CRCGN017_MCF10A.TP53.M_24H:G20 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description methylene chloride 32.93 um perturbation at 24 h in MCF10A.TP53.M (Carcinogenome)
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Genes

19 genes differentially expressed following the CRCGN017_MCF10A.TP53.M_24H:G20 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
HMOX1 heme oxygenase 1 6.27297
CHMP6 charged multivesicular body protein 6 4.57709
ABCC5 ATP-binding cassette, sub-family C (CFTR/MRP), member 5 4.50913
WFS1 Wolfram syndrome 1 (wolframin) 4.45049
PPP1R13B protein phosphatase 1, regulatory subunit 13B 2.91401
TCTN1 tectonic family member 1 2.3237
HSD17B11 hydroxysteroid (17-beta) dehydrogenase 11 2.32245
VPS28 vacuolar protein sorting 28 homolog (S. cerevisiae) 2.18408

decreased expression

Symbol Name Standardized Value
DNAJA3 DnaJ (Hsp40) homolog, subfamily A, member 3 -4.65113
PCNA proliferating cell nuclear antigen -4.3951
VDAC1 voltage-dependent anion channel 1 -4.28654
SCYL3 SCY1-like 3 (S. cerevisiae) -3.72818
PIH1D1 PIH1 domain containing 1 -3.09333
CCNL2 cyclin L2 -2.6636
PANK2 pantothenate kinase 2 -2.41914
MAVS mitochondrial antiviral signaling protein -2.41111
ANKRA2 ankyrin repeat, family A (RFXANK-like), 2 -2.16883
CDKN2A cyclin-dependent kinase inhibitor 2A -2.11569
PCCB propionyl CoA carboxylase, beta polypeptide -2.06932