CRCGN017_MCF10A.TP53.M_24H:H09 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description p-rosaniline.hcl 11.22 um perturbation at 24 h in MCF10A.TP53.M (Carcinogenome)
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Genes

1428 genes differentially expressed following the CRCGN017_MCF10A.TP53.M_24H:H09 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
HMOX1 heme oxygenase 1 9.78847
CXCL2 chemokine (C-X-C motif) ligand 2 9.11308
MTHFD2 methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase 8.91503
PCK2 phosphoenolpyruvate carboxykinase 2 (mitochondrial) 8.84735
DDX10 DEAD (Asp-Glu-Ala-Asp) box polypeptide 10 8.37035
GFPT1 glutamine--fructose-6-phosphate transaminase 1 8.13119
ATF4 activating transcription factor 4 8.09283
AARS1 alanyl-tRNA synthetase 1 8.05238
GLRX glutaredoxin (thioltransferase) 7.83098
TXNRD1 thioredoxin reductase 1 7.69005
HBA1 hemoglobin, alpha 1 7.41977
LOC128125814 uncharacterized LOC128125814 7.25344
POLD4 polymerase (DNA-directed), delta 4, accessory subunit 7.02183
ARHGEF2 Rho/Rac guanine nucleotide exchange factor (GEF) 2 6.86119
SLC1A4 solute carrier family 1 (glutamate/neutral amino acid transporter), member 4 6.8401
CHAC1 ChaC glutathione-specific gamma-glutamylcyclotransferase 1 6.6639
TRIB3 tribbles pseudokinase 3 6.53263
GARS1 glycyl-tRNA synthetase 1 6.53214
CCNA1 cyclin A1 6.43418
DNAJB2 DnaJ (Hsp40) homolog, subfamily B, member 2 6.40506
CARS1 cysteinyl-tRNA synthetase 1 6.40114
SLC7A11 solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 6.33006
WIF1 WNT inhibitory factor 1 6.29969
VSIG2 V-set and immunoglobulin domain containing 2 6.25929
IL1B interleukin 1, beta 6.09021
SLC3A2 solute carrier family 3 (amino acid transporter heavy chain), member 2 6.02451
AGR2 anterior gradient 2 5.94049
SARS1 seryl-tRNA synthetase 1 5.89165
CXCL3 chemokine (C-X-C motif) ligand 3 5.80178
SQSTM1 sequestosome 1 5.67214
TES testin LIM domain protein 5.58772
ASNS asparagine synthetase (glutamine-hydrolyzing) 5.54903
PSAT1 phosphoserine aminotransferase 1 5.53214
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 5.44603
PYCR1 pyrroline-5-carboxylate reductase 1 5.43601
XPOT exportin, tRNA 5.34733
TRIB1 tribbles pseudokinase 1 5.32266
DDIT4 DNA-damage-inducible transcript 4 5.28334
IFRD1 interferon-related developmental regulator 1 5.27192
FYN FYN proto-oncogene, Src family tyrosine kinase 5.24776
CHIC2 cysteine-rich hydrophobic domain 2 5.23686
YARS1 tyrosyl-tRNA synthetase 1 5.23182
NIT1 nitrilase 1 5.1832
PHGDH phosphoglycerate dehydrogenase 5.10891
ALAS1 5'-aminolevulinate synthase 1 5.06769
EGR1 early growth response 1 5.03655
EIF4EBP1 eukaryotic translation initiation factor 4E binding protein 1 4.97213
CTSL cathepsin L 4.94435
SHMT2 serine hydroxymethyltransferase 2 (mitochondrial) 4.92637
IER3 immediate early response 3 4.85517
GRB10 growth factor receptor-bound protein 10 4.79162
GSTZ1 glutathione S-transferase zeta 1 4.71893
H1-0 H1.0 linker histone 4.69964
NUCB2 nucleobindin 2 4.66466
HMGCL 3-hydroxymethyl-3-methylglutaryl-CoA lyase 4.52126
CEBPG CCAAT/enhancer binding protein (C/EBP), gamma 4.50893
ODR4 odr-4 GPCR localization factor homolog 4.4498
STX1A syntaxin 1A (brain) 4.41252
ATF3 activating transcription factor 3 4.40302
G0S2 G0/G1 switch 2 4.34798
HERPUD1 homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 4.30715
HYOU1 hypoxia up-regulated 1 4.2805
LIF leukemia inhibitory factor 4.26336
HBEGF heparin-binding EGF-like growth factor 4.23095
WFS1 Wolfram syndrome 1 (wolframin) 4.11773
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) 4.097
SLC35A1 solute carrier family 35 (CMP-sialic acid transporter), member A1 4.072
SYNGAP1 synaptic Ras GTPase activating protein 1 4.04355
GOLT1A golgi transport 1A 4.04061
NLRP4 NLR family, pyrin domain containing 4 4.03038
DNAJB9 DnaJ (Hsp40) homolog, subfamily B, member 9 4.02343
RAB3GAP1 RAB3 GTPase activating protein subunit 1 (catalytic) 4.02
MARS1 methionyl-tRNA synthetase 1 4.00985
FHL2 four and a half LIM domains 2 3.97846
ECH1 enoyl CoA hydratase 1, peroxisomal 3.96497
CDPF1 cysteine-rich, DPF motif domain containing 1 3.96281
INHBE inhibin, beta E 3.9571
EDEM1 ER degradation enhancer, mannosidase alpha-like 1 3.95677
SIL1 SIL1 nucleotide exchange factor 3.91032
GMPPA GDP-mannose pyrophosphorylase A 3.90911
PFDN2 prefoldin subunit 2 3.90748
EGR3 early growth response 3 3.90531
CAMTA2 calmodulin binding transcription activator 2 3.88049
STAMBP STAM binding protein 3.85735
STC2 stanniocalcin 2 3.85579
UPP1 uridine phosphorylase 1 3.85113
ANKRD11 ankyrin repeat domain 11 3.83258
KLHDC2 kelch domain containing 2 3.80843
STX5 syntaxin 5 3.80682
GTPBP2 GTP binding protein 2 3.80461
WARS1 tryptophanyl-tRNA synthetase 1 3.80359
UGDH UDP-glucose 6-dehydrogenase 3.77607
LYPLA1-TCEA1 LYPLA1-TCEA1 readthrough 3.75556
WIPI1 WD repeat domain, phosphoinositide interacting 1 3.7489
FOS FBJ murine osteosarcoma viral oncogene homolog 3.74643
AZIN2 antizyme inhibitor 2 3.74248
LARP6 La ribonucleoprotein domain family, member 6 3.73367
HAX1 HCLS1 associated protein X-1 3.73019
HBB hemoglobin, beta 3.72222
GOLGA3 golgin A3 3.71403
IBTK inhibitor of Bruton agammaglobulinemia tyrosine kinase 3.70907
FICD FIC domain containing 3.69234
NARS1 asparaginyl-tRNA synthetase 1 3.66756
PRAF2 PRA1 domain family, member 2 3.66601
ATP2B1 ATPase, Ca++ transporting, plasma membrane 1 3.64708
ZCCHC8 zinc finger, CCHC domain containing 8 3.62627
NUPR1 nuclear protein, transcriptional regulator, 1 3.57338
FOSL1 FOS-like antigen 1 3.55579
RBKS ribokinase 3.55174
TGIF1 TGFB-induced factor homeobox 1 3.54986
P4HA2 prolyl 4-hydroxylase, alpha polypeptide II 3.52821
EPRS1 glutamyl-prolyl-tRNA synthetase 1 3.51337
LOC102724560 cystathionine beta-synthase 3.49893
TRIP4 thyroid hormone receptor interactor 4 3.47151
TERF2IP telomeric repeat binding factor 2, interacting protein 3.46198
RELB v-rel avian reticuloendotheliosis viral oncogene homolog B 3.45924
MGLL monoglyceride lipase 3.45274
MOSPD2 motile sperm domain containing 2 3.44349
ETNPPL ethanolamine-phosphate phospho-lyase 3.44262
FNDC4 fibronectin type III domain containing 4 3.43793
MAP2K5 mitogen-activated protein kinase kinase 5 3.42137
ATF6 activating transcription factor 6 3.41473
CCDC92 coiled-coil domain containing 92 3.38477
KDM6B lysine (K)-specific demethylase 6B 3.37318
CHMP4B charged multivesicular body protein 4B 3.34581
ZFAND1 zinc finger, AN1-type domain 1 3.34234
IL1A interleukin 1, alpha 3.32883
PYGB phosphorylase, glycogen; brain 3.31975
COLGALT2 collagen beta(1-O)galactosyltransferase 2 3.31586
SPX spexin hormone 3.30344
ZZZ3 zinc finger, ZZ-type containing 3 3.29331
SUCO SUN domain containing ossification factor 3.28642
UFM1 ubiquitin-fold modifier 1 3.27434
CCL22 chemokine (C-C motif) ligand 22 3.24317
KCMF1 potassium channel modulatory factor 1 3.23212
SLC43A1 solute carrier family 43 (amino acid system L transporter), member 1 3.2202
PKIG protein kinase (cAMP-dependent, catalytic) inhibitor gamma 3.2163
STX8 syntaxin 8 3.21484
CCPG1 cell cycle progression 1 3.214
HSPA13 heat shock protein 70kDa family, member 13 3.21267
KCTD5 potassium channel tetramerization domain containing 5 3.20607
PLIN2 perilipin 2 3.20314
SNAP25 synaptosomal-associated protein, 25kDa 3.19367
IFI6 interferon, alpha-inducible protein 6 3.17499
ARFGAP3 ADP-ribosylation factor GTPase activating protein 3 3.17198
METTL25B methyltransferase like 25B 3.168
BABAM2 BRISC and BRCA1 A complex member 2 3.16274
LRRC8D leucine rich repeat containing 8 family, member D 3.15217
MAP1B microtubule-associated protein 1B 3.15055
SLC30A1 solute carrier family 30 (zinc transporter), member 1 3.13596
UFSP2 UFM1-specific peptidase 2 3.12695
LOC128125822 uncharacterized LOC128125822 3.12581
OARD1 O-acyl-ADP-ribose deacylase 1 3.0929
CREB5 cAMP responsive element binding protein 5 3.08582
MAN2A1 mannosidase, alpha, class 2A, member 1 3.08451
IGFBP1 insulin-like growth factor binding protein 1 3.0617
PMAIP1 phorbol-12-myristate-13-acetate-induced protein 1 3.05576
DGKD diacylglycerol kinase, delta 130kDa 3.04928
BDNF brain-derived neurotrophic factor 3.04809
CD55 CD55 molecule, decay accelerating factor for complement (Cromer blood group) 3.04755
DDX50 DEAD (Asp-Glu-Ala-Asp) box polypeptide 50 3.04332
ANKRA2 ankyrin repeat, family A (RFXANK-like), 2 3.04119
SDC4 syndecan 4 3.03935
NMNAT2 nicotinamide nucleotide adenylyltransferase 2 3.03481
PRELID3A PRELI domain containing 3A 3.02194
SLC35G2 solute carrier family 35, member G2 3.01782
MAP1LC3B microtubule-associated protein 1 light chain 3 beta 3.01302
GCC1 GRIP and coiled-coil domain containing 1 2.99546
SCFD1 sec1 family domain containing 1 2.99177
CDK7 cyclin-dependent kinase 7 2.97119
DHRS4 dehydrogenase/reductase (SDR family) member 4 2.96927
ATG101 autophagy related 101 2.96474
CASK calcium/calmodulin-dependent serine protein kinase (MAGUK family) 2.96447
EIF2B2 eukaryotic translation initiation factor 2B, subunit 2 beta, 39kDa 2.96273
GDF5 growth differentiation factor 5 2.96098
CIRBP cold inducible RNA binding protein 2.95542
PAPPA2 pappalysin 2 2.94798
NT5E 5'-nucleotidase, ecto (CD73) 2.94655
MAFG v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog G 2.94346
TESC tescalcin 2.94312
