CRCGN017_MCF10A.TP53.M_24H:I01 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description o-aminoazotoluene 99.8 um perturbation at 24 h in MCF10A.TP53.M (Carcinogenome)
Similar Terms
Downloads & Tools

Genes

686 genes differentially expressed following the CRCGN017_MCF10A.TP53.M_24H:I01 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
NUCB2 nucleobindin 2 7.5243
CCP110 centriolar coiled coil protein 110kDa 5.86165
IL1B interleukin 1, beta 5.48073
CXCL2 chemokine (C-X-C motif) ligand 2 4.9031
SQOR sulfide quinone oxidoreductase 4.8623
GLRX glutaredoxin (thioltransferase) 4.81382
KCTD14 potassium channel tetramerization domain containing 14 4.34888
WFS1 Wolfram syndrome 1 (wolframin) 4.31915
NOSIP nitric oxide synthase interacting protein 3.98615
EMSY EMSY transcriptional repressor, BRCA2 interacting 3.96635
RSF1 remodeling and spacing factor 1 3.73925
BAD BCL2-associated agonist of cell death 3.61415
IER3 immediate early response 3 3.51955
MAP3K20 mitogen-activated protein kinase kinase kinase 20 3.5004
SQSTM1 sequestosome 1 3.47515
GAB2 GRB2-associated binding protein 2 3.39015
NIT1 nitrilase 1 3.3666
IRF9 interferon regulatory factor 9 3.36595
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) 3.35275
IL4R interleukin 4 receptor 3.34435
HBA1 hemoglobin, alpha 1 3.32679
UBQLN2 ubiquilin 2 3.3057
DFFA DNA fragmentation factor, 45kDa, alpha polypeptide 3.26755
MX1 MX dynamin-like GTPase 1 3.25075
AAMDC adipogenesis associated, Mth938 domain containing 3.22752
EIF3G eukaryotic translation initiation factor 3, subunit G 3.21215
TRIB1 tribbles pseudokinase 1 3.2087
CKAP4 cytoskeleton-associated protein 4 3.1933
CTTN cortactin 3.19262
KCTD5 potassium channel tetramerization domain containing 5 3.1804
YTHDF1 YTH N(6)-methyladenosine RNA binding protein 1 3.1717
PRAF2 PRA1 domain family, member 2 3.14515
TXNRD1 thioredoxin reductase 1 3.13745
DCTN1 dynactin 1 3.13702
ZNF652 zinc finger protein 652 3.11595
STX4 syntaxin 4 3.0901
NOD2 nucleotide-binding oligomerization domain containing 2 3.0786
FADD Fas (TNFRSF6)-associated via death domain 3.0608
EIF2B4 eukaryotic translation initiation factor 2B, subunit 4 delta, 67kDa 3.04967
IL15RA interleukin 15 receptor, alpha 3.0472
AGR2 anterior gradient 2 3.03825
UBE2L6 ubiquitin-conjugating enzyme E2L 6 3.0366
DPF2 D4, zinc and double PHD fingers family 2 3.02545
STAT1 signal transducer and activator of transcription 1, 91kDa 3.01848
RSAD2 radical S-adenosyl methionine domain containing 2 3.01785
IL6 interleukin 6 2.9787
SLC27A3 solute carrier family 27 (fatty acid transporter), member 3 2.9762
ISG15 ISG15 ubiquitin-like modifier 2.95875
WARS1 tryptophanyl-tRNA synthetase 1 2.941
PID1 phosphotyrosine interaction domain containing 1 2.9331
IL24 interleukin 24 2.9322
GH1 growth hormone 1 2.92981
CHAC1 ChaC glutathione-specific gamma-glutamylcyclotransferase 1 2.9281
ENTPD1 ectonucleoside triphosphate diphosphohydrolase 1 2.91212
IDO1 indoleamine 2,3-dioxygenase 1 2.90885
NCK2 NCK adaptor protein 2 2.8894
SOD2 superoxide dismutase 2, mitochondrial 2.8753
TENT4A terminal nucleotidyltransferase 4A 2.8665
PPFIA1 protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 1 2.85481
TMC5 transmembrane channel-like 5 2.8395
CLNS1A chloride channel, nucleotide-sensitive, 1A 2.82885
CPA4 carboxypeptidase A4 2.8079
PARP12 poly (ADP-ribose) polymerase family, member 12 2.7996
ALAS1 5'-aminolevulinate synthase 1 2.7981
CDCP1 CUB domain containing protein 1 2.7901
CERK ceramide kinase 2.7852
TLR8 toll-like receptor 8 2.75865
RELB v-rel avian reticuloendotheliosis viral oncogene homolog B 2.75355
PYCR1 pyrroline-5-carboxylate reductase 1 2.73515
RASAL1 RAS protein activator like 1 (GAP1 like) 2.7331
TBC1D31 TBC1 domain family, member 31 2.7244
SDF2L1 stromal cell-derived factor 2-like 1 2.72285
HYI hydroxypyruvate isomerase (putative) 2.708
SPINT1 serine peptidase inhibitor, Kunitz type 1 2.70225
GARS1 glycyl-tRNA synthetase 1 2.6882
TECPR2 tectonin beta-propeller repeat containing 2 2.68725
SCO2 SCO2 cytochrome c oxidase assembly protein 2.68555
MZB1 marginal zone B and B1 cell-specific protein 2.6848
CXCR1 chemokine (C-X-C motif) receptor 1 2.6817
DNAJC4 DnaJ (Hsp40) homolog, subfamily C, member 4 2.6581
CHIC2 cysteine-rich hydrophobic domain 2 2.65565
KLC3 kinesin light chain 3 2.6469
FCER1G Fc fragment of IgE, high affinity I, receptor for; gamma polypeptide 2.6275
