CRCGN017_MCF10A.TP53.M_24H:I05 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description isoniazid 33.43 um perturbation at 24 h in MCF10A.TP53.M (Carcinogenome)
Similar Terms
Downloads & Tools

Genes

20 genes differentially expressed following the CRCGN017_MCF10A.TP53.M_24H:I05 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
CCP110 centriolar coiled coil protein 110kDa 4.19903
ACAA1 acetyl-CoA acyltransferase 1 3.60422
TXNL4B thioredoxin-like 4B 3.25824
IGHMBP2 immunoglobulin mu binding protein 2 3.21794
TGFBR2 transforming growth factor, beta receptor II (70/80kDa) 3.10234
TBC1D31 TBC1 domain family, member 31 3.09943
HERC6 HECT and RLD domain containing E3 ubiquitin protein ligase family member 6 2.81951
EGF epidermal growth factor 2.74919
PLSCR3 phospholipid scramblase 3 2.53471
SLC25A13 solute carrier family 25 (aspartate/glutamate carrier), member 13 2.44795
TPD52L2 tumor protein D52-like 2 2.14676
TIMM17B translocase of inner mitochondrial membrane 17 homolog B (yeast) 2.12784
RBP4 retinol binding protein 4, plasma 2.01724

decreased expression

Symbol Name Standardized Value
C2CD5 C2 calcium-dependent domain containing 5 -4.57605
HMG20B high mobility group 20B -4.11624
SCYL3 SCY1-like 3 (S. cerevisiae) -3.82269
TM9SF2 transmembrane 9 superfamily member 2 -2.95714
HIF1A hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) -2.86957
SLC7A5 solute carrier family 7 (amino acid transporter light chain, L system), member 5 -2.62465
KRT14 keratin 14, type I -2.25322