CRCGN017_MCF10A.TP53.M_24H:H14 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description benzoin 33.49 um perturbation at 24 h in MCF10A.TP53.M (Carcinogenome)
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Genes

30 genes differentially expressed following the CRCGN017_MCF10A.TP53.M_24H:H14 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
SSBP2 single-stranded DNA binding protein 2 8.70558
OXSR1 oxidative stress responsive 1 4.87982
SPAG4 sperm associated antigen 4 4.57889
PPOX protoporphyrinogen oxidase 4.39463
CERK ceramide kinase 3.65272
NUCB2 nucleobindin 2 3.44793
ABHD6 abhydrolase domain containing 6 3.39992
SNX11 sorting nexin 11 2.74782
BAMBI BMP and activin membrane-bound inhibitor 2.65484
PLEKHJ1 pleckstrin homology domain containing, family J member 1 2.26112
GSTZ1 glutathione S-transferase zeta 1 2.05688
EGLN2 egl-9 family hypoxia-inducible factor 2 2.05394
SATB1 SATB homeobox 1 2.01703

decreased expression

Symbol Name Standardized Value
CCDC86 coiled-coil domain containing 86 -5.83205
H2BC21 H2B clustered histone 21 -5.28307
SCYL3 SCY1-like 3 (S. cerevisiae) -4.7538
LDHD lactate dehydrogenase D -4.40671
PPP2R5E protein phosphatase 2, regulatory subunit B', epsilon isoform -4.04753
HMG20B high mobility group 20B -3.94213
HOXA5 homeobox A5 -3.53407
LAMB1 laminin, beta 1 -2.64581
ALDH7A1 aldehyde dehydrogenase 7 family, member A1 -2.44617
NAMPT nicotinamide phosphoribosyltransferase -2.30295
DUS4L dihydrouridine synthase 4-like (S. cerevisiae) -2.27035
COG5 component of oligomeric golgi complex 5 -2.24162
TRIB3 tribbles pseudokinase 3 -2.1529
ANKRD10 ankyrin repeat domain 10 -2.08624
TM9SF2 transmembrane 9 superfamily member 2 -2.08069
RINT1 RAD50 interactor 1 -2.07475
BCAP29 B-cell receptor-associated protein 29 -2.03502