ERVMER34-1 endogenous retrovirus group MER34, member 1 2.6266
TRAPPC6A trafficking protein particle complex 6A 2.62185
APOL1 apolipoprotein L, 1 2.62135
C2CD2 C2 calcium-dependent domain containing 2 2.60505
PMP22 peripheral myelin protein 22 2.60451
TJAP1 tight junction associated protein 1 (peripheral) 2.59888
CCNJL cyclin J-like 2.5825
CDPF1 cysteine-rich, DPF motif domain containing 1 2.57935
CTSL cathepsin L 2.57675
KLHDC2 kelch domain containing 2 2.5731
FBLN2 fibulin 2 2.57045
GORASP2 golgi reassembly stacking protein 2, 55kDa 2.56098
CCR2 chemokine (C-C motif) receptor 2 2.55998
PLA2G4A phospholipase A2, group IVA (cytosolic, calcium-dependent) 2.54835
LOC114841035 uncharacterized LOC114841035 2.53075
CSF3 colony stimulating factor 3 (granulocyte) 2.53045
HMOX1 heme oxygenase 1 2.5304
FICD FIC domain containing 2.5262
CSF2 colony stimulating factor 2 (granulocyte-macrophage) 2.5234
GNAZ guanine nucleotide binding protein (G protein), alpha z polypeptide 2.52185
WDR13 WD repeat domain 13 2.51525
MNDA myeloid cell nuclear differentiation antigen 2.51415
TIMP2 TIMP metallopeptidase inhibitor 2 2.5128
MMP2 matrix metallopeptidase 2 2.5061
CXCL3 chemokine (C-X-C motif) ligand 3 2.4967
ADAM9 ADAM metallopeptidase domain 9 2.49595
OAS2 2'-5'-oligoadenylate synthetase 2, 69/71kDa 2.49425
HYOU1 hypoxia up-regulated 1 2.49025
SNTA1 syntrophin, alpha 1 2.48925
SPCS2 signal peptidase complex subunit 2 homolog (S. cerevisiae) 2.48058
GDI1 GDP dissociation inhibitor 1 2.469
OLFM4 olfactomedin 4 2.4682
ST6GALNAC4 ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 4 2.46692
G0S2 G0/G1 switch 2 2.4663
KIAA0930 KIAA0930 2.4626
STIP1 stress-induced phosphoprotein 1 2.46182
IFI6 interferon, alpha-inducible protein 6 2.461
UTP14A UTP14, U3 small nucleolar ribonucleoprotein, homolog A (yeast) 2.46015
CEP72 centrosomal protein 72kDa 2.454
XAF1 XIAP associated factor 1 2.4529
ALPK1 alpha-kinase 1 2.45205
ZHX2 zinc fingers and homeoboxes 2 2.45115
CCPG1 cell cycle progression 1 2.44865
SLCO4A1 solute carrier organic anion transporter family, member 4A1 2.44825
KCNK3 potassium channel, two pore domain subfamily K, member 3 2.44685
OSBPL2 oxysterol binding protein-like 2 2.44263
CREB3L2 cAMP responsive element binding protein 3-like 2 2.43395
FCHSD2 FCH and double SH3 domains 2 2.4316
EXOC3 exocyst complex component 3 2.43125
IL1A interleukin 1, alpha 2.43065
IRF7 interferon regulatory factor 7 2.42775
SLC12A9 solute carrier family 12, member 9 2.4277
RAP1GAP RAP1 GTPase activating protein 2.422
C4BPA complement component 4 binding protein, alpha 2.4143
BTG2 BTG family, member 2 2.41405
PLA2G7 phospholipase A2, group VII (platelet-activating factor acetylhydrolase, plasma) 2.4134
HSPA2 heat shock 70kDa protein 2 2.4117
FAM50A family with sequence similarity 50, member A 2.41045
TLR2 toll-like receptor 2 2.40975
DNAJC17 DnaJ (Hsp40) homolog, subfamily C, member 17 2.4093
CXCL11 chemokine (C-X-C motif) ligand 11 2.4088
TIPARP TCDD-inducible poly(ADP-ribose) polymerase 2.40735
SLC28A3 solute carrier family 28 (concentrative nucleoside transporter), member 3 2.4054
PMM2 phosphomannomutase 2 2.40005
CYBB cytochrome b-245, beta polypeptide 2.39815
PPME1 protein phosphatase methylesterase 1 2.39723
ROGDI rogdi homolog (Drosophila) 2.39665
RFNG RFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase 2.39545
CXCL1 chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha) 2.39365
KCTD17 potassium channel tetramerization domain containing 17 2.3934
LRP10 low density lipoprotein receptor-related protein 10 2.3899
RIGI RNA sensor RIG-I 2.38895
HLA-G major histocompatibility complex, class I, G 2.38028
ADAP2 ArfGAP with dual PH domains 2 2.37735
HLA-F major histocompatibility complex, class I, F 2.37422
LPGAT1 lysophosphatidylglycerol acyltransferase 1 2.3717
FPR2 formyl peptide receptor 2 2.37035
PIM2 Pim-2 proto-oncogene, serine/threonine kinase 2.36775
ALOX5 arachidonate 5-lipoxygenase 2.36527
YBX3 Y box binding protein 3 2.36438
CDIPT CDP-diacylglycerol--inositol 3-phosphatidyltransferase 2.3585
KCNJ2 potassium channel, inwardly rectifying subfamily J, member 2 2.35705
PLEKHG6 pleckstrin homology domain containing, family G (with RhoGef domain) member 6 2.35595
CDH12 cadherin 12, type 2 (N-cadherin 2) 2.3469
UVRAG UV radiation resistance associated 2.34665
