CRCGN017_MCF10A.TP53.M_24H:H10 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description tetracycline 101.47 um perturbation at 24 h in MCF10A.TP53.M (Carcinogenome)
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Genes

860 genes differentially expressed following the CRCGN017_MCF10A.TP53.M_24H:H10 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
GFPT1 glutamine--fructose-6-phosphate transaminase 1 9.301
PCK2 phosphoenolpyruvate carboxykinase 2 (mitochondrial) 8.65223
MTHFD2 methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase 8.59155
CXCL2 chemokine (C-X-C motif) ligand 2 8.11777
HMOX1 heme oxygenase 1 7.90086
NUCB2 nucleobindin 2 7.27204
PYCR1 pyrroline-5-carboxylate reductase 1 7.26427
ATF4 activating transcription factor 4 7.05576
AARS1 alanyl-tRNA synthetase 1 7.03175
CHAC1 ChaC glutathione-specific gamma-glutamylcyclotransferase 1 6.58296
GARS1 glycyl-tRNA synthetase 1 6.42808
SLC7A11 solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 6.20861
TRIB3 tribbles pseudokinase 3 6.19374
GRB10 growth factor receptor-bound protein 10 6.1608
LOC128125814 uncharacterized LOC128125814 6.11603
TXNRD1 thioredoxin reductase 1 6.10682
ARHGEF2 Rho/Rac guanine nucleotide exchange factor (GEF) 2 5.95529
SLC35B1 solute carrier family 35, member B1 5.80836
GLRX glutaredoxin (thioltransferase) 5.72019
SLC1A4 solute carrier family 1 (glutamate/neutral amino acid transporter), member 4 5.71691
P4HA2 prolyl 4-hydroxylase, alpha polypeptide II 5.62026
CTSL cathepsin L 5.55693
ASNS asparagine synthetase (glutamine-hydrolyzing) 5.54659
CEBPG CCAAT/enhancer binding protein (C/EBP), gamma 5.51747
CARS1 cysteinyl-tRNA synthetase 1 5.50154
CHIC2 cysteine-rich hydrophobic domain 2 5.4168
SARS1 seryl-tRNA synthetase 1 5.41027
HYOU1 hypoxia up-regulated 1 5.40681
VSIG2 V-set and immunoglobulin domain containing 2 5.39327
UGDH UDP-glucose 6-dehydrogenase 5.21886
CCNA1 cyclin A1 5.20766
ECH1 enoyl CoA hydratase 1, peroxisomal 5.12704
DDX10 DEAD (Asp-Glu-Ala-Asp) box polypeptide 10 5.09006
WIF1 WNT inhibitory factor 1 5.03753
PHGDH phosphoglycerate dehydrogenase 5.02785
IL1B interleukin 1, beta 5.01048
POLD4 polymerase (DNA-directed), delta 4, accessory subunit 4.97923
PSAT1 phosphoserine aminotransferase 1 4.95575
XPOT exportin, tRNA 4.81854
FYN FYN proto-oncogene, Src family tyrosine kinase 4.79506
TES testin LIM domain protein 4.75567
EIF4EBP1 eukaryotic translation initiation factor 4E binding protein 1 4.70773
CXCL3 chemokine (C-X-C motif) ligand 3 4.66512
SHMT2 serine hydroxymethyltransferase 2 (mitochondrial) 4.63211
DYRK3 dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3 4.61225
SLC3A2 solute carrier family 3 (amino acid transporter heavy chain), member 2 4.60047
IFRD1 interferon-related developmental regulator 1 4.45992
GMPPA GDP-mannose pyrophosphorylase A 4.4128
YARS1 tyrosyl-tRNA synthetase 1 4.30421
DNAJB9 DnaJ (Hsp40) homolog, subfamily B, member 9 4.27684
HERPUD1 homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 4.26059
TRIB1 tribbles pseudokinase 1 4.19264
DECR1 2,4-dienoyl CoA reductase 1, mitochondrial 4.06306
TMEM39A transmembrane protein 39A 4.05292
HSPA5 heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) 4.03657
UFM1 ubiquitin-fold modifier 1 4.02937
MANF mesencephalic astrocyte-derived neurotrophic factor 3.93204
SIL1 SIL1 nucleotide exchange factor 3.92904
KLHL21 kelch-like family member 21 3.9163
IBTK inhibitor of Bruton agammaglobulinemia tyrosine kinase 3.90671
ARMCX3 armadillo repeat containing, X-linked 3 3.89432
LOC102724560 cystathionine beta-synthase 3.86278
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) 3.80733
NARS1 asparaginyl-tRNA synthetase 1 3.77044
MAP1LC3B microtubule-associated protein 1 light chain 3 beta 3.75644
SNAP25 synaptosomal-associated protein, 25kDa 3.7155
TARS1 threonyl-tRNA synthetase 1 3.68854
EPRS1 glutamyl-prolyl-tRNA synthetase 1 3.66138
LARP6 La ribonucleoprotein domain family, member 6 3.65967
RELB v-rel avian reticuloendotheliosis viral oncogene homolog B 3.63997
GTPBP2 GTP binding protein 2 3.6376
FICD FIC domain containing 3.62988
SQSTM1 sequestosome 1 3.6188
IER3 immediate early response 3 3.61822
WFS1 Wolfram syndrome 1 (wolframin) 3.61241
CHMP4B charged multivesicular body protein 4B 3.61046
TNFRSF12A tumor necrosis factor receptor superfamily, member 12A 3.58679
LYPLA1-TCEA1 LYPLA1-TCEA1 readthrough 3.5417
P3H1 prolyl 3-hydroxylase 1 3.53529
CDPF1 cysteine-rich, DPF motif domain containing 1 3.49593
MAFG v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog G 3.49072
GOLT1A golgi transport 1A 3.48241
EDEM1 ER degradation enhancer, mannosidase alpha-like 1 3.44173
SYT1 synaptotagmin I 3.43343
WIPI1 WD repeat domain, phosphoinositide interacting 1 3.41957
MARS1 methionyl-tRNA synthetase 1 3.41833
EGR1 early growth response 1 3.4176
WARS1 tryptophanyl-tRNA synthetase 1 3.39011
ATF3 activating transcription factor 3 3.38489
STC2 stanniocalcin 2 3.37232
IL1A interleukin 1, alpha 3.35498
SLC1A5 solute carrier family 1 (neutral amino acid transporter), member 5 3.35214
MYDGF myeloid-derived growth factor 3.34139
ANKRD11 ankyrin repeat domain 11 3.34053
HSPA13 heat shock protein 70kDa family, member 13 3.33768
HBEGF heparin-binding EGF-like growth factor 3.33652
SLC67A1 solute carrier family 67 member 1 3.32959
ACVR1 activin A receptor, type I 3.3251
STT3A STT3A, subunit of the oligosaccharyltransferase complex (catalytic) 3.31816
HMGCL 3-hydroxymethyl-3-methylglutaryl-CoA lyase 3.29771
CALU calumenin 3.29363
MAP1B microtubule-associated protein 1B 3.28983