DOCK6 dedicator of cytokinesis 6 2.94203
MOK MOK protein kinase 2.9398
B4GALT3 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 3 2.93645
NIBAN1 niban apoptosis regulator 1 2.93146
IFT20 intraflagellar transport 20 2.9293
ACTMAP actin maturation protease 2.92684
GALE UDP-galactose-4-epimerase 2.92659
CHRM3 cholinergic receptor, muscarinic 3 2.92413
ARL4D ADP-ribosylation factor-like 4D 2.91768
SOD3 superoxide dismutase 3, extracellular 2.90885
CAPN6 calpain 6 2.90539
CCDC90B coiled-coil domain containing 90B 2.90483
KRCC1 lysine-rich coiled-coil 1 2.90295
NAMPT nicotinamide phosphoribosyltransferase 2.89105
LIN7A lin-7 homolog A (C. elegans) 2.88568
EFL1 elongation factor like GTPase 1 2.88282
VIPAS39 VPS33B interacting protein, apical-basolateral polarity regulator, spe-39 homolog 2.87822
TRPV4 transient receptor potential cation channel, subfamily V, member 4 2.87428
CPT1B carnitine palmitoyltransferase 1B (muscle) 2.8692
DECR1 2,4-dienoyl CoA reductase 1, mitochondrial 2.866
PJA2 praja ring finger 2, E3 ubiquitin protein ligase 2.85874
S100P S100 calcium binding protein P 2.85828
GRB14 growth factor receptor-bound protein 14 2.8567
SETD5 SET domain containing 5 2.85502
RAB11FIP2 RAB11 family interacting protein 2 (class I) 2.84804
NFE2L1 nuclear factor, erythroid 2-like 1 2.84302
SCN5A sodium channel, voltage gated, type V alpha subunit 2.83743
RPS6KA2 ribosomal protein S6 kinase, 90kDa, polypeptide 2 2.83581
ACTC1 actin, alpha, cardiac muscle 1 2.83218
SLC50A1 solute carrier family 50 (sugar efflux transporter), member 1 2.81925
DNAJC12 DnaJ (Hsp40) homolog, subfamily C, member 12 2.81446
ZNF23 zinc finger protein 23 2.81444
INPP1 inositol polyphosphate-1-phosphatase 2.81383
MTO1 mitochondrial tRNA translation optimization 1 2.80893
MAFF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F 2.8086
CTF1 cardiotrophin 1 2.80008
IGF2BP2 insulin-like growth factor 2 mRNA binding protein 2 2.79926
GBE1 glucan (1,4-alpha-), branching enzyme 1 2.79371
PLEKHA4 pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 4 2.79341
NGLY1 N-glycanase 1 2.78685
TMEM39A transmembrane protein 39A 2.7864
LIAS lipoic acid synthetase 2.78179
MT1F metallothionein 1F 2.77854
CTBS chitobiase, di-N-acetyl- 2.76662
ANO1 anoctamin 1, calcium activated chloride channel 2.76528
ZBTB38 zinc finger and BTB domain containing 38 2.76145
USO1 USO1 vesicle transport factor 2.75968
WHR1 winged helix repair factor 1 2.75819
P3H1 prolyl 3-hydroxylase 1 2.75739
GNG12 guanine nucleotide binding protein (G protein), gamma 12 2.75602
MBD5 methyl-CpG binding domain protein 5 2.75353
CDCP1 CUB domain containing protein 1 2.74967
PADI2 peptidyl arginine deiminase, type II 2.74843
SLC75A1 solute carrier family 75 member 1 2.74536
CSRNP2 cysteine-serine-rich nuclear protein 2 2.74324
NFKBIB nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta 2.73869
SLC6A9 solute carrier family 6 (neurotransmitter transporter, glycine), member 9 2.73776
NCSTN nicastrin 2.73558
SEMA3B sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3B 2.72127
BDKRB2 bradykinin receptor B2 2.72109
KCNS1 potassium voltage-gated channel, modifier subfamily S, member 1 2.7117
MAPK6 mitogen-activated protein kinase 6 2.71007
SPAG4 sperm associated antigen 4 2.70556
NGF nerve growth factor (beta polypeptide) 2.6959
ADGRG1 adhesion G protein-coupled receptor G1 2.69349
SERP1 stress-associated endoplasmic reticulum protein 1 2.68898
RABGEF1 RAB guanine nucleotide exchange factor (GEF) 1 2.68221
ZNF410 zinc finger protein 410 2.67686
TNFRSF12A tumor necrosis factor receptor superfamily, member 12A 2.67589
SYT1 synaptotagmin I 2.67415
PLCB4 phospholipase C, beta 4 2.67181
MICALL1 MICAL-like 1 2.66338
APOLD1 apolipoprotein L domain containing 1 2.6622
STX18 syntaxin 18 2.65666
UAP1 UDP-N-acetylglucosamine pyrophosphorylase 1 2.65615
NMRK1 nicotinamide riboside kinase 1 2.65126
NUP58 nucleoporin 58 2.64603
SMG5 SMG5 nonsense mediated mRNA decay factor 2.64449
TNNC2 troponin C type 2 (fast) 2.64337
SLC2A10 solute carrier family 2 (facilitated glucose transporter), member 10 2.64035
IQSEC2 IQ motif and Sec7 domain 2 2.6345
PDGFA platelet-derived growth factor alpha polypeptide 2.63427
NGRN neugrin, neurite outgrowth associated 2.62892
AMPH amphiphysin 2.62442
SNAPC2 small nuclear RNA activating complex, polypeptide 2, 45kDa 2.62341
PRDM8 PR domain containing 8 2.61934
SEC63 SEC63 homolog (S. cerevisiae) 2.61724
PPCDC phosphopantothenoylcysteine decarboxylase 2.61723
IDUA iduronidase, alpha-L- 2.617
PRSS3 protease, serine, 3 2.61672
TIPARP TCDD-inducible poly(ADP-ribose) polymerase 2.61558
CA6 carbonic anhydrase VI 2.615
RHOF ras homolog family member F (in filopodia) 2.61338
TARS1 threonyl-tRNA synthetase 1 2.61287
IFNA13 interferon, alpha 13 2.61016
CXCL8 chemokine (C-X-C motif) ligand 8 2.6087
TAGLN3 transgelin 3 2.60329
LOC127933115 uncharacterized LOC127933115 2.6012
TRIP12 thyroid hormone receptor interactor 12 2.5989
STUB1 STIP1 homology and U-box containing protein 1, E3 ubiquitin protein ligase 2.59757
PLAUR plasminogen activator, urokinase receptor 2.59324
BTG1 B-cell translocation gene 1, anti-proliferative 2.59125
SLC35B1 solute carrier family 35, member B1 2.58005
SLC12A5 solute carrier family 12 (potassium/chloride transporter), member 5 2.58002
RBCK1 RanBP-type and C3HC4-type zinc finger containing 1 2.57811
MKNK2 MAP kinase interacting serine/threonine kinase 2 2.57378
GCC2 GRIP and coiled-coil domain containing 2 2.56972
SNCB synuclein, beta 2.56756
CSGALNACT2 chondroitin sulfate N-acetylgalactosaminyltransferase 2 2.5671
GAA glucosidase, alpha; acid 2.56538
PPP1R15A protein phosphatase 1, regulatory subunit 15A 2.56017
MZT2B mitotic spindle organizing protein 2B 2.55523
GRM3 glutamate receptor, metabotropic 3 2.54619
GABARAPL1 GABA(A) receptor-associated protein like 1 2.54614
NOS1AP nitric oxide synthase 1 (neuronal) adaptor protein 2.54565
PDE6G phosphodiesterase 6G, cGMP-specific, rod, gamma 2.54554
ZNF281 zinc finger protein 281 2.54391
SERPINB8 serpin peptidase inhibitor, clade B (ovalbumin), member 8 2.53988
CRAT carnitine O-acetyltransferase 2.53857
RNF41 ring finger protein 41, E3 ubiquitin protein ligase 2.53619
MNAT1 MNAT CDK-activating kinase assembly factor 1 2.53038
RASAL1 RAS protein activator like 1 (GAP1 like) 2.52937
CCSER2 coiled-coil serine-rich protein 2 2.52276
LPAR1 lysophosphatidic acid receptor 1 2.52113
AKTIP AKT interacting protein 2.51469
ERCC1 excision repair cross-complementation group 1 2.51313
TNIP1 TNFAIP3 interacting protein 1 2.50962
STYXL1 serine/threonine/tyrosine interacting-like 1 2.50922
ARMCX3 armadillo repeat containing, X-linked 3 2.50727
SSR2 signal sequence receptor, beta (translocon-associated protein beta) 2.50507
UNC5B unc-5 homolog B (C. elegans) 2.5048
CYP27B1 cytochrome P450, family 27, subfamily B, polypeptide 1 2.50124
RTCA RNA 3'-terminal phosphate cyclase 2.50032
PHF21A PHD finger protein 21A 2.4956
TM9SF3 transmembrane 9 superfamily member 3 2.48914
TSPAN5 tetraspanin 5 2.48705
IRS1 insulin receptor substrate 1 2.48633
GLRX2 glutaredoxin 2 2.48237
HOMER1 homer scaffolding protein 1 2.48163
RAB3IL1 RAB3A interacting protein (rabin3)-like 1 2.47494
HDLBP high density lipoprotein binding protein 2.47248
CNGA1 cyclic nucleotide gated channel alpha 1 2.47084
DMWD dystrophia myotonica, WD repeat containing 2.46592
NDUFS2 NADH dehydrogenase (ubiquinone) Fe-S protein 2, 49kDa (NADH-coenzyme Q reductase) 2.46556
LMO4 LIM domain only 4 2.46441
CDK17 cyclin-dependent kinase 17 2.46188
CSGALNACT1 chondroitin sulfate N-acetylgalactosaminyltransferase 1 2.45929
KMT5B lysine methyltransferase 5B 2.45833
APLNR apelin receptor 2.45797
ITPRID2 ITPR interacting domain containing 2 2.45598
IL3RA interleukin 3 receptor, alpha (low affinity) 2.45429
ABCG1 ATP-binding cassette, sub-family G (WHITE), member 1 2.45231
NBAS neuroblastoma amplified sequence 2.45106
SERPINA3 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3 2.44997
FBN2 fibrillin 2 2.44898
MT1M metallothionein 1M 2.44008
LYRM1 LYR motif containing 1 2.43979
IER2 immediate early response 2 2.43838
KIZ kizuna centrosomal protein 2.43507
CCS copper chaperone for superoxide dismutase 2.43365
GRIN2C glutamate receptor, ionotropic, N-methyl D-aspartate 2C 2.43298
DYNC1LI2 dynein, cytoplasmic 1, light intermediate chain 2 2.43009
CTAGE8 CTAGE family, member 8 2.4287
IL1RAPL1 interleukin 1 receptor accessory protein-like 1 2.42841
WDR41 WD repeat domain 41 2.42299
MBD1 methyl-CpG binding domain protein 1 2.41909
RNF103 ring finger protein 103 2.41564
MTIF2 mitochondrial translational initiation factor 2 2.41273
UNC13D unc-13 homolog D (C. elegans) 2.41061
P4HB prolyl 4-hydroxylase, beta polypeptide 2.40927
TRIM2 tripartite motif containing 2 2.40841
NTRK2 neurotrophic tyrosine kinase, receptor, type 2 2.40463
DYRK4 dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 4 2.4027
CREB3L2 cAMP responsive element binding protein 3-like 2 2.40228
PAIP2B poly(A) binding protein interacting protein 2B 2.39943
PDE1A phosphodiesterase 1A, calmodulin-dependent 2.39698
INHBB inhibin, beta B 2.39619
RGS7 regulator of G-protein signaling 7 2.39344
BUD31 BUD31 homolog (S. cerevisiae) 2.39215
DENND2A DENN/MADD domain containing 2A 2.38831