RBP4 retinol binding protein 4, plasma 2.34655
CD72 CD72 molecule 2.34535
GALNS galactosamine (N-acetyl)-6-sulfatase 2.3413
TMEM127 transmembrane protein 127 2.33675
TESK1 testis-specific kinase 1 2.33575
IFI35 interferon-induced protein 35 2.33135
TNFRSF1A tumor necrosis factor receptor superfamily, member 1A 2.32895
C2CD3 C2 calcium-dependent domain containing 3 2.32683
NOL3 nucleolar protein 3 (apoptosis repressor with CARD domain) 2.3253
PDXDC1 pyridoxal-dependent decarboxylase domain containing 1 2.32275
FCGR3B Fc fragment of IgG, low affinity IIIb, receptor (CD16b) 2.3182
CCL2 chemokine (C-C motif) ligand 2 2.3142
SIL1 SIL1 nucleotide exchange factor 2.29765
WIPI1 WD repeat domain, phosphoinositide interacting 1 2.2964
FZD10 frizzled class receptor 10 2.2931
KDM6B lysine (K)-specific demethylase 6B 2.29132
SLC25A13 solute carrier family 25 (aspartate/glutamate carrier), member 13 2.2912
CRISP3 cysteine-rich secretory protein 3 2.28695
WDR7 WD repeat domain 7 2.284
LAP3 leucine aminopeptidase 3 2.2792
KIT v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog 2.2791
PSENEN presenilin enhancer gamma secretase subunit 2.27235
RFXANK regulatory factor X-associated ankyrin-containing protein 2.27095
HGSNAT heparan-alpha-glucosaminide N-acetyltransferase 2.2692
PKN1 protein kinase N1 2.2692
ELAPOR1 endosome-lysosome associated apoptosis and autophagy regulator 1 2.2674
KCNJ15 potassium channel, inwardly rectifying subfamily J, member 15 2.26728
GREM1 gremlin 1, DAN family BMP antagonist 2.2664
COA4 cytochrome c oxidase assembly factor 4 homolog (S. cerevisiae) 2.26555
ARHGAP44 Rho GTPase activating protein 44 2.2614
FUT1 fucosyltransferase 1 (galactoside 2-alpha-L-fucosyltransferase, H blood group) 2.2537
TMEM184B transmembrane protein 184B 2.24965
GPN2 GPN-loop GTPase 2 2.24705
MYL9 myosin, light chain 9, regulatory 2.2437
VPREB3 pre-B lymphocyte 3 2.2404
ZC3H12A zinc finger CCCH-type containing 12A 2.2336
SECTM1 secreted and transmembrane 1 2.23135
EIF2AK3 eukaryotic translation initiation factor 2-alpha kinase 3 2.2294
STC1 stanniocalcin 1 2.22542
RAB36 RAB36, member RAS oncogene family 2.21615
PSMB9 proteasome (prosome, macropain) subunit, beta type, 9 2.21395
CANT1 calcium activated nucleotidase 1 2.21392
TFE3 transcription factor binding to IGHM enhancer 3 2.21352
GBP1 guanylate binding protein 1, interferon-inducible 2.20785
CDC42EP2 CDC42 effector protein (Rho GTPase binding) 2 2.20548
MANF mesencephalic astrocyte-derived neurotrophic factor 2.2032
S100A12 S100 calcium binding protein A12 2.2022
ABCA2 ATP-binding cassette, sub-family A (ABC1), member 2 2.2012
GTF3C1 general transcription factor IIIC, polypeptide 1, alpha 220kDa 2.1995
ASMTL acetylserotonin O-methyltransferase-like 2.1941
FOXF1 forkhead box F1 2.19355
HCAR3 hydroxycarboxylic acid receptor 3 2.19335
TPD52L2 tumor protein D52-like 2 2.19225
ST18 suppression of tumorigenicity 18, zinc finger 2.1918
RAB26 RAB26, member RAS oncogene family 2.1912
TMEM161A transmembrane protein 161A 2.19058
JCHAIN joining chain of multimeric IgA and IgM 2.18865
HHEX hematopoietically expressed homeobox 2.18808
TNFSF12-TNFSF13 TNFSF12-TNFSF13 readthrough 2.18765
MT1F metallothionein 1F 2.18738
EDEM1 ER degradation enhancer, mannosidase alpha-like 1 2.1834
IFNGR2 interferon gamma receptor 2 (interferon gamma transducer 1) 2.182
CCS copper chaperone for superoxide dismutase 2.17885
FCGR1A Fc fragment of IgG, high affinity Ia, receptor (CD64) 2.17815
TMEM265 transmembrane protein 265 2.17797
TERF2 telomeric repeat binding factor 2 2.1774
DSE dermatan sulfate epimerase 2.1767
FURIN furin (paired basic amino acid cleaving enzyme) 2.17655
SARAF store-operated calcium entry-associated regulatory factor 2.1711
RCBTB2 regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 2 2.1706
RAI2 retinoic acid induced 2 2.16905
PROCR protein C receptor, endothelial 2.16895
DNMT3A DNA (cytosine-5-)-methyltransferase 3 alpha 2.16525
HLA-DMB major histocompatibility complex, class II, DM beta 2.1647
PPP2R3B protein phosphatase 2, regulatory subunit B'', beta 2.1557
CXCR2 chemokine (C-X-C motif) receptor 2 2.1512
DNAJB2 DnaJ (Hsp40) homolog, subfamily B, member 2 2.14875
BRD9 bromodomain containing 9 2.1485
SLC7A11 solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 2.14833
ZC2HC1A zinc finger, C2HC-type containing 1A 2.14595