PRAF2 PRA1 domain family, member 2 3.28069
EGR3 early growth response 3 3.27152
TERF2IP telomeric repeat binding factor 2, interacting protein 3.2658
NDEL1 nudE neurodevelopment protein 1-like 1 3.25543
SCFD1 sec1 family domain containing 1 3.24512
NLRP4 NLR family, pyrin domain containing 4 3.24402
SYNGAP1 synaptic Ras GTPase activating protein 1 3.19615
HAX1 HCLS1 associated protein X-1 3.17895
CSGALNACT2 chondroitin sulfate N-acetylgalactosaminyltransferase 2 3.15193
MBD1 methyl-CpG binding domain protein 1 3.14521
OPLAH 5-oxoprolinase (ATP-hydrolysing) 3.13819
SERPINB8 serpin peptidase inhibitor, clade B (ovalbumin), member 8 3.13652
RBP4 retinol binding protein 4, plasma 3.12465
SEC61B Sec61 beta subunit 3.11863
PLAUR plasminogen activator, urokinase receptor 3.11777
HSP90B1 heat shock protein 90kDa beta (Grp94), member 1 3.10759
NIT1 nitrilase 1 3.09166
SEC63 SEC63 homolog (S. cerevisiae) 3.06069
STAMBP STAM binding protein 3.04881
G0S2 G0/G1 switch 2 3.04615
PGM3 phosphoglucomutase 3 3.04247
PKIG protein kinase (cAMP-dependent, catalytic) inhibitor gamma 3.02648
SUCO SUN domain containing ossification factor 2.98978
FHL2 four and a half LIM domains 2 2.98647
RPN2 ribophorin II 2.98451
AMPH amphiphysin 2.98088
CSRNP2 cysteine-serine-rich nuclear protein 2 2.97395
KDM4A lysine (K)-specific demethylase 4A 2.97323
TXNDC15 thioredoxin domain containing 15 2.9423
PFDN2 prefoldin subunit 2 2.90341
PMAIP1 phorbol-12-myristate-13-acetate-induced protein 1 2.89749
MOSPD2 motile sperm domain containing 2 2.89559
CCPG1 cell cycle progression 1 2.88764
SLC6A9 solute carrier family 6 (neurotransmitter transporter, glycine), member 9 2.8806
ODR4 odr-4 GPCR localization factor homolog 2.87751
TTC17 tetratricopeptide repeat domain 17 2.86926
KCMF1 potassium channel modulatory factor 1 2.86031
NFE2L1 nuclear factor, erythroid 2-like 1 2.8362
DNAJC1 DnaJ (Hsp40) homolog, subfamily C, member 1 2.82784
AP1G1 adaptor-related protein complex 1, gamma 1 subunit 2.82517
LIF leukemia inhibitory factor 2.82033
P4HB prolyl 4-hydroxylase, beta polypeptide 2.81782
IARS1 isoleucyl-tRNA synthetase 1 2.81744
INKA2 inka box actin regulator 2 2.8046
PDGFA platelet-derived growth factor alpha polypeptide 2.80253
CCS copper chaperone for superoxide dismutase 2.79555
SLC75A1 solute carrier family 75 member 1 2.79374
DNAJC3 DnaJ (Hsp40) homolog, subfamily C, member 3 2.79075
SLC33A1 solute carrier family 33 (acetyl-CoA transporter), member 1 2.77789
WHR1 winged helix repair factor 1 2.77388
RALA v-ral simian leukemia viral oncogene homolog A (ras related) 2.7709
SLC50A1 solute carrier family 50 (sugar efflux transporter), member 1 2.77079
DNAJC10 DnaJ (Hsp40) homolog, subfamily C, member 10 2.75728
GCC1 GRIP and coiled-coil domain containing 1 2.75629
GOLGA3 golgin A3 2.74871
CTBS chitobiase, di-N-acetyl- 2.74569
PPIB peptidylprolyl isomerase B (cyclophilin B) 2.74022
MRPS16 mitochondrial ribosomal protein S16 2.71392
CAMTA2 calmodulin binding transcription activator 2 2.71389
MED8 mediator complex subunit 8 2.7066
ZFAND1 zinc finger, AN1-type domain 1 2.70622
NPY5R neuropeptide Y receptor Y5 2.70077
RPS6KA2 ribosomal protein S6 kinase, 90kDa, polypeptide 2 2.69605
CIRBP cold inducible RNA binding protein 2.69357
NUPR1 nuclear protein, transcriptional regulator, 1 2.68853
DERL2 derlin 2 2.68303
LOC128125822 uncharacterized LOC128125822 2.6748
CYP27B1 cytochrome P450, family 27, subfamily B, polypeptide 1 2.66834
AZIN2 antizyme inhibitor 2 2.66832
ZNF281 zinc finger protein 281 2.65857
PCSK1 proprotein convertase subtilisin/kexin type 1 2.65682
VEGFA vascular endothelial growth factor A 2.65638
GMFG glia maturation factor, gamma 2.65199
DNAJB2 DnaJ (Hsp40) homolog, subfamily B, member 2 2.64601
TESC tescalcin 2.64298
CASK calcium/calmodulin-dependent serine protein kinase (MAGUK family) 2.63699
SSR3 signal sequence receptor, gamma (translocon-associated protein gamma) 2.63236
HDLBP high density lipoprotein binding protein 2.63164
EIF2B4 eukaryotic translation initiation factor 2B, subunit 4 delta, 67kDa 2.62955
AGA aspartylglucosaminidase 2.62583
FOSL1 FOS-like antigen 1 2.62529
ATF6 activating transcription factor 6 2.62427
SLC35F6 solute carrier family 35, member F6 2.62086
ARMCX2 armadillo repeat containing, X-linked 2 2.61795
SLC38A2 solute carrier family 38, member 2 2.61625
SEZ6L2 seizure related 6 homolog (mouse)-like 2 2.61443
UNC5B unc-5 homolog B (C. elegans) 2.61033
RTCA RNA 3'-terminal phosphate cyclase 2.60513
DXO decapping exoribonuclease 2.60348
METTL22 methyltransferase like 22 2.60345
RRAGC Ras-related GTP binding C 2.60094
YIF1A Yip1 interacting factor homolog A (S. cerevisiae) 2.60016
GID4 GID complex subunit 4 2.59543
APLP1 amyloid beta (A4) precursor-like protein 1 2.59517
PDIA4 protein disulfide isomerase family A, member 4 2.59099
METTL25B methyltransferase like 25B 2.5908
CHGB chromogranin B 2.58826
KCTD5 potassium channel tetramerization domain containing 5 2.58497
SCCPDH saccharopine dehydrogenase (putative) 2.58346
ZZZ3 zinc finger, ZZ-type containing 3 2.57543
GALNS galactosamine (N-acetyl)-6-sulfatase 2.56772
INHBE inhibin, beta E 2.56475
LRP10 low density lipoprotein receptor-related protein 10 2.56347
PAMR1 peptidase domain containing associated with muscle regeneration 1 2.56205
PYGB phosphorylase, glycogen; brain 2.55827
PIEZO2 piezo-type mechanosensitive ion channel component 2 2.55239
VEGFC vascular endothelial growth factor C 2.55198
SEC61A1 Sec61 alpha 1 subunit (S. cerevisiae) 2.55053
GORASP2 golgi reassembly stacking protein 2, 55kDa 2.54759
ZCCHC8 zinc finger, CCHC domain containing 8 2.54676