MYL11 myosin light chain 11 2.38783
GLG1 golgi glycoprotein 1 2.38771
SYNE3 spectrin repeat containing, nuclear envelope family member 3 2.38655
TNNI1 troponin I type 1 (skeletal, slow) 2.38563
MMP1 matrix metallopeptidase 1 2.38203
ADAM9 ADAM metallopeptidase domain 9 2.38038
APOBEC2 apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 2 2.38
PENK proenkephalin 2.37856
SYN1 synapsin I 2.37717
APOD apolipoprotein D 2.37359
TRPA1 transient receptor potential cation channel, subfamily A, member 1 2.37336
AMZ2 archaelysin family metallopeptidase 2 2.37156
HSD3B2 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 2 2.37153
GADD45A growth arrest and DNA-damage-inducible, alpha 2.36866
SCCPDH saccharopine dehydrogenase (putative) 2.36861
EREG epiregulin 2.36771
KIFC3 kinesin family member C3 2.36633
CLTCL1 clathrin, heavy chain-like 1 2.36163
HSPB6 heat shock protein, alpha-crystallin-related, B6 2.361
HSPBAP1 HSPB (heat shock 27kDa) associated protein 1 2.35983
ARHGAP29 Rho GTPase activating protein 29 2.35783
CCT6B chaperonin containing TCP1, subunit 6B (zeta 2) 2.35629
SYNGR4 synaptogyrin 4 2.35493
NDEL1 nudE neurodevelopment protein 1-like 1 2.35466
INTS6 integrator complex subunit 6 2.35454
AVEN apoptosis, caspase activation inhibitor 2.35266
SMOX spermine oxidase 2.35227
BCL10 B-cell CLL/lymphoma 10 2.35184
MT1G metallothionein 1G 2.34636
ZNF862 zinc finger protein 862 2.34558
SLC6A11 solute carrier family 6 (neurotransmitter transporter), member 11 2.34234
KYAT3 kynurenine aminotransferase 3 2.33927
ZCWPW1 zinc finger, CW type with PWWP domain 1 2.33877
FUT8 fucosyltransferase 8 (alpha (1,6) fucosyltransferase) 2.33839
TXNDC15 thioredoxin domain containing 15 2.33832
HAL histidine ammonia-lyase 2.33788
ENOX1 ecto-NOX disulfide-thiol exchanger 1 2.33775
NSUN3 NOP2/Sun domain family, member 3 2.33746
HGD homogentisate 1,2-dioxygenase 2.33468
ZNF358 zinc finger protein 358 2.33117
SLC22A17 solute carrier family 22, member 17 2.32703
ATXN1 ataxin 1 2.32522
SCG5 secretogranin V 2.32504
ST6GALNAC2 ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2 2.32426
RIOK2 RIO kinase 2 2.32371
DLGAP3 discs, large (Drosophila) homolog-associated protein 3 2.31882
RWDD2B RWD domain containing 2B 2.31419
SV2B synaptic vesicle glycoprotein 2B 2.31388
CLCF1 cardiotrophin-like cytokine factor 1 2.31333
SLC38A1 solute carrier family 38, member 1 2.31298
KATNA1 katanin p60 (ATPase containing) subunit A 1 2.30989
EP300 E1A binding protein p300 2.30811
ARHGAP5 Rho GTPase activating protein 5 2.30769
EFHC1 EF-hand domain (C-terminal) containing 1 2.30747
PDE1C phosphodiesterase 1C, calmodulin-dependent 70kDa 2.30628
RUNDC3A RUN domain containing 3A 2.30544
RAB13 RAB13, member RAS oncogene family 2.30444
NFATC4 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 4 2.30376
B3GNT3 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 3 2.30268
ZNF638 zinc finger protein 638 2.29946
DUSP6 dual specificity phosphatase 6 2.29902
MYL4 myosin, light chain 4, alkali; atrial, embryonic 2.29798
ACADVL acyl-CoA dehydrogenase, very long chain 2.29501
WHRN whirlin 2.29479
ADM adrenomedullin 2.2934
SLC67A1 solute carrier family 67 member 1 2.29189
LGALS1 lectin, galactoside-binding, soluble, 1 2.28967
GOLGB1 golgin B1 2.28846
MEF2D myocyte enhancer factor 2D 2.28564
ECI1 enoyl-CoA delta isomerase 1 2.2852
CYP39A1 cytochrome P450, family 39, subfamily A, polypeptide 1 2.28418
EPS8 epidermal growth factor receptor pathway substrate 8 2.28125
BIRC2 baculoviral IAP repeat containing 2 2.2788
IGFBP4 insulin-like growth factor binding protein 4 2.27809
DUSP5 dual specificity phosphatase 5 2.27613
CDK19 cyclin-dependent kinase 19 2.27441
NME7 NME/NM23 family member 7 2.27413
FAM114A1 family with sequence similarity 114, member A1 2.27313
KRT33B keratin 33B, type I 2.27099
ATP4A ATPase, H+/K+ exchanging, alpha polypeptide 2.2698
PTX3 pentraxin 3, long 2.26872
MPST mercaptopyruvate sulfurtransferase 2.26613
ECM1 extracellular matrix protein 1 2.26449
PLA2G4C phospholipase A2, group IVC (cytosolic, calcium-independent) 2.2615
HSP90B1 heat shock protein 90kDa beta (Grp94), member 1 2.25608
PRSS2 protease, serine, 2 (trypsin 2) 2.25565
IL11 interleukin 11 2.25371
RTN2 reticulon 2 2.25031
PHYHIP phytanoyl-CoA 2-hydroxylase interacting protein 2.24946
COL5A2 collagen, type V, alpha 2 2.24933
PLPP3 phospholipid phosphatase 3 2.248
AGTPBP1 ATP/GTP binding protein 1 2.24788
QSOX1 quiescin Q6 sulfhydryl oxidase 1 2.2434
IFT88 intraflagellar transport 88 2.24331
ACVR1 activin A receptor, type I 2.23776
HKDC1 hexokinase domain containing 1 2.23717
PORCN porcupine homolog (Drosophila) 2.23625
OXCT2 3-oxoacid CoA transferase 2 2.23585
NCK2 NCK adaptor protein 2 2.23446
VGLL4 vestigial-like family member 4 2.23405
FOSB FBJ murine osteosarcoma viral oncogene homolog B 2.2339
CHGB chromogranin B 2.22742
ARL8B ADP-ribosylation factor-like 8B 2.22482
BCORL1 BCL6 corepressor-like 1 2.22349
ALDH2 aldehyde dehydrogenase 2 family (mitochondrial) 2.22327
MAP4K4 mitogen-activated protein kinase kinase kinase kinase 4 2.22313
DACH1 dachshund family transcription factor 1 2.22089
PARP6 poly (ADP-ribose) polymerase family, member 6 2.22073
NAT9 N-acetyltransferase 9 (GCN5-related, putative) 2.22071
TMEM47 transmembrane protein 47 2.21996
SEL1L3 sel-1 suppressor of lin-12-like 3 (C. elegans) 2.21796
USP3 ubiquitin specific peptidase 3 2.21145
NT5M 5',3'-nucleotidase, mitochondrial 2.20928
TTC17 tetratricopeptide repeat domain 17 2.20767
EFEMP2 EGF containing fibulin-like extracellular matrix protein 2 2.20626
POPDC3 popeye domain containing 3 2.20405
C6ORF89 chromosome 6 open reading frame 89 2.20379
LETMD1 LETM1 domain containing 1 2.20204
CNOT7 CCR4-NOT transcription complex, subunit 7 2.20144
FSTL1 follistatin-like 1 2.20071
GHITM growth hormone inducible transmembrane protein 2.19877
TMEM59 transmembrane protein 59 2.19801
YY1AP1 YY1 associated protein 1 2.19786
TSTD1 thiosulfate sulfurtransferase (rhodanese)-like domain containing 1 2.19572
SNX6 sorting nexin 6 2.19431
RDH16 retinol dehydrogenase 16 (all-trans) 2.19314
PIGK phosphatidylinositol glycan anchor biosynthesis, class K 2.19306
GABRB1 gamma-aminobutyric acid (GABA) A receptor, beta 1 2.19272
OLAH oleoyl-ACP hydrolase 2.19234
VWF von Willebrand factor 2.19165
ZC3H15 zinc finger CCCH-type containing 15 2.19123
WNT11 wingless-type MMTV integration site family, member 11 2.18968
S100A12 S100 calcium binding protein A12 2.18754
MYL6B myosin, light chain 6B, alkali, smooth muscle and non-muscle 2.18701
HBG1 hemoglobin, gamma A 2.18406
CABYR calcium binding tyrosine-(Y)-phosphorylation regulated 2.18373
MZT2A mitotic spindle organizing protein 2A 2.18312
PRKACB protein kinase, cAMP-dependent, catalytic, beta 2.18222
ARID3B AT rich interactive domain 3B (BRIGHT-like) 2.18054
GABRA1 gamma-aminobutyric acid (GABA) A receptor, alpha 1 2.17984
LPGAT1 lysophosphatidylglycerol acyltransferase 1 2.17826
LRP10 low density lipoprotein receptor-related protein 10 2.17673
MUC13 mucin 13, cell surface associated 2.17582
CBX4 chromobox homolog 4 2.1757
PXDC1 PX domain containing 1 2.17104
PSD3 pleckstrin and Sec7 domain containing 3 2.16732
ZBTB20 zinc finger and BTB domain containing 20 2.1659
EIF4G3 eukaryotic translation initiation factor 4 gamma, 3 2.16583
ANGPTL4 angiopoietin-like 4 2.16444
NHLH1 nescient helix loop helix 1 2.16443
NSG2 neuronal vesicle trafficking associated 2 2.16405
PAPPA pregnancy-associated plasma protein A, pappalysin 1 2.16265
AKAP3 A kinase (PRKA) anchor protein 3 2.16143
ISG20 interferon stimulated exonuclease gene 20kDa 2.16126
PCSK1 proprotein convertase subtilisin/kexin type 1 2.16026
KRT9 keratin 9, type I 2.15591
SPG11 spastic paraplegia 11 (autosomal recessive) 2.15188
EMC9 ER membrane protein complex subunit 9 2.15113
FOXO4 forkhead box O4 2.14839
ATP11B ATPase, class VI, type 11B 2.14675
DRAP1 DR1-associated protein 1 (negative cofactor 2 alpha) 2.14617
GCLM glutamate-cysteine ligase, modifier subunit 2.14478
ARID3A AT rich interactive domain 3A (BRIGHT-like) 2.14475
FNDC3B fibronectin type III domain containing 3B 2.14332
CAPRIN2 caprin family member 2 2.14328
MRPL30 mitochondrial ribosomal protein L30 2.14306
TFB1M transcription factor B1, mitochondrial 2.14206
PTPN4 protein tyrosine phosphatase, non-receptor type 4 (megakaryocyte) 2.13875
PAMR1 peptidase domain containing associated with muscle regeneration 1 2.13762
CRELD2 cysteine-rich with EGF-like domains 2 2.13563
ALG5 ALG5, dolichyl-phosphate beta-glucosyltransferase 2.13191
TRAF5 TNF receptor-associated factor 5 2.13073
EML2 echinoderm microtubule associated protein like 2 2.13066
SMR3B submaxillary gland androgen regulated protein 3B 2.12635
PRKRA protein kinase, interferon-inducible double stranded RNA dependent activator 2.12577
SNAPC1 small nuclear RNA activating complex, polypeptide 1, 43kDa 2.1253
TNP1 transition protein 1 (during histone to protamine replacement) 2.12461
EIF1 eukaryotic translation initiation factor 1 2.12436
CEBPD CCAAT/enhancer binding protein (C/EBP), delta 2.12433
PPIE peptidylprolyl isomerase E (cyclophilin E) 2.12419
PGM3 phosphoglucomutase 3 2.12304
DNAL4 dynein, axonemal, light chain 4 2.12213
OR51E2 olfactory receptor, family 51, subfamily E, member 2 2.12046