SLC2A6 solute carrier family 2 (facilitated glucose transporter), member 6 2.13805
RNASE6 ribonuclease, RNase A family, k6 2.13675
SLC2A10 solute carrier family 2 (facilitated glucose transporter), member 10 2.13665
IFIT3 interferon-induced protein with tetratricopeptide repeats 3 2.1336
RRAGC Ras-related GTP binding C 2.1318
TNFSF14 tumor necrosis factor (ligand) superfamily, member 14 2.1307
TRIM13 tripartite motif containing 13 2.1289
XYLT1 xylosyltransferase I 2.1239
PSMD2 proteasome (prosome, macropain) 26S subunit, non-ATPase, 2 2.1218
TXNDC15 thioredoxin domain containing 15 2.1143
ADGRE3 adhesion G protein-coupled receptor E3 2.11195
PTGS1 prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase) 2.11113
NECAB2 N-terminal EF-hand calcium binding protein 2 2.1098
KLHL21 kelch-like family member 21 2.10875
SART1 squamous cell carcinoma antigen recognized by T cells 2.10765
EIF3CL eukaryotic translation initiation factor 3, subunit C-like 2.10692
HSPA1A heat shock 70kDa protein 1A 2.1064
CRTC3 CREB regulated transcription coactivator 3 2.1046
UGDH UDP-glucose 6-dehydrogenase 2.1018
FGF3 fibroblast growth factor 3 2.10015
LCN2 lipocalin 2 2.0999
ZNF423 zinc finger protein 423 2.0989
ABHD14A abhydrolase domain containing 14A 2.09865
PLBD1 phospholipase B domain containing 1 2.09795
NADK NAD kinase 2.09614
NTSR2 neurotensin receptor 2 2.0952
CD55 CD55 molecule, decay accelerating factor for complement (Cromer blood group) 2.09487
CCL4 chemokine (C-C motif) ligand 4 2.09315
SYNE3 spectrin repeat containing, nuclear envelope family member 3 2.093
PIGR polymeric immunoglobulin receptor 2.0921
FFAR3 free fatty acid receptor 3 2.09165
PTHLH parathyroid hormone-like hormone 2.09058
MMP1 matrix metallopeptidase 1 2.08728
PDZK1IP1 PDZK1 interacting protein 1 2.08445
PLA2G12A phospholipase A2, group XIIA 2.0832
SHMT2 serine hydroxymethyltransferase 2 (mitochondrial) 2.0824
FCGR2A Fc fragment of IgG, low affinity IIa, receptor (CD32) 2.0822
CD101 CD101 molecule 2.0808
ZNF764 zinc finger protein 764 2.07905
GDE1 glycerophosphodiester phosphodiesterase 1 2.077
HIP1R huntingtin interacting protein 1 related 2.07425
DRAP1 DR1-associated protein 1 (negative cofactor 2 alpha) 2.0737
MZT2A mitotic spindle organizing protein 2A 2.0709
BCORL1 BCL6 corepressor-like 1 2.0704
IRX4 iroquois homeobox 4 2.0697
ATP2A3 ATPase, Ca++ transporting, ubiquitous 2.06737
ELAC2 elaC ribonuclease Z 2 2.06655
CSH2 chorionic somatomammotropin hormone 2 2.06435
ABR active BCR-related 2.06273
RRBP1 ribosome binding protein 1 2.06025
WIF1 WNT inhibitory factor 1 2.0585
APOL3 apolipoprotein L, 3 2.0577
IL22RA1 interleukin 22 receptor, alpha 1 2.0553
CSHL1 chorionic somatomammotropin hormone-like 1 2.05355
XDH xanthine dehydrogenase 2.0517
TSTD1 thiosulfate sulfurtransferase (rhodanese)-like domain containing 1 2.051
ABCC8 ATP-binding cassette, sub-family C (CFTR/MRP), member 8 2.05075
NXN nucleoredoxin 2.0495
ALG3 ALG3, alpha-1,3- mannosyltransferase 2.04885
CSRNP2 cysteine-serine-rich nuclear protein 2 2.04775
TXNL4B thioredoxin-like 4B 2.0476
SDC4 syndecan 4 2.0472
CALCOCO1 calcium binding and coiled-coil domain 1 2.04695
ZNF358 zinc finger protein 358 2.0467
GAREM1 GRB2 associated regulator of MAPK1 subtype 1 2.0441
P4HB prolyl 4-hydroxylase, beta polypeptide 2.04352
KIF16B kinesin family member 16B 2.04245
CHPF2 chondroitin polymerizing factor 2 2.04152
IRF6 interferon regulatory factor 6 2.0407
HSPA1B heat shock 70kDa protein 1B 2.03988
AUP1 ancient ubiquitous protein 1 2.039
TCF20 transcription factor 20 (AR1) 2.03835
NDUFS6 NADH dehydrogenase (ubiquinone) Fe-S protein 6, 13kDa (NADH-coenzyme Q reductase) 2.03815
FBXL12 F-box and leucine-rich repeat protein 12 2.03435
CNKSR1 connector enhancer of kinase suppressor of Ras 1 2.03075
TIMM17B translocase of inner mitochondrial membrane 17 homolog B (yeast) 2.0286
TAPBPL TAP binding protein-like 2.0258
DOK7 docking protein 7 2.02177
FOXK2 forkhead box K2 2.02175
SEPHS2 selenophosphate synthetase 2 2.02095
IFI27 interferon, alpha-inducible protein 27 2.01915
INPP5J inositol polyphosphate-5-phosphatase J 2.01815
OTUB2 OTU deubiquitinase, ubiquitin aldehyde binding 2 2.0165
CAVIN3 caveolae associated protein 3 2.0141
TMEM176B transmembrane protein 176B 2.01405
LPAR3 lysophosphatidic acid receptor 3 2.00985
CHN1 chimerin 1 2.00845
TNFRSF6B tumor necrosis factor receptor superfamily, member 6b, decoy 2.00815
