| Dataset | Carcinogenome Chemical Perturbation Carcinogenicity Signatures |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | n-nitrosopiperidine 100.46 um perturbation at 24 h in MCF10A.TP53.M (Carcinogenome) |
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62 genes differentially expressed following the CRCGN017_MCF10A.TP53.M_24H:H01 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| FKBP14 | FK506 binding protein 14, 22 kDa | 4.7883 |
| ADO | 2-aminoethanethiol (cysteamine) dioxygenase | 4.55293 |
| KIF5C | kinesin family member 5C | 4.27943 |
| TXNL4B | thioredoxin-like 4B | 4.2303 |
| ACLY | ATP citrate lyase | 4.20957 |
| LOC122526780 | uncharacterized LOC122526780 | 4.031 |
| MICALL1 | MICAL-like 1 | 3.62617 |
| PPP1R13B | protein phosphatase 1, regulatory subunit 13B | 3.57475 |
| GPER1 | G protein-coupled estrogen receptor 1 | 3.5601 |
| FGFR4 | fibroblast growth factor receptor 4 | 3.1106 |
| TBC1D31 | TBC1 domain family, member 31 | 2.97245 |
| NUCB2 | nucleobindin 2 | 2.8836 |
| ACAA1 | acetyl-CoA acyltransferase 1 | 2.87915 |
| TBX2 | T-box 2 | 2.84075 |
| TBPL1 | TBP-like 1 | 2.50485 |
| INTS6 | integrator complex subunit 6 | 2.47447 |
| DNAJB14 | DnaJ (Hsp40) homolog, subfamily B, member 14 | 2.45175 |
| DCUN1D4 | DCN1, defective in cullin neddylation 1, domain containing 4 | 2.38828 |
| GPHRA | golgi pH regulator A | 2.38777 |
| TMEM51 | transmembrane protein 51 | 2.38045 |
| DMXL1 | Dmx-like 1 | 2.3761 |
| SMTN | smoothelin | 2.35635 |
| SNCA | synuclein, alpha (non A4 component of amyloid precursor) | 2.34983 |
| RECQL | RecQ helicase-like | 2.3451 |
| HBA1 | hemoglobin, alpha 1 | 2.32375 |
| KLK11 | kallikrein-related peptidase 11 | 2.3112 |
| CIC | capicua transcriptional repressor | 2.16155 |
| MRM2 | mitochondrial rRNA methyltransferase 2 | 2.13835 |
| PRR16 | proline rich 16 | 2.0958 |
| FLNA | filamin A, alpha | 2.05558 |
| TRAPPC11 | trafficking protein particle complex 11 | 2.0218 |
| FIP1L1 | factor interacting with PAPOLA and CPSF1 | 2.0089 |
| Symbol | Name | Standardized Value |
|---|---|---|
| RPIA | ribose 5-phosphate isomerase A | -4.1737 |
| CIAPIN1 | cytokine induced apoptosis inhibitor 1 | -3.38205 |
| CAB39 | calcium binding protein 39 | -3.1678 |
| CD81 | CD81 molecule | -3.1654 |
| CANT1 | calcium activated nucleotidase 1 | -2.9336 |
| KDM3A | lysine (K)-specific demethylase 3A | -2.79035 |
| TMEM9B | TMEM9 domain family, member B | -2.3866 |
| CHORDC1 | cysteine and histidine-rich domain (CHORD) containing 1 | -2.37765 |
| GPA33 | glycoprotein A33 (transmembrane) | -2.349 |
| OTC | ornithine carbamoyltransferase | -2.2962 |
| CDKL2 | cyclin-dependent kinase-like 2 (CDC2-related kinase) | -2.2728 |
| TPGS2 | tubulin polyglutamylase complex subunit 2 | -2.20807 |
| NFKBIA | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha | -2.1814 |
| TFCP2L1 | transcription factor CP2-like 1 | -2.16705 |
| FAM222B | family with sequence similarity 222, member B | -2.1648 |
| ITPA | inosine triphosphatase (nucleoside triphosphate pyrophosphatase) | -2.1629 |
| CXCL14 | chemokine (C-X-C motif) ligand 14 | -2.1566 |
| MARCHF3 | membrane associated ring-CH-type finger 3 | -2.141 |
| OR7A5 | olfactory receptor, family 7, subfamily A, member 5 | -2.1379 |
| SIGLEC5 | sialic acid binding Ig-like lectin 5 | -2.135 |
| PSMB7 | proteasome (prosome, macropain) subunit, beta type, 7 | -2.1234 |
| WNT2 | wingless-type MMTV integration site family member 2 | -2.09885 |
| GREB1L | growth regulation by estrogen in breast cancer-like | -2.0802 |
| CCNK | cyclin K | -2.06175 |
| TTPA | tocopherol (alpha) transfer protein | -2.0474 |
| ACSL6 | acyl-CoA synthetase long-chain family member 6 | -2.04357 |
| CDX1 | caudal type homeobox 1 | -2.028 |
| PEAK1 | pseudopodium-enriched atypical kinase 1 | -2.00545 |
| TCEAL4 | transcription elongation factor A (SII)-like 4 | -2.0052 |
| MAFG | v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog G | -2.00485 |