GADD45A growth arrest and DNA-damage-inducible, alpha 2.54548
UGGT1 UDP-glucose glycoprotein glucosyltransferase 1 2.54465
PPCS phosphopantothenoylcysteine synthetase 2.54304
UAP1 UDP-N-acetylglucosamine pyrophosphorylase 1 2.54032
CDK2AP2 cyclin-dependent kinase 2 associated protein 2 2.53046
BEST1 bestrophin 1 2.52607
RAB3GAP1 RAB3 GTPase activating protein subunit 1 (catalytic) 2.52561
SLC30A1 solute carrier family 30 (zinc transporter), member 1 2.52394
CCL22 chemokine (C-C motif) ligand 22 2.5221
RPN1 ribophorin I 2.51411
TM9SF2 transmembrane 9 superfamily member 2 2.51314
PAPPA2 pappalysin 2 2.51128
TRIM2 tripartite motif containing 2 2.50683
KDM6B lysine (K)-specific demethylase 6B 2.50559
TMEM87A transmembrane protein 87A 2.50083
USO1 USO1 vesicle transport factor 2.49905
CREB3L2 cAMP responsive element binding protein 3-like 2 2.49812
NGRN neugrin, neurite outgrowth associated 2.49509
NMNAT2 nicotinamide nucleotide adenylyltransferase 2 2.49477
TAGLN3 transgelin 3 2.49279
CCT6B chaperonin containing TCP1, subunit 6B (zeta 2) 2.49254
ATG13 autophagy related 13 2.48912
OARD1 O-acyl-ADP-ribose deacylase 1 2.48715
BDKRB2 bradykinin receptor B2 2.48665
UFL1 UFM1-specific ligase 1 2.48551
IFI6 interferon, alpha-inducible protein 6 2.47353
SUPT3H suppressor of Ty 3 homolog (S. cerevisiae) 2.47062
SERP1 stress-associated endoplasmic reticulum protein 1 2.46983
NRBF2 nuclear receptor binding factor 2 2.4685
FBXL12 F-box and leucine-rich repeat protein 12 2.46255
GDF5 growth differentiation factor 5 2.46197
NOS1AP nitric oxide synthase 1 (neuronal) adaptor protein 2.46168
DAD1 defender against cell death 1 2.45806
ATP2B1 ATPase, Ca++ transporting, plasma membrane 1 2.45702
SLC35A1 solute carrier family 35 (CMP-sialic acid transporter), member A1 2.45452
PDIA6 protein disulfide isomerase family A, member 6 2.4528
PGAP6 post-GPI attachment to proteins 6 2.45092
ARF4 ADP-ribosylation factor 4 2.45035
RUNDC3A RUN domain containing 3A 2.45035
IGF2R insulin-like growth factor 2 receptor 2.4468
ARMCX6 armadillo repeat containing, X-linked 6 2.44508
PRKRA protein kinase, interferon-inducible double stranded RNA dependent activator 2.4381
KCTD15 potassium channel tetramerization domain containing 15 2.43289
EMC7 ER membrane protein complex subunit 7 2.4254
SEC24D SEC24 family member D 2.42336
GALE UDP-galactose-4-epimerase 2.42267
GNG5 guanine nucleotide binding protein (G protein), gamma 5 2.41912
SLC31A1 solute carrier family 31 (copper transporter), member 1 2.41693
ALAS1 5'-aminolevulinate synthase 1 2.41465
ALOXE3 arachidonate lipoxygenase 3 2.41419
CD55 CD55 molecule, decay accelerating factor for complement (Cromer blood group) 2.4115
PIGV phosphatidylinositol glycan anchor biosynthesis, class V 2.41135
VPS11 vacuolar protein sorting 11 homolog (S. cerevisiae) 2.40954
SLC35G2 solute carrier family 35, member G2 2.40096
BNIP3L BCL2/adenovirus E1B 19kDa interacting protein 3-like 2.39718
MYH9 myosin, heavy chain 9, non-muscle 2.39703
CRELD2 cysteine-rich with EGF-like domains 2 2.39661
GRIN2A glutamate receptor, ionotropic, N-methyl D-aspartate 2A 2.39652
ARFGAP3 ADP-ribosylation factor GTPase activating protein 3 2.39099
SLC39A14 solute carrier family 39 (zinc transporter), member 14 2.38077
GCLM glutamate-cysteine ligase, modifier subunit 2.37995
SEC61G Sec61 gamma subunit 2.37764
HMBOX1 homeobox containing 1 2.37725
KIF3B kinesin family member 3B 2.36865
EPB42 erythrocyte membrane protein band 4.2 2.36833
SEL1L sel-1 suppressor of lin-12-like (C. elegans) 2.36802
CREB5 cAMP responsive element binding protein 5 2.36652
NPIPB5 nuclear pore complex interacting protein family, member B5 2.36452
SMARCAL1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a-like 1 2.35984
SARAF store-operated calcium entry-associated regulatory factor 2.35716
CD3D CD3d molecule, delta (CD3-TCR complex) 2.33934
UPP1 uridine phosphorylase 1 2.33568
ITPR2 inositol 1,4,5-trisphosphate receptor, type 2 2.33534
GSK3B glycogen synthase kinase 3 beta 2.3337
NIBAN1 niban apoptosis regulator 1 2.32979
CD63 CD63 molecule 2.32966
BBOF1 basal body orientation factor 1 2.32832
TBL1X transducin (beta)-like 1X-linked 2.32581
LIN7A lin-7 homolog A (C. elegans) 2.32442
PDE6G phosphodiesterase 6G, cGMP-specific, rod, gamma 2.32192
PHF20L1 PHD finger protein 20-like 1 2.31932
SNAI1 snail family zinc finger 1 2.31667
SERINC3 serine incorporator 3 2.3132
ULBP1 UL16 binding protein 1 2.31318
TCP11L1 t-complex 11, testis-specific-like 1 2.31092
MSRA methionine sulfoxide reductase A 2.31091
TP53BP1 tumor protein p53 binding protein 1 2.30971
TJP1 tight junction protein 1 2.29906
DRAP1 DR1-associated protein 1 (negative cofactor 2 alpha) 2.29763
ESYT1 extended synaptotagmin-like protein 1 2.29587
MEAF6 MYST/Esa1-associated factor 6 2.29564
CANT1 calcium activated nucleotidase 1 2.29145
SSR4 signal sequence receptor, delta 2.29024
COPB1 coatomer protein complex, subunit beta 1 2.28784
PARP6 poly (ADP-ribose) polymerase family, member 6 2.28408
AVEN apoptosis, caspase activation inhibitor 2.28172
RBKS ribokinase 2.27962
NCK2 NCK adaptor protein 2 2.27396
SPATA2L spermatogenesis associated 2-like 2.27299
RAB8B RAB8B, member RAS oncogene family 2.27227
FNDC4 fibronectin type III domain containing 4 2.27098
GLRX2 glutaredoxin 2 2.27032
EIF1 eukaryotic translation initiation factor 1 2.26894
WDR19 WD repeat domain 19 2.2689
H1-0 H1.0 linker histone 2.25706
CUL7 cullin 7 2.2537
MAFF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F 2.24777
EFHC1 EF-hand domain (C-terminal) containing 1 2.24607
