CRCGN017_MCF10A.TP53.M_24H:H05 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description hexylresorcinol 33.82 um perturbation at 24 h in MCF10A.TP53.M (Carcinogenome)
Similar Terms
Downloads & Tools

Genes

73 genes differentially expressed following the CRCGN017_MCF10A.TP53.M_24H:H05 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
SQOR sulfide quinone oxidoreductase 3.9209
PPARG peroxisome proliferator-activated receptor gamma 3.62106
NUCB2 nucleobindin 2 3.389
ZNF586 zinc finger protein 586 3.16362
NR3C1 nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) 3.13726
OLFML2B olfactomedin-like 2B 2.78867
PYCR1 pyrroline-5-carboxylate reductase 1 2.62453
KDM5A lysine (K)-specific demethylase 5A 2.60256
CXCL2 chemokine (C-X-C motif) ligand 2 2.5926
TSKU tsukushi, small leucine rich proteoglycan 2.51088
TNIP1 TNFAIP3 interacting protein 1 2.45498
CSGALNACT1 chondroitin sulfate N-acetylgalactosaminyltransferase 1 2.40973
IER3 immediate early response 3 2.31338
REXO4 REX4, RNA exonuclease 4 homolog (S. cerevisiae) 2.25764
CTDSP1 CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase 1 2.24632
ZNF587B zinc finger protein 587B 2.22782
CXCL3 chemokine (C-X-C motif) ligand 3 2.21944
LIF leukemia inhibitory factor 2.18613
ZNF134 zinc finger protein 134 2.15462
TSC22D4 TSC22 domain family, member 4 2.1086
TAOK3 TAO kinase 3 2.0903
CXCL1 chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha) 2.0864
IL1B interleukin 1, beta 2.05505
PROCR protein C receptor, endothelial 2.0538
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor) 2.02965
DDX10 DEAD (Asp-Glu-Ala-Asp) box polypeptide 10 2.02564
RELB v-rel avian reticuloendotheliosis viral oncogene homolog B 2.02268
TIPIN TIMELESS interacting protein 2.00784

decreased expression

Symbol Name Standardized Value
CYCS cytochrome c, somatic -3.8085
COG7 component of oligomeric golgi complex 7 -3.77521
MRPL15 mitochondrial ribosomal protein L15 -3.55317
ITGAE integrin, alpha E (antigen CD103, human mucosal lymphocyte antigen 1; alpha polypeptide) -3.36543
GOLT1B golgi transport 1B -3.33661
LYPLA1 lysophospholipase I -3.0208
HMGCR 3-hydroxy-3-methylglutaryl-CoA reductase -2.90866
ACYP2 acylphosphatase 2, muscle type -2.89214
TCEA2 transcription elongation factor A (SII), 2 -2.58659
XPNPEP1 X-prolyl aminopeptidase (aminopeptidase P) 1, soluble -2.58116
GGA2 golgi-associated, gamma adaptin ear containing, ARF binding protein 2 -2.49164
SCGB1D1 secretoglobin, family 1D, member 1 -2.46628
MSMO1 methylsterol monooxygenase 1 -2.43706
EGFL6 EGF-like-domain, multiple 6 -2.33649
COX7B cytochrome c oxidase subunit VIIb -2.32412
DNAJC15 DnaJ (Hsp40) homolog, subfamily C, member 15 -2.32198
ADRB2 adrenoceptor beta 2, surface -2.31593
DBH dopamine beta-hydroxylase (dopamine beta-monooxygenase) -2.29615
CSAD cysteine sulfinic acid decarboxylase -2.29045
NDST4 N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 4 -2.27875
ANKRD6 ankyrin repeat domain 6 -2.27635
WBP11 WW domain binding protein 11 -2.25452
NDUFB5 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 5, 16kDa -2.24946
STMN2 stathmin 2 -2.2425
MTERF3 mitochondrial transcription termination factor 3 -2.2352
ELAVL4 ELAV like neuron-specific RNA binding protein 4 -2.21968
DNAJB1 DnaJ (Hsp40) homolog, subfamily B, member 1 -2.20175
CRKL v-crk avian sarcoma virus CT10 oncogene homolog-like -2.17327
DHCR24 24-dehydrocholesterol reductase -2.17277
CCDC6 coiled-coil domain containing 6 -2.15979
UTRN utrophin -2.15146
CMAS cytidine monophosphate N-acetylneuraminic acid synthetase -2.14341
CRMP1 collapsin response mediator protein 1 -2.14056
PCDH8 protocadherin 8 -2.13769
SUSD4 sushi domain containing 4 -2.10704
MPC1 mitochondrial pyruvate carrier 1 -2.10095
ZNF529 zinc finger protein 529 -2.08571
LSM1 LSM1, U6 small nuclear RNA associated -2.08264
CDKL3 cyclin-dependent kinase-like 3 -2.0787
EZR ezrin -2.07538
ATP5F1B ATP synthase F1 subunit beta -2.04212
NOTCH4 notch 4 -2.04063
TMEM242 transmembrane protein 242 -2.03397
SRD5A3 steroid 5 alpha-reductase 3 -2.02396
CIAPIN1 cytokine induced apoptosis inhibitor 1 -2.00364