CRCGN017_MCF10A.TP53.M_24H:I11 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description promethazine 33.6 um perturbation at 24 h in MCF10A.TP53.M (Carcinogenome)
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Genes

16 genes differentially expressed following the CRCGN017_MCF10A.TP53.M_24H:I11 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
CXCR4 chemokine (C-X-C motif) receptor 4 4.06621
AGL amylo-alpha-1, 6-glucosidase, 4-alpha-glucanotransferase 4.00547
DDX42 DEAD (Asp-Glu-Ala-Asp) box helicase 42 3.56231
RPL39L ribosomal protein L39-like 3.0688
COQ8A coenzyme Q8A 2.6606
FKBP14 FK506 binding protein 14, 22 kDa 2.62887
EVL Enah/Vasp-like 2.45563
INSIG1 insulin induced gene 1 2.23405
ALDOC aldolase C, fructose-bisphosphate 2.20907
CENPE centromere protein E, 312kDa 2.00841

decreased expression

Symbol Name Standardized Value
ADI1 acireductone dioxygenase 1 -4.09453
PRPF4 pre-mRNA processing factor 4 -3.88504
CDKN1B cyclin-dependent kinase inhibitor 1B (p27, Kip1) -2.9374
TES testin LIM domain protein -2.86311
PRR15L proline rich 15-like -2.4109
HERC6 HECT and RLD domain containing E3 ubiquitin protein ligase family member 6 -2.28579