MAPK6 mitogen-activated protein kinase 6 2.24106
ZC3H15 zinc finger CCCH-type containing 15 2.24047
STX8 syntaxin 8 2.23905
ERCC1 excision repair cross-complementation group 1 2.23851
GOLT1B golgi transport 1B 2.23593
RWDD2A RWD domain containing 2A 2.23591
CCDC92 coiled-coil domain containing 92 2.22853
RAB32 RAB32, member RAS oncogene family 2.22591
ENOX1 ecto-NOX disulfide-thiol exchanger 1 2.22512
TPBG trophoblast glycoprotein 2.22129
EDN1 endothelin 1 2.22102
LOC107987462 leukocyte immunoglobulin-like receptor subfamily B member 3 2.21286
RNF103 ring finger protein 103 2.20707
AKTIP AKT interacting protein 2.2067
DNAJC12 DnaJ (Hsp40) homolog, subfamily C, member 12 2.20351
FKBP14 FK506 binding protein 14, 22 kDa 2.20035
FAM114A1 family with sequence similarity 114, member A1 2.19741
ITCH itchy E3 ubiquitin protein ligase 2.19734
NOL3 nucleolar protein 3 (apoptosis repressor with CARD domain) 2.1972
DHRS4 dehydrogenase/reductase (SDR family) member 4 2.19368
EGR4 early growth response 4 2.19137
AHSP alpha hemoglobin stabilizing protein 2.19041
HSD17B8 hydroxysteroid (17-beta) dehydrogenase 8 2.18957
RAB3IL1 RAB3A interacting protein (rabin3)-like 1 2.18717
RAP1GAP RAP1 GTPase activating protein 2.18678
SPG11 spastic paraplegia 11 (autosomal recessive) 2.18608
NTRK2 neurotrophic tyrosine kinase, receptor, type 2 2.1854
ITGA2 integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) 2.18359
PAPPA pregnancy-associated plasma protein A, pappalysin 1 2.18335
TRIM8 tripartite motif containing 8 2.1797
SPX spexin hormone 2.17921
ATXN1 ataxin 1 2.17784
MRPS15 mitochondrial ribosomal protein S15 2.17692
TBC1D19 TBC1 domain family, member 19 2.17632
DDIT4 DNA-damage-inducible transcript 4 2.17554
INHBA inhibin, beta A 2.17388
POLI polymerase (DNA directed) iota 2.17332
UGGT2 UDP-glucose glycoprotein glucosyltransferase 2 2.17315
PRDM14 PR domain containing 14 2.17127
TNF tumor necrosis factor 2.16725
LOC114841035 uncharacterized LOC114841035 2.16659
WBP4 WW domain binding protein 4 2.15871
NTM neurotrimin 2.15509
SSR1 signal sequence receptor, alpha 2.15201
AQP9 aquaporin 9 2.15119
NAT9 N-acetyltransferase 9 (GCN5-related, putative) 2.15098
DNAAF11 dynein axonemal assembly factor 11 2.15005
SEMA3B sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3B 2.14298
CEMIP cell migration inducing protein, hyaluronan binding 2.14209
FUT1 fucosyltransferase 1 (galactoside 2-alpha-L-fucosyltransferase, H blood group) 2.14017
GSTZ1 glutathione S-transferase zeta 1 2.13929
ASS1 argininosuccinate synthase 1 2.13928
ELL2 elongation factor, RNA polymerase II, 2 2.13416
GRIN2C glutamate receptor, ionotropic, N-methyl D-aspartate 2C 2.13251
IDUA iduronidase, alpha-L- 2.12653
LTBR lymphotoxin beta receptor (TNFR superfamily, member 3) 2.12277
SDC4 syndecan 4 2.12128
SLC6A11 solute carrier family 6 (neurotransmitter transporter), member 11 2.12072
SHC1 SHC (Src homology 2 domain containing) transforming protein 1 2.11849
MAP3K20 mitogen-activated protein kinase kinase kinase 20 2.11473
FST follistatin 2.11343
ACOT9 acyl-CoA thioesterase 9 2.11115
RMDN1 regulator of microtubule dynamics 1 2.11084
BET1 Bet1 golgi vesicular membrane trafficking protein 2.11042
SMCP sperm mitochondria-associated cysteine-rich protein 2.10963
PIGK phosphatidylinositol glycan anchor biosynthesis, class K 2.10827
TM6SF1 transmembrane 6 superfamily member 1 2.10646
RIOK3 RIO kinase 3 2.10569
AEN apoptosis enhancing nuclease 2.10409
CCDC87 coiled-coil domain containing 87 2.09928
PYROXD1 pyridine nucleotide-disulphide oxidoreductase domain 1 2.09583
TNFRSF10B tumor necrosis factor receptor superfamily, member 10b 2.09476
RHOF ras homolog family member F (in filopodia) 2.09424
SNCA synuclein, alpha (non A4 component of amyloid precursor) 2.09283
RIPK2 receptor-interacting serine-threonine kinase 2 2.0926
ZYX zyxin 2.08791
THBS3 thrombospondin 3 2.08748
VPS52 vacuolar protein sorting 52 homolog (S. cerevisiae) 2.08621
PLK3 polo-like kinase 3 2.08576
CDK5RAP3 CDK5 regulatory subunit associated protein 3 2.08441
ELF5 E74-like factor 5 (ets domain transcription factor) 2.08417
TMEM40 transmembrane protein 40 2.07681
LMO4 LIM domain only 4 2.07669
MMP24-AS1-EDEM2 MMP24-AS1-EDEM2 readthrough 2.07432
CBX4 chromobox homolog 4 2.0728
TMED5 transmembrane emp24 protein transport domain containing 5 2.07265
NBAS neuroblastoma amplified sequence 2.07025
PPP1R11 protein phosphatase 1, regulatory (inhibitor) subunit 11 2.06747
CYB5R2 cytochrome b5 reductase 2 2.0644
BRAF B-Raf proto-oncogene, serine/threonine kinase 2.06152
RGL2 ral guanine nucleotide dissociation stimulator-like 2 2.06112
AMZ2 archaelysin family metallopeptidase 2 2.05757
BICDL1 BICD family like cargo adaptor 1 2.05697
SYN1 synapsin I 2.05431
DDAH2 dimethylarginine dimethylaminohydrolase 2 2.05419
RING1 ring finger protein 1 2.05416
ACTMAP actin maturation protease 2.05272
MSTO1 misato 1, mitochondrial distribution and morphology regulator 2.05073
FOS FBJ murine osteosarcoma viral oncogene homolog 2.04965
EIF4G3 eukaryotic translation initiation factor 4 gamma, 3 2.04394
COPG1 coatomer protein complex, subunit gamma 1 2.04057
COLGALT2 collagen beta(1-O)galactosyltransferase 2 2.04038
TMCC2 transmembrane and coiled-coil domain family 2 2.03963
APH1B APH1B gamma secretase subunit 2.03927
SV2B synaptic vesicle glycoprotein 2B 2.03799
F5 coagulation factor V (proaccelerin, labile factor) 2.0375
MICAL2 microtubule associated monooxygenase, calponin and LIM domain containing 2 2.03735
HSPA9 heat shock 70kDa protein 9 (mortalin) 2.03503