RIOK3 RIO kinase 3 2.11998
GMFG glia maturation factor, gamma 2.11954
CYP11B2 cytochrome P450, family 11, subfamily B, polypeptide 2 2.11932
KCNN3 potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 3 2.11895
GGPS1 geranylgeranyl diphosphate synthase 1 2.1181
ELF5 E74-like factor 5 (ets domain transcription factor) 2.11675
SRP54 signal recognition particle 54kDa 2.11649
SEZ6L2 seizure related 6 homolog (mouse)-like 2 2.11633
SEMA5A sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A 2.11622
WBP1L WW domain binding protein 1-like 2.11452
TALDO1 transaldolase 1 2.10895
ERP29 endoplasmic reticulum protein 29 2.10754
ADGRG3 adhesion G protein-coupled receptor G3 2.10635
HDAC4 histone deacetylase 4 2.10505
SLC1A2 solute carrier family 1 (glial high affinity glutamate transporter), member 2 2.10496
XPC xeroderma pigmentosum, complementation group C 2.10434
IFI35 interferon-induced protein 35 2.10433
ALOXE3 arachidonate lipoxygenase 3 2.10386
CANT1 calcium activated nucleotidase 1 2.10331
SLC6A7 solute carrier family 6 (neurotransmitter transporter), member 7 2.10289
ABI2 abl-interactor 2 2.10161
VEGFA vascular endothelial growth factor A 2.10108
CAV3 caveolin 3 2.10077
MYL1 myosin, light chain 1, alkali; skeletal, fast 2.10046
CEP63 centrosomal protein 63kDa 2.10042
SRPK3 SRSF protein kinase 3 2.10041
MYOZ1 myozenin 1 2.0988
TPBG trophoblast glycoprotein 2.09874
PRND prion protein 2 (dublet) 2.0987
WDR19 WD repeat domain 19 2.09826
RAP1GAP RAP1 GTPase activating protein 2.0936
HSD17B2 hydroxysteroid (17-beta) dehydrogenase 2 2.09348
TGM5 transglutaminase 5 2.09209
ATXN3 ataxin 3 2.0909
ASB8 ankyrin repeat and SOCS box containing 8 2.08828
TPD52L1 tumor protein D52-like 1 2.08698
DHRS7 dehydrogenase/reductase (SDR family) member 7 2.0866
SHC1 SHC (Src homology 2 domain containing) transforming protein 1 2.08563
ZNF778 zinc finger protein 778 2.08401
HSPA5 heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) 2.08333
KCNA2 potassium channel, voltage gated shaker related subfamily A, member 2 2.08332
BCL2L13 BCL2-like 13 (apoptosis facilitator) 2.08028
ERBIN erbb2 interacting protein 2.07897
MNT MAX network transcriptional repressor 2.07833
SNAI1 snail family zinc finger 1 2.07814
WSCD1 WSC domain containing 1 2.07593
TNIK TRAF2 and NCK interacting kinase 2.07472
RNF24 ring finger protein 24 2.07389
MKRN1 makorin ring finger protein 1 2.07104
SMPD3 sphingomyelin phosphodiesterase 3, neutral membrane (neutral sphingomyelinase II) 2.07088
HSF4 heat shock transcription factor 4 2.06663
CRBN cereblon 2.06611
DNAJB14 DnaJ (Hsp40) homolog, subfamily B, member 14 2.0628
GRIA2 glutamate receptor, ionotropic, AMPA 2 2.06175
MPPED1 metallophosphoesterase domain containing 1 2.06083
SPAG7 sperm associated antigen 7 2.05992
EZH2 enhancer of zeste 2 polycomb repressive complex 2 subunit 2.05918
AQP2 aquaporin 2 (collecting duct) 2.05756
SLC1A5 solute carrier family 1 (neutral amino acid transporter), member 5 2.0572
UFL1 UFM1-specific ligase 1 2.05562
SAGE1 sarcoma antigen 1 2.05494
PRR16 proline rich 16 2.05391
ASAP2 ArfGAP with SH3 domain, ankyrin repeat and PH domain 2 2.05388
ACTR6 ARP6 actin-related protein 6 homolog (yeast) 2.05346
SLC39A14 solute carrier family 39 (zinc transporter), member 14 2.05292
PKNOX2 PBX/knotted 1 homeobox 2 2.05187
COPB1 coatomer protein complex, subunit beta 1 2.05178
MT1H metallothionein 1H 2.05109
THYN1 thymocyte nuclear protein 1 2.05072
CRELD1 cysteine-rich with EGF-like domains 1 2.05063
KLHDC4 kelch domain containing 4 2.05012
EPS8L3 EPS8-like 3 2.04551
OS9 osteosarcoma amplified 9, endoplasmic reticulum lectin 2.04471
THBS4 thrombospondin 4 2.04353
PPARG peroxisome proliferator-activated receptor gamma 2.04256
BRAF B-Raf proto-oncogene, serine/threonine kinase 2.04085
WDR13 WD repeat domain 13 2.04042
CCL3L3 chemokine (C-C motif) ligand 3-like 3 2.0392
TFF2 trefoil factor 2 2.03479
FIBP fibroblast growth factor (acidic) intracellular binding protein 2.03458
NAV3 neuron navigator 3 2.03358
CRISPLD2 cysteine-rich secretory protein LCCL domain containing 2 2.03347
LAMC2 laminin, gamma 2 2.03339
PLCD1 phospholipase C, delta 1 2.03325
GNG11 guanine nucleotide binding protein (G protein), gamma 11 2.03288
DUSP13A dual specificity phosphatase 13A 2.03058
TXLNA taxilin alpha 2.0298
TMEM260 transmembrane protein 260 2.02963
NQO1 NAD(P)H dehydrogenase, quinone 1 2.02878
ATP9B ATPase, class II, type 9B 2.02274
TMCC2 transmembrane and coiled-coil domain family 2 2.02237
SPTAN1 spectrin, alpha, non-erythrocytic 1 2.02119
TRIM8 tripartite motif containing 8 2.01946
ZNF419 zinc finger protein 419 2.01918
KLHL9 kelch-like family member 9 2.01895
LCMT1 leucine carboxyl methyltransferase 1 2.01857
PLPPR4 phospholipid phosphatase related 4 2.01718
CST2 cystatin SA 2.01658
TERF2 telomeric repeat binding factor 2 2.0163
TOM1 target of myb1 (chicken) 2.01564
LHFPL2 lipoma HMGIC fusion partner-like 2 2.01443
TRIOBP TRIO and F-actin binding protein 2.01213
NFU1 NFU1 iron-sulfur cluster scaffold 2.01081
NPDC1 neural proliferation, differentiation and control, 1 2.00351

decreased expression

Symbol Name Standardized Value
MSMO1 methylsterol monooxygenase 1 -10.0
OAT ornithine aminotransferase -9.56932
HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) -8.20659
COG7 component of oligomeric golgi complex 7 -7.98423
TCTA T-cell leukemia translocation altered -7.83581
UQCR10 ubiquinol-cytochrome c reductase, complex III subunit X -7.31639
MCM3 minichromosome maintenance complex component 3 -7.20459
PCNA proliferating cell nuclear antigen -7.18572
NSDHL NAD(P) dependent steroid dehydrogenase-like -7.0496
FEN1 flap structure-specific endonuclease 1 -6.8508
TARBP1 TAR (HIV-1) RNA binding protein 1 -6.67702
DCK deoxycytidine kinase -6.2387
TMEM109 transmembrane protein 109 -6.18365
HSPA8 heat shock 70kDa protein 8 -6.16283
NUP85 nucleoporin 85kDa -5.93136
MCM6 minichromosome maintenance complex component 6 -5.78096
STMN1 stathmin 1 -5.67072
INSIG1 insulin induced gene 1 -5.66699
HSPB1 heat shock 27kDa protein 1 -5.49501
MCM4 minichromosome maintenance complex component 4 -5.4755
C1QBP complement component 1, q subcomponent binding protein -5.29004
IDI1 isopentenyl-diphosphate delta isomerase 1 -5.14929
TRIP13 thyroid hormone receptor interactor 13 -5.12585
MCM10 minichromosome maintenance complex component 10 -5.07483
ASF1B anti-silencing function 1B histone chaperone -5.07107
KIF20A kinesin family member 20A -5.0225
CDK1 cyclin-dependent kinase 1 -4.95411
NT5DC2 5'-nucleotidase domain containing 2 -4.88208
PUF60 poly-U binding splicing factor 60KDa -4.82855
ELAC2 elaC ribonuclease Z 2 -4.74841
GINS2 GINS complex subunit 2 (Psf2 homolog) -4.732
CCNA2 cyclin A2 -4.71479
SRSF2 serine/arginine-rich splicing factor 2 -4.68898
CHAF1A chromatin assembly factor 1, subunit A (p150) -4.6329
DNMT1 DNA (cytosine-5-)-methyltransferase 1 -4.61844
RFC3 replication factor C (activator 1) 3, 38kDa -4.60271
ERCC6L excision repair cross-complementation group 6-like -4.5666
BAG3 BCL2-associated athanogene 3 -4.56561
RPA3 replication protein A3, 14kDa -4.53192
NUSAP1 nucleolar and spindle associated protein 1 -4.50917
MCM7 minichromosome maintenance complex component 7 -4.49958
ADH5 alcohol dehydrogenase 5 (class III), chi polypeptide -4.45969
BZW2 basic leucine zipper and W2 domains 2 -4.44578
NUP160 nucleoporin 160kDa -4.4405
PARP1 poly (ADP-ribose) polymerase 1 -4.42684
DHCR24 24-dehydrocholesterol reductase -4.41888
MCM5 minichromosome maintenance complex component 5 -4.3991
DHFR dihydrofolate reductase -4.38896
FOXM1 forkhead box M1 -4.33976
GINS1 GINS complex subunit 1 (Psf1 homolog) -4.33351
SUV39H1 suppressor of variegation 3-9 homolog 1 (Drosophila) -4.27265
GTF3C2 general transcription factor IIIC, polypeptide 2, beta 110kDa -4.25683
CD58 CD58 molecule -4.24363
POLR2L polymerase (RNA) II (DNA directed) polypeptide L, 7.6kDa -4.22115
PAFAH1B3 platelet-activating factor acetylhydrolase 1b, catalytic subunit 3 (29kDa) -4.20784
AKT1 v-akt murine thymoma viral oncogene homolog 1 -4.20368
POLA2 polymerase (DNA directed), alpha 2, accessory subunit -4.18751
MYBL2 v-myb avian myeloblastosis viral oncogene homolog-like 2 -4.18491
CDC20 cell division cycle 20 -4.18158
MSH2 mutS homolog 2 -4.17829
GDE1 glycerophosphodiester phosphodiesterase 1 -4.16437
PSRC1 proline/serine-rich coiled-coil 1 -4.1432
PRPF4 pre-mRNA processing factor 4 -4.13812
SLC2A6 solute carrier family 2 (facilitated glucose transporter), member 6 -4.13731
NLRP2B NLR family pyrin domain containing 2B -4.13689
CRYZ crystallin, zeta (quinone reductase) -4.13204
TIMELESS timeless circadian clock -4.12953
GINS3 GINS complex subunit 3 (Psf3 homolog) -4.12765
PGRMC1 progesterone receptor membrane component 1 -4.12376
MAD2L1 MAD2 mitotic arrest deficient-like 1 (yeast) -4.11586
CCNF cyclin F -4.08854
HSPE1 heat shock 10kDa protein 1 -4.08797
TK1 thymidine kinase 1, soluble -4.08526
UNG uracil-DNA glycosylase -4.07241
G3BP1 GTPase activating protein (SH3 domain) binding protein 1 -4.07125
BIRC5 baculoviral IAP repeat containing 5 -4.02866
HMG20B high mobility group 20B -4.01472
SNRNP25 small nuclear ribonucleoprotein 25kDa (U11/U12) -4.00297
SH3D19 SH3 domain containing 19 -3.98508
