CRCGN017_MCF10A.TP53.M_24H:H17 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description caffeine 33.99 um perturbation at 24 h in MCF10A.TP53.M (Carcinogenome)
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Genes

15 genes differentially expressed following the CRCGN017_MCF10A.TP53.M_24H:H17 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
COMP cartilage oligomeric matrix protein 3.97868
TBX2 T-box 2 3.96517
STAP2 signal transducing adaptor family member 2 3.35753
TIMM17B translocase of inner mitochondrial membrane 17 homolog B (yeast) 2.39518

decreased expression

Symbol Name Standardized Value
STUB1 STIP1 homology and U-box containing protein 1, E3 ubiquitin protein ligase -4.17287
DHRS7 dehydrogenase/reductase (SDR family) member 7 -4.10732
PSMB8 proteasome (prosome, macropain) subunit, beta type, 8 -3.92776
HMG20B high mobility group 20B -3.86044
AKR7A2 aldo-keto reductase family 7, member A2 (aflatoxin aldehyde reductase) -3.0405
G3BP1 GTPase activating protein (SH3 domain) binding protein 1 -2.5932
SPAG7 sperm associated antigen 7 -2.33348
HIF1A hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) -2.18901
SPSB3 splA/ryanodine receptor domain and SOCS box containing 3 -2.13505
ANTKMT adenine nucleotide translocase lysine methyltransferase -2.0919
AKR7A3 aldo-keto reductase family 7, member A3 (aflatoxin aldehyde reductase) -2.01445