CRCGN017_MCF10A.TP53.M_24H:I02 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description o-aminoazotoluene 33.27 um perturbation at 24 h in MCF10A.TP53.M (Carcinogenome)
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Genes

18 genes differentially expressed following the CRCGN017_MCF10A.TP53.M_24H:I02 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
VAV3 vav 3 guanine nucleotide exchange factor 5.2908
PPP2R5E protein phosphatase 2, regulatory subunit B', epsilon isoform 4.84205
FGFR4 fibroblast growth factor receptor 4 4.02922
NUDT9 nudix (nucleoside diphosphate linked moiety X)-type motif 9 4.0197
NUCB2 nucleobindin 2 3.2148
PKIG protein kinase (cAMP-dependent, catalytic) inhibitor gamma 3.0972
COQ8A coenzyme Q8A 2.5139
NFATC4 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 4 2.50625
ABHD6 abhydrolase domain containing 6 2.50613
CCDC85B coiled-coil domain containing 85B 2.3852
BAD BCL2-associated agonist of cell death 2.3574
S100A4 S100 calcium binding protein A4 2.15155
P4HTM prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum) 2.06835

decreased expression

Symbol Name Standardized Value
NRIP1 nuclear receptor interacting protein 1 -2.73077
MTERF3 mitochondrial transcription termination factor 3 -2.37245
RAI14 retinoic acid induced 14 -2.3171
HOXA5 homeobox A5 -2.29125
ANKRD10 ankyrin repeat domain 10 -2.20045