APLP1 amyloid beta (A4) precursor-like protein 1 2.0073
NKX2-1 NK2 homeobox 1 2.00717
KHDC1L KH homology domain containing 1-like 2.00515
FOXF2 forkhead box F2 2.0046
TEX11 testis expressed 11 2.0028
FAT1 FAT atypical cadherin 1 2.0019

decreased expression

Symbol Name Standardized Value
MSMO1 methylsterol monooxygenase 1 -10.0
DCK deoxycytidine kinase -7.58555
STMN1 stathmin 1 -6.5783
EZH2 enhancer of zeste 2 polycomb repressive complex 2 subunit -5.8536
CCNB2 cyclin B2 -5.80285
C1QBP complement component 1, q subcomponent binding protein -5.63672
CDK1 cyclin-dependent kinase 1 -5.58683
UBE2C ubiquitin-conjugating enzyme E2C -5.4025
HOXA5 homeobox A5 -5.24525
IARS2 isoleucyl-tRNA synthetase 2, mitochondrial -4.94685
CLPX caseinolytic mitochondrial matrix peptidase chaperone subunit -4.42925
SH3D19 SH3 domain containing 19 -4.32877
UFM1 ubiquitin-fold modifier 1 -4.3182
UQCR10 ubiquinol-cytochrome c reductase, complex III subunit X -4.28505
KIF20A kinesin family member 20A -4.2778
CDC20 cell division cycle 20 -4.17955
CCNA2 cyclin A2 -4.12698
POLE2 polymerase (DNA directed), epsilon 2, accessory subunit -4.07535
PLK1 polo-like kinase 1 -4.04475
BID BH3 interacting domain death agonist -3.99922
CDKN3 cyclin-dependent kinase inhibitor 3 -3.89565
HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) -3.8821
CDK7 cyclin-dependent kinase 7 -3.8206
ANXA2 annexin A2 -3.78828
MAD2L1 MAD2 mitotic arrest deficient-like 1 (yeast) -3.76345
ADH5 alcohol dehydrogenase 5 (class III), chi polypeptide -3.7222
IDI1 isopentenyl-diphosphate delta isomerase 1 -3.661
PARP2 poly (ADP-ribose) polymerase 2 -3.57998
SDHB succinate dehydrogenase complex, subunit B, iron sulfur (Ip) -3.53795
GTF2A2 general transcription factor IIA, 2, 12kDa -3.49865
CETP cholesteryl ester transfer protein, plasma -3.4862
RFC3 replication factor C (activator 1) 3, 38kDa -3.4323
HMGB2 high mobility group box 2 -3.42245
MRPL39 mitochondrial ribosomal protein L39 -3.40495
TOP2A topoisomerase (DNA) II alpha 170kDa -3.40403
NEK2 NIMA-related kinase 2 -3.4027
KIF4A kinesin family member 4A -3.39455
INSIG1 insulin induced gene 1 -3.39437
EXOSC8 exosome component 8 -3.3694
HMGCR 3-hydroxy-3-methylglutaryl-CoA reductase -3.36215
POLA2 polymerase (DNA directed), alpha 2, accessory subunit -3.3395
THOC7 THO complex 7 -3.33795
SESN1 sestrin 1 -3.3211
SOAT2 sterol O-acyltransferase 2 -3.3149
NCAPG2 non-SMC condensin II complex, subunit G2 -3.29945
GADD45B growth arrest and DNA-damage-inducible, beta -3.22138
ACP6 acid phosphatase 6, lysophosphatidic -3.22085
BIRC5 baculoviral IAP repeat containing 5 -3.20075
MOCS2 molybdenum cofactor synthesis 2 -3.17465
HADH hydroxyacyl-CoA dehydrogenase -3.17253
XPO1 exportin 1 -3.1463
OXSM 3-oxoacyl-ACP synthase, mitochondrial -3.1375
HACD2 3-hydroxyacyl-CoA dehydratase 2 -3.1282
CENPN centromere protein N -3.1246
STAC SH3 and cysteine rich domain -3.1139
HMMR hyaluronan-mediated motility receptor (RHAMM) -3.10535
ZDHHC6 zinc finger, DHHC-type containing 6 -3.09945
RPA3 replication protein A3, 14kDa -3.09845
RGS2 regulator of G-protein signaling 2 -3.08615
ZNF274 zinc finger protein 274 -3.08505
CYCS cytochrome c, somatic -3.07295
TTK TTK protein kinase -3.0632
HJURP Holliday junction recognition protein -3.04915
PPP1R8 protein phosphatase 1, regulatory subunit 8 -3.04515
TSC22D3 TSC22 domain family, member 3 -3.04247
SLC35A5 solute carrier family 35, member A5 -3.0239
DLGAP5 discs, large (Drosophila) homolog-associated protein 5 -3.02
TACC3 transforming, acidic coiled-coil containing protein 3 -3.01195
RACGAP1 Rac GTPase activating protein 1 -2.9616
KHDC4 KH domain containing 4, pre-mRNA splicing factor -2.9534
CKS1B CDC28 protein kinase regulatory subunit 1B -2.95115
LDHD lactate dehydrogenase D -2.9419
SHCBP1 SHC SH2-domain binding protein 1 -2.922
BTAF1 BTAF1 RNA polymerase II, B-TFIID transcription factor-associated, 170kDa -2.9174
NSDHL NAD(P) dependent steroid dehydrogenase-like -2.91313
PTCD3 pentatricopeptide repeat domain 3 -2.90395
CENPA centromere protein A -2.89845
UBA2 ubiquitin-like modifier activating enzyme 2 -2.8869
DTYMK deoxythymidylate kinase (thymidylate kinase) -2.87375
HTRA1 HtrA serine peptidase 1 -2.85725
ARPC5 actin related protein 2/3 complex, subunit 5, 16kDa -2.83745
NLRP2B NLR family pyrin domain containing 2B -2.8276