ADI1 acireductone dioxygenase 1 -3.97197
ADRB2 adrenoceptor beta 2, surface -3.94527
RBM14-RBM4 RBM14-RBM4 readthrough -3.92294
SESN1 sestrin 1 -3.92077
KIF11 kinesin family member 11 -3.90599
POLE3 polymerase (DNA directed), epsilon 3, accessory subunit -3.90174
NUP62 nucleoporin 62kDa -3.89438
DDX39A DEAD (Asp-Glu-Ala-Asp) box polypeptide 39A -3.88506
WDR77 WD repeat domain 77 -3.8796
B4GAT1 beta-1,4-glucuronyltransferase 1 -3.87294
CYCS cytochrome c, somatic -3.8558
ZDHHC6 zinc finger, DHHC-type containing 6 -3.83856
ZNF813 zinc finger protein 813 -3.8222
PAGR1 PAXIP1 associated glutamate-rich protein 1 -3.79369
UBR7 ubiquitin protein ligase E3 component n-recognin 7 (putative) -3.78593
LAS1L LAS1-like (S. cerevisiae) -3.78575
UXT ubiquitously-expressed, prefoldin-like chaperone -3.78439
THEM6 thioesterase superfamily member 6 -3.75954
DNAAF5 dynein, axonemal, assembly factor 5 -3.74655
LRIG1 leucine-rich repeats and immunoglobulin-like domains 1 -3.73589
SQLE squalene epoxidase -3.73349
PRR15L proline rich 15-like -3.70386
HMGCR 3-hydroxy-3-methylglutaryl-CoA reductase -3.69278
CCNB1 cyclin B1 -3.68937
JPT2 Jupiter microtubule associated homolog 2 -3.68384
COMMD9 COMM domain containing 9 -3.67118
UBE3C ubiquitin protein ligase E3C -3.6633
PFAS phosphoribosylformylglycinamidine synthase -3.65628
S100A4 S100 calcium binding protein A4 -3.65231
KIF18B kinesin family member 18B -3.64032
POLR3K polymerase (RNA) III (DNA directed) polypeptide K, 12.3 kDa -3.63315
RRM1 ribonucleotide reductase M1 -3.63167
AURKB aurora kinase B -3.6249
HTD2 hydroxyacyl-thioester dehydratase type 2 -3.61939
HAT1 histone acetyltransferase 1 -3.61001
NASP nuclear autoantigenic sperm protein (histone-binding) -3.60811
MRPS7 mitochondrial ribosomal protein S7 -3.56669
MRS2 MRS2 magnesium transporter -3.55523
CPNE3 copine III -3.53988
GRWD1 glutamate-rich WD repeat containing 1 -3.53514
MRPL12 mitochondrial ribosomal protein L12 -3.53186
DNAJA1 DnaJ (Hsp40) homolog, subfamily A, member 1 -3.52499
COPS7B COP9 signalosome subunit 7B -3.52423
TSPAN6 tetraspanin 6 -3.51624
DUT deoxyuridine triphosphatase -3.51424
POLR2K polymerase (RNA) II (DNA directed) polypeptide K, 7.0kDa -3.5087
MSH6 mutS homolog 6 -3.50858
DHX9 DEAH (Asp-Glu-Ala-His) box helicase 9 -3.49494
RRM2 ribonucleotide reductase M2 -3.48706
CCDC86 coiled-coil domain containing 86 -3.47682
CETN2 centrin, EF-hand protein, 2 -3.45336
TCERG1 transcription elongation regulator 1 -3.45245
CENPI centromere protein I -3.44389
NCAPH non-SMC condensin I complex, subunit H -3.4333
TMEM50A transmembrane protein 50A -3.42955
TMX1 thioredoxin-related transmembrane protein 1 -3.41351
ACYP1 acylphosphatase 1, erythrocyte (common) type -3.40943
TRAPPC3 trafficking protein particle complex 3 -3.39987
SNRPA small nuclear ribonucleoprotein polypeptide A -3.39927
FXN frataxin -3.39074
HSPA1A heat shock 70kDa protein 1A -3.38713
PYDC1 PYD (pyrin domain) containing 1 -3.37919
RFC5 replication factor C (activator 1) 5, 36.5kDa -3.37833
DCTPP1 dCTP pyrophosphatase 1 -3.37184
PSMD3 proteasome (prosome, macropain) 26S subunit, non-ATPase, 3 -3.36468
UBAP2L ubiquitin associated protein 2-like -3.36099
KBTBD4 kelch repeat and BTB (POZ) domain containing 4 -3.35831
TUBA1B tubulin, alpha 1b -3.33708
ELOVL6 ELOVL fatty acid elongase 6 -3.33594
SRSF3 serine/arginine-rich splicing factor 3 -3.33584
PGAM4 phosphoglycerate mutase family member 4 -3.32696
NDUFA8 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 8, 19kDa -3.30415
NELFCD negative elongation factor complex member C/D -3.296
GPD1L glycerol-3-phosphate dehydrogenase 1-like -3.28912
RFX5 regulatory factor X, 5 (influences HLA class II expression) -3.28909
TUBB6 tubulin, beta 6 class V -3.27854
HNRNPA2B1 heterogeneous nuclear ribonucleoprotein A2/B1 -3.2768
FASTKD3 FAST kinase domains 3 -3.26169
ALDOC aldolase C, fructose-bisphosphate -3.25533
GEMIN4 gem (nuclear organelle) associated protein 4 -3.24981
POP5 processing of precursor 5, ribonuclease P/MRP subunit (S. cerevisiae) -3.24606
PYCR3 pyrroline-5-carboxylate reductase 3 -3.24588
NEIL3 nei endonuclease VIII-like 3 (E. coli) -3.2409
GLO1 glyoxalase I -3.22352
PTGER4 prostaglandin E receptor 4 (subtype EP4) -3.22042
SPIN2B spindlin family, member 2B -3.21839
UBAC1 UBA domain containing 1 -3.20502
ELP5 elongator acetyltransferase complex subunit 5 -3.20003
ORC6 origin recognition complex, subunit 6 -3.19705
COX16 COX16 cytochrome c oxidase assembly homolog (S. cerevisiae) -3.19239
DROSHA drosha, ribonuclease type III -3.18882
ZNF557 zinc finger protein 557 -3.17956
LSM3 LSM3 homolog, U6 small nuclear RNA associated (S. cerevisiae) -3.17213
RBM12 RNA binding motif protein 12 -3.1716
POLA1 polymerase (DNA directed), alpha 1, catalytic subunit -3.16807
FN3KRP fructosamine 3 kinase related protein -3.1664
CDC45 cell division cycle 45 -3.16136
WDCP WD repeat and coiled coil containing -3.15796
HNRNPAB heterogeneous nuclear ribonucleoprotein A/B -3.15736
AKAP8 A kinase (PRKA) anchor protein 8 -3.14986
OIP5 Opa interacting protein 5 -3.14686
CYP51A1 cytochrome P450, family 51, subfamily A, polypeptide 1 -3.14066
ZNF274 zinc finger protein 274 -3.10946
HOXA5 homeobox A5 -3.10636
KCTD12 potassium channel tetramerization domain containing 12 -3.10415
MICA MHC class I polypeptide-related sequence A -3.10128
PRPF31 pre-mRNA processing factor 31 -3.09991
IRAK1 interleukin-1 receptor-associated kinase 1 -3.09573
LMBR1 limb development membrane protein 1 -3.09548
DBR1 debranching RNA lariats 1 -3.09525
LAPTM4B lysosomal protein transmembrane 4 beta -3.09473
MCMBP minichromosome maintenance complex binding protein -3.09179
NAGPA N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase -3.08514
CDC6 cell division cycle 6 -3.08483
SUMO2 small ubiquitin-like modifier 2 -3.08459
BRCA1 breast cancer 1, early onset -3.08342
SS18L2 synovial sarcoma translocation gene on chromosome 18-like 2 -3.08274
ARHGAP11A Rho GTPase activating protein 11A -3.0827
NCAPD3 non-SMC condensin II complex, subunit D3 -3.07867
GTF3C4 general transcription factor IIIC, polypeptide 4, 90kDa -3.07691
STARD7 StAR-related lipid transfer (START) domain containing 7 -3.07488
DSN1 DSN1, MIS12 kinetochore complex component -3.07057
GGA3 golgi-associated, gamma adaptin ear containing, ARF binding protein 3 -3.06202
FASTKD5 FAST kinase domains 5 -3.05906
SNRPE small nuclear ribonucleoprotein polypeptide E -3.05642
NCAPG2 non-SMC condensin II complex, subunit G2 -3.05278
ATRIP ATR interacting protein -3.05024
CLN6 ceroid-lipofuscinosis, neuronal 6, late infantile, variant -3.04709
GTF2A2 general transcription factor IIA, 2, 12kDa -3.04481
FUS FUS RNA binding protein -3.03525
DCTN5 dynactin 5 (p25) -3.03262
RAD51AP1 RAD51 associated protein 1 -3.03243
SAP30L SAP30-like -3.0321
RBMX RNA binding motif protein, X-linked -3.02958
NDUFS3 NADH dehydrogenase (ubiquinone) Fe-S protein 3, 30kDa (NADH-coenzyme Q reductase) -3.0286
ZWINT ZW10 interacting kinetochore protein -3.02603
NSMCE4A non-SMC element 4 homolog A (S. cerevisiae) -3.01833
APEX1 APEX nuclease (multifunctional DNA repair enzyme) 1 -3.01584
PRPF4B pre-mRNA processing factor 4B -3.01376
MRPL16 mitochondrial ribosomal protein L16 -3.00873
RPIA ribose 5-phosphate isomerase A -3.00194
CENPM centromere protein M -2.99929
POLR1A polymerase (RNA) I polypeptide A, 194kDa -2.99802
SLC61A1 solute carrier family 61 member 1 -2.99405
ATAD2 ATPase family, AAA domain containing 2 -2.99355
NDUFA1 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 1, 7.5kDa -2.9874
MGA MGA, MAX dimerization protein -2.98179
TMEM14A transmembrane protein 14A -2.98153
CDC25A cell division cycle 25A -2.9777
CROT carnitine O-octanoyltransferase -2.97425
ACACA acetyl-CoA carboxylase alpha -2.97053
MCM9 minichromosome maintenance complex component 9 -2.9664
MGAT4A mannosyl (alpha-1,3-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase, isozyme A -2.95636
CLN5 ceroid-lipofuscinosis, neuronal 5 -2.95592
ABHD11 abhydrolase domain containing 11 -2.9538
DEXI Dexi homolog (mouse) -2.94945
SKP1 S-phase kinase-associated protein 1 -2.94608
UBE2G2 ubiquitin-conjugating enzyme E2G 2 -2.94515
HACD3 3-hydroxyacyl-CoA dehydratase 3 -2.94502
CCT5 chaperonin containing TCP1, subunit 5 (epsilon) -2.94111
PSMA2 proteasome (prosome, macropain) subunit, alpha type, 2 -2.93798
SNRNP40 small nuclear ribonucleoprotein 40kDa (U5) -2.93384
RPUSD2 RNA pseudouridylate synthase domain containing 2 -2.92866
LSM6 LSM6 homolog, U6 small nuclear RNA associated (S. cerevisiae) -2.92678
SPC25 SPC25, NDC80 kinetochore complex component -2.92596
PGK1 phosphoglycerate kinase 1 -2.92388
SLC25A5 solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 5 -2.92255
TRMT2B tRNA methyltransferase 2 homolog B (S. cerevisiae) -2.90217
PRPS1L1 phosphoribosyl pyrophosphate synthetase 1-like 1 -2.90193
VAMP3 vesicle-associated membrane protein 3 -2.89792
CHCHD7 coiled-coil-helix-coiled-coil-helix domain containing 7 -2.89669
QRICH1 glutamine-rich 1 -2.88849
TUBB tubulin, beta class I -2.88775
BID BH3 interacting domain death agonist -2.88396
TMPO thymopoietin -2.88161
E2F8 E2F transcription factor 8 -2.88066
SDHAF3 succinate dehydrogenase complex assembly factor 3 -2.87883
MYBBP1A MYB binding protein (P160) 1a -2.87677
