CRCGN017_MCF10A.TP53.M_24H:H20 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description 1,3-propane sultone 33.43 um perturbation at 24 h in MCF10A.TP53.M (Carcinogenome)
Similar Terms
Downloads & Tools

Genes

35 genes differentially expressed following the CRCGN017_MCF10A.TP53.M_24H:H20 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
KLHL21 kelch-like family member 21 4.94964
OLFML2B olfactomedin-like 2B 3.75984
MINDY1 MINDY lysine 48 deubiquitinase 1 3.47274
ACAA1 acetyl-CoA acyltransferase 1 3.02853
VGLL4 vestigial-like family member 4 2.97476
FZD7 frizzled class receptor 7 2.66085
RBP4 retinol binding protein 4, plasma 2.50846
NCK1 NCK adaptor protein 1 2.49555
KIF23 kinesin family member 23 2.37553
VPS28 vacuolar protein sorting 28 homolog (S. cerevisiae) 2.29443
TOMM34 translocase of outer mitochondrial membrane 34 2.2653
MIA melanoma inhibitory activity 2.19859
DCP2 decapping mRNA 2 2.15221

decreased expression

Symbol Name Standardized Value
SLC7A5 solute carrier family 7 (amino acid transporter light chain, L system), member 5 -5.12087
TM9SF3 transmembrane 9 superfamily member 3 -4.94749
CYCS cytochrome c, somatic -4.35733
CDC20 cell division cycle 20 -4.01826
ELOVL1 ELOVL fatty acid elongase 1 -3.32705
PRUNE2 prune homolog 2 (Drosophila) -3.09807
LSM5 LSM5 homolog, U6 small nuclear RNA associated (S. cerevisiae) -2.94312
GRN granulin -2.70857
PPCS phosphopantothenoylcysteine synthetase -2.67741
BASP1 brain abundant, membrane attached signal protein 1 -2.67182
TIMELESS timeless circadian clock -2.37524
EXO5 exonuclease 5 -2.26908
LOC107986346 mitochondrial import receptor subunit TOM7 homolog -2.21263
HSPA1A heat shock 70kDa protein 1A -2.16634
CCS copper chaperone for superoxide dismutase -2.13479
ATP4B ATPase, H+/K+ exchanging, beta polypeptide -2.12123
FCER1G Fc fragment of IgE, high affinity I, receptor for; gamma polypeptide -2.10467
TKT transketolase -2.08615
CBLIF cobalamin binding intrinsic factor -2.06138
SLAMF1 signaling lymphocytic activation molecule family member 1 -2.02253
TRIM58 tripartite motif containing 58 -2.01402
GABRB1 gamma-aminobutyric acid (GABA) A receptor, beta 1 -2.0135