TMEM59 transmembrane protein 59 2.03465
FKBP11 FK506 binding protein 11, 19 kDa 2.03338
PLA2G4C phospholipase A2, group IVC (cytosolic, calcium-independent) 2.02783
COPZ2 coatomer protein complex, subunit zeta 2 2.02525
WASHC3 WASH complex subunit 3 2.02394
TMED10 transmembrane emp24-like trafficking protein 10 (yeast) 2.02354
MAP4K4 mitogen-activated protein kinase kinase kinase kinase 4 2.02336
CAVIN3 caveolae associated protein 3 2.02236
UNC13A unc-13 homolog A (C. elegans) 2.02056
PDE1A phosphodiesterase 1A, calmodulin-dependent 2.01814
GABRB3 gamma-aminobutyric acid (GABA) A receptor, beta 3 2.01709
MKNK2 MAP kinase interacting serine/threonine kinase 2 2.01415
DCSTAMP dendrocyte expressed seven transmembrane protein 2.01093
SETD5 SET domain containing 5 2.00879
BRINP1 bone morphogenetic protein/retinoic acid inducible neural-specific 1 2.00731
YBX2 Y box binding protein 2 2.00688
SEZ6L seizure related 6 homolog (mouse)-like 2.005
PRELID3A PRELI domain containing 3A 2.00497
OSGIN1 oxidative stress induced growth inhibitor 1 2.004

decreased expression

Symbol Name Standardized Value
S100A4 S100 calcium binding protein A4 -8.73876
DCK deoxycytidine kinase -6.70411
STMN1 stathmin 1 -6.27034
POLE2 polymerase (DNA directed), epsilon 2, accessory subunit -6.17533
PCNA proliferating cell nuclear antigen -5.85355
FEN1 flap structure-specific endonuclease 1 -5.6875
HSPB1 heat shock 27kDa protein 1 -5.61288
TCTA T-cell leukemia translocation altered -5.29101
TMEM109 transmembrane protein 109 -5.24066
MCM5 minichromosome maintenance complex component 5 -5.15467
HSPA8 heat shock 70kDa protein 8 -5.13233
HOXA5 homeobox A5 -5.10466
MCM3 minichromosome maintenance complex component 3 -5.02534
PAFAH1B3 platelet-activating factor acetylhydrolase 1b, catalytic subunit 3 (29kDa) -4.86578
GINS2 GINS complex subunit 2 (Psf2 homolog) -4.84556
CDK1 cyclin-dependent kinase 1 -4.79466
CENPM centromere protein M -4.78059
ASF1B anti-silencing function 1B histone chaperone -4.76767
SUV39H1 suppressor of variegation 3-9 homolog 1 (Drosophila) -4.75768
NUP85 nucleoporin 85kDa -4.73617
MCM6 minichromosome maintenance complex component 6 -4.69647
BIRC5 baculoviral IAP repeat containing 5 -4.67163
BAG3 BCL2-associated athanogene 3 -4.54437
CCNA2 cyclin A2 -4.53412
MCM7 minichromosome maintenance complex component 7 -4.50282
KIF11 kinesin family member 11 -4.41794
MCM10 minichromosome maintenance complex component 10 -4.38855
MYBL2 v-myb avian myeloblastosis viral oncogene homolog-like 2 -4.35329
KIF20A kinesin family member 20A -4.24504
ERCC6L excision repair cross-complementation group 6-like -4.2425
SESN1 sestrin 1 -4.19742
TSPAN6 tetraspanin 6 -4.19666
MAD2L1 MAD2 mitotic arrest deficient-like 1 (yeast) -4.16896
NUSAP1 nucleolar and spindle associated protein 1 -4.14475
ANKRD10 ankyrin repeat domain 10 -4.09325
UQCR10 ubiquinol-cytochrome c reductase, complex III subunit X -4.07926
NEIL3 nei endonuclease VIII-like 3 (E. coli) -4.04112
PSRC1 proline/serine-rich coiled-coil 1 -4.03672
CDC45 cell division cycle 45 -4.0364
RFC3 replication factor C (activator 1) 3, 38kDa -4.01288
AKT1 v-akt murine thymoma viral oncogene homolog 1 -3.99181
POLA2 polymerase (DNA directed), alpha 2, accessory subunit -3.85967
DBF4 DBF4 zinc finger -3.8131
NASP nuclear autoantigenic sperm protein (histone-binding) -3.80978
LRIG1 leucine-rich repeats and immunoglobulin-like domains 1 -3.7744
ACYP1 acylphosphatase 1, erythrocyte (common) type -3.76708
DLGAP5 discs, large (Drosophila) homolog-associated protein 5 -3.73758
GPD1L glycerol-3-phosphate dehydrogenase 1-like -3.73276
PRR15L proline rich 15-like -3.7071
CPNE3 copine III -3.70492
OAT ornithine aminotransferase -3.69934
TRIP13 thyroid hormone receptor interactor 13 -3.63345
CCNB2 cyclin B2 -3.61982
GINS1 GINS complex subunit 1 (Psf1 homolog) -3.61384
CHAF1A chromatin assembly factor 1, subunit A (p150) -3.60072
MCM4 minichromosome maintenance complex component 4 -3.59983
ELOVL6 ELOVL fatty acid elongase 6 -3.59903
MSH2 mutS homolog 2 -3.59608
SNRNP25 small nuclear ribonucleoprotein 25kDa (U11/U12) -3.56903
ALDOC aldolase C, fructose-bisphosphate -3.53315
HSD17B11 hydroxysteroid (17-beta) dehydrogenase 11 -3.51931
CCNF cyclin F -3.51704
B4GAT1 beta-1,4-glucuronyltransferase 1 -3.4735
UBR7 ubiquitin protein ligase E3 component n-recognin 7 (putative) -3.47026
DHFR dihydrofolate reductase -3.46669
RFC2 replication factor C (activator 1) 2, 40kDa -3.44478
FOXM1 forkhead box M1 -3.4374
DNM1 dynamin 1 -3.43681
CDC20 cell division cycle 20 -3.4174
COX16 COX16 cytochrome c oxidase assembly homolog (S. cerevisiae) -3.40289
GINS3 GINS complex subunit 3 (Psf3 homolog) -3.37631
SDHAF3 succinate dehydrogenase complex assembly factor 3 -3.3615
MCMBP minichromosome maintenance complex binding protein -3.32641
SYNE2 spectrin repeat containing, nuclear envelope 2 -3.31856
CCNB1 cyclin B1 -3.31003
KIF14 kinesin family member 14 -3.30647
SPC25 SPC25, NDC80 kinetochore complex component -3.30448
CDK2 cyclin-dependent kinase 2 -3.29787
NSMCE4A non-SMC element 4 homolog A (S. cerevisiae) -3.28687
KIF18B kinesin family member 18B -3.27713
PRKAR2B protein kinase, cAMP-dependent, regulatory, type II, beta -3.25363
CHAF1B chromatin assembly factor 1, subunit B (p60) -3.24547
PARP1 poly (ADP-ribose) polymerase 1 -3.24133
HADH hydroxyacyl-CoA dehydrogenase -3.23354
TMPO thymopoietin -3.22734
SQOR sulfide quinone oxidoreductase -3.22689
PRPF31 pre-mRNA processing factor 31 -3.21446
NUP62 nucleoporin 62kDa -3.19237
TMEM14A transmembrane protein 14A -3.17985
ZNF274 zinc finger protein 274 -3.17423