TIMM8A translocase of inner mitochondrial membrane 8 homolog A (yeast) -2.87515
XRCC5 X-ray repair complementing defective repair in Chinese hamster cells 5 (double-strand-break rejoining) -2.87339
NDUFB6 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 6, 17kDa -2.86584
SIGMAR1 sigma non-opioid intracellular receptor 1 -2.86432
NDRG3 NDRG family member 3 -2.86334
YWHAH tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, eta -2.86226
RRS1 RRS1 ribosome biogenesis regulator homolog (S. cerevisiae) -2.85896
ATXN7L1 ataxin 7-like 1 -2.85519
SRRT serrate, RNA effector molecule -2.85435
DSCC1 DNA replication and sister chromatid cohesion 1 -2.85155
WDR76 WD repeat domain 76 -2.84585
CDK2 cyclin-dependent kinase 2 -2.84388
PRC1 protein regulator of cytokinesis 1 -2.83521
NUP107 nucleoporin 107kDa -2.83406
DHCR7 7-dehydrocholesterol reductase -2.83257
SNRPD2 small nuclear ribonucleoprotein D2 polypeptide 16.5kDa -2.8297
DBF4 DBF4 zinc finger -2.82832
GGA2 golgi-associated, gamma adaptin ear containing, ARF binding protein 2 -2.82593
POLR2H polymerase (RNA) II (DNA directed) polypeptide H -2.8175
SZRD1 SUZ RNA binding domain containing 1 -2.81494
LSM5 LSM5 homolog, U6 small nuclear RNA associated (S. cerevisiae) -2.81433
UBE2C ubiquitin-conjugating enzyme E2C -2.81033
AUNIP aurora kinase A and ninein interacting protein -2.80655
NCLN nicalin -2.80524
CCNE2 cyclin E2 -2.80312
PCNT pericentrin -2.80226
CDCA3 cell division cycle associated 3 -2.7949
GMNN geminin, DNA replication inhibitor -2.79105
CCND3 cyclin D3 -2.78824
HNRNPF heterogeneous nuclear ribonucleoprotein F -2.7873
YJU2 YJU2 splicing factor homolog -2.78565
NUBP2 nucleotide binding protein 2 -2.78314
PWP2 PWP2 periodic tryptophan protein homolog (yeast) -2.78187
SYPL1 synaptophysin-like 1 -2.77899
SLC25A13 solute carrier family 25 (aspartate/glutamate carrier), member 13 -2.77602
VMP1 vacuole membrane protein 1 -2.77403
HIPK3 homeodomain interacting protein kinase 3 -2.76928
ATP5MC3 ATP synthase membrane subunit c locus 3 -2.76807
ALDH1B1 aldehyde dehydrogenase 1 family, member B1 -2.76646
HNRNPR heterogeneous nuclear ribonucleoprotein R -2.76604
CLEC7A C-type lectin domain family 7, member A -2.76463
CHAF1B chromatin assembly factor 1, subunit B (p60) -2.76425
KRT13 keratin 13, type I -2.76379
COX7B cytochrome c oxidase subunit VIIb -2.76213
LCMT2 leucine carboxyl methyltransferase 2 -2.75925
HMGN2 high mobility group nucleosomal binding domain 2 -2.75753
DFFB DNA fragmentation factor, 40kDa, beta polypeptide (caspase-activated DNase) -2.75516
NAGA N-acetylgalactosaminidase, alpha- -2.75384
HOXA4 homeobox A4 -2.75248
DDX23 DEAD (Asp-Glu-Ala-Asp) box polypeptide 23 -2.75112
MSN moesin -2.74953
NAP1L4 nucleosome assembly protein 1-like 4 -2.74574
GPAA1 glycosylphosphatidylinositol anchor attachment 1 -2.74325
BACE2 beta-site APP-cleaving enzyme 2 -2.73489
PSMA3 proteasome (prosome, macropain) subunit, alpha type, 3 -2.73189
THOP1 thimet oligopeptidase 1 -2.7268
OPA3 optic atrophy 3 (autosomal recessive, with chorea and spastic paraplegia) -2.72581
TFDP1 transcription factor Dp-1 -2.7173
SRSF1 serine/arginine-rich splicing factor 1 -2.71657
YKT6 YKT6 v-SNARE homolog (S. cerevisiae) -2.7164
DTL denticleless E3 ubiquitin protein ligase homolog (Drosophila) -2.71568
UMPS uridine monophosphate synthetase -2.715
TOMM22 translocase of outer mitochondrial membrane 22 homolog (yeast) -2.71249
EIF4E eukaryotic translation initiation factor 4E -2.71056
METTL16 methyltransferase like 16 -2.70894
MVD mevalonate (diphospho) decarboxylase -2.70874
KDM1A lysine (K)-specific demethylase 1A -2.70799
SNRPA1 small nuclear ribonucleoprotein polypeptide A' -2.7078
RTL10 retrotransposon Gag like 10 -2.69932
PLK4 polo-like kinase 4 -2.69349
ANP32A acidic (leucine-rich) nuclear phosphoprotein 32 family, member A -2.6771
H2AX H2A.X variant histone -2.67599
SCRIB scribbled planar cell polarity protein -2.67587
ENY2 enhancer of yellow 2 homolog (Drosophila) -2.6747
SOD1 superoxide dismutase 1, soluble -2.67324
HSP90AB1 heat shock protein 90kDa alpha (cytosolic), class B member 1 -2.67022
SEPHS1 selenophosphate synthetase 1 -2.66851
DNM1 dynamin 1 -2.66704
AMDHD2 amidohydrolase domain containing 2 -2.66587
TUBA1C tubulin, alpha 1c -2.65979
KIF22 kinesin family member 22 -2.65891
SLC25A10 solute carrier family 25 (mitochondrial carrier; dicarboxylate transporter), member 10 -2.65833
SHPK sedoheptulokinase -2.65783
EIF4G1 eukaryotic translation initiation factor 4 gamma, 1 -2.65727
CDCA4 cell division cycle associated 4 -2.65598
ESRP2 epithelial splicing regulatory protein 2 -2.65439
MREG melanoregulin -2.65371
LOC124905557 eukaryotic translation initiation factor 1A, X-chromosomal -2.65362
CAPRIN1 cell cycle associated protein 1 -2.65104
GEMIN6 gem (nuclear organelle) associated protein 6 -2.64318
DDX19A DEAD (Asp-Glu-Ala-Asp) box polypeptide 19A -2.64295
VRK1 vaccinia related kinase 1 -2.64279
FGFR3 fibroblast growth factor receptor 3 -2.63768
ICE1 interactor of little elongation complex ELL subunit 1 -2.63463
BRIX1 BRX1, biogenesis of ribosomes -2.63418
APEH acylaminoacyl-peptide hydrolase -2.634
HDAC2 histone deacetylase 2 -2.63234
LARS2 leucyl-tRNA synthetase 2, mitochondrial -2.63078
CKAP2 cytoskeleton associated protein 2 -2.63041
YARS2 tyrosyl-tRNA synthetase 2, mitochondrial -2.62905
PSMB3 proteasome (prosome, macropain) subunit, beta type, 3 -2.62889
TOMM6 translocase of outer mitochondrial membrane 6 homolog (yeast) -2.62423
SLC46A3 solute carrier family 46, member 3 -2.62281
TUBB4B tubulin, beta 4B class IVb -2.62208
ZNF207 zinc finger protein 207 -2.61665
ANAPC15 anaphase promoting complex subunit 15 -2.61435
KIF4A kinesin family member 4A -2.61111
ACLY ATP citrate lyase -2.61092
VDAC3 voltage-dependent anion channel 3 -2.61026
TFAM transcription factor A, mitochondrial -2.60923
HSD17B7 hydroxysteroid (17-beta) dehydrogenase 7 -2.60901
ITGB6 integrin, beta 6 -2.60356
SUMO4 small ubiquitin-like modifier 4 -2.60353
FCER1A Fc fragment of IgE, high affinity I, receptor for; alpha polypeptide -2.5968
GALNT2 polypeptide N-acetylgalactosaminyltransferase 2 -2.59602
VPS26C VPS26 endosomal protein sorting factor C -2.59179
NPLOC4 nuclear protein localization 4 homolog (S. cerevisiae) -2.58717
PRPF6 pre-mRNA processing factor 6 -2.58596
RBMS1 RNA binding motif, single stranded interacting protein 1 -2.5852
CENPX centromere protein X -2.58489
RUSC1 RUN and SH3 domain containing 1 -2.58414
BICD2 bicaudal D homolog 2 (Drosophila) -2.58298
BORCS8 BLOC-1 related complex subunit 8 -2.58148
PRKDC protein kinase, DNA-activated, catalytic polypeptide -2.57884
RHOT2 ras homolog family member T2 -2.57673
SHQ1 SHQ1, H/ACA ribonucleoprotein assembly factor -2.57503
RBL1 retinoblastoma-like 1 -2.57427
FIRRM FIGNL1 interacting regulator of recombination and mitosis -2.57302
PLK1 polo-like kinase 1 -2.57294
ERH enhancer of rudimentary homolog (Drosophila) -2.57173
PRCC papillary renal cell carcinoma (translocation-associated) -2.57087
HMGB2 high mobility group box 2 -2.57006
NUP205 nucleoporin 205kDa -2.56471
TUBA1A tubulin, alpha 1a -2.56328
MVP major vault protein -2.56085
CD47 CD47 molecule -2.55895
MICB MHC class I polypeptide-related sequence B -2.55008
TMCO1 transmembrane and coiled-coil domains 1 -2.54995
ZMYM1 zinc finger, MYM-type 1 -2.54688
RGS2 regulator of G-protein signaling 2 -2.54597
PGM1 phosphoglucomutase 1 -2.5458
NOL11 nucleolar protein 11 -2.54533
PRRG4 proline rich Gla (G-carboxyglutamic acid) 4 (transmembrane) -2.54013
LIN9 lin-9 DREAM MuvB core complex component -2.53878
SPON1 spondin 1, extracellular matrix protein -2.53142
SOCS5 suppressor of cytokine signaling 5 -2.52966
NUDT1 nudix (nucleoside diphosphate linked moiety X)-type motif 1 -2.52889
GRHL2 grainyhead-like 2 (Drosophila) -2.52887
BORA bora, aurora kinase A activator -2.52453
RTF1 Rtf1, Paf1/RNA polymerase II complex component, homolog (S. cerevisiae) -2.52255
XPNPEP3 X-prolyl aminopeptidase 3, mitochondrial -2.51476
TRAPPC2 trafficking protein particle complex 2 -2.51058
SPPL2A signal peptide peptidase like 2A -2.51057
XPO1 exportin 1 -2.51036
CDT1 chromatin licensing and DNA replication factor 1 -2.50921
CPPED1 calcineurin-like phosphoesterase domain containing 1 -2.5065
MTMR12 myotubularin related protein 12 -2.50378
PRKCD protein kinase C, delta -2.50259
RIC8A RIC8 guanine nucleotide exchange factor A -2.50182
G3BP2 GTPase activating protein (SH3 domain) binding protein 2 -2.49824
SCML1 sex comb on midleg-like 1 (Drosophila) -2.4959
ZNF180 zinc finger protein 180 -2.49441
CSTF2 cleavage stimulation factor, 3' pre-RNA, subunit 2, 64kDa -2.49209
NUP153 nucleoporin 153kDa -2.49041
FGFBP1 fibroblast growth factor binding protein 1 -2.48541
E2F1 E2F transcription factor 1 -2.48525
CHEK1 checkpoint kinase 1 -2.47964
ATP6V0E1 ATPase, H+ transporting, lysosomal 9kDa, V0 subunit e1 -2.47467
POLK polymerase (DNA directed) kappa -2.47367
SNRPD3 small nuclear ribonucleoprotein D3 polypeptide 18kDa -2.47272
FKBP15 FK506 binding protein 15, 133kDa -2.47268
TRAP1 TNF receptor-associated protein 1 -2.4692
MRPL44 mitochondrial ribosomal protein L44 -2.46906
PPP1R8 protein phosphatase 1, regulatory subunit 8 -2.4689
