CRCGN017_MCF10A.TP53.M_24H:H20 Gene Set
Genes
35 genes differentially expressed following the CRCGN017_MCF10A.TP53.M_24H:H20 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
KLHL21
|
kelch-like family member 21
|
4.94964
|
|
OLFML2B
|
olfactomedin-like 2B
|
3.75984
|
|
MINDY1
|
MINDY lysine 48 deubiquitinase 1
|
3.47274
|
|
ACAA1
|
acetyl-CoA acyltransferase 1
|
3.02853
|
|
VGLL4
|
vestigial-like family member 4
|
2.97476
|
|
FZD7
|
frizzled class receptor 7
|
2.66085
|
|
RBP4
|
retinol binding protein 4, plasma
|
2.50846
|
|
NCK1
|
NCK adaptor protein 1
|
2.49555
|
|
KIF23
|
kinesin family member 23
|
2.37553
|
|
VPS28
|
vacuolar protein sorting 28 homolog (S. cerevisiae)
|
2.29443
|
|
TOMM34
|
translocase of outer mitochondrial membrane 34
|
2.2653
|
|
MIA
|
melanoma inhibitory activity
|
2.19859
|
|
DCP2
|
decapping mRNA 2
|
2.15221
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
SLC7A5
|
solute carrier family 7 (amino acid transporter light chain, L system), member 5
|
-5.12087
|
|
TM9SF3
|
transmembrane 9 superfamily member 3
|
-4.94749
|
|
CYCS
|
cytochrome c, somatic
|
-4.35733
|
|
CDC20
|
cell division cycle 20
|
-4.01826
|
|
ELOVL1
|
ELOVL fatty acid elongase 1
|
-3.32705
|
|
PRUNE2
|
prune homolog 2 (Drosophila)
|
-3.09807
|
|
LSM5
|
LSM5 homolog, U6 small nuclear RNA associated (S. cerevisiae)
|
-2.94312
|
|
GRN
|
granulin
|
-2.70857
|
|
PPCS
|
phosphopantothenoylcysteine synthetase
|
-2.67741
|
|
BASP1
|
brain abundant, membrane attached signal protein 1
|
-2.67182
|
|
TIMELESS
|
timeless circadian clock
|
-2.37524
|
|
EXO5
|
exonuclease 5
|
-2.26908
|
|
LOC107986346
|
mitochondrial import receptor subunit TOM7 homolog
|
-2.21263
|
|
HSPA1A
|
heat shock 70kDa protein 1A
|
-2.16634
|
|
CCS
|
copper chaperone for superoxide dismutase
|
-2.13479
|
|
ATP4B
|
ATPase, H+/K+ exchanging, beta polypeptide
|
-2.12123
|
|
FCER1G
|
Fc fragment of IgE, high affinity I, receptor for; gamma polypeptide
|
-2.10467
|
|
TKT
|
transketolase
|
-2.08615
|
|
CBLIF
|
cobalamin binding intrinsic factor
|
-2.06138
|
|
SLAMF1
|
signaling lymphocytic activation molecule family member 1
|
-2.02253
|
|
TRIM58
|
tripartite motif containing 58
|
-2.01402
|
|
GABRB1
|
gamma-aminobutyric acid (GABA) A receptor, beta 1
|
-2.0135
|