ITGAE integrin, alpha E (antigen CD103, human mucosal lymphocyte antigen 1; alpha polypeptide) -2.8268
COQ6 coenzyme Q6 monooxygenase -2.8199
EAPP E2F-associated phosphoprotein -2.8104
ZNF443 zinc finger protein 443 -2.80905
LSM3 LSM3 homolog, U6 small nuclear RNA associated (S. cerevisiae) -2.80695
MIS18A MIS18 kinetochore protein A -2.78665
ANP32E acidic (leucine-rich) nuclear phosphoprotein 32 family, member E -2.78377
RPL39L ribosomal protein L39-like -2.78045
KIF2C kinesin family member 2C -2.777
CEP55 centrosomal protein 55kDa -2.77305
ECD ecdysoneless homolog (Drosophila) -2.7713
ALDH7A1 aldehyde dehydrogenase 7 family, member A1 -2.77053
ASF1B anti-silencing function 1B histone chaperone -2.7609
BZW2 basic leucine zipper and W2 domains 2 -2.7605
COQ3 coenzyme Q3 methyltransferase -2.7573
CENPU centromere protein U -2.75525
KIF23 kinesin family member 23 -2.75485
POLR2K polymerase (RNA) II (DNA directed) polypeptide K, 7.0kDa -2.75467
AKAP11 A kinase (PRKA) anchor protein 11 -2.7511
NUP85 nucleoporin 85kDa -2.7405
GAP43 growth associated protein 43 -2.73975
FRG1 FSHD region gene 1 -2.73835
HAUS4 HAUS augmin-like complex, subunit 4 -2.7375
KANSL2 KAT8 regulatory NSL complex subunit 2 -2.7367
HSD17B11 hydroxysteroid (17-beta) dehydrogenase 11 -2.724
TRH thyrotropin-releasing hormone -2.72245
PRKCH protein kinase C, eta -2.71718
PSPC1 paraspeckle component 1 -2.7162
GALNT11 polypeptide N-acetylgalactosaminyltransferase 11 -2.7063
UBA3 ubiquitin-like modifier activating enzyme 3 -2.703
TPX2 TPX2, microtubule-associated -2.6964
PDHB pyruvate dehydrogenase (lipoamide) beta -2.6932
ARL6IP1 ADP-ribosylation factor-like 6 interacting protein 1 -2.69305
HSPB1 heat shock 27kDa protein 1 -2.6849
GEMIN2 gem (nuclear organelle) associated protein 2 -2.67891
PBK PDZ binding kinase -2.663
SUCLG2 succinate-CoA ligase, GDP-forming, beta subunit -2.63205
DARS2 aspartyl-tRNA synthetase 2, mitochondrial -2.62895
ZNF185 zinc finger protein 185 (LIM domain) -2.6287
DAAM1 dishevelled associated activator of morphogenesis 1 -2.61805
ASPM asp (abnormal spindle) homolog, microcephaly associated (Drosophila) -2.61535
MRPL3 mitochondrial ribosomal protein L3 -2.6067
TCEAL4 transcription elongation factor A (SII)-like 4 -2.6045
CRIPT cysteine-rich PDZ-binding protein -2.60445
SEC23A Sec23 homolog A (S. cerevisiae) -2.60287
PSMG1 proteasome (prosome, macropain) assembly chaperone 1 -2.6022
ACOT2 acyl-CoA thioesterase 2 -2.6019
ITGB3BP integrin beta 3 binding protein (beta3-endonexin) -2.5869
NUSAP1 nucleolar and spindle associated protein 1 -2.5775
NPY neuropeptide Y -2.57355
POLE3 polymerase (DNA directed), epsilon 3, accessory subunit -2.56765
PAFAH1B3 platelet-activating factor acetylhydrolase 1b, catalytic subunit 3 (29kDa) -2.56435
CKS2 CDC28 protein kinase regulatory subunit 2 -2.5533
INTS12 integrator complex subunit 12 -2.55015
CUTC cutC copper transporter -2.54705
TBP TATA box binding protein -2.5432
PRC1 protein regulator of cytokinesis 1 -2.54085
CASP8AP2 caspase 8 associated protein 2 -2.5354
SLC9A3R1 solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 1 -2.52935
CNIH3 cornichon family AMPA receptor auxiliary protein 3 -2.5276
PEX3 peroxisomal biogenesis factor 3 -2.52408
NPHS2 nephrosis 2, idiopathic, steroid-resistant (podocin) -2.5234
HMGN1 high mobility group nucleosome binding domain 1 -2.5123
ABCE1 ATP-binding cassette, sub-family E (OABP), member 1 -2.50865
MDH1 malate dehydrogenase 1, NAD (soluble) -2.50845
USPL1 ubiquitin specific peptidase like 1 -2.49415
GINS2 GINS complex subunit 2 (Psf2 homolog) -2.4872
ATP5PF ATP synthase peripheral stalk subunit F6 -2.47085
GPN3 GPN-loop GTPase 3 -2.4666
KIAA0586 KIAA0586 -2.45885
BCKDHB branched chain keto acid dehydrogenase E1, beta polypeptide -2.45835
UBE2E1 ubiquitin-conjugating enzyme E2E 1 -2.4579
TFB2M transcription factor B2, mitochondrial -2.45225
LETMD1 LETM1 domain containing 1 -2.45175
NEIL3 nei endonuclease VIII-like 3 (E. coli) -2.44555
MICU2 mitochondrial calcium uptake 2 -2.4427
NIT2 nitrilase family, member 2 -2.4419
AURKA aurora kinase A -2.43963
ZWILCH zwilch kinetochore protein -2.43915
MRPS16 mitochondrial ribosomal protein S16 -2.4389
UBXN8 UBX domain protein 8 -2.4365
HOXA1 homeobox A1 -2.42815
RPP40 ribonuclease P/MRP 40kDa subunit -2.4255
GDI2 GDP dissociation inhibitor 2 -2.4218
LGR4 leucine-rich repeat containing G protein-coupled receptor 4 -2.41925
