CRCGN017_MCF10A.TP53.M_24H:I07 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description roxarsone 99.3 um perturbation at 24 h in MCF10A.TP53.M (Carcinogenome)
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Genes

17 genes differentially expressed following the CRCGN017_MCF10A.TP53.M_24H:I07 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
CCL2 chemokine (C-C motif) ligand 2 6.10848
HBA1 hemoglobin, alpha 1 2.32506
HBB hemoglobin, beta 2.24081
CETN3 centrin, EF-hand protein, 3 2.23195
TBPL1 TBP-like 1 2.09364

decreased expression

Symbol Name Standardized Value
NPDC1 neural proliferation, differentiation and control, 1 -6.51473
CD44 CD44 molecule (Indian blood group) -3.96367
HMG20B high mobility group 20B -3.61842
CHMP4B charged multivesicular body protein 4B -3.54486
CANT1 calcium activated nucleotidase 1 -3.06652
CORO1A coronin, actin binding protein, 1A -2.58468
SLC35F2 solute carrier family 35, member F2 -2.40108
SLC7A5 solute carrier family 7 (amino acid transporter light chain, L system), member 5 -2.3911
NT5DC3 5'-nucleotidase domain containing 3 -2.28521
ARPP19 cAMP-regulated phosphoprotein, 19kDa -2.0357
RPA4 replication protein A4, 30kDa -2.02525
NECTIN3 nectin cell adhesion molecule 3 -2.01751