CCND3 cyclin D3 -3.17004
CDT1 chromatin licensing and DNA replication factor 1 -3.16848
KIF4A kinesin family member 4A -3.16529
TK1 thymidine kinase 1, soluble -3.15367
DSCC1 DNA replication and sister chromatid cohesion 1 -3.14152
VRK1 vaccinia related kinase 1 -3.13484
XRCC6 X-ray repair complementing defective repair in Chinese hamster cells 6 -3.12508
RMI1 RecQ mediated genome instability 1 -3.12221
NAT10 N-acetyltransferase 10 (GCN5-related) -3.10518
UNG uracil-DNA glycosylase -3.09507
POLR2H polymerase (RNA) II (DNA directed) polypeptide H -3.07738
PYDC1 PYD (pyrin domain) containing 1 -3.05597
CUTC cutC copper transporter -3.05292
NCAPD3 non-SMC condensin II complex, subunit D3 -3.04621
KRT13 keratin 13, type I -3.04332
ZNF813 zinc finger protein 813 -3.03128
AURKA aurora kinase A -3.01224
SLC25A10 solute carrier family 25 (mitochondrial carrier; dicarboxylate transporter), member 10 -3.00844
POLR1A polymerase (RNA) I polypeptide A, 194kDa -3.00034
ADI1 acireductone dioxygenase 1 -2.99321
SNX10 sorting nexin 10 -2.9839
DHX29 DEAH (Asp-Glu-Ala-His) box polypeptide 29 -2.97041
DNA2 DNA replication helicase/nuclease 2 -2.9615
RAD51AP1 RAD51 associated protein 1 -2.94138
DTL denticleless E3 ubiquitin protein ligase homolog (Drosophila) -2.94118
NUP160 nucleoporin 160kDa -2.93909
MRPL12 mitochondrial ribosomal protein L12 -2.9283
LMNB1 lamin B1 -2.9232
BRCA1 breast cancer 1, early onset -2.90772
NCAPD2 non-SMC condensin I complex, subunit D2 -2.90546
PRKCD protein kinase C, delta -2.90402
PGAM4 phosphoglycerate mutase family member 4 -2.8986
ANP32A acidic (leucine-rich) nuclear phosphoprotein 32 family, member A -2.89635
GPR88 G protein-coupled receptor 88 -2.89501
OIP5 Opa interacting protein 5 -2.87113
SNRPA small nuclear ribonucleoprotein polypeptide A -2.86521
CD320 CD320 molecule -2.84922
PAXIP1 PAX interacting (with transcription-activation domain) protein 1 -2.84897
FKBP5 FK506 binding protein 5 -2.82864
PRPF4 pre-mRNA processing factor 4 -2.82726
CRYZ crystallin, zeta (quinone reductase) -2.8222
PRKD3 protein kinase D3 -2.81949
RGS2 regulator of G-protein signaling 2 -2.79958
DNMT1 DNA (cytosine-5-)-methyltransferase 1 -2.79605
WDHD1 WD repeat and HMG-box DNA binding protein 1 -2.79306
FANCI Fanconi anemia, complementation group I -2.78916
RAD51C RAD51 paralog C -2.78393
NEK2 NIMA-related kinase 2 -2.78294
HMGB2 high mobility group box 2 -2.77979
PSME1 proteasome (prosome, macropain) activator subunit 1 (PA28 alpha) -2.75992
GPS1 G protein pathway suppressor 1 -2.75508
RRM1 ribonucleotide reductase M1 -2.74755
POLR3K polymerase (RNA) III (DNA directed) polypeptide K, 12.3 kDa -2.73897
DDX23 DEAD (Asp-Glu-Ala-Asp) box polypeptide 23 -2.73272
EGLN1 egl-9 family hypoxia-inducible factor 1 -2.72786
NDUFA8 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 8, 19kDa -2.72535
CEP55 centrosomal protein 55kDa -2.72312
PPM1G protein phosphatase, Mg2+/Mn2+ dependent, 1G -2.71744
CROT carnitine O-octanoyltransferase -2.70878
CKAP2 cytoskeleton associated protein 2 -2.70413
FIRRM FIGNL1 interacting regulator of recombination and mitosis -2.69661
HACD3 3-hydroxyacyl-CoA dehydratase 3 -2.6953
CHEK1 checkpoint kinase 1 -2.68911
ZWINT ZW10 interacting kinetochore protein -2.6799
PRR5 proline rich 5 (renal) -2.67292
SH3GLB2 SH3-domain GRB2-like endophilin B2 -2.67015
CTNNAL1 catenin (cadherin-associated protein), alpha-like 1 -2.66694
CDCA3 cell division cycle associated 3 -2.66453
UBAC1 UBA domain containing 1 -2.65999
ZDHHC6 zinc finger, DHHC-type containing 6 -2.65867
ZNF107 zinc finger protein 107 -2.65866
MORC3 MORC family CW-type zinc finger 3 -2.65634
RPA3 replication protein A3, 14kDa -2.6538
PDSS1 prenyl (decaprenyl) diphosphate synthase, subunit 1 -2.64788
PSMA2 proteasome (prosome, macropain) subunit, alpha type, 2 -2.64157
PGRMC1 progesterone receptor membrane component 1 -2.63481
GTF2A2 general transcription factor IIA, 2, 12kDa -2.62882
CDC6 cell division cycle 6 -2.62833
SLC46A3 solute carrier family 46, member 3 -2.62571
CDC7 cell division cycle 7 -2.62503
MYC v-myc avian myelocytomatosis viral oncogene homolog -2.61738
ATAD2 ATPase family, AAA domain containing 2 -2.61646
XPNPEP1 X-prolyl aminopeptidase (aminopeptidase P) 1, soluble -2.60914
SRSF3 serine/arginine-rich splicing factor 3 -2.6077
DNAJA1 DnaJ (Hsp40) homolog, subfamily A, member 1 -2.6049
AURKB aurora kinase B -2.60347
TATDN2 TatD DNase domain containing 2 -2.58848
KCNA3 potassium channel, voltage gated shaker related subfamily A, member 3 -2.57392
PWP2 PWP2 periodic tryptophan protein homolog (yeast) -2.57389
HOXA4 homeobox A4 -2.5732
DUT deoxyuridine triphosphatase -2.57246
ELAC2 elaC ribonuclease Z 2 -2.56924
NUP107 nucleoporin 107kDa -2.56665
RRM2 ribonucleotide reductase M2 -2.56155
RBL1 retinoblastoma-like 1 -2.55908
GLO1 glyoxalase I -2.5503
NAP1L4 nucleosome assembly protein 1-like 4 -2.54898
SMNDC1 survival motor neuron domain containing 1 -2.54743
H2AC25 H2A clustered histone 25 -2.52948
PFKM phosphofructokinase, muscle -2.52742
ZBTB24 zinc finger and BTB domain containing 24 -2.52372
KDM3B lysine (K)-specific demethylase 3B -2.52264
RLIG1 RNA 5'-phosphate and 3'-OH ligase 1 -2.52027
STARD7 StAR-related lipid transfer (START) domain containing 7 -2.51479
RACGAP1 Rac GTPase activating protein 1 -2.51124
HMGB1 high mobility group box 1 -2.50718
IRF2 interferon regulatory factor 2 -2.50715
TLE1 transducin-like enhancer of split 1 (E(sp1) homolog, Drosophila) -2.50138
SMARCD2 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 2 -2.49998
PLCB3 phospholipase C, beta 3 (phosphatidylinositol-specific) -2.49616