PIK3R4 phosphoinositide-3-kinase, regulatory subunit 4 -2.4672
PTBP1 polypyrimidine tract binding protein 1 -2.46638
NCS1 neuronal calcium sensor 1 -2.46457
HNRNPH2 heterogeneous nuclear ribonucleoprotein H2 (H') -2.46359
KRT14 keratin 14, type I -2.46202
LMNB1 lamin B1 -2.4617
INTS9 integrator complex subunit 9 -2.4605
RYK receptor-like tyrosine kinase -2.45959
SNRPB small nuclear ribonucleoprotein polypeptides B and B1 -2.45419
NAT10 N-acetyltransferase 10 (GCN5-related) -2.45409
HNRNPD heterogeneous nuclear ribonucleoprotein D (AU-rich element RNA binding protein 1, 37kDa) -2.45327
FKBP5 FK506 binding protein 5 -2.45281
CIAPIN1 cytokine induced apoptosis inhibitor 1 -2.45263
HDAC3 histone deacetylase 3 -2.45228
TMEM9B TMEM9 domain family, member B -2.45109
GALP galanin-like peptide -2.44852
SUV39H2 suppressor of variegation 3-9 homolog 2 (Drosophila) -2.44711
RFC2 replication factor C (activator 1) 2, 40kDa -2.44704
POLR2C polymerase (RNA) II (DNA directed) polypeptide C, 33kDa -2.44697
FZD4 frizzled class receptor 4 -2.44676
SETMAR SET domain and mariner transposase fusion gene -2.44337
GPD2 glycerol-3-phosphate dehydrogenase 2 (mitochondrial) -2.43975
DEF8 differentially expressed in FDCP 8 homolog (mouse) -2.43547
DOLK dolichol kinase -2.43449
PLEKHJ1 pleckstrin homology domain containing, family J member 1 -2.43023
ZFYVE21 zinc finger, FYVE domain containing 21 -2.42391
ANXA2 annexin A2 -2.42282
ZC3HAV1 zinc finger CCCH-type, antiviral 1 -2.42093
KDM3B lysine (K)-specific demethylase 3B -2.41963
MRPS2 mitochondrial ribosomal protein S2 -2.41946
EHMT2 euchromatic histone-lysine N-methyltransferase 2 -2.41746
HNRNPA3 heterogeneous nuclear ribonucleoprotein A3 -2.4174
RIOX1 ribosomal oxygenase 1 -2.41721
MAP3K6 mitogen-activated protein kinase kinase kinase 6 -2.41616
SNRPC small nuclear ribonucleoprotein polypeptide C -2.41611
H2AZ1 H2A.Z variant histone 1 -2.41562
DCLRE1B DNA cross-link repair 1B -2.41011
SH3GLB2 SH3-domain GRB2-like endophilin B2 -2.40866
LOC128966601 pyruvate dehydrogenase phosphatase regulatory subunit, mitochondrial-like -2.40575
CDCA8 cell division cycle associated 8 -2.40443
COA4 cytochrome c oxidase assembly factor 4 homolog (S. cerevisiae) -2.40363
PRPF19 pre-mRNA processing factor 19 -2.40182
TMEM259 transmembrane protein 259 -2.40065
CTDP1 CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) phosphatase, subunit 1 -2.39997
ASB6 ankyrin repeat and SOCS box containing 6 -2.39915
ZFX zinc finger protein, X-linked -2.39889
TTLL12 tubulin tyrosine ligase-like family member 12 -2.3964
TRMT61B tRNA methyltransferase 61B -2.39638
MYCBP MYC binding protein -2.39506
MRPS34 mitochondrial ribosomal protein S34 -2.39266
MOCS3 molybdenum cofactor synthesis 3 -2.39237
PCLAF PCNA clamp associated factor -2.38765
GLRX5 glutaredoxin 5 -2.38526
TRMT112 tRNA methyltransferase 11-2 homolog (S. cerevisiae) -2.3849
NUP93 nucleoporin 93kDa -2.38461
CALM2 calmodulin 2 (phosphorylase kinase, delta) -2.38289
ECD ecdysoneless homolog (Drosophila) -2.376
MAPK1 mitogen-activated protein kinase 1 -2.37293
GYS1 glycogen synthase 1 (muscle) -2.37008
CYB561D2 cytochrome b561 family, member D2 -2.36953
NFYA nuclear transcription factor Y, alpha -2.36668
SLC1A3 solute carrier family 1 (glial high affinity glutamate transporter), member 3 -2.36114
EED embryonic ectoderm development -2.35905
ZNF273 zinc finger protein 273 -2.35713
METTL3 methyltransferase like 3 -2.35654
TOPORS topoisomerase I binding, arginine/serine-rich, E3 ubiquitin protein ligase -2.35536
RSU1 Ras suppressor protein 1 -2.3552
PGC progastricsin (pepsinogen C) -2.35443
TRIM32 tripartite motif containing 32 -2.35428
EXOSC2 exosome component 2 -2.35304
REEP5 receptor accessory protein 5 -2.35061
RRP1B ribosomal RNA processing 1B -2.34847
CLN3 ceroid-lipofuscinosis, neuronal 3 -2.34837
DLGAP5 discs, large (Drosophila) homolog-associated protein 5 -2.34281
MKI67 marker of proliferation Ki-67 -2.3408
TARDBP TAR DNA binding protein -2.33966
DEAF1 DEAF1 transcription factor -2.33817
RMI1 RecQ mediated genome instability 1 -2.3373
ATAD5 ATPase family, AAA domain containing 5 -2.33399
ELOC elongin C -2.33301
RPP38 ribonuclease P/MRP 38kDa subunit -2.33268
PAICS phosphoribosylaminoimidazole carboxylase, phosphoribosylaminoimidazole succinocarboxamide synthetase -2.33267
CENPN centromere protein N -2.33248
EXOSC4 exosome component 4 -2.33177
UFD1 ubiquitin recognition factor in ER associated degradation 1 -2.33038
FAM32A family with sequence similarity 32, member A -2.32782
DAG1 dystroglycan 1 (dystrophin-associated glycoprotein 1) -2.32536
RBBP4 retinoblastoma binding protein 4 -2.32395
CCN3 cellular communication network factor 3 -2.32301
PXMP4 peroxisomal membrane protein 4, 24kDa -2.32222
PBK PDZ binding kinase -2.31977
SLC10A3 solute carrier family 10, member 3 -2.31945
CBX1 chromobox homolog 1 -2.31628
CDC23 cell division cycle 23 -2.31385
LRRC40 leucine rich repeat containing 40 -2.31008
CS citrate synthase -2.30917
UBE2L3 ubiquitin-conjugating enzyme E2L 3 -2.30784
TGIF2 TGFB-induced factor homeobox 2 -2.3071
HSPA14 heat shock 70kDa protein 14 -2.30665
WDR6 WD repeat domain 6 -2.30074
PAQR4 progestin and adipoQ receptor family member IV -2.29623
PSME3 proteasome (prosome, macropain) activator subunit 3 (PA28 gamma; Ki) -2.29614
ATP5MC1 ATP synthase membrane subunit c locus 1 -2.29514
ALG8 ALG8, alpha-1,3-glucosyltransferase -2.29448
TSPAN3 tetraspanin 3 -2.29074
HERC2 HECT and RLD domain containing E3 ubiquitin protein ligase 2 -2.2886
CDK4 cyclin-dependent kinase 4 -2.28852
TCOF1 Treacher Collins-Franceschetti syndrome 1 -2.28783
PMPCA peptidase (mitochondrial processing) alpha -2.2858
ZNF318 zinc finger protein 318 -2.28504
PDCL phosducin-like -2.28492
BCAP31 B-cell receptor-associated protein 31 -2.27769
CD320 CD320 molecule -2.27481
SRRM1 serine/arginine repetitive matrix 1 -2.27031
SEM1 SEM1 26S proteasome subunit -2.26496
MTAP methylthioadenosine phosphorylase -2.26347
ARRB1 arrestin, beta 1 -2.26325
PLEKHA2 pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 2 -2.25907
SERPINB3 serpin peptidase inhibitor, clade B (ovalbumin), member 3 -2.25318
IREB2 iron-responsive element binding protein 2 -2.25078
BCL7C B-cell CLL/lymphoma 7C -2.24654
ZNF512B zinc finger protein 512B -2.24631
CD207 CD207 molecule, langerin -2.24602
GPR88 G protein-coupled receptor 88 -2.24595
CFAP20 cilia and flagella associated protein 20 -2.24567
COLGALT1 collagen beta(1-O)galactosyltransferase 1 -2.24545
MPZL2 myelin protein zero-like 2 -2.24429
TMEM115 transmembrane protein 115 -2.24332
MDH1 malate dehydrogenase 1, NAD (soluble) -2.24265
DPYD dihydropyrimidine dehydrogenase -2.24262
HADH hydroxyacyl-CoA dehydrogenase -2.241
PPP4R3B protein phosphatase 4 regulatory subunit 3B -2.23979
DNAJB1 DnaJ (Hsp40) homolog, subfamily B, member 1 -2.23922
ABT1 activator of basal transcription 1 -2.23867
AREL1 apoptosis resistant E3 ubiquitin protein ligase 1 -2.23795
ZNF85 zinc finger protein 85 -2.23745
MOB1A MOB kinase activator 1A -2.23736
ZNF195 zinc finger protein 195 -2.2367
DDX11 DEAD/H (Asp-Glu-Ala-Asp/His) box helicase 11 -2.23455
RFWD3 ring finger and WD repeat domain 3 -2.23246
RAB27A RAB27A, member RAS oncogene family -2.22905
BUB3 BUB3 mitotic checkpoint protein -2.22881
KPNA2 karyopherin alpha 2 (RAG cohort 1, importin alpha 1) -2.22682
HNRNPM heterogeneous nuclear ribonucleoprotein M -2.22603
AGO1 argonaute RISC catalytic component 1 -2.22425
FOXRED2 FAD-dependent oxidoreductase domain containing 2 -2.22363
PRR5 proline rich 5 (renal) -2.21544
KIF23 kinesin family member 23 -2.2141
RBM38 RNA binding motif protein 38 -2.21279
CALM3 calmodulin 3 (phosphorylase kinase, delta) -2.20665
SAMHD1 SAM domain and HD domain 1 -2.20499
WRAP53 WD repeat containing, antisense to TP53 -2.20467
NMU neuromedin U -2.20455
QPRT quinolinate phosphoribosyltransferase -2.20349
RAD54L RAD54-like (S. cerevisiae) -2.20216
SNX10 sorting nexin 10 -2.19499
RPL23 ribosomal protein L23 -2.19475
BRCC3 BRCA1/BRCA2-containing complex, subunit 3 -2.19417
DHX29 DEAH (Asp-Glu-Ala-His) box polypeptide 29 -2.19351
TMSB10 thymosin beta 10 -2.1933
CRY2 cryptochrome circadian clock 2 -2.19307
SMNDC1 survival motor neuron domain containing 1 -2.19249
CBFB core-binding factor, beta subunit -2.19195
RPS6KB1 ribosomal protein S6 kinase, 70kDa, polypeptide 1 -2.19144
TRIM52 tripartite motif containing 52 -2.19019
MAZ MYC-associated zinc finger protein (purine-binding transcription factor) -2.18926
CKS2 CDC28 protein kinase regulatory subunit 2 -2.18878
TBC1D10C TBC1 domain family, member 10C -2.1887
MARCHF1 membrane associated ring-CH-type finger 1 -2.18839
WDHD1 WD repeat and HMG-box DNA binding protein 1 -2.18768
ZNF675 zinc finger protein 675 -2.18556
PAXIP1 PAX interacting (with transcription-activation domain) protein 1 -2.18432
FANCI Fanconi anemia, complementation group I -2.18284
POMK protein-O-mannose kinase -2.18213
SNRPF small nuclear ribonucleoprotein polypeptide F -2.18097
SERF1A small EDRK-rich factor 1A (telomeric) -2.18006
COQ7 coenzyme Q7 homolog, ubiquinone (yeast) -2.17868
SCML2 sex comb on midleg-like 2 (Drosophila) -2.1785
MRPL20 mitochondrial ribosomal protein L20 -2.17783
GAR1 GAR1 ribonucleoprotein -2.17698
AMACR alpha-methylacyl-CoA racemase -2.17589