CDCA3 cell division cycle associated 3 -2.40815
NDUFB6 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 6, 17kDa -2.40725
STARD13 StAR-related lipid transfer (START) domain containing 13 -2.4063
NMD3 NMD3 ribosome export adaptor -2.4032
FDFT1 farnesyl-diphosphate farnesyltransferase 1 -2.39598
S100A10 S100 calcium binding protein A10 -2.3945
TRMO tRNA methyltransferase O -2.39415
RMND1 required for meiotic nuclear division 1 homolog (S. cerevisiae) -2.38785
THYN1 thymocyte nuclear protein 1 -2.3851
CRYBG1 crystallin beta-gamma domain containing 1 -2.37075
SMYD2 SET and MYND domain containing 2 -2.36915
ZNF26 zinc finger protein 26 -2.36835
PCCB propionyl CoA carboxylase, beta polypeptide -2.35805
ANGPTL7 angiopoietin-like 7 -2.35775
MAB21L4 mab-21 like 4 -2.3558
NUP54 nucleoporin 54kDa -2.35335
CDC23 cell division cycle 23 -2.3466
DCLRE1A DNA cross-link repair 1A -2.3453
KIF14 kinesin family member 14 -2.3437
FIRRM FIGNL1 interacting regulator of recombination and mitosis -2.34355
SIRAL2 SIR2 antiphage like 2 -2.3411
NUP205 nucleoporin 205kDa -2.33885
METTL18 methyltransferase like 18 -2.33565
ACLY ATP citrate lyase -2.33163
NUS1 nuclear undecaprenyl pyrophosphate synthase 1 homolog (S. cerevisiae) -2.33045
FXN frataxin -2.32815
FLNB filamin B, beta -2.32212
ADGRB3 adhesion G protein-coupled receptor B3 -2.32085
KIF11 kinesin family member 11 -2.31645
PCNT pericentrin -2.31585
CLCN5 chloride channel, voltage-sensitive 5 -2.3141
UIMC1 ubiquitin interaction motif containing 1 -2.31315
LAMTOR3 late endosomal/lysosomal adaptor, MAPK and MTOR activator 3 -2.3102
ALDOC aldolase C, fructose-bisphosphate -2.3099
COMMD10 COMM domain containing 10 -2.2967
HDDC2 HD domain containing 2 -2.29625
ZNF23 zinc finger protein 23 -2.29555
HOXC6 homeobox C6 -2.2933
NUDT21 nudix (nucleoside diphosphate linked moiety X)-type motif 21 -2.291
SPDL1 spindle apparatus coiled-coil protein 1 -2.2877
PLP1 proteolipid protein 1 -2.2876
SPAG5 sperm associated antigen 5 -2.28715
MELK maternal embryonic leucine zipper kinase -2.28255
CTNNAL1 catenin (cadherin-associated protein), alpha-like 1 -2.281
KAT2A K(lysine) acetyltransferase 2A -2.2802
RDH11 retinol dehydrogenase 11 (all-trans/9-cis/11-cis) -2.27997
ABHD2 abhydrolase domain containing 2 -2.27813
CRYL1 crystallin, lambda 1 -2.2778
THEM6 thioesterase superfamily member 6 -2.2737
GHITM growth hormone inducible transmembrane protein -2.27303
UBAP1 ubiquitin associated protein 1 -2.26985
C1QTNF3 C1q and tumor necrosis factor related protein 3 -2.26945
GPHN gephyrin -2.2661
LBR lamin B receptor -2.25605
KDM3A lysine (K)-specific demethylase 3A -2.2546
TCEAL1 transcription elongation factor A (SII)-like 1 -2.2543
CYP51A1 cytochrome P450, family 51, subfamily A, polypeptide 1 -2.2519
NRIP1 nuclear receptor interacting protein 1 -2.24913
ATP5F1C ATP synthase F1 subunit gamma -2.24595
FBXL4 F-box and leucine-rich repeat protein 4 -2.24405
SELL selectin L -2.24315
FCF1 FCF1 rRNA-processing protein -2.24312
DDX50 DEAD (Asp-Glu-Ala-Asp) box polypeptide 50 -2.2413
PRPF4 pre-mRNA processing factor 4 -2.2374
SLC17A1 solute carrier family 17 (organic anion transporter), member 1 -2.2365
ATG5 autophagy related 5 -2.23083
DLAT dihydrolipoamide S-acetyltransferase -2.23017
GCDH glutaryl-CoA dehydrogenase -2.23005
ADI1 acireductone dioxygenase 1 -2.2293
ELOVL6 ELOVL fatty acid elongase 6 -2.22675
SSBP1 single-stranded DNA binding protein 1, mitochondrial -2.22545
SPRED2 sprouty-related, EVH1 domain containing 2 -2.22545
TSPAN6 tetraspanin 6 -2.22237
UQCRH ubiquinol-cytochrome c reductase hinge protein -2.222
LIPT1 lipoyltransferase 1 -2.2208
SCD stearoyl-CoA desaturase (delta-9-desaturase) -2.2171
TMPO thymopoietin -2.21638
POP5 processing of precursor 5, ribonuclease P/MRP subunit (S. cerevisiae) -2.21435
MRPL33 mitochondrial ribosomal protein L33 -2.2123
NAT10 N-acetyltransferase 10 (GCN5-related) -2.2097
GTPBP8 GTP-binding protein 8 (putative) -2.20815
CLIP4 CAP-GLY domain containing linker protein family, member 4 -2.2056
FANCI Fanconi anemia, complementation group I -2.20548
SDHD succinate dehydrogenase complex, subunit D, integral membrane protein -2.2052
CRYZ crystallin, zeta (quinone reductase) -2.2023
LMO7 LIM domain 7 -2.19965
UQCRC1 ubiquinol-cytochrome c reductase core protein I -2.19735
DNASE1L3 deoxyribonuclease I-like 3 -2.1953