HDAC2 histone deacetylase 2 -2.48857
GEMIN4 gem (nuclear organelle) associated protein 4 -2.48688
MRM2 mitochondrial rRNA methyltransferase 2 -2.48662
POLD1 polymerase (DNA directed), delta 1, catalytic subunit -2.48611
SYPL1 synaptophysin-like 1 -2.48081
HELLS helicase, lymphoid-specific -2.47654
RFC4 replication factor C (activator 1) 4, 37kDa -2.47446
PARPBP PARP1 binding protein -2.46905
MYCBP MYC binding protein -2.46319
PLEKHJ1 pleckstrin homology domain containing, family J member 1 -2.45061
CENPX centromere protein X -2.44999
ATF5 activating transcription factor 5 -2.44994
PPIH peptidylprolyl isomerase H (cyclophilin H) -2.43755
MIS18A MIS18 kinetochore protein A -2.42899
CCT8 chaperonin containing TCP1, subunit 8 (theta) -2.42793
MCM9 minichromosome maintenance complex component 9 -2.42761
EIF4ENIF1 eukaryotic translation initiation factor 4E nuclear import factor 1 -2.42621
SERPINF1 serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1 -2.4251
CYCS cytochrome c, somatic -2.41571
E2F8 E2F transcription factor 8 -2.41424
MSH6 mutS homolog 6 -2.41186
CORO7-PAM16 CORO7-PAM16 readthrough -2.41107
PSMB10 proteasome (prosome, macropain) subunit, beta type, 10 -2.40844
ADH5 alcohol dehydrogenase 5 (class III), chi polypeptide -2.40245
SLC37A4 solute carrier family 37 (glucose-6-phosphate transporter), member 4 -2.40151
BORA bora, aurora kinase A activator -2.39904
ABCC4 ATP-binding cassette, sub-family C (CFTR/MRP), member 4 -2.39887
RFC5 replication factor C (activator 1) 5, 36.5kDa -2.39588
POP5 processing of precursor 5, ribonuclease P/MRP subunit (S. cerevisiae) -2.39351
SRSF2 serine/arginine-rich splicing factor 2 -2.38559
DDX39A DEAD (Asp-Glu-Ala-Asp) box polypeptide 39A -2.38228
NUP93 nucleoporin 93kDa -2.37916
CENPA centromere protein A -2.37854
PBK PDZ binding kinase -2.37128
PRMT7 protein arginine methyltransferase 7 -2.37011
NELFB negative elongation factor complex member B -2.36466
NELFCD negative elongation factor complex member C/D -2.35901
CBR3 carbonyl reductase 3 -2.35892
DPH2 DPH2 homolog (S. cerevisiae) -2.35754
RUVBL2 RuvB-like AAA ATPase 2 -2.35678
PLS1 plastin 1 -2.35656
SINHCAF SIN3-HDAC complex associated factor -2.35386
ITGB3BP integrin beta 3 binding protein (beta3-endonexin) -2.35198
GYS1 glycogen synthase 1 (muscle) -2.3459
HMGB3 high mobility group box 3 -2.34518
CAAP1 caspase activity and apoptosis inhibitor 1 -2.33512
TMSB10 thymosin beta 10 -2.33333
BACE2 beta-site APP-cleaving enzyme 2 -2.33011
PRC1 protein regulator of cytokinesis 1 -2.32908
CBX3 chromobox homolog 3 -2.32777
XPO1 exportin 1 -2.3272
APOBEC3C apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3C -2.32646
MKI67 marker of proliferation Ki-67 -2.32284
POLE3 polymerase (DNA directed), epsilon 3, accessory subunit -2.31053
NLRP2B NLR family pyrin domain containing 2B -2.31046
HMG20B high mobility group 20B -2.30866
IL18 interleukin 18 -2.30645
SHQ1 SHQ1, H/ACA ribonucleoprotein assembly factor -2.30524
NTHL1 nth endonuclease III-like 1 (E. coli) -2.30421
RBM14-RBM4 RBM14-RBM4 readthrough -2.29678
RANGAP1 Ran GTPase activating protein 1 -2.29103
HAUS7 HAUS augmin-like complex, subunit 7 -2.29047
PRPF38B pre-mRNA processing factor 38B -2.28795
YEATS4 YEATS domain containing 4 -2.28678
POLR2L polymerase (RNA) II (DNA directed) polypeptide L, 7.6kDa -2.2864
POLR2K polymerase (RNA) II (DNA directed) polypeptide K, 7.0kDa -2.28443
CSTF1 cleavage stimulation factor, 3' pre-RNA, subunit 1, 50kDa -2.28219
GMNN geminin, DNA replication inhibitor -2.28163
LINC02762 long intergenic non-protein coding RNA 2762 -2.27647
BICD2 bicaudal D homolog 2 (Drosophila) -2.27588
ZNF207 zinc finger protein 207 -2.27465
KIF15 kinesin family member 15 -2.2702
HSPE1 heat shock 10kDa protein 1 -2.26731
PLK1 polo-like kinase 1 -2.26711
FBXO5 F-box protein 5 -2.26495
IRAK1 interleukin-1 receptor-associated kinase 1 -2.26395
TMX1 thioredoxin-related transmembrane protein 1 -2.26383
TIMM8A translocase of inner mitochondrial membrane 8 homolog A (yeast) -2.2536
TUBA1B tubulin, alpha 1b -2.25054
CDC42EP4 CDC42 effector protein (Rho GTPase binding) 4 -2.24749
THUMPD2 THUMP domain containing 2 -2.24389
UBE2L3 ubiquitin-conjugating enzyme E2L 3 -2.23114
GOLM1 golgi membrane protein 1 -2.23074
HNRNPM heterogeneous nuclear ribonucleoprotein M -2.22151
NCAPH non-SMC condensin I complex, subunit H -2.22085
KDM1A lysine (K)-specific demethylase 1A -2.21851
SPDL1 spindle apparatus coiled-coil protein 1 -2.21819
SNRPB small nuclear ribonucleoprotein polypeptides B and B1 -2.2155
TMEM50A transmembrane protein 50A -2.21232
ARHGAP11A Rho GTPase activating protein 11A -2.20652
TCEA2 transcription elongation factor A (SII), 2 -2.20462
WDR76 WD repeat domain 76 -2.19551
ADGRE5 adhesion G protein-coupled receptor E5 -2.19532
ARHGDIB Rho GDP dissociation inhibitor (GDI) beta -2.19266
EXOSC9 exosome component 9 -2.19242
ITGAE integrin, alpha E (antigen CD103, human mucosal lymphocyte antigen 1; alpha polypeptide) -2.19201
YKT6 YKT6 v-SNARE homolog (S. cerevisiae) -2.1919
SUZ12 SUZ12 polycomb repressive complex 2 subunit -2.18909
KBTBD4 kelch repeat and BTB (POZ) domain containing 4 -2.18798
NUDT1 nudix (nucleoside diphosphate linked moiety X)-type motif 1 -2.18731
DTYMK deoxythymidylate kinase (thymidylate kinase) -2.18534
TSPAN3 tetraspanin 3 -2.18203
CLN6 ceroid-lipofuscinosis, neuronal 6, late infantile, variant -2.1816
MRPS2 mitochondrial ribosomal protein S2 -2.18089
TPD52-MRPS28 TPD52-MRPS28 readthrough -2.17939
B4GALT5 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 -2.17674