NDUFAF7 NADH dehydrogenase (ubiquinone) complex I, assembly factor 7 -2.17291
MRM2 mitochondrial rRNA methyltransferase 2 -2.17183
TTI1 TELO2 interacting protein 1 -2.17137
FADD Fas (TNFRSF6)-associated via death domain -2.16729
EPM2AIP1 EPM2A (laforin) interacting protein 1 -2.16629
LOC102724594 splicing factor U2AF 35 kDa subunit -2.16599
CDKAL1 CDK5 regulatory subunit associated protein 1-like 1 -2.16594
EPN3 epsin 3 -2.16573
TRMT5 tRNA methyltransferase 5 -2.16558
HYAL2 hyaluronoglucosaminidase 2 -2.16485
MTHFD1 methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1, methenyltetrahydrofolate cyclohydrolase, formyltetrahydrofolate synthetase -2.16323
LOC124907090 ankyrin repeat domain-containing protein SOWAHC-like -2.16267
ATP5MF ATP synthase membrane subunit f -2.15998
SLC25A1 solute carrier family 25 (mitochondrial carrier; citrate transporter), member 1 -2.15906
EGLN1 egl-9 family hypoxia-inducible factor 1 -2.15901
TIMM13 translocase of inner mitochondrial membrane 13 homolog (yeast) -2.15727
HACD2 3-hydroxyacyl-CoA dehydratase 2 -2.15684
USP22 ubiquitin specific peptidase 22 -2.15519
SYTL2 synaptotagmin-like 2 -2.15461
P2RY6 pyrimidinergic receptor P2Y, G-protein coupled, 6 -2.15335
PNPO pyridoxamine 5'-phosphate oxidase -2.15207
VANGL1 VANGL planar cell polarity protein 1 -2.1516
NDNF neuron-derived neurotrophic factor -2.15147
PRMT2 protein arginine methyltransferase 2 -2.15122
NDUFS6 NADH dehydrogenase (ubiquinone) Fe-S protein 6, 13kDa (NADH-coenzyme Q reductase) -2.15054
DARS2 aspartyl-tRNA synthetase 2, mitochondrial -2.14786
UCKL1 uridine-cytidine kinase 1-like 1 -2.14672
ARL2BP ADP-ribosylation factor-like 2 binding protein -2.14583
CBX3 chromobox homolog 3 -2.14581
CPSF6 cleavage and polyadenylation specific factor 6, 68kDa -2.14555
SCGB1D1 secretoglobin, family 1D, member 1 -2.14328
PPIH peptidylprolyl isomerase H (cyclophilin H) -2.14222
PIMREG PICALM interacting mitotic regulator -2.14059
NUDT15 nudix (nucleoside diphosphate linked moiety X)-type motif 15 -2.14042
PTPRJ protein tyrosine phosphatase, receptor type, J -2.14024
PARPBP PARP1 binding protein -2.13928
TIMM23 translocase of inner mitochondrial membrane 23 homolog (yeast) -2.13911
TMEM164 transmembrane protein 164 -2.13839
ENG endoglin -2.1382
HSBP1 heat shock factor binding protein 1 -2.13783
TPX2 TPX2, microtubule-associated -2.13185
DERL1 derlin 1 -2.13093
RABIF RAB interacting factor -2.12986
TMEM106C transmembrane protein 106C -2.12871
SINHCAF SIN3-HDAC complex associated factor -2.1281
PDSS1 prenyl (decaprenyl) diphosphate synthase, subunit 1 -2.12687
PTTG1 pituitary tumor-transforming 1 -2.12624
FMR1 fragile X mental retardation 1 -2.12561
PPM1G protein phosphatase, Mg2+/Mn2+ dependent, 1G -2.12483
RRAGA Ras-related GTP binding A -2.12381
CD46 CD46 molecule, complement regulatory protein -2.12263
DUOX1 dual oxidase 1 -2.12184
MRPL49 mitochondrial ribosomal protein L49 -2.1214
DNA2 DNA replication helicase/nuclease 2 -2.12107
TFCP2 transcription factor CP2 -2.12101
SNCG synuclein, gamma (breast cancer-specific protein 1) -2.12088
TGFBR1 transforming growth factor, beta receptor 1 -2.1199
EMP2 epithelial membrane protein 2 -2.11946
FANCA Fanconi anemia, complementation group A -2.11905
NME4 NME/NM23 nucleoside diphosphate kinase 4 -2.11881
SELENOT selenoprotein T -2.11808
PIN4 peptidylprolyl cis/trans isomerase, NIMA-interacting 4 -2.1173
NOP10 NOP10 ribonucleoprotein -2.11524
API5 apoptosis inhibitor 5 -2.11449
PDHA1 pyruvate dehydrogenase (lipoamide) alpha 1 -2.11409
CSTF1 cleavage stimulation factor, 3' pre-RNA, subunit 1, 50kDa -2.11363
NME1 NME/NM23 nucleoside diphosphate kinase 1 -2.11305
NELFB negative elongation factor complex member B -2.11276
FDFT1 farnesyl-diphosphate farnesyltransferase 1 -2.11252
DAND5 DAN domain family member 5, BMP antagonist -2.10967
SLC7A6 solute carrier family 7 (amino acid transporter light chain, y+L system), member 6 -2.10883
BPNT2 3'(2'), 5'-bisphosphate nucleotidase 2 -2.10834
ICMT isoprenylcysteine carboxyl methyltransferase -2.10809
MEN1 multiple endocrine neoplasia I -2.10611
CBR1 carbonyl reductase 1 -2.10552
ZNF174 zinc finger protein 174 -2.10539
POLD1 polymerase (DNA directed), delta 1, catalytic subunit -2.10512
SMIM8 small integral membrane protein 8 -2.10378
XRCC6 X-ray repair complementing defective repair in Chinese hamster cells 6 -2.10293
TMOD3 tropomodulin 3 (ubiquitous) -2.10255
HAUS7 HAUS augmin-like complex, subunit 7 -2.10242
KCNA3 potassium channel, voltage gated shaker related subfamily A, member 3 -2.10222
SPINK5 serine peptidase inhibitor, Kazal type 5 -2.10187
SDHA succinate dehydrogenase complex, subunit A, flavoprotein (Fp) -2.10133
UBIAD1 UbiA prenyltransferase domain containing 1 -2.09906
FGD2 FYVE, RhoGEF and PH domain containing 2 -2.09568
DHX35 DEAH (Asp-Glu-Ala-His) box polypeptide 35 -2.09525
CCNB2 cyclin B2 -2.09395
EXOSC9 exosome component 9 -2.09337
LGR4 leucine-rich repeat containing G protein-coupled receptor 4 -2.08994
GNPDA1 glucosamine-6-phosphate deaminase 1 -2.08928
RAB5C RAB5C, member RAS oncogene family -2.0881
NDC1 NDC1 transmembrane nucleoporin -2.08638
LAMTOR5 late endosomal/lysosomal adaptor, MAPK and MTOR activator 5 -2.08528
MYC v-myc avian myelocytomatosis viral oncogene homolog -2.08403
HS3ST1 heparan sulfate (glucosamine) 3-O-sulfotransferase 1 -2.08358
ERG28 ergosterol biosynthesis 28 homolog -2.08228
KRT15 keratin 15, type I -2.08192
TMEM33 transmembrane protein 33 -2.08138
ATP5F1C ATP synthase F1 subunit gamma -2.08087
SNRPG small nuclear ribonucleoprotein polypeptide G -2.07919
ADISSP adipose secreted signaling protein -2.07849
FBXO5 F-box protein 5 -2.07696
GAPVD1 GTPase activating protein and VPS9 domains 1 -2.07677
GET3 guided entry of tail-anchored proteins factor 3, ATPase -2.07631
NUP155 nucleoporin 155kDa -2.07158
MRTO4 mRNA turnover 4 homolog (S. cerevisiae) -2.06991
EPHX3 epoxide hydrolase 3 -2.06773
HELLS helicase, lymphoid-specific -2.06683
GALNT11 polypeptide N-acetylgalactosaminyltransferase 11 -2.06605
RACGAP1 Rac GTPase activating protein 1 -2.06597
NAAA N-acylethanolamine acid amidase -2.06512
NAA10 N(alpha)-acetyltransferase 10, NatA catalytic subunit -2.0641
ZNF107 zinc finger protein 107 -2.06277
HMGB3 high mobility group box 3 -2.06137
TAX1BP3 Tax1 (human T-cell leukemia virus type I) binding protein 3 -2.06045
DDB1 damage-specific DNA binding protein 1, 127kDa -2.058
DNTTIP2 deoxynucleotidyltransferase, terminal, interacting protein 2 -2.05776
RPS6KA4 ribosomal protein S6 kinase, 90kDa, polypeptide 4 -2.05662
AIFM1 apoptosis-inducing factor, mitochondrion-associated, 1 -2.05598
CLIC2 chloride intracellular channel 2 -2.05374
TMT1A thiol methyltransferase 1A -2.05138
SUGCT succinyl-CoA:glutarate-CoA transferase -2.05106
KLK8 kallikrein-related peptidase 8 -2.05078
SLC18A2 solute carrier family 18 (vesicular monoamine transporter), member 2 -2.05026
SFT2D2 SFT2 domain containing 2 -2.05023
DCAF16 DDB1 and CUL4 associated factor 16 -2.04941
CSE1L CSE1 chromosome segregation 1-like (yeast) -2.0492
MAT2B methionine adenosyltransferase II, beta -2.0485
HLF hepatic leukemia factor -2.04848
EXO1 exonuclease 1 -2.0475
CHORDC1 cysteine and histidine-rich domain (CHORD) containing 1 -2.04718
PDHB pyruvate dehydrogenase (lipoamide) beta -2.04627
POLR1F RNA polymerase I subunit F -2.0457
FRAT2 frequently rearranged in advanced T-cell lymphomas 2 -2.04482
SCD stearoyl-CoA desaturase (delta-9-desaturase) -2.04307
HIRIP3 HIRA interacting protein 3 -2.04143
VCP valosin containing protein -2.04119
RABL6 RAB, member RAS oncogene family-like 6 -2.0402
YEATS4 YEATS domain containing 4 -2.03795
B4GALT5 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 -2.0378
ZCCHC14 zinc finger, CCHC domain containing 14 -2.0373
SHMT1 serine hydroxymethyltransferase 1 (soluble) -2.03635
NUDT19 nudix (nucleoside diphosphate linked moiety X)-type motif 19 -2.03554
NDUFB3 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 3, 12kDa -2.03508
NONO non-POU domain containing, octamer-binding -2.03504
SLC8B1 solute carrier family 8 (sodium/lithium/calcium exchanger), member B1 -2.03022
METTL2A methyltransferase like 2A -2.02959
RACK1 receptor for activated C kinase 1 -2.0295
MED17 mediator complex subunit 17 -2.0291
UGT2A1 UDP glucuronosyltransferase 2 family, polypeptide A1, complex locus -2.02732
MCOLN1 mucolipin 1 -2.02729
THAP11 THAP domain containing 11 -2.02667
IARS2 isoleucyl-tRNA synthetase 2, mitochondrial -2.02542
PCYT1A phosphate cytidylyltransferase 1, choline, alpha -2.02276
MS4A4A membrane-spanning 4-domains, subfamily A, member 4A -2.02263
ANKRD10 ankyrin repeat domain 10 -2.02201
CYB5R3 cytochrome b5 reductase 3 -2.02125
PRR5L proline rich 5 like -2.01891
CSNK1G2 casein kinase 1, gamma 2 -2.01705
MED21 mediator complex subunit 21 -2.01671
WASHC5 WASH complex subunit 5 -2.01449
LPCAT1 lysophosphatidylcholine acyltransferase 1 -2.0138
RNF125 ring finger protein 125, E3 ubiquitin protein ligase -2.01236
GRSF1 G-rich RNA sequence binding factor 1 -2.00919
PHTF2 putative homeodomain transcription factor 2 -2.00737
HAUS6 HAUS augmin-like complex, subunit 6 -2.00664
PSMB2 proteasome (prosome, macropain) subunit, beta type, 2 -2.00456
LBR lamin B receptor -2.00131