule-associated protein 1S | 2.12972 |
| SF3A2 | splicing factor 3a, subunit 2, 66kDa | 2.11533 |
| PDLIM1 | PDZ and LIM domain 1 | 2.08226 |
| HBB | hemoglobin, beta | 2.06732 |
| SNCA | synuclein, alpha (non A4 component of amyloid precursor) | 2.02982 |
| Symbol | Name | Standardized Value |
|---|---|---|
| LDHD | lactate dehydrogenase D | -4.82042 |
| MAPK13 | mitogen-activated protein kinase 13 | -4.77635 |
| ITGAE | integrin, alpha E (antigen CD103, human mucosal lymphocyte antigen 1; alpha polypeptide) | -4.66952 |
| CCDC86 | coiled-coil domain containing 86 | -4.42035 |
| TRAPPC3 | trafficking protein particle complex 3 | -4.40863 |
| BASP1 | brain abundant, membrane attached signal protein 1 | -3.24382 |
| TUBA4A | tubulin, alpha 4a | -3.02772 |
| LOC124905557 | eukaryotic translation initiation factor 1A, X-chromosomal | -2.98237 |
| NAMPT | nicotinamide phosphoribosyltransferase | -2.95069 |
| SMC1A | structural maintenance of chromosomes 1A | -2.81866 |
| AGO1 | argonaute RISC catalytic component 1 | -2.78833 |
| PUDP | pseudouridine 5'-phosphatase | -2.73711 |
| KDM5C | lysine (K)-specific demethylase 5C | -2.65811 |
| MRPS15 | mitochondrial ribosomal protein S15 | -2.61486 |
| ACADM | acyl-CoA dehydrogenase, C-4 to C-12 straight chain | -2.57863 |
| DUS4L | dihydrouridine synthase 4-like (S. cerevisiae) | -2.46082 |
| PSMC2 | proteasome (prosome, macropain) 26S subunit, ATPase, 2 | -2.43064 |
| IFRD1 | interferon-related developmental regulator 1 | -2.42068 |
| NCBP3 | nuclear cap binding subunit 3 | -2.32534 |
| NGRN | neugrin, neurite outgrowth associated | -2.304 |
| COG5 | component of oligomeric golgi complex 5 | -2.27809 |
| RAB5IF | RAB5 interacting factor | -2.27566 |
| HMGCR | 3-hydroxy-3-methylglutaryl-CoA reductase | -2.23966 |
| AP1B1 | adaptor-related protein complex 1, beta 1 subunit | -2.15629 |
| BCAP29 | B-cell receptor-associated protein 29 | -2.12079 |
| TCHH | trichohyalin | -2.10436 |
| PNPLA4 | patatin-like phospholipase domain containing 4 | -2.03763 |
| CBLL1 | Cbl proto-oncogene-like 1, E3 ubiquitin protein ligase | -2.02637 |
| RASA4B | RAS p21 protein activator 4B | -2.01068 |