POLR1G RNA polymerase I subunit G -2.17648
INSIG1 insulin induced gene 1 -2.17256
TDRD7 tudor domain containing 7 -2.17157
FAM32A family with sequence similarity 32, member A -2.17017
PSMD3 proteasome (prosome, macropain) 26S subunit, non-ATPase, 3 -2.1694
EXO1 exonuclease 1 -2.16725
CD207 CD207 molecule, langerin -2.15943
TNFSF10 tumor necrosis factor (ligand) superfamily, member 10 -2.15698
MPC2 mitochondrial pyruvate carrier 2 -2.15542
DBR1 debranching RNA lariats 1 -2.15425
CS citrate synthase -2.15284
POLR2D polymerase (RNA) II (DNA directed) polypeptide D -2.15124
POLR2F polymerase (RNA) II (DNA directed) polypeptide F -2.15018
POLA1 polymerase (DNA directed), alpha 1, catalytic subunit -2.14664
RNF38 ring finger protein 38 -2.14643
BID BH3 interacting domain death agonist -2.14617
BZW2 basic leucine zipper and W2 domains 2 -2.1428
IRAG2 inositol 1,4,5-triphosphate receptor associated 2 -2.14278
SMC4 structural maintenance of chromosomes 4 -2.14227
ANAPC15 anaphase promoting complex subunit 15 -2.14224
JPT2 Jupiter microtubule associated homolog 2 -2.1422
ATRIP ATR interacting protein -2.13989
SHROOM2 shroom family member 2 -2.13684
AMDHD2 amidohydrolase domain containing 2 -2.13532
CDC25A cell division cycle 25A -2.13335
FBXO34 F-box protein 34 -2.1277
ADRB2 adrenoceptor beta 2, surface -2.12618
FCER1A Fc fragment of IgE, high affinity I, receptor for; alpha polypeptide -2.12226
GSTP1 glutathione S-transferase pi 1 -2.11821
TOMM22 translocase of outer mitochondrial membrane 22 homolog (yeast) -2.11815
TFDP1 transcription factor Dp-1 -2.11644
TIMELESS timeless circadian clock -2.11353
DEAF1 DEAF1 transcription factor -2.11247
HNRNPA2B1 heterogeneous nuclear ribonucleoprotein A2/B1 -2.11191
FABP5 fatty acid binding protein 5 (psoriasis-associated) -2.11169
CHCHD7 coiled-coil-helix-coiled-coil-helix domain containing 7 -2.11032
CKS2 CDC28 protein kinase regulatory subunit 2 -2.10897
PHF2 PHD finger protein 2 -2.10886
PSME3 proteasome (prosome, macropain) activator subunit 3 (PA28 gamma; Ki) -2.10472
DNTTIP2 deoxynucleotidyltransferase, terminal, interacting protein 2 -2.10467
CIAPIN1 cytokine induced apoptosis inhibitor 1 -2.10407
GGA3 golgi-associated, gamma adaptin ear containing, ARF binding protein 3 -2.10244
DNAAF2 dynein, axonemal, assembly factor 2 -2.09847
POLM polymerase (DNA directed), mu -2.09807
ARHGAP8 Rho GTPase activating protein 8 -2.0965
DTX4 deltex 4, E3 ubiquitin ligase -2.09516
MRPL49 mitochondrial ribosomal protein L49 -2.09411
FGFR3 fibroblast growth factor receptor 3 -2.09332
PSME2 proteasome (prosome, macropain) activator subunit 2 (PA28 beta) -2.09187
SLC22A5 solute carrier family 22 (organic cation/carnitine transporter), member 5 -2.09145
HPS5 Hermansky-Pudlak syndrome 5 -2.09063
DONSON downstream neighbor of SON -2.08985
MRPS34 mitochondrial ribosomal protein S34 -2.08937
ATAD5 ATPase family, AAA domain containing 5 -2.08697
CCDC86 coiled-coil domain containing 86 -2.08634
SYNJ2BP synaptojanin 2 binding protein -2.08604
UBAP2L ubiquitin associated protein 2-like -2.07969
TFCP2L1 transcription factor CP2-like 1 -2.07969
TMEM160 transmembrane protein 160 -2.07876
SPON1 spondin 1, extracellular matrix protein -2.07801
SERHL2 serine hydrolase-like 2 -2.07694
PHTF2 putative homeodomain transcription factor 2 -2.0766
CLN5 ceroid-lipofuscinosis, neuronal 5 -2.07411
PLSCR1 phospholipid scramblase 1 -2.07333
PRUNE1 prune exopolyphosphatase 1 -2.07108
DAG1 dystroglycan 1 (dystrophin-associated glycoprotein 1) -2.06749
CDC25B cell division cycle 25B -2.06681
NOL8 nucleolar protein 8 -2.06507
HNRNPR heterogeneous nuclear ribonucleoprotein R -2.06255
MRPS27 mitochondrial ribosomal protein S27 -2.06241
UBP1 upstream binding protein 1 (LBP-1a) -2.06235
RPIA ribose 5-phosphate isomerase A -2.05209
DSN1 DSN1, MIS12 kinetochore complex component -2.05024
FZD7 frizzled class receptor 7 -2.05021
RAPGEFL1 Rap guanine nucleotide exchange factor (GEF)-like 1 -2.04949
HSDL2 hydroxysteroid dehydrogenase like 2 -2.0478
HMCES 5-hydroxymethylcytosine (hmC) binding, ES cell-specific -2.0477
TARBP1 TAR (HIV-1) RNA binding protein 1 -2.04328
VAV3 vav 3 guanine nucleotide exchange factor -2.04003
LBR lamin B receptor -2.03802
FN3KRP fructosamine 3 kinase related protein -2.03795
MAGEA12 melanoma antigen family A12 -2.03736
MVP major vault protein -2.03688
THOP1 thimet oligopeptidase 1 -2.03687
DNAJC15 DnaJ (Hsp40) homolog, subfamily C, member 15 -2.03564
NR2F6 nuclear receptor subfamily 2, group F, member 6 -2.03526
TSC22D3 TSC22 domain family, member 3 -2.03336
CISD1 CDGSH iron sulfur domain 1 -2.03288
TCOF1 Treacher Collins-Franceschetti syndrome 1 -2.03156
TUBB4B tubulin, beta 4B class IVb -2.03149
UNC119 unc-119 homolog (C. elegans) -2.03137
MRPS7 mitochondrial ribosomal protein S7 -2.02937
IPO9 importin 9 -2.02807
NSDHL NAD(P) dependent steroid dehydrogenase-like -2.0276
ATAD2B ATPase family, AAA domain containing 2B -2.02718
FAM234B family with sequence similarity 234 member B -2.02543
STEAP4 STEAP family member 4 -2.02484
NMU neuromedin U -2.02263
HOXA2 homeobox A2 -2.02126
COA1 cytochrome c oxidase assembly factor 1 homolog (S. cerevisiae) -2.01968
RPP30 ribonuclease P/MRP 30kDa subunit -2.01632
KYAT1 kynurenine aminotransferase 1 -2.01371
AHSA1 AHA1, activator of heat shock 90kDa protein ATPase homolog 1 (yeast) -2.01264
PSMB3 proteasome (prosome, macropain) subunit, beta type, 3 -2.01088
FMR1 fragile X mental retardation 1 -2.00865
UXT ubiquitously-expressed, prefoldin-like chaperone -2.00633
TRAP1 TNF receptor-associated protein 1 -2.00303