TTC1 tetratricopeptide repeat domain 1 -2.1949
BCL11B B-cell CLL/lymphoma 11B (zinc finger protein) -2.19482
MTRF1 mitochondrial translational release factor 1 -2.19345
PGK1 phosphoglycerate kinase 1 -2.19065
TIRAP toll-interleukin 1 receptor (TIR) domain containing adaptor protein -2.18275
HOPX HOP homeobox -2.1788
ERCC6L excision repair cross-complementation group 6-like -2.1757
ABLIM1 actin binding LIM protein 1 -2.17502
CKAP2 cytoskeleton associated protein 2 -2.1741
BUB3 BUB3 mitotic checkpoint protein -2.17285
CZIB CXXC motif containing zinc binding protein -2.1727
NT5DC2 5'-nucleotidase domain containing 2 -2.1713
ANGPT1 angiopoietin 1 -2.17013
ADGRE5 adhesion G protein-coupled receptor E5 -2.1649
ZNF211 zinc finger protein 211 -2.1648
PLCG1 phospholipase C, gamma 1 -2.1625
F2R coagulation factor II (thrombin) receptor -2.16235
NCAPD3 non-SMC condensin II complex, subunit D3 -2.15895
CHEK2 checkpoint kinase 2 -2.15765
TMEM242 transmembrane protein 242 -2.15705
CAPRIN1 cell cycle associated protein 1 -2.15363
MYZAP myocardial zonula adherens protein -2.14908
MRPL17 mitochondrial ribosomal protein L17 -2.1486
ACY1 aminoacylase 1 -2.14475
SINHCAF SIN3-HDAC complex associated factor -2.1416
SNUPN snurportin 1 -2.13665
GMDS GDP-mannose 4,6-dehydratase -2.13628
YKT6 YKT6 v-SNARE homolog (S. cerevisiae) -2.13602
CBX3 chromobox homolog 3 -2.13363
HOXA4 homeobox A4 -2.1329
SNRPE small nuclear ribonucleoprotein polypeptide E -2.12625
SIGLEC15 sialic acid binding Ig-like lectin 15 -2.12585
PRKD3 protein kinase D3 -2.12585
ZXDC ZXD family zinc finger C -2.12375
PPIH peptidylprolyl isomerase H (cyclophilin H) -2.12295
FANCC Fanconi anemia, complementation group C -2.12015
PRPF18 pre-mRNA processing factor 18 -2.1141
MRPL15 mitochondrial ribosomal protein L15 -2.11015
PEX7 peroxisomal biogenesis factor 7 -2.10755
ECHDC1 ethylmalonyl-CoA decarboxylase 1 -2.10745
DONSON downstream neighbor of SON -2.10335
HSD17B7 hydroxysteroid (17-beta) dehydrogenase 7 -2.1011
NUDT1 nudix (nucleoside diphosphate linked moiety X)-type motif 1 -2.09265
DHCR7 7-dehydrocholesterol reductase -2.0922
RPP30 ribonuclease P/MRP 30kDa subunit -2.0922
REST RE1-silencing transcription factor -2.09002
DNAJC9 DnaJ (Hsp40) homolog, subfamily C, member 9 -2.08977
CCNB1 cyclin B1 -2.0885
TMOD3 tropomodulin 3 (ubiquitous) -2.08785
MCM3 minichromosome maintenance complex component 3 -2.08675
ATP1A4 ATPase, Na+/K+ transporting, alpha 4 polypeptide -2.0862
DHTKD1 dehydrogenase E1 and transketolase domain containing 1 -2.0839
CASC3 cancer susceptibility candidate 3 -2.0824
RANBP9 RAN binding protein 9 -2.08128
FBXO5 F-box protein 5 -2.08045
STAT5B signal transducer and activator of transcription 5B -2.07983
MNAT1 MNAT CDK-activating kinase assembly factor 1 -2.0749
CSTF3 cleavage stimulation factor, 3' pre-RNA, subunit 3, 77kDa -2.0744
OARD1 O-acyl-ADP-ribose deacylase 1 -2.07365
MRPL16 mitochondrial ribosomal protein L16 -2.0733
GNL3 guanine nucleotide binding protein-like 3 (nucleolar) -2.06465
PALS2 protein associated with LIN7 2, MAGUK p55 family member -2.06125
NPR2 natriuretic peptide receptor 2 -2.05833
SCML1 sex comb on midleg-like 1 (Drosophila) -2.0582
EGLN1 egl-9 family hypoxia-inducible factor 1 -2.0566
CCNC cyclin C -2.0562
RGS4 regulator of G-protein signaling 4 -2.04785
HMGB1 high mobility group box 1 -2.0465
DCTD dCMP deaminase -2.04598
GPBP1L1 GC-rich promoter binding protein 1-like 1 -2.04245
GTF3A general transcription factor IIIA -2.03985
EED embryonic ectoderm development -2.0396
ASF1A anti-silencing function 1A histone chaperone -2.03937
RUSC1 RUN and SH3 domain containing 1 -2.03923
WWTR1 WW domain containing transcription regulator 1 -2.0354
COMMD3-BMI1 COMMD3-BMI1 readthrough -2.03255
INTS3 integrator complex subunit 3 -2.026
CDC123 cell division cycle 123 -2.02535
ENOPH1 enolase-phosphatase 1 -2.02375
BBS4 Bardet-Biedl syndrome 4 -2.02203
RFC4 replication factor C (activator 1) 4, 37kDa -2.0193
VCPKMT valosin containing protein lysine (K) methyltransferase -2.0187
TARBP1 TAR (HIV-1) RNA binding protein 1 -2.01605
TMEM100 transmembrane protein 100 -2.0128
SEPTIN7 septin 7 -2.01185
PSIP1 PC4 and SFRS1 interacting protein 1 -2.0107
DAG1 dystroglycan 1 (dystrophin-associated glycoprotein 1) -2.00805
PCNA proliferating cell nuclear antigen -2.00565
NDC1 NDC1 transmembrane nucleoporin -2.0028