CRCGN017_MCF10A.TP53.M_24H:H15 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description benzoin 11.16 um perturbation at 24 h in MCF10A.TP53.M (Carcinogenome)
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Genes

25 genes differentially expressed following the CRCGN017_MCF10A.TP53.M_24H:H15 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
ABCC5 ATP-binding cassette, sub-family C (CFTR/MRP), member 5 4.55126
AGR2 anterior gradient 2 2.57593
COMP cartilage oligomeric matrix protein 2.29665
CNRIP1 cannabinoid receptor interacting protein 1 2.17051
TIMM22 translocase of inner mitochondrial membrane 22 homolog (yeast) 2.13705

decreased expression

Symbol Name Standardized Value
HMG20B high mobility group 20B -8.16761
KRT14 keratin 14, type I -6.46057
WASHC4 WASH complex subunit 4 -4.85354
CHMP4B charged multivesicular body protein 4B -4.79653
MSN moesin -3.3522
TXNDC9 thioredoxin domain containing 9 -2.61723
RBM34 RNA binding motif protein 34 -2.59423
OSBPL8 oxysterol binding protein-like 8 -2.36745
SALL1 spalt-like transcription factor 1 -2.34078
DPPA4 developmental pluripotency associated 4 -2.27597
BCL2L13 BCL2-like 13 (apoptosis facilitator) -2.25653
ACTR6 ARP6 actin-related protein 6 homolog (yeast) -2.21516
CD81 CD81 molecule -2.1786
BMP5 bone morphogenetic protein 5 -2.14911
NOPCHAP1 NOP protein chaperone 1 -2.08683
MFSD12 major facilitator superfamily domain containing 12 -2.05303
PIP5K1C phosphatidylinositol-4-phosphate 5-kinase, type I, gamma -2.02301
GGPS1 geranylgeranyl diphosphate synthase 1 -2.01925
L1TD1 LINE-1 type transposase domain containing 1 -2.01577
H1-0 H1.0 linker histone -2.00743